Comportamiento del índice de vegetación normalizado de pasturas base alfalfa en la provinciala de Buenos Aires = Behavior of the normalized vegetation index in alfalfa pastures in the center of Buenos Aires province

Publicado en: Revista Argentina de Producción Animal – RAPA 44 (Supl. 1) : 351. (septiembre 2024)Actualmente se ha incrementado el uso de herramientas para el monitoreo y estimación de forraje basados en teledetección, así como aplicaciones de gestión que ofrecen este tipo de información. Entre los productos más difundidos se encuentran los mapas de Índice de Vegetación Normalizado (IVN), el cual permite estimar la proporción de radiación solar absorbida por las plantas para la fotosíntesis, que está muy relacionada con la producción de forraje. El objetivo del trabajo fue caracterizar el comportamiento (valores máximos, mínimos y promedio) del IVN en pasturas base alfalfa (Medicago sativa) en establecimientos del centro de la provincia de Buenos Aires utilizando imágenes de las misiones satelitales Landsat 8 y Sentinel 2.EEA BalcarceFil: Iturralde Elortegui, Maria Del Rosario. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Agencia de Extensión Rural Olavarría; ArgentinaFil: Di Cesare, Genaro . Universidad Católica Argentina (UCA). Facultad de Ingeniería y Ciencias Agrarias; ArgentinaFil: Recavarren, Paulo Mario. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Agencia de Extensión Rural Olavarría; Argentin

Papulose bowenóide: um aspecto clínico da infecção pelo HPV Bowenoid papulosis: a clinical feature of the HPV infection

Papulose bowenóide é uma doença que acomete a pele da região anogenital e que se caracteriza pelas múltiplas pequenas pápulas planas ou aveludadas e de coloração que varia do róseo ao castanho-escuro. É provocada pelo HPV e a transmissão sexual é a forma mais freqüente de contaminação. As queixas mais comuns são prurido e dor. O aspecto é característico e o exame histopatológico confirma o diagnóstico. Junto com a doença de Bowen e a eritroplasia de Queyrat, é considerada como carcinoma in situ, ou neoplasia intra-epitelial de alto grau (NIAA), a lesão precursora do carcinoma espinocelular (CEC) anal. Sem tratamento, a maioria das lesões permanece benigna e estável. Várias modalidades terapêuticas estão disponíveis, incluindo as medicações tópicas para citodestruição e as técnicas ablativas. Os esquemas tópicos são efetivos. Cabe ao profissional médico escolher a terapia adequada, tendo em mente que a doença é benigna e raramente evolui para carcinoma. Como as recidivas são freqüentes e ainda persistem dúvidas quanto ao potencial de malignização, os doentes devem ser examinados periodicamente para diagnosticar as lesões iniciais.<br>Bowenoid papulosis is an anogenital skin disease characterized by multiple little papules, flat or velvet, which color varies from pink to dark brown. It is provoked by HPV and its transmission is sexual. Most common symptoms are anal pain and itching. Its appearance is characteristic and hystopathological examination confirms diagnosis. Together with Bowen´s disease and Queyrat erythroplasia, is considered as an in situ carcinoma, or high grade intra-epithelial neoplasia (HAIN), a precursor of the squamous-cell carcinoma. Most of lesions remain benign and stable without treatment. There are several kinds of treatment including topical drugs for cytodestruction and ablative techniques. Topic schemes are effectives. The consultant doctor may choose the most adequate therapy, keeping in mind this disease is benign and rarely evolutes to invasive carcinoma. As recurrences are frequent and remain doubts about malign potential, patients must be examined periodically to diagnose initial lesions

Successful knock-in of Hypertrophic Cardiomyopathy-mutation R723G into the MYH7 gene mimics HCM pathology in pigs

Abstract Familial Hypertrophic Cardiomyopathy (HCM) is the most common inherited cardiac disease. About 30% of the patients are heterozygous for mutations in the MYH7 gene encoding the ß-myosin heavy chain (MyHC). Hallmarks of HCM are cardiomyocyte disarray and hypertrophy of the left ventricle, the symptoms range from slight arrhythmias to sudden cardiac death or heart failure. To gain insight into the underlying mechanisms of the diseases’ etiology we aimed to generate genome edited pigs with an HCM-mutation. We used TALEN-mediated genome editing and successfully introduced the HCM-point mutation R723G into the MYH7 gene of porcine fibroblasts and subsequently cloned pigs that were heterozygous for the HCM-mutation R723G. No off-target effects were determined in the R723G-pigs. Surprisingly, the animals died within 24 h post partem, probably due to heart failure as indicated by a shift in the a/ß-MyHC ratio in the left ventricle. Most interestingly, the neonatal pigs displayed features of HCM, including mild myocyte disarray, malformed nuclei, and MYH7-overexpression. The finding of HCM-specific pathology in neonatal R723G-piglets suggests a very early onset of the disease and highlights the importance of novel large animal models for studying causative mechanisms and long-term progression of human cardiac diseases