Young British Women and Wine: Preloading is Safe Drinking

Purpose –This paper forms part of a larger PhD study at the University of Wales InstituteCardiff, entitled Alcohol Related Attitudes, Cultures and Behaviours in Young Adults;Challenging Perceived Wisdoms. The purpose of this work-in-progress paper is to investigatethe reasoning behind pre-loading with wine amongst young UK females between the ages of 18 and 30. Design/methodology/ approach –Two groups of young female adult alcohol consumers wereidentified. The participants in group one were aged between 18 and 30 and were either studying at degree level or had completed a degree; the participants in group two were aged between 18 and 30 and had never studied or completed at degree level. 650 questionnaireswere completed, 325 in each sample group. Follow up focus groups will be carried out withrepresentatives from each group. Findings –The results suggest that pre-loading is not always an issue related to safeconsumption habits, instead it may relate to the issue of personal safety and security. Furthermore, there are distinct differences of gender when the consumption of wine isconsidered within pre-loading and the public consumption arena. Practical Implications – More, accurate information should be available if personal safetyand security of consumers is to be increased within the public consumption arena. The perception that personal safety and security is more important than heavy wine-consumptionmay be leading to harmful behaviour on the part of young UK females.Originality value –This paper produces new insights into current wine drinking behavioursin differing groups of young UK female adults aged between 18 and 30. Specifically it compares behavioural norms between graduate and non-graduate populations

SIMULATING THE PERFORMANCE OF A MULTIPLE EXCHANGE MECHANISM MARKET

Industrial Organization,

Star Formation in the Circumnuclear Environment of NGC1068

We present near-infrared emission line images of the circumnuclear ring in NGC1068. We have measured the Br_gamma fluxes in a number of star forming complexes and derived extinctions for each of these by comparison with H_alpha. We investigate the star forming histories of these regions and find that a short burst of star formation occured co-evally throughout the ring within the last 30-40 Myr, and perhaps as recently as 4-7 Myr ago. The 1-0 S(1) flux and S(1)/Br_gamma ratios indicate that as well as fluorescence, shock excited H_2 emission contributes to the total flux. There is excess H_2 flux to the North-West where the ionisation cone crosses the ring, and we have shown it is possible that the non-stellar continuum from the Seyfert nucleus which produces the high excitation lines could also be causing fluorescence at the edges of molecular clouds in the ring. The nuclear 1-0 S(1) is more extended than previously realised but only along the bar's major axis, and we consider mechanisms for its excitation.Comment: 10 pages, 4 figures, LaTeX (mn.sty & psfig.sty). Accepted for publication in MNRA

Paramedic and student midwives' experiences of interprofessional learning

The World Health Organisation (WHO, 2010) recognises that interprofessional learning (IPL) in education institutes is an innovative strategy in mitigating the health workforce crisis and improving patient outcomes. Almost 50 years of evidence has enabled the WHO and its partners to conclude that IPL is a part of education that will shape an effective and collaborative workforce, which will ultimately support local health needs. Furthermore Barr, Helme and D'Avray (2014) highlighted that IPL should be embedded across university programmes, in order to maximise the learning experiences of healthcare students

BIMA N2H+ 1-0 mapping observations of L183 -- fragmentation and spin-up in a collapsing, magnetized, rotating, pre-stellar core

We have used the Berkeley-Illinois-Maryland Array (BIMA) to make deep N2H+ 1-0 maps of the pre-stellar core L183, in order to study the spatial and kinematic substructure within the densest part of the core. Three spatially and kinematically distinct clumps are detected, which we label L183-N1, L183-N2 and L183-N3. L183-N2 is approximately coincident with the submillimetre dust peak and lies at the systemic velocity of L183. Thus we conclude that L183-N2 is the central dense core of L183. L183-N1 and 3 are newly-discovered fragments of L183, which are marked by velocity gradients that are parallel to, but far stronger than, the velocity gradient of L183 as a whole, as detected in previous single-dish data. Furthermore, the ratio of the large-scale and small-scale velocity gradients, and the ratio of their respective size-scales, are consistent with the conservation of angular momentum for a rotating, collapsing core undergoing spin-up. The inferred axis of rotation is parallel to the magnetic field direction, which is offset from its long axis, as we have seen in other pre-stellar cores. Therefore, we propose that we have detected a fragmenting, collapsing, filamentary, pre-stellar core, rotating about its B-field, which is spinning up as it collapses. It will presumably go on to form a multiple protostellar system.Comment: 7 figures, 1 table, 21 pages, accepted for publication in Ap

Investor Sentiment and Noise Traders: Discount to Net Asset Value in Listed Property Companies in the U.K.

There are parallels between the operation of closed-end funds and in the United Kingdom property companies. In both types of corporations, the market capitalization is commonly less than the net asset value (NAV) of the assets owned by the firms. This article investigates the relationship between the NAV of U.K. property companies and their market capitalizations. We first examine the hypothesis that discounts are the result of agency costs, contingent capital gains tax liability and a number of other firm specific factors. We then examine the hypothesis that discounts result from the interaction of noise traders and rational investors. The evidence suggests that both hypotheses have utility in explaining property company discounts.

Ligand regulation of the quaternary organization of cell surface M3 muscarinic acetylcholine receptors analyzed by fluorescence resonance energy transfer (FRET) imaging and homogenous time-resolved FRET

Flp-In T-REx 293 cells expressing a wild type human M muscarinic acetylcholine receptor construct constitutively and able to express a Receptor Activated Solely by Synthetic Ligand (RASSL) form of this receptor on demand maintained response to the muscarinic agonist carbachol but developed response to clozapine-N-oxide only upon induction of the RASSL. The two constructs co-localized at the plasma membrane and generated strong ratiometric fluorescence resonance energy transfer (FRET) signals consistent with direct physical interactions. Increasing levels of induction of the FRET-donor RASSL did not alter wild type receptor FRET-acceptor levels substantially. However, ratiometric FRET was modulated in a bell-shaped fashion with maximal levels of the donor resulting in decreased FRET. Carbachol, but not the antagonist atropine, significantly reduced the FRET signal. Cell surface homogenous time-resolved FRET, based on SNAP-tag technology and employing wild type and RASSL forms of the human M receptor expressed stably in Flp-In TREx 293 cells, also identified cell surface dimeric/oligomeric complexes. Now, however, signals were enhanced by appropriate selective agonists. At the wild type receptor large increases in FRET signal to carbachol and acetylcholine were concentration-dependent with EC values consistent with the relative affinities of the two ligands. These studies confirm the capacity of the human M muscarinic acetylcholine receptor to exist as dimeric/oligomeric complexes at the surface of cells and demonstrate that the organization of such complexes can be modified by ligand binding. However, conclusions as to the effect of ligands on such complexes may depend on the approach used

Fair or Foul: When Does Media Accusation of Performance Enhancing Drug Use Become Tortious?

The Steroids Era in baseball refers to the recent period in the MLB where many players and trainers have been found guilty or been implicated in the use of performance enhancing drugs which leads to sharp increases in player talent. The stigma associated with PED use, and also any other form of cheating, has proven to be a fast track to shame in the world of Major League Baseball. This article addresses the current state of defamation law in New York and the Federal Courts by analyzing the recent statement made by Skip Bayless concerning use of Performance Enhancing Drugs by Yankees\u27 Shortstop Derek Jeter and the possibility that such statements could create tort liability. The article also considers the possible future paths of defamation law by comparing the level of protection the media enjoys today and the level of protection it may expect in the future