190 research outputs found
Momentos uma etnografia fotográfica: as mulheres que trabalham no setor de limpeza e conservação na Universidade Federal de Uberlândia
This following work aims to present an ethnographic artistic study of selected women who work in the cleaning and conservation sector at one of the outsourced companies of the Federal University of Uberlândia. I use photography as a language to express my gaze and offer visibility to the position they find themselves at. I describe the characteristics of the sector, the operation and the impact of the ethnographic method. I expose the situations in which they find themselves in the context of the university, and how these circumstances bring about changes in their collective identities. As the study progressed, a photobook consisting of photographs of the profession's universe, a logbook and reports on the obstacles that the women's group faced in 2019 were produced.Trabalho de Conclusão de Curso (Graduação)O presente trabalho objetiva apresentar um estudo artístico de caráter etnográfico sobre algumas mulheres que trabalham no setor de limpeza e conservação por uma das empresas terceirizadas da Universidade Federal de Uberlândia. Utilizo da fotografia como linguagem para expressar meu olhar, e oferecer uma visibilidade à posição em que se encontram. Descrevo as características do setor, o funcionamento e o impacto do método etnográfico. Exponho as situações em que elas se encontram perante a universidade, e como essas circunstâncias trazem alterações em suas identidades coletivas. Conforme o avanço do estudo, foi realizada a produção de um fotolivro composto pelas fotografias do universo da profissão, um diário de bordo e relatos sobre os obstáculos que o grupo de mulheres enfrentou no ano de 2019
BREAKOUT SESSION: Land Use Change & Food Systems in South America
Due to different conservation laws in the Amazon and Cerrado, the Cerrado has become a “sacrifice zone” for deforestation, and between 1985 and 2023, 39 million hectares were deforested. While 43% of plant species are found only in the Cerrado Biome, it is the most unprotected savanna in the world. The greatest threat to the biome is the expansion of croplands, especially soy. This interdisciplinary discussion combined various professional perspectives to investigate the socioeconomic and environmental factors influencing land-use transitions in the Cerrado Biome. Panelists discussed their research on various methods to increase agricultural production to meet global food needs while not negatively impacting native species. Researchers identified trends in land characteristics and the driving factors of agricultural expansion and abandonment, presenting their findings in a range of models, heat-maps, and correlation graphs. Panelists explored current and future solutions, such as Brazil’s Forrest Code (Environmental Law) and the Cerrado de Pe association, which was started in 2017 to provide seeds for restoration projects in the Chapada dos Veadeiros region and has led to the restoration of 90 hectares.https://scholarworks.uvm.edu/fss2024/1020/thumbnail.jp
ACE-2 down-regulation may act as a transient molecular disease causing RAAS dysregulation and tissue damage in the microcirculatory environment among COVID-19 patients
SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), the etiological agent of COVID-19 (coronavirus disease 2019) and the cause of the current pandemic, produces multiform manifestations throughout the body, causing indiscriminate damage to multiple organ systems, particularly the lungs, heart, brain, kidney, and vasculature. The aim of this review is to provide a new look at the data already available for COVID-19, exploring it as a transient molecular disease that causes negative regulation of ACE-2 (angiotensin-converting enzyme 2) and, consequently, deregulates the renin-angiotensin-aldosterone system (RAAS), promoting important changes in the microcirculatory environment. In addition, the authors seek to demonstrate how these microcirculatory changes may be responsible for the wide variety of injury mechanisms observed in different organs in this disease. This new proposed concept of COVID-19 provides a unifying pathophysiological picture of this infection and offers new insights for a rational treatment strategy to combat this new pandemic
Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation
Canonical Wnt signaling has been implicated in various aspects of hematopoiesis. Its role is controversial due to different outcomes between various inducible Wnt-signaling loss-of-function models and also compared with gain-of-function systems. We therefore studied a mouse deficient for a Wnt gene that seemed to play a nonredundant role in hematopoiesis. Mice lacking Wnt3a die prenatally around embryonic day (E) 12.5, allowing fetal hematopoiesis to be studied using in vitro assays and transplantation into irradiated recipient mice. Here we show that Wnt3a deficiency leads to a reduction in the numbers of hematopoietic stem cells (HSCs) and progenitor cells in the fetal liver (FL) and to severely reduced reconstitution capacity as measured in secondary transplantation assays. This deficiency is irreversible and cannot be restored by transplantation into Wnt3a competent mice. The impaired long-term repopulation capacity of Wnt3a-/- HSCs could not be explained by altered cell cycle or survival of primitive progenitors. Moreover, Wnt3a deficiency affected myeloid but not B-lymphoid development at the progenitor level, and affected immature thymocyte differentiation. Our results show that Wnt3a signaling not only provides proliferative stimuli, such as for immature thymocytes, but also regulates cell fate decisions of HSC during hematopoiesis
ENGAJAMENTO NO TRABALHO: UM CONSTRUTO DE MÚLTIPLAS ABORDAGENS
No presente artigo busca-se visitar a temática do engajamento no trabalho, condição tão almejada por organizações e profissionais de recursos humanos aos trabalhadores que nela atuam. O objetivo foi analisar a produção acadêmica acerca do engajamento no trabalho, de modo a categorizar diferentes perspectivas teóricas sobre a temática. Nota-se que este construto é visto de maneiras distintas no âmbito das organizações – que almejam, cada vez mais, trabalhadores engajados – e no âmbito acadêmico, onde em geral, o engajamento é visto como um estado difuso de presença psicológica no trabalho que envolve conexão positiva, por vezes afetiva, com o ato de trabalhar marcado pelo emprego de energia, dedicação e concentração nas tarefas. Trata-se de um construto que caiu no senso comum, e justamente por isso, tem seu significado comumente distorcido, de modo que, neste manuscrito, opte-se por debater a relação do engajamento com outros construtos do comportamento organizacional, com o intuito de apresentantar diferenciações e similaridades entre os mesmos. Diferentes autores buscam desde os anos 2000, quando os estudos acadêmicos sobre o tema ganharam corpo, estabelecer bases teórico-metodógicas para a temática, as quais, por vezes, divergem entre si. Neste artigo busca-se demonstrar que apesar da abordagem de Wilmar Schaufeli, pesquisador holandês, ser dominante em estudos da área, inclusive brasileiros, não se trata da única perspectiva de olhar para o tema, existindo autores, inclusive, críticos à elaboração do pesquisador e seus colaboradores. Propõe-se, assim, neste artigo essencialmente teórico, a divisão dos estudos sobre o tema em 4 pesrspectivas teóricas distintas e a proposição de uma conceituação para o construto de modo a viabilizar a operacionalização de estudos empíricos posteriores
RELAÇÕES ENTRE MOTIVAÇÃO, SATISFAÇÃO NO TRABALHO E AS DIMENSÕES COMPETITIVAS DA ESTRATÉGIA DE RECURSOS HUMANOS NO GREAT PLACE TO WORK
Este artigo tem como objetivo verificar a relação entre Motivação, Satisfação dos Trabalhadores e Dimensões Competitivas da Estratégia de Recursos Humanos no contexto da premiação Great Place to Work (GPTW). O questionário do GPTW foi analisado em termos de Dimensões Competitivas da Estratégia de Recursos Humanos, Teoria das Necessidades de Maslow e Satisfação no Trabalho, com o uso da técnica Análise Temática. Como resultado, foi possível verificar que o GPTW avalia a gestão da cultura organizacional associada à necessidade de segurança e relacionamento, predominantemente vinculadas ao suporte oferecido pela chefia e colegas de trabalho. No contexto prático, esta pesquisa contribui para a gestão de recursos humanos com o foco de encontrar maneiras de melhorar o local de trabalho para os trabalhadores
The ACE1 Electrical Impedance Tomography System for Thoracic Imaging
The design and performance of the active complex electrode (ACE1) electrical impedance tomography system for single-ended phasic voltage measurements are presented. The design of the hardware and calibration procedures allows for reconstruction of conductivity and permittivity images. Phase measurement is achieved with the ACE1 active electrode circuit which measures the amplitude and phase of the voltage and the applied current at the location at which current is injected into the body. An evaluation of the system performance under typical operating conditions includes details of demodulation and calibration and an in-depth look at insightful metrics, such as signal-to-noise ratio variations during a single current pattern. Static and dynamic images of conductivity and permittivity are presented from ACE1 data collected on tank phantoms and human subjects to illustrate the system\u27s utility
An Amazon Tipping Point: The Economic and Environmental Fallout
The Amazon biome, despite its resilience, is being pushed by unsustainable economic drivers towards an ecological tipping point where restoration to its previous state may no longer possible. This is the result of self-reinforcing interactions between deforestation, climate change and fire. In this paper, we develop scenarios that represent movement towards an Amazon tipping point and strategies to avert one. We assess the economic, natural capital and ecosystem services impacts of these scenarios using the Integrated Economic-Environmental Modeling (IEEM) Platform linked with high resolution spatial land use land cover change and ecosystem services modeling (IEEM+ESM). This paper’s main contributions are developing: (i) a framework for evaluating strategies to avert an Amazon tipping point based on their relative costs, benefits and trade-offs, and; (ii) a first approximation of the economic, natural capital and ecosystem services impacts of movement towards an Amazon tipping point, and evidence to build the economic case for strategies to avert it. We find that a conservative estimate of the cumulative regional cost through 2050 of an Amazon tipping point would be US339.3 billion in additional wealth. From a public investment perspective, the returns to implementing strategies for averting a tipping point would be US$29.5 billion. Quantifying the costs, benefits and trade-offs of policies to avert a tipping point in a transparent and replicable manner can pave the way for evidence-based approaches to support policy action focusing on the design of regional strategies for the Amazon biome and catalyze global cooperation and financing to enable their implementation.Centro de Estudios Distributivos, Laborales y Sociale
Endothelial Cells Support Persistent Gammaherpesvirus 68 Infection
A variety of human diseases are associated with gammaherpesviruses, including neoplasms of lymphocytes (e.g. Burkitt's lymphoma) and endothelial cells (e.g. Kaposi's sarcoma). Gammaherpesvirus infections usually result in either a productive lytic infection, characterized by expression of all viral genes and rapid cell lysis, or latent infection, characterized by limited viral gene expression and no cell lysis. Here, we report characterization of endothelial cell infection with murine gammaherpesvirus 68 (γHV68), a virus phylogenetically related and biologically similar to the human gammaherpesviruses. Endothelial cells supported γHV68 replication in vitro, but were unique in that a significant proportion of the cells escaped lysis, proliferated, and remained viable in culture for an extended time. Upon infection, endothelial cells became non-adherent and altered in size, complexity, and cell-surface protein expression. These cells were uniformly infected and expressed the lytic transcription program based on detection of abundant viral gene transcripts, GFP fluorescence from the viral genome, and viral surface protein expression. Additionally, endothelial cells continued to produce new infectious virions as late as 30 days post-infection. The outcome of this long-term infection was promoted by the γHV68 v-cyclin, because in the absence of the v-cyclin, viability was significantly reduced following infection. Importantly, infected primary endothelial cells also demonstrated increased viability relative to infected primary fibroblasts, and this increased viability was dependent on the v-cyclin. Finally, we provide evidence for infection of endothelial cells in vivo in immune-deficient mice. The extended viability and virus production of infected endothelial cells indicated that endothelial cells provided a source of prolonged virus production and identify a cell-type specific adaptation of gammaherpesvirus replication. While infected endothelial cells would likely be cleared in a healthy individual, persistently infected endothelial cells could provide a source of continued virus replication in immune-compromised individuals, a context in which gammaherpesvirus-associated pathology frequently occurs
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