1,107 research outputs found
The use of coconut oil/diesel blends as a fuel for compression ignition engines (ODNRI Bulletin No. 31)
This bulletin describes experimental and evaluative work carried out by the Overseas Development Natural Resources Institute (ODNRI) to investigate fuelling of a standard compression ignition engine with blends of coconut oil and diesel. Initial studies were made of fuel-related properties for pure coconut oil and for a full range of blends with diesel. A major upgrading of the standard engine's fuel filtration system was necessary but thereafter it was found that a blend of 80% coconut oil in diesel, when heated to 45°C, provided a technically feasible substitute fuel. A limited duration engine trial was completed with this alternative arrangement to assess maintenance and operational requirements. On the basis of these results a preliminary economic evaluation was made of the potential for wider adoption of this type of substitute fuelling. Whilst this indicated that at prevailing prices of coconut oil relative to diesel this was unattractive, circumstances were identified in which this technology could have potential application
Antiviral screening identifies adenosine analogs targeting the endogenous dsRNA Leishmania RNA virus 1 (LRV1) pathogenicity factor.
The endogenous double-stranded RNA (dsRNA) virus Leishmaniavirus (LRV1) has been implicated as a pathogenicity factor for leishmaniasis in rodent models and human disease, and associated with drug-treatment failures in Leishmania braziliensis and Leishmania guyanensis infections. Thus, methods targeting LRV1 could have therapeutic benefit. Here we screened a panel of antivirals for parasite and LRV1 inhibition, focusing on nucleoside analogs to capitalize on the highly active salvage pathways of Leishmania, which are purine auxotrophs. Applying a capsid flow cytometry assay, we identified two 2'-C-methyladenosine analogs showing selective inhibition of LRV1. Treatment resulted in loss of LRV1 with first-order kinetics, as expected for random virus segregation, and elimination within six cell doublings, consistent with a measured LRV1 copy number of about 15. Viral loss was specific to antiviral nucleoside treatment and not induced by growth inhibitors, in contrast to fungal dsRNA viruses. Comparisons of drug-treated LRV1 <sup>+</sup> and LRV1 <sup>-</sup> lines recapitulated LRV1-dependent pathology and parasite replication in mouse infections, and cytokine secretion in macrophage infections. Agents targeting Totiviridae have not been described previously, nor are there many examples of inhibitors acting against dsRNA viruses more generally. The compounds identified here provide a key proof-of-principle in support of further studies identifying efficacious antivirals for use in in vivo studies of LRV1-mediated virulence
Improved Bounds on the Phase Transition for the Hard-Core Model in 2-Dimensions
For the hard-core lattice gas model defined on independent sets weighted by
an activity , we study the critical activity
for the uniqueness/non-uniqueness threshold on the 2-dimensional integer
lattice . The conjectured value of the critical activity is
approximately . Until recently, the best lower bound followed from
algorithmic results of Weitz (2006). Weitz presented an FPTAS for approximating
the partition function for graphs of constant maximum degree when
where is the
infinite, regular tree of degree . His result established a certain
decay of correlations property called strong spatial mixing (SSM) on
by proving that SSM holds on its self-avoiding walk tree
where and is an ordering on the neighbors of vertex . As
a consequence he obtained that . Restrepo et al. (2011) improved Weitz's approach for
the particular case of and obtained that
. In this paper, we establish an upper bound for
this approach, by showing that, for all , SSM does not hold on
when . We also present a
refinement of the approach of Restrepo et al. which improves the lower bound to
.Comment: 19 pages, 1 figure. Polished proofs and examples compared to earlier
versio
The electrical properties of gold and tantalum thin films after argon ion implantation.
Evaporated gold and tantalum films have been bombarded with argon ions. In the case of gold films this resulted in an increase of the sheet-resistance by sputter etching to a maximum of 40 kO/[square] . The strain-gauge coefficient of resistance (gamma) (i.e. the fractional change in resistance per unit strain) was measured for films with a wide range of sheet-resistance, and was found to be almost invariant with an average of 2.6. This contrasts. greatly with the published values of gamma of up to 100 for thin island-structure evaporated films of similar sheet-resistance. The temperature coefficient of strain-gauge factor (beta) was found to be similar in magnitude but opposite in sign to the temperature coefficient of resistivity (alpha), which was measured as +12 x 104/°C. The measured values of gamma, beta and alpha agree well with values calculated assuming metallic conduction modified by reduction of the electron mean- free-path. We, therefore, conclude that a connected metallic layer still exists at very high values of sheet-resistance. In the case of tantalum films (that contain 30 atomic per cent oxygen) conduction was found to be by a combination of metallic and activated tunnelling. In the latter case there is some evidence for an increase in importance of this mechanism with oxygen concentration and for the existence of at least two activation energies. After bombardment with low doses of argon the resistivity (p) and also alpha shifted markedly towards values expected of very pure tantalum films, probably as a result of radiation enhanced diffusion and preferential sputtering of oxygen combined with re-arrangement of the film to form large precipitates of b.c.c. tantalum. There was also a significant increase in gamma (from an average of 3 up to 5.2) at similar doses, possibly as a result of changes in the microstructure increasing the importance of strain induced changes in the metallic conduction paths in the film. The metallic phase appears to be metastable as p increases with time (up to two years) at room temperature, probably due to reaction with oxygen near the film/substrate interface. For higher doses p drops (but not in a way explainable by sputter etching) alpha changes from a large positive value to a small negative one, and gamma drops towards a value of 2 which is the predicted value for Ta. on glass. These results 'indicate that a single phase, stable, low sputtering rate compound is formed, probably by reaction with the glass substrate. This compound has a mixture of activated tunnelling and metallic conduction with the strain gauge factor apparently determined by the metallic component of conduction. Some preliminary attempts at electrical depth profiling of the bombarded tantalum films by anodization are reported and the results support the models proposed above
Single-electron transport driven by surface acoustic waves: moving quantum dots versus short barriers
We have investigated the response of the acoustoelectric current driven by a
surface-acoustic wave through a quantum point contact in the closed-channel
regime. Under proper conditions, the current develops plateaus at integer
multiples of ef when the frequency f of the surface-acoustic wave or the gate
voltage Vg of the point contact is varied. A pronounced 1.1 MHz beat period of
the current indicates that the interference of the surface-acoustic wave with
reflected waves matters. This is supported by the results obtained after a
second independent beam of surface-acoustic wave was added, traveling in
opposite direction. We have found that two sub-intervals can be distinguished
within the 1.1 MHz modulation period, where two different sets of plateaus
dominate the acoustoelectric-current versus gate-voltage characteristics. In
some cases, both types of quantized steps appeared simultaneously, though at
different current values, as if they were superposed on each other. Their
presence could result from two independent quantization mechanisms for the
acoustoelectric current. We point out that short potential barriers determining
the properties of our nominally long constrictions could lead to an additional
quantization mechanism, independent from those described in the standard model
of 'moving quantum dots'.Comment: 25 pages, 12 figures, to be published in a special issue of J. Low
Temp. Phys. in honour of Prof. F. Pobel
Statistical Survey of Type III Radio Bursts at Long Wavelengths Observed by the Solar TErrestrial RElations Observatory (STEREO)/Waves Instruments: Radio Flux Density Variations with Frequency
We have performed a statistical study of Type III radio bursts observed
by Solar TErrestrial RElations Observatory (STEREO)/Waves between May 2007 and
February 2013. We have investigated the flux density between kHz and
MHz. Both high- and low-frequency cutoffs have been observed in of
events suggesting an important role of propagation. As already reported by
previous authors, we observed that the maximum flux density occurs at MHz on
both spacecraft. We have developed a simplified analytical model of the flux
density as a function of radial distance and compared it to the STEREO/Waves
data.Comment: published in Solar Physic
Management of Avena ludoviciana and Phalaris paradoxa with barley and less herbicide in subtropical Australia
The competitive advantage of barley compared with wheat was quantified for suppressing seed production of Avena ludoviciana Durieu. (wild oats) andPhalaris paradoxa L. (paradoxa grass), and for improving herbicide effectiveness on these major winter grass weeds of the subtropical grain region of Australia. Eight field experiments were broadcast with weed seed before sowing wheat or barley, in which the emerged weeds were then treated with 4 herbicide doses (0, 25, 50, 100% of recommended rates). Yield reduction from untreated weeds was on average 4 times greater in wheat than in barley, with greater losses from A. ludoviciana than P. paradoxa. Barley did not affect weed emergence, but suppressed weed tiller density and, to a lesser extent, the number of weed seeds per tiller. Seed production was, on average, 4340 and 5105 seeds/m2 for A. ludoviciana and P. paradoxa, respectively, in untreated wheat compared with 555 and 50 seeds/m2 in untreated barley. Weed seed production following treatment with 25% herbicide rate in barley was similar or less than that after treatment with 100% herbicide rate in wheat. Overall, 25% herbicide rate was optimal for both conserving yield and minimising weed seed production in barley. For wheat, maximum yield was achieved with 50% herbicide but weed seed production was lowest with 100% herbicide rate. This indicates that weeds can be effectively controlled in barley with considerably less herbicide than required in wheat, highlighting the importance of including barley as a part of weed management strategies that aim to reduce herbicide inputs
Fitting the integrated Spectral Energy Distributions of Galaxies
Fitting the spectral energy distributions (SEDs) of galaxies is an almost
universally used technique that has matured significantly in the last decade.
Model predictions and fitting procedures have improved significantly over this
time, attempting to keep up with the vastly increased volume and quality of
available data. We review here the field of SED fitting, describing the
modelling of ultraviolet to infrared galaxy SEDs, the creation of
multiwavelength data sets, and the methods used to fit model SEDs to observed
galaxy data sets. We touch upon the achievements and challenges in the major
ingredients of SED fitting, with a special emphasis on describing the interplay
between the quality of the available data, the quality of the available models,
and the best fitting technique to use in order to obtain a realistic
measurement as well as realistic uncertainties. We conclude that SED fitting
can be used effectively to derive a range of physical properties of galaxies,
such as redshift, stellar masses, star formation rates, dust masses, and
metallicities, with care taken not to over-interpret the available data. Yet
there still exist many issues such as estimating the age of the oldest stars in
a galaxy, finer details ofdust properties and dust-star geometry, and the
influences of poorly understood, luminous stellar types and phases. The
challenge for the coming years will be to improve both the models and the
observational data sets to resolve these uncertainties. The present review will
be made available on an interactive, moderated web page (sedfitting.org), where
the community can access and change the text. The intention is to expand the
text and keep it up to date over the coming years.Comment: 54 pages, 26 figures, Accepted for publication in Astrophysics &
Space Scienc
Double-Spin Asymmetry in the Cross Section for Exclusive rho^0 Production in Lepton-Proton Scattering
Evidence for a positive longitudinal double-spin asymmetry = 0.24
+-0.11 (stat) +-0.02 (syst) in the cross section for exclusive diffractive
rho^0(770) vector meson production in polarised lepton-proton scattering was
observed by the HERMES experiment. The longitudinally polarised 27.56 GeV HERA
positron beam was scattered off a longitudinally polarised pure hydrogen gas
target. The average invariant mass of the photon-proton system has a value of
= 4.9 GeV, while the average negative squared four-momentum of the virtual
photon is = 1.7 GeV^2. The ratio of the present result to the
corresponding spin asymmetry in inclusive deep-inelastic scattering is in
agreement with an early theoretical prediction based on the generalised vector
meson dominance model.Comment: 10 pages, 4 embedded figures, LaTe
b-Jet Identification in the D0 Experiment
Algorithms distinguishing jets originating from b quarks from other jet
flavors are important tools in the physics program of the D0 experiment at the
Fermilab Tevatron p-pbar collider. This article describes the methods that have
been used to identify b-quark jets, exploiting in particular the long lifetimes
of b-flavored hadrons, and the calibration of the performance of these
algorithms based on collider data.Comment: submitted to Nuclear Instruments and Methods in Physics Research
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