1,823 research outputs found

    The significance of vehicle technology and driver behaviour in determining road vehicle exhaust emission rates

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    PhD ThesisThis research utilises data from instrumented vehicles and road side remote sensing in an urban environment to explore the relationships between exhaust tail pipe emissions, vehicle technology, and driver behaviour. An investigation is carried out into the nature of variability that exists in the driving behaviour of a sample of drivers, and the influence of such variability on fuel consumption and the emission rates of exhaust pollutants. Analysis of data from remote sensing reveals that emissions from petrol cars (CO, HC, NO, PM) are all observed to display a statistically significant reduction with the introduction of each successive Euro emissions standard from Euro 1 onwards. However, Euro 2 diesel cars are observed to emit statistically higher rates of NO than either Euro 1 or Euro 3 standard diesel cars. When the New European Driving Cycle is synthesised from remote sensing data and compared with type approval data published by the UK Vehicle Certification Agency, mean CO emissions from petrol cars ≤3 years old measured using remote sensing are found to be 1.3 times higher than published original type approval test values; this factor increases to 2.2 for cars 4 – 8 years old, and 6.4 for cars 9 – 12 years old. The corresponding factors for diesel cars are 1.1, 1.4, and 1.2 respectively. This thesis has made an original contribution to the field in two main areas; firstly by quantifying the ‘real-world’ emission rates for a sample of the UK vehicle fleet in an urban area, and demonstrating the statistically significant differences in emission rates between groups of vehicles; and secondly, by proposing a feasible method to move towards reconciling essentially instantaneous road side measurements of exhaust emissions obtained from remote sensing, with laboratory based measurements taken over a legislated driving cycle as part of the new vehicle type approval process.EPSRC FUTURES Project

    Toward reconciling instantaneous roadside measurements of Light Duty Vehicle exhaust emissions with type approval driving cycles

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    A method is proposed to relate essentially instantaneous roadside measurements of vehicle exhaust emissions, with emission results generated over a type approval driving cycle. An urban remote sensing data set collected in 2008 is used to define the dynamic relationship between vehicle specific power and exhaust emissions, across a range of vehicle ages, engine capacities, and fuel types. The New European Driving Cycle is synthesized from the remote sensing data using vehicle specific power to characterize engine load, and the results compared with official published emissions data from vehicle type approval tests over the same driving cycle. Mean carbon monoxide emissions from gasoline-powered cars ≤3 years old measured using remote sensing are found to be 1.3 times higher than published original type approval test values; this factor increases to 2.2 for cars 4-8 years old, and 6.4 for cars 9-12 years old. The corresponding factors for diesel cars are 1.1, 1.4, and 1.2, respectively. Results for nitric oxide, hydrocarbons, and particulate matter are also reported. The findings have potential implications for the design of traffic management interventions aimed at reducing emissions, fleet inspection and maintenance programs, and the specification of vehicle emission models

    Perceptions of Mask Use During the COVID-19 Pandemic

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    The CDC recommends covering of the face and nose during the COVID-19 pandemic as a primary mitigation strategy for viral transmission. Masks minimize the number of viral particles emitted by the wearer; mask use serves to reduce the effects on population transmission. Mask wearing behaviors have been shown to vary across different groups like gender identity, however, differences between people with and without lung disease have yet to be explored. Goal: Examine perceptions, attitudes, and behaviors related to mask use during the COVID-19 pandemic of those with and without lung disease nationally.https://scholarworks.uvm.edu/comphp_gallery/1307/thumbnail.jp

    Simple Process-Led Algorithms for Simulating Habitats (SPLASH v.1.0): Robust Indices of Radiation, Evapotranspiration and Plant-Available Moisture

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    Bioclimatic indices for use in studies of ecosystem function, species distribution, and vegetation dynamics under changing climate scenarios depend on estimates of surface fluxes and other quantities, such as radiation, evapotranspi- ration and soil moisture, for which direct observations are sparse. These quantities can be derived indirectly from me- teorological variables, such as near-surface air temperature, precipitation and cloudiness. Here we present a consolidated set of simple process-led algorithms for simulating habitats (SPLASH) allowing robust approximations of key quantities at ecologically relevant timescales. We specify equations, derivations, simplifications, and assumptions for the estima- tion of daily and monthly quantities of top-of-the-atmosphere solar radiation, net surface radiation, photosynthetic photon flux density, evapotranspiration (potential, equilibrium, and actual), condensation, soil moisture, and runoff, based on analysis of their relationship to fundamental climatic drivers. The climatic drivers include a minimum of three meteoro- logical inputs: precipitation, air temperature, and fraction of bright sunshine hours. Indices, such as the moisture index, the climatic water deficit, and the Priestley–Taylor coeffi- cient, are also defined. The SPLASH code is transcribed in C++, FORTRAN, Python, and R. A total of 1 year of results are presented at the local and global scales to exemplify the spatiotemporal patterns of daily and monthly model outputs along with comparisons to other model results

    Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

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    A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements

    Climate Action to transform Food Systems - Linking the UN Food Systems Summit and COP26 through initiatives that support greater resilience to climate change

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    The climate crisis is a major threat to our food systems, undermining decades of progress in providing more nutritious diets to a growing global population. Two key events take place in 2021 – the United Nations Food Systems Summit (UNFSS) and the 26th session of the Conference of the Parties (COP26) to the United Nations Framework Convention on Climate Change (UNFCCC). Both events could produce mutually reinforcing commitments and action at the intersection of climate and food challenges. Although these conferences are highly aligned in terms of their goals, they are not systematically feed intoing each other in a way that reinforces and amplifies their shared ambitions. This paper looks at how food systems transformation is an essential aspect of climate action - and sets out how to align climate action with efforts to promote more sustainable food systems. The revision of Nationally Determined Contributions (NDC)s in preparation of COP26 offers a unique opportunity to set targets and initiatives that reduce the impact of unsustainable food systems on the global climate – and at the same time helps the agricultural and food sectors become more resilient to the impacts of climate change. At the intersection between food systems transformation and climate action, a number of emerging and established Climate Risk Reduction and Management (CRRM) initiatives enable contributions to reduce risks in food systems that are aggravated and compounded by climate change – and protect the livelihoods of those who depend on these food systems. This paper outlines how such initiatives offer vulnerable countries a broad pool of knowledge and tools to couple objectives of climate action and food systems transformation, and opportunities for global collaboration and engagement to develop NDCs that tackle both the climate and the food challenge we face in a mutually reinforcing way

    Simple process-led algorithms for simulating habitats (SPLASH v.1.0): Robust indices of radiation, evapotranspiration and plant-available moisture

    Get PDF
    Bioclimatic indices for use in studies of ecosystem function, species distribution, and vegetation dynamics under changing climate scenarios depend on estimates of surface fluxes and other quantities, such as radiation, evapotranspiration and soil moisture, for which direct observations are sparse. These quantities can be derived indirectly from meteorological variables, such as near-surface air temperature, precipitation and cloudiness. Here we present a consolidated set of simple process-led algorithms for simulating habitats (SPLASH) allowing robust approximations of key quantities at ecologically relevant timescales. We specify equations, derivations, simplifications, and assumptions for the estimation of daily and monthly quantities of top-of-the-atmosphere solar radiation, net surface radiation, photosynthetic photon flux density, evapotranspiration (potential, equilibrium, and actual), condensation, soil moisture, and runoff, based on analysis of their relationship to fundamental climatic drivers. The climatic drivers include a minimum of three meteorological inputs: precipitation, air temperature, and fraction of bright sunshine hours. Indices, such as the moisture index, the climatic water deficit, and the Priestley–Taylor coefficient, are also defined. The SPLASH code is transcribed in C++, FORTRAN, Python, and R. A total of 1 year of results are presented at the local and global scales to exemplify the spatiotemporal patterns of daily and monthly model outputs along with comparisons to other model results

    Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia.

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    Non-genetic drug resistance is increasingly recognised in various cancers. Molecular insights into this process are lacking and it is unknown whether stable non-genetic resistance can be overcome. Using single cell RNA-sequencing of paired drug naïve and resistant AML patient samples and cellular barcoding in a unique mouse model of non-genetic resistance, here we demonstrate that transcriptional plasticity drives stable epigenetic resistance. With a CRISPR-Cas9 screen we identify regulators of enhancer function as important modulators of the resistant cell state. We show that inhibition of Lsd1 (Kdm1a) is able to overcome stable epigenetic resistance by facilitating the binding of the pioneer factor, Pu.1 and cofactor, Irf8, to nucleate new enhancers that regulate the expression of key survival genes. This enhancer switching results in the re-distribution of transcriptional co-activators, including Brd4, and provides the opportunity to disable their activity and overcome epigenetic resistance. Together these findings highlight key principles to help counteract non-genetic drug resistance

    Search for top squark pair production using dilepton final states in pp collision data collected at root s=13TeV

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    A search is presented for supersymmetric partners of the top quark (top squarks) in final states with two oppositely charged leptons (electrons or muons), jets identified as originating from bquarks, and missing transverse momentum. The search uses data from proton-proton collisions at root s = 13 TeV collected with the CMS detector, corresponding to an integrated luminosity of 137 fb(-1). Hypothetical signal events are efficiently separated from the dominant top quark pair production background with requirements on the significance of the missing transverse momentum and on transverse mass variables. No significant deviation is observed from the expected background. Exclusion limits are set in the context of simplified supersymmetric models with pair-produced lightest top squarks. For top squarks decaying exclusively to a top quark and a lightest neutralino, lower limits are placed at 95% confidence level on the masses of the top squark and the neutralino up to 925 and 450 GeV, respectively. If the decay proceeds via an intermediate chargino, the corresponding lower limits on the mass of the lightest top squark are set up to 850 GeV for neutralino masses below 420 GeV. For top squarks undergoing a cascade decay through charginos and sleptons, the mass limits reach up to 1.4 TeV and 900 GeV respectively for the top squark and the lightest neutralino.Peer reviewe

    Measurement of the t(t)over-barb(b)over-bar production cross section in the all-jet final state in pp collisions at root s=13 TeV

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    A measurement of the production cross section of top quark pairs in association with two b jets (t (t) over barb (b) over bar) is presented using data collected in proton-proton collisions at root s=13 TeV by the CMS detector at the LHC corresponding to an integrated luminosity of 35.9 fb(-1). The cross section is measured in the all-jet decay channel of the top quark pair by selecting events containing at least eight jets, of which at least two are identified as originating from the hadronization of b quarks. A combination of multivariate analysis techniques is used to reduce the large background from multijet events not containing a top quark pair, and to help discriminate between jets originating from top quark decays and other additional jets. The cross section is determined for the total phase space to be 5.5 +/- 0.3 (stat)(-1.3)(+)(1.6) (syst)pb and also measured for two fiducial t (t) over barb (b) over bar, definitions. The measured cross sections are found to be larger than theoretical predictions by a factor of 1.5-2.4, corresponding to 1-2 standard deviations. (C) 2020 The Author. Published by Elsevier B.V.Peer reviewe
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