Luminous and Dark Matter in the Milky Way

(Abridged) Axisymmetric models of the Milky Way exhibit strong interrelations between the Galactic constants (R_0 and T_0), the stellar columndensity (S_*) and the shape of the dark matter (DM) halo. Here we present analytical relations that can be used to investigate the effects of the uncertain gaseous velocity dispersion on the HI flaring constraints. The contribution of cosmic rays and magnetic fields to the pressure gradients is small. A significantly flattened dark matter halo is only possible if R_0 <~ 6.8 kpc. If R_0 is larger than ~7 kpc, or T_0 >~ 170 km/s, we can rule out two DM candidates that require a highly flattened DM halo: 1) decaying massive neutrinos; and 2) a disk of cold molecular hydrogen. It is only possible to construct self-consistent models of the Galaxy based on the IAU-recommended values for the Galactic constants in the unlikely case that the the stellar columndensity is smaller than ~18 M_sun/pc^2. If we assume that the halo is oblate and S_* = 35 +/- 5 M_sun/pc^2, R_0 <~ 8 kpc and T_0 <~ 200 km/s. Combining the best kinematical and star-count estimates of S_*, we conclude that: 25 <~ S_* <~ 45 M_sun/pc^2. Kuijken & Gilmore's (1991) determination of the columndensity of matter with |z|<=1.1 kpc is robust and valid over a wide range of Galactic constants. Our mass models show that the DM density in the Galactic centre is uncertain by a factor 1000. In the Solar neighbourhood we find: rho_DM ~0.42 GeV/c^2/cm^3 or (11 +/- 5) mM_sun/pc^3 -- roughly 15% of rho_tot.Comment: Accepted for publication in MNRA

The DiskMass Survey. I. Overview

We present a survey of the mass surface-density of spiral disks, motivated by outstanding uncertainties in rotation-curve decompositions. Our method exploits integral-field spectroscopy to measure stellar and gas kinematics in nearly face-on galaxies sampled at 515, 660, and 860 nm, using the custom-built SparsePak and PPak instruments. A two-tiered sample, selected from the UGC, includes 146 nearly face-on galaxies, with B<14.7 and disk scale-lengths between 10 and 20 arcsec, for which we have obtained H-alpha velocity-fields; and a representative 46-galaxy subset for which we have obtained stellar velocities and velocity dispersions. Based on re-calibration of extant photometric and spectroscopic data, we show these galaxies span factors of 100 in L(K) (0.03 < L/L(K)* < 3), 8 in L(B)/L(K), 10 in R-band disk central surface-brightness, with distances between 15 and 200 Mpc. The survey is augmented by 4-70 micron Spitzer IRAC and MIPS photometry, ground-based UBVRIJHK photometry, and HI aperture-synthesis imaging. We outline the spectroscopic analysis protocol for deriving precise and accurate line-of-sight stellar velocity dispersions. Our key measurement is the dynamical disk-mass surface-density. Star-formation rates and kinematic and photometric regularity of galaxy disks are also central products of the study. The survey is designed to yield random and systematic errors small enough (i) to confirm or disprove the maximum-disk hypothesis for intermediate-type disk galaxies, (ii) to provide an absolute calibration of the stellar mass-to-light ratio well below uncertainties in present-day stellar-population synthesis models, and (iii) to make significant progress in defining the shape of dark halos in the inner regions of disk galaxies.Comment: To appear in ApJ; 72 pages, 3 tables, 18 figures. High-resolution version available at http://www.astro.wisc.edu/~mab/publications/DMS_I_preprint.pd

Multiscale scenarios for nature futures

Targets for human development are increasingly connected with targets for nature, however, existing scenarios do not explicitly address this relationship. Here, we outline a strategy to generate scenarios centred on our relationship with nature to inform decision-making at multiple scales

The spatio-temporal dynamics of conditioned behavior: First-order and higher-order conditioning

Pavlovian conditioning procedures generate spatially and temporally distinct behaviors. For example, after rats have received pairings of a lever with food, they approach the food well during the lever (called goal-tracking) and interact with it (called sign-tracking); with these two spatially distinct behaviors being distributed differently across the temporal duration of the lever. Experiment 1 assessed the development of these spatio-temporally defined behaviors during first-order conditioning, as a function of the sequence in which the lever and food occurred (lever→food or food→lever) and the interval between them (1s or 11s). In Experiment 2, the same rats received higher-order conditioning trials in which an auditory stimulus was paired with the lever and the emergence of goal-tracking to the auditory stimulus was assessed. The results of Experiments 1 and 2 revealed dissociations between where and when learning was evident during first- and higher-order conditioning, underscoring the need for models of Pavlovian conditioning to explain both the nature and timing of different conditioned responses

Severe early onset preeclampsia: short and long term clinical, psychosocial and biochemical aspects

Preeclampsia is a pregnancy specific disorder commonly defined as de novo hypertension and proteinuria after 20 weeks gestational age. It occurs in approximately 3-5% of pregnancies and it is still a major cause of both foetal and maternal morbidity and mortality worldwide1. As extensive research has not yet elucidated the aetiology of preeclampsia, there are no rational preventive or therapeutic interventions available. The only rational treatment is delivery, which benefits the mother but is not in the interest of the foetus, if remote from term. Early onset preeclampsia (<32 weeks’ gestational age) occurs in less than 1% of pregnancies. It is, however often associated with maternal morbidity as the risk of progression to severe maternal disease is inversely related with gestational age at onset2. Resulting prematurity is therefore the main cause of neonatal mortality and morbidity in patients with severe preeclampsia3. Although the discussion is ongoing, perinatal survival is suggested to be increased in patients with preterm preeclampsia by expectant, non-interventional management. This temporising treatment option to lengthen pregnancy includes the use of antihypertensive medication to control hypertension, magnesium sulphate to prevent eclampsia and corticosteroids to enhance foetal lung maturity4. With optimal maternal haemodynamic status and reassuring foetal condition this results on average in an extension of 2 weeks. Prolongation of these pregnancies is a great challenge for clinicians to balance between potential maternal risks on one the eve hand and possible foetal benefits on the other. Clinical controversies regarding prolongation of preterm preeclamptic pregnancies still exist – also taking into account that preeclampsia is the leading cause of maternal mortality in the Netherlands5 - a debate which is even more pronounced in very preterm pregnancies with questionable foetal viability6-9. Do maternal risks of prolongation of these very early pregnancies outweigh the chances of neonatal survival? Counselling of women with very early onset preeclampsia not only comprises of knowledge of the outcome of those particular pregnancies, but also knowledge of outcomes of future pregnancies of these women is of major clinical importance. This thesis opens with a review of the literature on identifiable risk factors of preeclampsia

Reconstruction of primary vertices at the ATLAS experiment in Run 1 proton–proton collisions at the LHC

This paper presents the method and performance of primary vertex reconstruction in proton–proton collision data recorded by the ATLAS experiment during Run 1 of the LHC. The studies presented focus on data taken during 2012 at a centre-of-mass energy of √s=8 TeV. The performance has been measured as a function of the number of interactions per bunch crossing over a wide range, from one to seventy. The measurement of the position and size of the luminous region and its use as a constraint to improve the primary vertex resolution are discussed. A longitudinal vertex position resolution of about 30μm is achieved for events with high multiplicity of reconstructed tracks. The transverse position resolution is better than 20μm and is dominated by the precision on the size of the luminous region. An analytical model is proposed to describe the primary vertex reconstruction efficiency as a function of the number of interactions per bunch crossing and of the longitudinal size of the luminous region. Agreement between the data and the predictions of this model is better than 3% up to seventy interactions per bunch crossing

Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan

This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements