A web-based tool for teaching pharmacy practice competency

Aims to implement and assess the effectiveness of the Strathclyde Computerized Randomized Interactive Prescription Tutor (SCRIPT) in teaching a competency-based undergraduate pharmacy course. Data on students' access to SCRIPT, collected by quantitative electronic data capture, were analyzed to determine student usage patterns and correlations between usage and grades in class assessments. Data on students' perceptions were collected by electronic questionnaire and semistructured interviews. Teaching staff members also were interviewed. Two hundred forty-three students accessed SCRIPT a median of 23 times each. Students accessed SCRIPT predominantly at times outside normal teaching hours and tended to access the tool more often in the 48 hours preceding class assessments. Feedback from students indicated overall satisfaction with the tool to compliment the timetabled teaching sessions but highlighted that more specific feedback on the examples was required. All staff comments were positive. Students and teaching staff members valued SCRIPT as a tool to compliment teaching of the competency-based pharmacy practice classes in the MPharm degree

Computer Algebra Solving of Second Order ODEs Using Symmetry Methods

An update of the ODEtools Maple package, for the analytical solving of 1st and 2nd order ODEs using Lie group symmetry methods, is presented. The set of routines includes an ODE-solver and user-level commands realizing most of the relevant steps of the symmetry scheme. The package also includes commands for testing the returned results, and for classifying 1st and 2nd order ODEs.Comment: 24 pages, LaTeX, Soft-package (On-Line help) and sample MapleV sessions available at: http://dft.if.uerj.br/odetools.htm or http://lie.uwaterloo.ca/odetools.ht

A Stochastic Approach to Shortcut Bridging in Programmable Matter

In a self-organizing particle system, an abstraction of programmable matter, simple computational elements called particles with limited memory and communication self-organize to solve system-wide problems of movement, coordination, and configuration. In this paper, we consider a stochastic, distributed, local, asynchronous algorithm for "shortcut bridging", in which particles self-assemble bridges over gaps that simultaneously balance minimizing the length and cost of the bridge. Army ants of the genus Eciton have been observed exhibiting a similar behavior in their foraging trails, dynamically adjusting their bridges to satisfy an efficiency trade-off using local interactions. Using techniques from Markov chain analysis, we rigorously analyze our algorithm, show it achieves a near-optimal balance between the competing factors of path length and bridge cost, and prove that it exhibits a dependence on the angle of the gap being "shortcut" similar to that of the ant bridges. We also present simulation results that qualitatively compare our algorithm with the army ant bridging behavior. Our work gives a plausible explanation of how convergence to globally optimal configurations can be achieved via local interactions by simple organisms (e.g., ants) with some limited computational power and access to random bits. The proposed algorithm also demonstrates the robustness of the stochastic approach to algorithms for programmable matter, as it is a surprisingly simple extension of our previous stochastic algorithm for compression.Comment: Published in Proc. of DNA23: DNA Computing and Molecular Programming - 23rd International Conference, 2017. An updated journal version will appear in the DNA23 Special Issue of Natural Computin

Adverse Events among HIV/MDR-TB Co-Infected Patients Receiving Antiretroviral and Second Line Anti-TB Treatment in Mumbai, India.

Significant adverse events (AE) have been reported in patients receiving medications for multidrug- and extensively-drug-resistant tuberculosis (MDR-TB & XDR-TB). However, there is little prospective data on AE in MDR- or XDR-TB/HIV co-infected patients on antituberculosis and antiretroviral therapy (ART) in programmatic settings

The Dwarf Spheroidal Companions to M31: Variable Stars in Andromeda VI

We have surveyed Andromeda VI, a dwarf spheroidal galaxy companion to M31, for variable stars using F450W and F555W observations obtained with the Hubble Space Telescope. A total of 118 variables were found, with 111 being RR Lyrae, 6 anomalous Cepheids, and 1 variable we were unable to classify. We find that the Andromeda VI anomalous Cepheids have properties consistent with those of anomalous Cepheids in other dwarf spheroidal galaxies. We revise the existing period-luminosity relations for these variables. Further, using these and other available data, we show that there is no clear difference between fundamental and first-overtone anomalous Cepheids in a period-amplitude diagram at shorter periods, unlike the RR Lyrae. For the Andromeda VI RR Lyrae, we find that they lie close to the Oosterhoff type I Galactic globular clusters in the period-amplitude diagram, although the mean period of the RRab stars, = 0.588 d, is slightly longer than the typical Oosterhoff type I cluster. The mean V magnitude of the RR Lyrae in Andromeda VI is 25.29+/-0.03, resulting in a distance 815+/-25 kpc on the Lee, Demarque, & Zinn distance scale. This is consistent with the distance derived from the I magnitude of the tip of the red giant branch. Similarly, the properties of the RR Lyrae indicate a mean abundance for Andromeda VI which is consistent with that derived from the mean red giant branch color.Comment: 23 pages, including 13 figures and 6 tables, emulateapj5/apjfonts style. Accepted by the Astronomical Journal. We recommend the interested reader to download the preprint with full-resolution figures, which can be found at http://www.noao.edu/noao/staff/pritzl/M31dwarfs.htm

Modelling non-linear redshift-space distortions in the galaxy clustering pattern: systematic errors on the growth rate parameter

We investigate the ability of state-of-the-art redshift-space distortions models for the galaxy anisotropic two-point correlation function \xi(r_p, \pi), to recover precise and unbiased estimates of the linear growth rate of structure f, when applied to catalogues of galaxies characterised by a realistic bias relation. To this aim, we make use of a set of simulated catalogues at z = 0.1 and z = 1 with different luminosity thresholds, obtained by populating dark-matter haloes from a large N-body simulation using halo occupation prescriptions. We examine the most recent developments in redshift-space distortions modelling, which account for non-linearities on both small and intermediate scales produced respectively by randomised motions in virialised structures and non-linear coupling between the density and velocity fields. We consider the possibility of including the linear component of galaxy bias as a free parameter and directly estimate the growth rate of structure f. Results are compared to those obtained using the standard dispersion model, over different ranges of scales.We find that the model of Taruya et al. (2010), the most sophisticated one considered in this analysis, provides in general the most unbiased estimates of the growth rate of structure, with systematic errors within 4% over a wide range of galaxy populations spanning luminosities between L > L* and L > 3L*. The scale-dependence of galaxy bias plays a role on recovering unbiased estimates of f when fitting quasi non-linear scales. Its effect is particularly severe for most luminous galaxies, for which systematic effects in the modelling might be more difficult to mitigate and have to be further investigated. [...]Comment: 17 pages, 16 figures, Accepted for publication in MNRA

ESO Imaging Survey. The Stellar Catalogue in the Chandra Deep Field South

(abridged) Stellar catalogues in five passbands (UBVRI) over an area of approximately 0.3 deg^2, comprising about 1200 objects, and in seven passbands (UBVRIJK) over approximately 0.1 deg^2, comprising about 400 objects, in the direction of the Chandra Deep Field South are presented. The 90% completeness level of the number counts is reached at approximately U = 23.8, B = 24.0, V = 23.5, R = 23.0, I = 21.0, J = 20.5, K = 19.0. A scheme is presented to select point sources from these catalogues, by combining the SExtractor parameter CLASS_STAR from all available passbands. Probable QSOs and unresolved galaxies are identified by using the previously developed \chi^2-technique (Hatziminaoglou et al 2002), that fits the overall spectral energy distributions to template spectra and determines the best fitting template. The observed number counts, colour-magnitude diagrams, colour-colour diagrams and colour distributions are presented and, to judge the quality of the data, compared to simulations based on the predictions of a Galactic Model convolved with the estimated completeness functions and the error model used to describe the photometric errors of the data. The resulting stellar catalogues and the objects identified as likely QSOs and unresolved galaxies with coordinates, observed magnitudes with errors and assigned spectral types by the $\chi^2$-technique are presented and are publicly available.Comment: Paper as it will appear in print. Complete figures and tables can be obtained from: http://www.eso.org/science/eis/eis_pub/eis_pub.html. Astronomy & Astrophysics, accepted for publicatio

The Hubble Space Telescope Treasury Program on the Orion Nebula Cluster

The Hubble Space Telescope (HST) Treasury Program on the Orion Nebula Cluster has used 104 orbits of HST time to image the Great Orion Nebula region with the Advanced Camera for Surveys (ACS), the Wide-Field/Planetary Camera 2 (WFPC2) and the Near Infrared Camera and Multi Object Spectrograph (NICMOS) instruments in 11 filters ranging from the U-band to the H-band equivalent of HST. The program has been intended to perform the definitive study of the stellar component of the ONC at visible wavelengths, addressing key questions like the cluster IMF, age spread, mass accretion, binarity and cirumstellar disk evolution. The scanning pattern allowed to cover a contiguous field of approximately 600 square arcminutes with both ACS and WFPC2, with a typical exposure time of approximately 11 minutes per ACS filter, corresponding to a point source depth AB(F435W) = 25.8 and AB(F775W)=25.2 with 0.2 magnitudes of photometric error. We describe the observations, data reduction and data products, including images, source catalogs and tools for quick look preview. In particular, we provide ACS photometry for 3399 stars, most of them detected at multiple epochs, WFPC2 photometry for 1643 stars, 1021 of them detected in the U-band, and NICMOS JH photometry for 2116 stars. We summarize the early science results that have been presented in a number of papers. The final set of images and the photometric catalogs are publicly available through the archive as High Level Science Products at the STScI Multimission Archive hosted by the Space Telescope Science Institute.Comment: Accepted for publication on the Astrophysical Journal Supplement Series, March 27, 201

Evaluating the potential for the environmentally sustainable control of foot and mouth disease in Sub-Saharan Africa

Strategies to control transboundary diseases have in the past generated unintended negative consequences for both the environment and local human populations. Integrating perspectives from across disciplines, including livestock, veterinary and conservation sectors, is necessary for identifying disease control strategies that optimise environmental goods and services at the wildlife-livestock interface. Prompted by the recent development of a global strategy for the control and elimination of foot-and-mouth disease (FMD), this paper seeks insight into the consequences of, and rational options for potential FMD control measures in relation to environmental, conservation and human poverty considerations in Africa. We suggest a more environmentally nuanced process of FMD control that safe-guards the integrity of wild populations and the ecosystem dynamics on which human livelihoods depend while simultaneously improving socio-economic conditions of rural people. In particular, we outline five major issues that need to be considered: 1) improved understanding of the different FMD viral strains and how they circulate between domestic and wildlife populations; 2) an appreciation for the economic value of wildlife for many African countries whose presence might preclude the country from ever achieving an FMD-free status; 3) exploring ways in which livestock production can be improved without compromising wildlife such as implementing commodity-based trading schemes; 4) introducing a participatory approach involving local farmers and the national veterinary services in the control of FMD; and 5) finally the possibility that transfrontier conservation might offer new hope of integrating decision-making at the wildlife-livestock interface

Three-pion exchange: a gap in the nucleon-nucleon potential

The leading contribution to the three-pion exchange nucleon-nucleon potential is calculated in the framework of chiral symmetry. It has pseudoscalar and axial components and is dominated by the former, which has a range of about 1.5 fm and tends to enhance the OPEP. The strength of this force does not depend on the pion mass and hence it survives in the chiral limit.Comment: 20 pages, 5 figures, 1 tabl