Core-periphery analysis: a tale of two nations

Bias, unreliability and omission have been documented in traditional sources of trade data; the lack of service data in trade statistics is the most frequently cited shortcoming. Current trade liberalization is likely to exacerbate these deficiencies. This paper develops and applies a location quotient based methodology for analysing core-periphery dualism, thus obviating the use of trade data. Our application to the European Union shows agglomeration in core areas of high technology, large scale manufacturing, and producer service industries. Peripheral countries are shown to specialize in agriculture, extractives, low technology manufacturing, and standardized production. Detailed examination of two peripheral economies, Ireland and Denmark, finds that each departs from the mean of peripheral nations. A comparison of proxied trade data to actual trade data indicates that the location quotient method is a statistically viable means of proxying trade patterns

Innovation processes and industrial districts

In this survey, we examine the operations of innovation processes within industrial districts by exploring the ways in which differentiation, specialization, and integration affect the generation, diffusion, and use of new knowledge in such districts. We begin with an analysis of the importance of the division of labour and then investigate the effects of social embeddedness on innovation. We also consider the effect of forms of organization within industrial districts at various stages of product and process life, and we examine the negative aspects of embeddedness for innovation. We conclude with a discussion of the possible consequences of new information and communications technologies on innovation in industrial districts

6. The 1960s

From David Moore – “I served as dean of the ILR School during the 1960s. This was a period that started in relative tranquility and ended in tumultuous disarray with students demonstrating, administrators trying to maintain control, and faculty worrying about traditional academic freedom and values.” Includes: Remembrances of Things Past – 1963-71; Creation of the Public Employment Relations Board; and Alumni Perspectives

AN ECONOMIC EVALUATION OF LOW INVESTMENT SWINE PRODUCTION SYSTEMS

This publication summarizes an evaluation of smaller and lower investment swine production systems. The systems analyzed range from pasture operations with production during the warmer months to rather intense year-round use of remodeled buildings. In each case the system emphasizes use of facilities that can be constructed and remodeled by the farm operator. The report includes one section for each type of hog production: feeder pig production, farrow-to-finish operations and hog finishing.Livestock Production/Industries,

Assessing Laws and Legal Authorities for Obesity Prevention and Control

This is the first paper in a two part series on the laws and legal authorities for obesity prevention and control, which resulted from the National Summit on Legal Preparedness for Obesity Prevention and Control in 2008. In this paper, the authors apply the “laws and legal authorities” component of the Centers for Disease Control and Prevention (CDC) legal framework on public health legal preparedness to demonstrate the essential role that law can play in the fight against obesity. Their analysis identified numerous laws and policies in the three vital domains of healthy lifestyles, healthy places, and healthy societies. For example, in terms of healthy lifestyles, governments can impact nutrition through: food subsidies, taxation, and bans; food marketing strategies; and nutritional labeling and education. With regard to healthy places, state and local governments can apply zoning laws and policy decisions to change the environment to encourage healthy eating and physical activity. Governments can promote healthy societies through laws and legal authorities that affect the ability to address obesity from a social perspective (such as antidiscrimination law, health care insurance and benefit design, school and day care for children, and surveillance). This paper describes instances of how current laws and legal authorities affect the public health goal of preventing obesity in both positive and negative ways. It also highlights the progressive use of laws at every level of government (i.e., federal, state, and local) and the interaction of these laws as they relate to obesity prevention and control. In addition, general gaps in the use of law for obesity prevention and control are identified for attention and action. (These gaps serve as the basis for the companion paper, which delineates options for policymakers, practitioners, and other key stakeholders in the improvement of laws and legal authorities for obesity prevention and control.

Inhibition of NAADP signalling on reperfusion protects the heart by preventing lethal calcium oscillations via two-pore channel 1 and opening of the mitochondrial permeability transition pore

Aims In the heart, a period of ischaemia followed by reperfusion evokes powerful cytosolic Ca2+ oscillations that can cause lethal cell injury. These signals represent attractive cardioprotective targets, but the underlying mechanisms of genesis are ill-defined. Here, we investigated the role of the second messenger nicotinic acid adenine dinucleotide phosphate (NAADP), which is known in several cell types to induce Ca2+ oscillations that initiate from acidic stores such as lysosomes, likely via two-pore channels (TPCs, TPC1 and 2). Methods and results An NAADP antagonist called Ned-K was developed by rational design based on a previously existing scaffold. Ned-K suppressed Ca2+ oscillations and dramatically protected cardiomyocytes from cell death in vitro after ischaemia and reoxygenation, preventing opening of the mitochondrial permeability transition pore. Ned-K profoundly decreased infarct size in mice in vivo. Transgenic mice lacking the endo-lysosomal TPC1 were also protected from injury. Conclusion NAADP signalling plays a major role in reperfusion-induced cell death and represents a potent pathway for protection against reperfusion injury

PDV Detector Monitor System

Author Institution: Los Alamos National LaboratoryAuthor Institution: Lawrence Livermore National LaboratoryAuthor Institution: National Security Technologies, LLCSlides presented at the 2nd Annual Photonic Doppler Velocimetry (PDV) Workshop held at Lawrence Livermore National Laboratory, Livermore, California, August 16-17, 2007

The human urinary microbiome; bacterial DNA in voided urine of asymptomatic adults

The urinary microbiome of healthy individuals and the way it alters with ageing have not been characterised and may influence disease processes. Conventional microbiological methods have limited scope to capture the full spectrum of urinary bacterial species. We studied the urinary microbiota from a population of healthy individuals, ranging from 26 to 90 years of age, by amplification of the 16S rRNA gene, with resulting amplicons analysed by 454 pyrosequencing. Mid-stream urine was collected by the ‘clean-catch’ method. Quantitative PCR of 16S rRNA genes in urine samples, allowed relative enumeration of the bacterial loads. Analysis of the samples indicates that females had a more heterogeneous mix of bacterial genera compared to the male samples and generally had representative members of the phyla Actinobacteria and Bacteroidetes. Analysis of the data leads us to conclude that a ‘core’ urinary microbiome could potentially exist, when samples are grouped by age with fluctuation in abundance between age groups. The study also revealed age-specific genera Jonquetella, Parvimonas, Proteiniphilum and Saccharofermentans. In conclusion, conventional microbiological methods are inadequate to fully identify around two-thirds of the bacteria identified in this study. Whilst this proof-of-principle study has limitations due to the sample size, the discoveries evident in this sample data are strongly suggestive that a larger study on the urinary microbiome should be encouraged and that the identification of specific genera at particular ages may be relevant to pathogenesis of clinical conditions

Assessment of Ventilation Management Training Workshops

To achieve optimum swine performance, producer understanding of environmental control systems in mechanically or naturally ventilated facilities is extremely important. A ventilation workshop: “Managing Your Unseen Employee: The Ventilation System” was established. The primary objective of the training was to give swine producers and managers enough quality information so they could go back to their operations and properly assess their own ventilation systems and make appropriate adjustments as needed. The training workshops were established to be a multi-state and multi-disciplinary effort between South Dakota, Nebraska, Iowa and Minnesota universities. Ag engineers and animal scientists from each state participated in developing the workshop materials and delivery of the program. Four basic needs emerged that would enhance program delivery. These needs included basic environmental factors and their effects on pigs, ventilation system design principles, trouble-shooting ventilation problems, and hands-on demonstrations of instrumentation and ventilation equipment. A 1.8 m by 2.4 m by 2.4 m mobile ventilation room was used for the hands-on training. The mobile ventilation room was equipped with two variable-speed, 30-centimeter fans and one 30-cm, single-speed fan; a four-stage controller; and three types of air inlets. From 2002 to 2007, over 1000 people producing over 20 million pigs participated in more than 60 workshops. The backgrounds of participants included managers, feed consultants, extension educators, and veterinarians. Key points gained by producers included proper ventilation settings, trouble-shooting techniques, temperature control, and the effects of static pressure on airflow