Ultraviolet absorbing compounds provide a rapid response mechanism for UV protection in some reef fish.

The external mucus surface of reef fish contains ultraviolet absorbing compounds (UVAC), most prominently Mycosporine-like Amino Acids (MAAs). MAAs in the external mucus of reef fish are thought to act as sunscreens by preventing the damaging effects of ultraviolet radiation (UVR), however, direct evidence for their protective role has been missing. We tested the protective function of UVAC's by exposing fish with naturally low, Pomacentrus amboinensis, and high, Thalassoma lunare, mucus absorption properties to a high dose of UVR (UVB: 13.4W∗m(-2), UVA: 6.1W∗m(-2)) and measuring the resulting DNA damage in the form of cyclobutane pyrimidine dimers (CPDs). For both species, the amount of UV induced DNA damage sustained following the exposure to a 1h pulse of high UVR was negatively correlated with mucus absorbance, a proxy for MAA concentration. Furthermore, a rapid and significant increase in UVAC concentration was observed in P. amboinensis following UV exposure, directly after capture and after ten days in captivity. No such increase was observed in T. lunare, which maintained relatively high levels of UV absorbance at all times. P. amboinensis, in contrast to T. lunare, uses UV communication and thus must maintain UV transparent mucus to be able to display its UV patterns. The ability to rapidly alter the transparency of mucus could be an important adaptation in the trade off between protection from harmful UVR and UV communication.CB was funded by a research grant by the SeaWorld Research and Rescue Foundation to UES and CB and a UQ International Fellowship (UQI). UES was funded by the Australian Research Council (DP140100431).This is the author accepted manuscript. The final version is available from Elsevier via http://dx.doi.org/10.1016/j.jphotobiol.2016.04.02

Effect of sotalol on heart rate, QT interval, and atrial fibrillation cycle length in horses with atrial fibrillation

Background: Based on its pharmacokinetic profile and electrophysiological effects in healthy horses, sotalol potentially could be used as a long-term PO antiarrhythmic drug in horses. Objectives: To evaluate the effect of sotalol on heart rate (HR), QT interval, atrial fibrillatory rate, and success of cardioversion in horses with naturally occurring chronic atrial fibrillation (AF). Animals: Twenty-eight horses referred for transvenous electrical cardioversion of AF were treated with 2 mg/kg sotalol PO q12h for 3 days before cardioversion, and 13 horses underwent the same protocol without sotalol administration. Methods: Retrospective study. Before and after sotalol or no treatment, the HR was measured at rest and during an exercise test. The QT interval and atrial fibrillation cycle length (AFCL) were measured at rest using tissue Doppler velocity imaging. Results: In the control group, no significant differences were found between the 2 examinations. In the sotalol group, the HR at rest and during exercise was significantly lower after sotalol treatment, whereas the QT interval and AFCL measured by tissue Doppler increased significantly. Cardioversion to sinus rhythm was achieved in 25/28 horses in the sotalol group and all horses in the control group, but the median number of shocks and energy at cardioversion were significantly lower in the sotalol group. Conclusions and Clinical Importance: In horses with AF, sotalol administration results in class III antiarrhythmic effects and -blocking activity, with moderate HR reduction during exercise

Современные проблемы развития теории функционально устойчивых сложных систем управления

Employment is believed to function as a ‘turning point’ for released offenders. Several theories state that employment can diminish recidivism, and offer different mechanisms to connect employment and crime, such as job stability and job quality. This study examines the effect of employment and employment characteristics on recidivism among Dutch ex-prisoners. Although recidivism risks are high among this group, longitudinal research on the effect of employment on recidivism risks is scarce. We based our analyses on longitudinal data of the Prison Project (n=842) and found that job stability reduces the risk of recidivism. The results indicate that not the guidance to a job, or a high-quality job, but the guidance to stable employment could help to reduce crime rates among this high-risk offender group

Развитие экстремального туризма в Крыму

Целью данной работы является на основе географического анализа факторов становления и особенностей развития экстремального туризма в Крыму разработать рекомендации по усовершенствованию данной отрасли туристской деятельности для создания привлекательного образа Крыма на международной арене

Interview with Grace Reef by Diane Dewhirst

Biographical NoteGrace Reef grew up in Portland, Maine, with her father, Norman Reef, an attorney, and her mother, Patricia Reef. In 1974, as a twelve-year-old, she was the first female Little League baseball player, having sued to integrate girls into the program. She first heard of Senator Mitchell when he ran for governor in 1974. She attended Colby College, graduating in 1983 with a degree in public policy. During college she interned in Mitchell’s Senate office in Washington, D.C.; she worked as a legislative correspondent and was later promoted to be a legislative assistant, eventually becoming one of Mitchell’s senior advisors on children and poverty issues and economic development. She worked for minority leader Tom Daschle after Mitchell retired in 1994, continuing to work on issues of welfare reform and child care. She also worked for Senator Chris Dodd as the minority staff director of the Senate Committee on Health, Education, Labor, and Pensions Subcommittee on Children and Families. She has served as director of intergovernmental affairs for the Children’s Defense Fund. At the time of this interview, she was chief of policy and evaluation for the National Association of Child Care Resource and Referral Agencies (NACCRRA). SummaryInterview includes discussion of: interning in Mitchell’s Senate office; the legislative process; tax reform in the mid-1980s; Mitchell’s decision-making process; the Family Support Act; doing research on child care providers in Maine; child care and development block grants; the Better Child Care Act; the structure of the Senate and the work Mitchell had to do to get legislation passed; Title 4A At Risk Child Care; the compromise on child care vouchers (church-state); Mitchell’s “divide and conquer” approach to dealing with different senators’ doubts and bringing them on board; the Family Medical Leave Act; anecdote of Reef’s presence in the Rose Garden with Mitchell when the Family Medical Leave Act was signed; George H.W. Bush’s saying that they needed a “kinder, gentler nation”; Environment and Public Works Committee work and highway funding; the formula for gas tax returns; miscalculating the formula and watching the bill on the floor of the Senate for three weeks; the National Affordable Housing Act; Mitchell and the Maine delegation; Mitchell’s patience as his greatest attribute; and Mitchell’s sense of humor

Fetal heart rate and fetal heart rate variability in Lipizzaner broodmares

Monitoring fetal heart rate (FHR) and fetal heart rate variability (FHRV) helps to understand and evaluate normal and pathological conditions in the foal. The aim of this study was to establish normal heart rate reference values for the ongoing equine pregnancy and to perform a heart rate variability (HRV) time-domain analysis in Lipizzaner mares. Seventeen middle- and late-term (days 121–333) pregnant Lipizzaner mares were examined using fetomaternal electrocardiography (ECG). The mean FHR (P = 0.004) and the standard deviation of FHR (P = 0.012) significantly decreased during the pregnancy. FHR ± SD values decreased from 115 ± 35 to 79 ± 9 bpm between months 5 and 11. Our data showed that HRV in the foal decreased as the pregnancy progressed, which is in contrast with the findings of earlier equine studies. The standard deviation of normal-normal intervals (SDNN) was higher (70 ± 25 to 166 ± 108 msec) than described previously. The root mean square of successive differences (RMSSD) decreased from 105 ± 69 to 77 ± 37 msec between the 5th and 11th month of gestation. Using telemetric ECG equipment, we could detect equine fetal heartbeat on day 121 for the first time. In addition, the large differences observed in the HR values of four mare-fetus pairs in four consecutive months support the assumption that there might be ‘high-HR’ and ‘low-HR’ fetuses in horses. It can be concluded that the analysis of FHR and FHRV is a promising tool for the assessment of fetal well-being but the applicability of these parameters in the clinical setting and in studs requires further investigation

Alien Registration- Reef, Sam (Portland, Cumberland County)

https://digitalmaine.com/alien_docs/31963/thumbnail.jp

Global coastal wetland change under sea-level rise and related stresses: The DIVA Wetland Change Model

The Dynamic Interactive Vulnerability Assessment Wetland Change Model (DIVA_WCM) comprises a dataset of contemporary global coastal wetland stocks (estimated at 756 × 10^3 km^2 (in 2011)), mapped to a one-dimensional global database, and a model of the macro-scale controls on wetland response to sea-level rise. Three key drivers of wetland response to sea-level rise are considered: 1) rate of sea-level rise relative to tidal range; 2) lateral accommodation space; and 3) sediment supply. The model is tuned by expert knowledge, parameterised with quantitative data where possible, and validated against mapping associated with two large-scale mangrove and saltmarsh vulnerability studies. It is applied across 12,148 coastal segments (mean length 85 km) to the year 2100. The model provides better-informed macro-scale projections of likely patterns of future coastal wetland losses across a range of sea-level rise scenarios and varying assumptions about the construction of coastal dikes to prevent sea flooding (as dikes limit lateral accommodation space and cause coastal squeeze). With 50 cm of sea-level rise by 2100, the model predicts a loss of 46–59% of global coastal wetland stocks. A global coastal wetland loss of 78% is estimated under high sea-level rise (110 cm by 2100) accompanied by maximum dike construction. The primary driver for high vulnerability of coastal wetlands to sea-level rise is coastal squeeze, a consequence of long-term coastal protection strategies. Under low sea-level rise (29 cm by 2100) losses do not exceed ca. 50% of the total stock, even for the same adverse dike construction assumptions. The model results confirm that the widespread paradigm that wetlands subject to a micro-tidal regime are likely to be more vulnerable to loss than macro-tidal environments. Countering these potential losses will require both climate mitigation (a global response) to minimise sea-level rise and maximisation of accommodation space and sediment supply (a regional response) on low-lying coasts.The authors gratefully acknowledge funding from the European Union under contract number EVK2-2000-22024. They thank all their partners in the DINAS-COAST project Dynamic and Interactive Assessment of National, Regional and Global Vulnerability of Coastal Zones to Climate Change and Sea-level rise. We are grateful to staff at UNEP-WCMC for generous access to evolving databases on global coastal wetland extent: Jon Hutton, Hannah Thomas, Jan-Willem van Bochove, Simon Blyth and Chris McOwen. Current wetland databases held at WCMC build upon the pioneering efforts of Mark Spalding and Carmen Lacambra.This is the author accepted manuscript. The final version is available from Elsevier via http://dx.doi.org/10.1016/j.gloplacha.2015.12.01