Interplanetary Consequences of a Large CME

We analyze a coronal mass ejection (CME) which resulted from an intense flare in active region AR486 on November 4, 2003. The CME propagation and speed are studied with interplanetary scintillation images, near-Earth space mission data, and Ulysses measurements. Together, these diverse diagnostics suggest that the internal magnetic energy of the CME determines its interplanetary consequences.Comment: 5 pages, 9 figures, To appear in "Magnetic Coupling between the Interior and the Atmosphere of the Sun", eds. S.S. Hasan and R.J. Rutten, Astrophysics and Space Science Proceedings, Springer-Verlag, Heidelberg, Berlin, 200

Design and Evaluation of Heterobivalent PAR1–PAR2 Ligands as Antagonists of Calcium Mobilization

A novel class of bivalent ligands targeting putative protease-activated receptor (PAR) heteromers has been prepared based upon reported antagonists for the subtypes PAR1 and PAR2. Modified versions of the PAR1 antagonist RWJ-58259 containing alkyne adapters were connected via cycloaddition reactions to azide-capped polyethylene glycol (PEG) spacers attached to imidazopyridazine-based PAR2 antagonists. Initial studies of the PAR1–PAR2 antagonists indicated that they inhibited G alpha q-mediated calcium mobilization in endothelial and cancer cells driven by both PAR1 and PAR2 agonists. Compounds of this novel class hold promise for the prevention of restenosis, cancer cell metastasis, and other proliferative disorders

Trends in salmonella enteric serovar typhi in Nairobi, Kenya from 2004 to 2006

Background: Typhoid fever is a global health problem. The World Health Organization (WHO) estimates that the current annual global burden of typhoid is approximately 22 million new cases, 5% of which are fatal. Methodology: To assess the trends in antibiotic resistance in 100 Salmonella enterica serovar Typhi strains were isolated from the blood of patients in Nairobi, Kenya, from 2004 to 2006. All isolates were tested against ampicilin, chloramphenic, nalidixic acid, ciprofloxacin, cotrimoxazole, cefuroxime, cefriaxone, amoxycillin/clavulanic acid, tetracycline and gentamycin. Susceptibility and resistance were determined using MIC and disk diffusion tests. Results: From 2004 to 2006 a total of 100 strains were studied; 70% of the isolates were multidrug resistant (MDR) while 15% of the isolates were sensitive to all drugs tested. Of 13 isolates that were resistant to ciprofloxacin and nalidixic acid by disk diffusion, 11 had an MIC of 0. 25 μg/ml while two isolates had an MIC of 1.00 μg,/ml. Resistance in ampicillin decreased from 88% in 2004 to 64% in 2005; this increased to 76% in 2006. Similar trends were observed for four other antibiotics tested. Conclusion: The prescription of first-line antibiotics used in the treatment of S. Typhi should be stopped temporarily. Drugs such as cipfloxacin would be useful in the treatment of typhoid caused by MDR S. Typhi. There is need to monitor the resistance in flouroquinolones as resistance to these drugs has been observed and they are the current drugs used to treat typhoid

Charity of Patinenkil Kanakku Nulkal

Voluntary help is the charity. Only by adding material. The doesn’t mean you have to help. The big charity is the one who uses what he does not need for his life and gives the rest to others. Eleven accounts best illustrate this equivalence of giving to the other side of receipt. But in our lives, we adhere to giving as soon as we receive something. the best quality is to give in advance to other as you would to point out what is being done in this world is for the hereafter our ancestors considered it unethical to expect that. Compassion makes a gift realizes that Mallam. In this world we are the glory off the charity that lasts after death

Network of Earthquakes and Recurrences Therein

We quantify the correlation between earthquakes and use the same to distinguish between relevant causally connected earthquakes. Our correlation metric is a variation on the one introduced by Baiesi and Paczuski (2004). A network of earthquakes is constructed, which is time ordered and with links between the more correlated ones. Data pertaining to the California region has been used in the study. Recurrences to earthquakes are identified employing correlation thresholds to demarcate the most meaningful ones in each cluster. The distribution of recurrence lengths and recurrence times are analyzed subsequently to extract information about the complex dynamics. We find that the unimodal feature of recurrence lengths helps to associate typical rupture lengths with different magnitude earthquakes. The out-degree of the network shows a hub structure rooted on the large magnitude earthquakes. In-degree distribution is seen to be dependent on the density of events in the neighborhood. Power laws are also obtained with recurrence time distribution agreeing with the Omori law.Comment: 17 pages, 5 figure

The Detour Domination and Connected Detour Domination values of a graph

The number of -sets that  belongs to in G is defined as the detour domination value of indicated by for each vertex . In this article, we examined at the concept of a graph’s detour domination value. The connected detour domination values of a vertex  represented as  , are defined as the number of -sets to which a vertex belongs  to G. Some of the related detour dominating values in graphs’ general characteristics are examined. This concept’s satisfaction of some general properties is investigated. Some common graphs are established

An Innovative Hybrid Approach for Predicting Crop Yields across Diverse States and Crops

The use of machine learning and deep learning may help estimate crops by automatically extracting attributes and learning from information. Meanwhile, smart farming technology aids farmers in increasing yields by isolating key factors in plant development. In this study, we present a unique hybrid approach (SLR) for predicting crops by extracting key characteristics from SVM (Support Vector Machine), LSTM (Long-Short Term Memory), or RNN (Recurrent Neural Network).  Here, we experimented with crops from a variety of states to estimate their potential yields in quintals per hectare. The suggested method has a37.45 percent precision rate, an 80.00 percent recall rate, a51.01 percent fscore, a93.64 percent specificity rate, and an accuracy rate of 93.02 percent

ANTIUROLITHIATIC ACTIVITY OF ETHANOLIC EXTRACT OF EICHHORNIA CRASSIPES (MART.) SOLMS WHOLE PLANT ON ETHYLENE GLYCOL-INDUCED UROLITHIASIS IN WISTAR RATS

Objective: In India Indigenous system of medicine, the plant Eichhornia crassipes (Mart.) Solms is claimed to be useful for different ailments. The purpose of this study is to investigate the significant activity of the ethanolic extract of E. crassipes (Mart.) Solms whole plant in the treatment of renal stone by ethylene glycol (EG)-induced urolithiasis in Wistar rats. Methods: Wistar rat will be divided into four groups. All the animals received EG 0.75%v/v by orally for 28 days. Group I was received 0.75%v/v EG for 28 days. Groups II, III, and IV were received cystone, ethanolic extract of E. crassipes (Mart.) Solms (200 mg/kg, and 400 mg/kg), respectively, administered orally from 15th to 28th day for curative regimen. Animals were housed in metabolic cages and collect the 24 h urine samples and serum samples on the 7th, 14th, 21th, and 28th day of the experiments. Under the microscopical study to observe the crystals in urine sample. The biochemical parameters monitored in the present study are calcium, oxalate, magnesium, phosphorus, urea, creatinine, uric acid, blood urea nitrogen (BUN), and lactate dehydrogenase (LDH) in urine and serum samples. Results: The EG feeding resulted in elevated renal excretion of calcium, phosphate, oxalate, and decreased renal excretion of magnesium as well-elevated serum BUN, creatinine, uric acid, urea, LDH levels, and decreased the urine pH and urine volume. Treatment of the ethanolic extract of E. crassipes (Mart.) Solms significantly reduced the elevated calcium, phosphate, oxalate in urine as well as BUN, creatinine, uric acid, urea, and LDH level in serum. It also restores the normal urine pH and promotes the urine output. Conclusion: Ethanolic extract of E. crassipes (Mart.) Solms exhibited significant anti-urolithiatic activity evident from urine calcium, phosphate, oxalate levels and serum BUN, creatinine, uric acid, urea and LDH levels

Aquatic Organisms in Nattrinai

There are many kinds of organisms living in different environments in the world. They had a physique according to the environment in which they lived and had food habits for their respective environments. Just as on land, there are living creatures in the water. In the Sangam age, there were more species living in Sangam age than in today's time. They have been studied very carefully by the Sangam scholars and expressed through their songs. Thus, one of the Sangam texts, Natrinai, describes the life of the ancient Tamils who lived in harmony with nature. In the book, there are five types of land mentioned: Kurinji, Mullai, Marudham, Neithal, and Paalai. The five lands have water bodies in the names of spring, waterfall, wild river, lake, pond, small pond, reservoir, the mouth of a river, pit, well, and trough. Marutham land is a well-watered area with water bodies such as Natural Pond and Pond, and adjoining fields and muddy areas mixed with water and land. They are called the freshwater area. Therefore, the species that live there are called freshwater living organisms. The saline water found in the Neithal Land is called brackish water. These areas are composed of water bodies such as the sea, coastal sands, and lagoons. The organisms that live there are called brackish water organisms. Thus, there are many aquatic organisms in Natrinai. Among them are freshwater fishes such as swordfish, butterfish, catfish, brackish water fish such as sharks, fish that live in both fresh and brackish water bodies such as mackerel, horse fish, and prawns, and fish that live in both water bodies. This article explores and explains species such as crocodiles and crabs