1,547 research outputs found
Alaska Coastal Community Youth and the Future
The Alaska Sea Grant College Program.
Project No. R/72-02.Executive Summary / Introduction / Background to the Research / Methods / Findings / Discussion and Policy Recommendations / Products from the Research / References Cited / Appendix A. Focus Group Protocol (High School) / Appendix B. Focus Group Protocol (12-20 year olds) / Appendix C. Focus Group Questionnaire / Appendix D. Occupational Rating Worksheet / Appendix E. Consent/Assent For
Middle Columbia River Aquatic Nuisance Species Survey
Aquatic nonindigenous species (ANS) in the middle Columbia and lower Snake rivers were surveyed during the summer of 2006. The project area included eight reservoirs and the free-flowing, Hanford Reach on the Columbia River. We also conducted a literature review to create a complete list of ANS for the study area
Teaching writing to students with learning difficulties in inclusive English classrooms: Lessons from an exemplary teacher
This article reports on a case study of an exemplary teacher who was a participant in a professional learning project, WriteIdeas. The teacher provided instructional support in writing to a targeted student with learning difficulties in an inclusive Year 8 English classroom. Analytical frameworks were developed and applied to the data that had been collected from various sources. The case study sheds light on the multi-faceted nature and complexity of providing responsive and tailored instruction in writing to students in an inclusive setting. Copyright © 200
Development of Carbon Dioxide Removal Systems for Advanced Exploration Systems 2014-2015
A long-term goal for NASA is to enable crewed missions to Mars: first to the vicinity of Mars, and then to the Mars surface. These missions present new challenges for all aspects of spacecraft design in comparison with the International Space Station, as resupply is unavailable in the transit phase, and early return is not possible. Additionally, mass, power, and volume must be minimized for all phases to reduce propulsion needs. Mass reduction is particularly crucial for Mars surface landing and liftoff due to the challenges inherent in these operations for even much smaller payloads. In this paper we describe current and planned developments in the area of carbon dioxide removal to support future crewed Mars missions. Activities are also described that apply to both the resolution of anomalies observed in the ISS CDRA and the design of life support systems for future missions
Stromal Expression of miR-143/145 Promotes Neoangiogenesis in Lung Cancer Development
The two unrelated miRNAs miR-143 and miR-145, coexpressed from the miR-143/145 cluster, have been proposed to act as tumor suppressors in human cancer, and therapeutic benefits of delivering miR-143 and miR-145 to tumors have been reported. In contrast, we found that tumor-specific deletion of miR-143/145 in an autochthonous mouse model of lung adenocarcinoma did not affect tumor development. This was consistent with the lack of endogenous miR-143/145 expression in normal and transformed lung epithelium. Surprisingly, miR-143/145 in the tumor microenvironment dramatically promoted tumor growth by stimulating the proliferation of endothelial cells. Loss of miR-143/145 in vivo led to derepression of the miR-145 target CAMK1D, an inhibitory kinase, which when overexpressed prevents mitotic entry of endothelial cells. As a consequence, tumors in miR-143/145-deficient animals exhibited diminished neoangiogenesis, increased apoptosis, and their expansion was limited by the tumor’s ability to co-opt the alveolar vasculature. These findings demonstrate that stromal miR-143/145 promotes tumorigenesis and caution against the use of these miRNAs as agents in cancer therapeutics.SIGNIFICANCE: This study shows that miR-143/145 expressed from the tumor microenvironment stimulates neoangiogenesis and supports tumor expansion in the lung, demonstrating a surprising role for the putative tumor suppressor miRNA cluster in promoting tumorigenesis. We propose inhibition of miR-143/145 as a therapeutic avenue to modulate tumor neoangiogenesis.National Institutes of Health (U.S.) (Grant P01-CA42063-26)National Cancer Institute (U.S.) (Grant P30-CA14051
A comparative study between dry needling verses shockwave therapy on peroneal trigger points in patients with a history of chronic inversion ankle sprain
Abstract: Purpose: The aim of this study was to explore the comparative effects of two different soft tissue approaches in the treatment of active peroneal trigger points. The data from the two different groups was analyzed to establish which soft tissue approach was the most effective in the treatment of active peroneal trigger points in a patient with a history of a chronic inversion ankle sprain. Method: This clinical trial was a quantitative, randomized study that was comparative in nature, of which 30 male and female participants between the ages 18 to 35 years o ld were recruited. This study used the stratification method of randomization according to age and gender. Upon meeting the criteria, participants were divided as they were recruited into two smaller groups of fifteen. Group A received dry needling while group B received shockwave therapy to the most active trigger point in the peroneal muscle group on the side of the chronic inversion ankle sprain. Treatment sessions were carried out over three weeks on alternate days with treatment proceeding on days 1 through 6. Perceived pain was measured using the NPRS, tenderness of the most active peroneal trigger point was measured using the pressure algometer and ankle range of motion was measured using the goniometer on visits 1, 4 and 7. Results: The analysis of Numerical Pain Rating Scale revealed a statistical significance. This indicates that both groups have significance clinically, as both groups were effective in decreasing perceived pain. As was the case with the analysis of the pain pressure algometer readings, both groups revealed a statistical significance, indicating that both groups have significance clinically, as both groups were effective in decreasing pain threshold. However, neither group showed a superior result in reducing perceived pain and pain threshold. As for range of motion, dry needling proved to have a clinical significance as group A yielded the superior results, showing an increase in ankle dorsiflexion, plantarflexion and inversion. Contrary, shockwave therapy proved to be clinically insignificant as there was only an increase in ankle inversion noted. Conclusion: To conclude, both treatment protocols were effective in reducing pain of the active peroneal trigger point. However, dry needling showed to be more effective than shockwave therapy in improving the overall range of motion of the ankle of participants who have a history of a chronic inversion ankle sprain.M.Tech. (Chiropractic
Defying Categorization: Stray Objects and Women’s Material Practices in Nineteenth-Century Fiction
This dissertation engages nineteenth century material objects that fall outside of established categorization and those objects’ associations with contemporary, women-authored texts. A common link between these “stray objects”—be they historical stitched sampler or fictional prized necklace—is their seemingly disruptive applications that both perpetuate and overturn widespread practices. Each chapter of this dissertation focuses on a feminine craft or possession and how the metonymic histories of these objects reify their traditional application and transcend categories to construct new subjectivities or exploit widespread ideologies. Following stray examples of needlecraft, gemstones, glass, and birds reveals the complicated means through which women engaged in material practices, resisted or repurposed objectification, or positioned themselves in spheres outside the domestic realm. Most importantly, these objects signify women’s connection to the nineteenth-century world in ways innumerable: as entwined with colonial meanings, subject to problematic domestication, and connected to animal ecologies. Following these strays is crucial to future scholarship, as they not only preserve historical and cultural archives, but they also provide additional glimpses into women’s complex roles within the said archives. To recover these stray objects is to re-envision the role of objects as foci of rich cultural connections and subjectivities
The role of the saxophone embouchure in the production of the South African jazz sound : a study of nine jazz saxophone players
South Africa is known for having its own distinctive jazz music sound of which the saxophone is a significant feature. The saxophone has often been recognised world-wide as a symbolic jazz instrument and has also played an important role in South African jazz. As the embouchure of the saxophone is crucial to its sound production, it stands to reason that it plays a role in producing this distinctive South African jazz sonority. The purpose of this study is to understand the role of the embouchure in producing the ‘South African jazz saxophone sound’, and to find a common trend in saxophonists
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