582 research outputs found

    Improved Linear Algebra Methods for Redshift Computation from Limited Spectrum Data - II

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    Given photometric broadband measurements of a galaxy, Gaussian processes may be used with a training set to solve the regression problem of approximating the redshift of this galaxy. However, in practice solving the traditional Gaussian processes equation is too slow and requires too much memory. We employed several methods to avoid this difficulty using algebraic manipulation and low-rank approximation, and were able to quickly approximate the redshifts in our testing data within 17 percent of the known true values using limited computational resources. The accuracy of one method, the V Formulation, is comparable to the accuracy of the best methods currently used for this problem

    Hepatitis and Strict Liability

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    Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis

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    Background A substantial number of epidemiologic studies have provided estimates of the relation between exposure to benzene at work and the risk of leukemia, but the results have been heterogeneous. To bridge this gap in knowledge, we synthesized the existing epidemiologic evidence on the relation between occupational exposure to benzene and the risk of leukemia, including all types combined and the four main subgroups acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), chronic lymphocytic leukemia (CLL), and chronic myeloid leukemia (CML). Methods A systematic literature review was carried out using two databases 'Medline' and 'Embase' from 1950 through to July 2009. We selected articles which provided information that can be used to estimate the relation between benzene exposure and cancer risk (effect size). Results In total 15 studies were identified in the search, providing 16 effect estimates for the main analysis. The summary effect size for any leukemia from the fixed-effects model was 1.40 (95% CI, 1.23-1.57), but the study-specific estimates were strongly heterogeneous (I2 = 56.5%, Q stat = 34.47, p = 0.003). The random-effects model yielded a summary- effect size estimate of 1.72 (95% CI, 1.37-2.17). Effect estimates from 9 studies were based on cumulative exposures. In these studies the risk of leukemia increased with a dose-response pattern with a summary-effect estimate of 1.64 (95% CI, 1.13-2.39) for low (< 40 ppm-years), 1.90 (95% CI, 1.26-2.89) for medium (40-99.9 ppm-years), and 2.62 (95% CI, 1.57-4.39) for high exposure category (> 100 ppm-years). In a meta-regression, the trend was statistically significant (P = 0.015). Use of cumulative exposure eliminated heterogeneity. The risk of AML also increased from low (1.94, 95% CI, 0.95-3.95), medium (2.32, 95% CI, 0.91-5.94) to high exposure category (3.20, 95% CI, 1.09-9.45), but the trend was not statistically significant. Conclusions Our study provides consistent evidence that exposure to benzene at work increases the risk of leukemia with a dose-response pattern. There was some evidence of an increased risk of AML and CLL. The meta-analysis indicated a lack of association between benzene exposure and the risk of CML

    Adoptions for the Hard-to-Place: The Role of the Court and the Trend Against Matching

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    Hepatitis and Strict Liability

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    Adoptions for the Hard-to-Place: The Role of the Court and the Trend Against Matching

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    Evidence Based Criteria Diagnosis and Management of Decompensating Heterophoria

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    Introduction: Decompensating exophoria at near is a common condition in optometry practice. The main treatment options for the disorder are relieving prism and Vision Therapy. The prism prescribing techniques are usually derived from two methods: the FD method or the FR method. Neither of these methods is entirely successful. A more recently acknowledged clinical observation in decompensating heterophoria is a reduction in stereopsis. This project aims to investigate the incorporation of global stereopsis testing in prism prescribing for heterophoria. Materials and Methods: A total of 185 participants were recruited. A Stereo Prism Criterion (SPC) was developed: the minimum prism to achieve maximum global stereoacuity on TNO. A relieving prism was prescribed according to Sheard’s Criterion, SPC and FD methods in double-blind crossover studies. 35 participants subsequently underwent VT. The participant’s satisfaction was evaluated using a symptom-based questionnaire. Results: The SPC contributed to a higher prism than Sheard’s and FD (p<0.01) and to greater symptom relief (p<0.01). The TNO is more affected by heterophoria decompensation than local stereo tests. Unlike the other two methods, the SPC prism resulted in a normal level of symptoms (p<0.01). VT using this prism helped reduce signs of decompensation, including symptoms (p<0.01), and improve stereoacuity (p<0.01). Conclusion: The TNO test, known for its sensitivity to decompensating exophoria, has provided a better relieving prism than the commonly used Sheard’s criterion and the FD method. Importantly, the level of symptoms approached that of normal patients without any statistical difference. This suggests that SPC for prescribing prism can be recommended to be used in optometry practice

    Livestock-associated MRSA colonization of occupational exposed workers and households in Europe: a review

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    The worldwide escalation in antibiotic resistant microorganisms has sustained the increasing concerns regarding antibiotics extensive use in animal food industry, which can result in a selection pressure that is driving the emergence of strains such as methicillin-resistant staphylococcus aureus (MRSA). Human MRSA infections are a well-known cause of numerous hospitalizations and deaths associated with extremely high mortality rates for invasive infections. Both animals and humans can become bacterial reservoirs of Livestock Associated MRSA (LA-MRSA) in which colonization predisposes to staphylococcal acquisition in clinical settings and to transfer the infection to others including household members. Biomonitoring of occupational exposed individuals which spend several hours per day in direct contact with MRSA-positive animals and thus are irrefutably exposed to a high risk of nasal colonization is imperative in order to develop effective preventive strategies. Here we performed an extensive review regarding the prevalence of LA- MRSA colonization in both occupational exposed individuals and their house-holds in a European context.info:eu-repo/semantics/publishedVersio
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