How do cardiologists select patients for dual antiplatelet therapy continuation beyond 1 year after a myocardial infarction? Insights from the EYESHOT Post-MI Study

Background: Current guidelines suggest to consider dual antiplatelet therapy (DAPT) continuation for longer than 12 months in selected patients with myocardial infarction (MI). Hypothesis: We sought to assess the criteria used by cardiologists in daily practice to select patients with a history of MI eligible for DAPT continuation beyond 1 year. Methods: We analyzed data from the EYESHOT Post-MI, a prospective, observational, nationwide study aimed to evaluate the management of patients presenting to cardiologists 1 to 3 years from the last MI event. Results: Out of the 1633 post-MI patients enrolled in the study between March and December 2017, 557 (34.1%) were on DAPT at the time of enrolment, and 450 (27.6%) were prescribed DAPT after cardiologist assessment. At multivariate analyses, a percutaneous coronary intervention (PCI) with multiple stents and the presence of peripheral artery disease (PAD) resulted as independent predictors of DAPT continuation, while atrial fibrillation was the only independent predictor of DAPT interruption for patients both at the second and the third year from MI at enrolment and the time of discharge/end of the visit. Conclusions: Risk scores recommended by current guidelines for guiding decisions on DAPT duration are underused and misused in clinical practice. A PCI with multiple stents and a history of PAD resulted as the clinical variables more frequently associated with DAPT continuation beyond 1 year from the index MI

Aspectos procesales de la imputación penal a la persona jurídica

Es una publicación realizada en colaboración con el Departamento de Derecho Penal y Procesal Penal de la Universidad Austral

Beni culturali e soggetti coinvolti in percorsi turistici: anelli di un itinerario adriatico di lunga percorrenza

Il contributo parte da una ricerca internazionale cui l'a. ha partecipato "Routes for tourism and culture" in cui erano coinvolte sette universit\ue0 (Italia, Germania, Gracia e Portogallo). Il lavoro ha avuto seguito con il rilevamento e lo studio paesaggistico, agrario e di beni culturali e con l'elaborazione un itinerario di lunga percorrenza adriatico (del vino e dell'olio), dal quale si staccano anelli di dettaglio anche con l'uso di tecniche e strumentazioni ICT. Questa ricerca ne fa la sintesi e tratta del coinvogimento di ulteriori stakeholders. Qui ci si sofferma su un anello tematico (Castelli scaligeri veronesi) e su uno integrale (la SP Cingolana delle Marche)

Conductas neutrales

Es una publicación realizada en colaboración con el Departamento de Derecho Penal y Procesal Penal de la Universidad Austral

La autoría en los delitos tributarios

Fil: Robiglio, Carolina L. I.. Universidad de Buenos Aires. Facultad de Ciencias Económicas. Buenos Aires, Argentina

Maintaining the conservation value of shifting cultivation landscapes requires spatially Explicit Interventions

Fallow vegetation within landscapes dominated by shifting cultivation represents a woody species pool of critical importance with considerable potential for biodiversity conservation. Here, through the analysis of factors that influence the early stages of fallow vegetation regrowth in two contrasting forest margin landscapes in Southern Cameroon, we assessed the impact of current trends of land use intensification and expansion of the cultivated areas, upon the conservation potential of shifting cultivation landscapes. We combined the analysis of plot and landscape scale factors and identified a complex set of variables that influence fallow regrowth processes in particular the characteristics of the agricultural matrix and the distance from forest. Overall we observed a decline in the fallow species pool, with composition becoming increasingly dominated by species adapted to recurrent disturbance. It is clear that without intervention and if present intensification trends continue, the potential of fallow vegetation to contribute to biodiversity conservation declines because of a reduced capacity, (1) to recover forest vegetation with anything like its original species composition, (2) to connect less disturbed forest patches for forest dependent organisms. Strategies to combat biodiversity loss, including promotion of agroforestry practices and the increase of old secondary forest cover, will need not only to operate at a landscape scale but also to be spatially explicit, reflecting the spatial pattern of species reservoirs and dispersal strategies and human usage across landscapes