Epilepsy Therapy Goes Viral.

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Underlying Inflation in Australia: Are the Existing Measures Satisfactory?

Along with a number of other central banks around the world the Reserve Bank of Australia has quite explicitly adopted an inflation target. Both the Bank and the Australian Government’s statistical agency (the Australian Bureau of Statistics) report various measures of the underlying rate of inflation. The aim of this paper is to formulate criteria which an acceptable underlying rate must satisfy and then test to see whether either individually or in combination any of the current (CPI Excluding volatile items; CPI Market prices excluding volatile items; Weighted median and; Trimmed mean) or recently discarded (the Treasury underlying rate) measures of underlying inflation satisfy these criteria. We find that for the period since inflation targeting began (in 1993) none of these underlying series satisfy all of the criteria we propose but that one series (the RBA’s Trimmed mean series) does satisfy the sub-set which we refer to as our ‘necessary criteria’. We then examine the results of an ‘Unobserved Components’ decomposition and argue that it provides useful information on underlying inflation in Australia. JEL Codes E31, C4 Keywords:Inflation Monetary Policy Time Series Econometrics

Tandem ring-closing metathesis reaction with a ruthenium catalyst containing a N-heterocyclic ligand

The highly active catalyst 2 was used in tandem RCM to make molecules with various ring systems containing α,β-unsaturated carbonyl compounds

Sudden Decoherence Transitions for Quantum Discord

We investigate the disappearance of discord in 2- and multi-qubit systems subject to decohering influences. We formulate the computation of quantum discord in terms of the generalized Bloch vector, which gives useful insights on the time evolution of quantum coherence for the open system, particularly the comparison of entanglement and discord. And we show that the analytical calculation of the global geometric discord is NP-hard in the number of qubits. We present an efficient numerical method to calculating the quantum discord for a certain important class of multipartite states. In agreement with previous work for 2-qubit cases, (Mazzola et al., Phys. Rev. Lett. 104, 200401 (2010)), we find situations in which there is a sudden transition from classical to quantum decoherence characterized by the discord remaining relatively robust (classical decoherence) until a certain point from where it begins to decay quickly whereas the classical correlation decays more slowly (quantum decoherence). However, we find that as the number of qubits increases, the chance of this kind of transition occurring becomes small.Comment: 15 pages, 2 figure

Larger mammalian body size leads to lower retroviral activity

Retroviruses have been infecting mammals for at least 100 million years, leaving descendants in host genomes known as endogenous retroviruses (ERVs). The abundance of ERVs is partly determined by their mode of replication, but it has also been suggested that host life history traits could enhance or suppress their activity. We show that larger bodied species have lower levels of ERV activity by reconstructing the rate of ERV integration across 38 mammalian species. Body size explains 37% of the variance in ERV integration rate over the last 10 million years, controlling for the effect of confounding due to other life history traits. Furthermore, 68% of the variance in the mean age of ERVs per genome can also be explained by body size. These results indicate that body size limits the number of recently replicating ERVs due to their detrimental effects on their host. To comprehend the possible mechanistic links between body size and ERV integration we built a mathematical model, which shows that ERV abundance is favored by lower body size and higher horizontal transmission rates. We argue that because retroviral integration is tumorigenic, the negative correlation between body size and ERV numbers results from the necessity to reduce the risk of cancer, under the assumption that this risk scales positively with body size. Our model also fits the empirical observation that the lifetime risk of cancer is relatively invariant among mammals regardless of their body size, known as Peto's paradox, and indicates that larger bodied mammals may have evolved mechanisms to limit ERV activity

Decent Work in America: The 2005 Work Environment Index

What are the factors that make for a decent work environment and how do the conditions of work vary in different parts of the United States? To address these and similarly important questions in a clear and accessible way, we have developed a new approach for measuring the work environment on a state-bystate basis throughout the United States (including the District of Columbia) – the Work Environment Index (WEI). This is the first installment of the WEI, and we intend to update it every year. The WEI is a unique social indicator that brings together in one measure a range of factors that, in combination, define the quality of our working lives in the U.S. today. The WEI examines three basic dimensions of the U.S. work environment: job opportunities, job quality and workplace fairness. We rank the 50 states and the District of Columbia according to these three categories. Based on our measures of job opportunities, job quality, and workplace fairness, we find that, overall, Delaware offers the best relative work environment in the United States. Other states with high WEI rankings include New Hampshire, Minnesota, Vermont and Iowa. The states with the lowest WEI rankings are Louisiana, Texas, Arkansas, Utah, South Carolina and Mississippi. Our state-by-state WEI ranking enables us to consider a crucial and widely-discussed issue: Do the states that provide a relatively decent work environment end up paying a penalty in terms of their overall economic climate? For example, do states that rank high according to the WEI score poorly in terms of their overall growth rate, the pace at which new businesses are being formed in the state, or their rate of new job creation? In fact, we find that overall economic conditions in states with a high WEI rank are at least as favorable, if not somewhat more favorable, than those with low WEI rankings. Along with this, we also find that poverty rates in states with high WEI rankings are consistently lower than states with low WEI rankings.labor, work environment, business climate, decent work, poverty, job growth, economic growth, business start-up

Force and Mass Dynamics in Non-Newtonian Suspensions

Above a certain solid fraction, dense granular suspensions in water exhibit non-Newtonian behavior, including impact-activated solidification. Although it has been suggested that solidification depends on boundary interactions, quantitative experiments on the boundary forces have not been reported. Using high-speed video, tracer particles, and photoelastic boundaries, we determine the impactor kinematics and the magnitude and timings of impactor-driven events in the body and at the boundaries of cornstarch suspensions. We observe mass shocks in the suspension during impact. The shockfront dynamics are strongly correlated to those of the intruder. However, the total momentum associated with this shock never approaches the initial impactor momentum. We also observe a faster second front, associated with the propagation of pressure to the boundaries of the suspension. The two fronts depend differently on the initial impactor speed, $v_0$, and the suspension packing fraction. The speed of the pressure wave is at least an order of magnitude smaller than (linear) ultrasound speeds obtained for much higher frequencies, pointing to complex amplitude and frequency response of cornstarch suspensions to compressive strains

AN EMPLOYMENT EQUATION FOR AUSTRALIA: 1966-2001

We model the relationship between hours of work and employment and argue that unless actual hours are varying with a change in ‘standard hours’, actual hours should not appear in the long-run component of an equation for employment. If however standard hours are changing then it is desirable that this variable be incorporated into the employment equation. Our theoretical model yields an expression for the elasticity of employment with respect to standard hours which shows that the elasticity is related to the size of the premium for overtime. Using quarterly data for the period 1966:3 – 2001:3 we estimate a new employment equation for Australia incorporating standard hours of work. We find empirical support for our approach and we provide new estimates of the elasticity of employment with respect to the real wage and GDP. We also find a marked asymmetry in the response of employment to variations in real GDP and real wages in recession periods as against non-recession periods.Employment Determination, Demand for Labor, Australia

The Work Environment Index: Technical Background Paper

The vast majority of Americans work for a living. The track record of different states varies widely when it comes to providing decent opportunities for working people. The Work Environment Index (WEI) captures these differences and provides a basis for evaluating how well each state does in creating an economy that supports its working population. The purpose of this article is to detail the construction of the WEI and to explain the design of the Index. This paper serves as a technical companion to the report Decent Work In America: The 2005 Work Environment Index. Many factors contribute to a good environment for working people: quality jobs, adequate opportunities for employment, basic social protections, and being treated fairly. The WEI is a composite measure of these different dimensions and provides a basis for comparing the quality of the work environment in all 50 states and the District of Columbia. The WEI has multiple objectives: 1) to capture and quantify the various dimensions of the work environment on a state-by-state basis. 2) to provide a direct, relatively transparent, and easy-to-understand measurement that is firmly rooted in publicly available data sources. 3) to provide a basis for making comparisons between the states that are fair and objective. 4) to create a tool for analyzing other socio-economic issues at the state level: e.g. poverty rate differentials, job quality and quantity trade-offs, and patterns of economic growth.labor, work environment, business climate, decent work, poverty, job growth, economic growth, business start-ups