Pathogenesis of Secondary Anemia

In patients with tissue damage of a malignant, infectious, inflammatory, ischemic or surgical nature, the plasma elimination (PE) of folates, iron, albumin, and cholesterol appears to be increased. Not all substances have been studied in diagnostic groups

A Fresh Look At The Equal Credit Opportunity Act

The subsequent material will illustrate that despite the fact that women have been required to meet both a different and a higher standard for them to be deemed creditworthy, studies have shown that they (especially single women) are in fact better credit risks than men. Nevertheless, in an investigation of special problems concerning the availability of credit, the National Commission on Consumer Finance identified difficulties that women in particular faced in obtaining consumer, as well as mortgage, credit

Invariants of multidimensional time series based on their iterated-integral signature

We introduce a novel class of features for multidimensional time series, that are invariant with respect to transformations of the ambient space. The general linear group, the group of rotations and the group of permutations of the axes are considered. The starting point for their construction is Chen's iterated-integral signature.Comment: complete rewrite of Section 3.

The relationship between the systemic inflammatory response, tumour proliferative activity, T-lymphocytic and macrophage infiltration, microvessel density and survival in patients with primary operable breast cancer

The significance of the inter-relationship between tumour and host local/systemic inflammatory responses in primary operable invasive breast cancer is limited. The inter-relationship between the systemic inflammatory response (pre-operative white cell count, C-reactive protein and albumin concentrations), standard clinicopathological factors, tumour T-lymphocytic (CD4+ and CD8+) and macrophage (CD68+) infiltration, proliferative (Ki-67) index and microvessel density (CD34+) was examined using immunohistochemistry and slide-counting techniques, and their prognostic values were examined in 168 patients with potentially curative resection of early-stage invasive breast cancer. Increased tumour grade and proliferative activity were associated with greater tumour T-lymphocyte (P<0.05) and macrophage (P<0.05) infiltration and microvessel density (P<0.01). The median follow-up of survivors was 72 months. During this period, 31 patients died; 18 died of their cancer. On univariate analysis, increased lymph-node involvement (P<0.01), negative hormonal receptor (P<0.10), lower albumin concentrations (P<0.01), increased tumour proliferation (P<0.05), increased tumour microvessel density (P<0.05), the extent of locoregional control (P<0.0001) and limited systemic treatment (Pless than or equal to0.01) were associated with cancer-specific survival. On multivariate analysis of these significant covariates, albumin (HR 4.77, 95% CI 1.35–16.85, P=0.015), locoregional treatment (HR 3.64, 95% CI 1.04–12.72, P=0.043) and systemic treatment (HR 2.29, 95% CI 1.23–4.27, P=0.009) were significant independent predictors of cancer-specific survival. Among tumour-based inflammatory factors, only tumour microvessel density (P<0.05) was independently associated with poorer cancer-specific survival. The host inflammatory responses are closely associated with poor tumour differentiation, proliferation and malignant disease progression in breast cancer

The Lost Mysteries of New Orleans

A collection of German-language literary texts from the mid-1850s to the mid-1860s by Baron Ludwig von Reizenstein, translated by Steven W. RowanOrientation on the author, Baron Ludwig von Reizenstein, pp. 1-4. “New Orleans Whisker Stories,” a fictional narrative of an encounter with a Bluebeard, published but not completed in 1855, pp. 5-30. “The Devil in New Orleans,” published but not completed, 1861, pp. 31-53. An adaptation of a literary work from Spanish and French sources portraying an encounter with Satan in New Orleans at the start of the Civil War, giving a scathing account of the mood of the city of New Orleans in that period. “Bonseigneur in New Orleans,” published but not completed, 1865, pp. 54-178, an elaborate work divided into two parts, the first a narrative (pp. 54-111) on the siege and capture of New Orleans by Federal forces in 1862, linked with a longer narrative (pp. 112-178) on a fictional Creole New Orleans family, the Bonseigneurs, who supposedly played a major role in the establishment of slave plantations in Louisiana and throughout the Caribbean through 1861. It ends abruptly in Guadeloupe in the midst of a Black uprising which many Whites seem to support