Wildlife tourism, science and actor network theory

Wildlife tourism is an important component of tourism worldwide. However, for many species little is known about the possible impacts from tourist-wildlife interactions. Previous research has identified barriers to such science being undertaken but this science-wildlife tourism interface remains poorly understood. Actor-network theory, with its attention to the actors and relationships that make science possible, was used to describe and analyze the development and decline of scientific research into the effects of tourism on wildlife in the Antarctic region. This study concludes that actor-network theory provides a robust description of the complex role and positioning of science in wildlife tourism, while at the same time suggesting that further attention to actors' relative power and scientists' normative beliefs are essential elements of analysis

Implantable RF-coiled chip packaging

In this paper, we present an embedded chip integration technology that utilizes silicon housings and flexible parylene radio frequency (RF) coils. As a demonstration of this technology, a flexible parylene RF coil has been integrated with an RF identification (RFID) chip. The coil has an inductance of 16 μH, with two layers of metal completely encapsulated in parylene-C. The functionality of the embedded chip is verified using an RFID reader module. Accelerated-lifetime soak testing has been performed in saline, and the results show that the silicon chip is well protected and the lifetime of our parylene-encapsulated RF coil at 37 °C is more than 20 years

Synthetic metallomolecules as agents for the control of DNA structure

This tutorial review summarises B-DNA structure and metallomolecule binding modes and illustrates some DNA structures induced by molecules containing metallic cations. The effects of aquated metal ions, cobalt amines, ruthenium octahedral metal complexes, metallohelicates and platinum complexes such as cis-platin are discussed alongside the techniques of NMR, X-ray crystallography, gel electrophoresis, circular dichroism, linear dichroism and molecular dynamics. The review will be of interest to people interested in both DNA structure and roles of metallomolecules in biological systems

Making postgraduate students and supervisors aware of the role of emotions in the PhD process

Emotions are an integral part of the PhD process. A range of emotions are common and to be expected. How do emotions affect the PhD process for both postgraduate students and their supervisors? How can we make our emotions work positively for us in the PhD process? To explore answers to these questions, three lecturers currently supervising postgraduates and three postgraduates at various stages in their doctoral studies collectively pooled their experiences. We developed an interactive workshop that was recently conducted for postgraduate students at Murdoch University and at the Australian Association for Social Research annual conference 2002. This presentation will explore the role that emotions play in the PhD process and how supervisors and postgraduates alike can benefit from reflecting on this issue. A number of practical (and humorous) tips will be provided as well as examples from others' PhD experiences. The role of emotions at the beginning, middle and end of a PhD program will be explored. The data collection and analysis phases are a time when emotions may run riot. Trepidation is especially common when fieldwork or data collection is involved, as is anger when postgraduate's views about how the world works are challenged and then sadness (and relief!) when the data collection phase is finished. We will discuss how supervisors can assist their postgraduates to make these feelings work for them. The presentation will also explore the emotions that arise from the supervisor-postgraduate partnership

Expand+Functional selection and systematic analysis of intronic splicing elements identify active sequence motifs and associated splicing factors

Despite the critical role of pre-mRNA splicing in generating proteomic diversity and regulating gene expression, the sequence composition and function of intronic splicing regulatory elements (ISREs) have not been well elucidated. Here, we employed a high-throughput in vivo Screening PLatform for Intronic Control Elements (SPLICE) to identify 125 unique ISRE sequences from a random nucleotide library in human cells. Bioinformatic analyses reveal consensus motifs that resemble splicing regulatory elements and binding sites for characterized splicing factors and that are enriched in the introns of naturally occurring spliced genes, supporting their biological relevance. In vivo characterization, including an RNAi silencing study, demonstrate that ISRE sequences can exhibit combinatorial regulatory activity and that multiple trans-acting factors are involved in the regulatory effect of a single ISRE. Our work provides an initial examination into the sequence characteristics and function of ISREs, providing an important contribution to the splicing code

Corrosion Behavior of Parylene-Metal-Parylene Thin Films in Saline

In this paper, we study the corrosion behavior of parylene-metal-parylene thin films using accelerated-lifetime soak tests. The samples under test are thin film resistors with a 200 nm layer of Au sandwiched by parylene-C on both sides, fabricated with parylene-metal skin technology. The samples are tested in hot saline both passively and actively, and different failure modes are observed using optical and electron-beam metrologies. Bubbles and delamination are first seen in the samples after 2 days of soaking under passive conditions, and followed by metal corrosion. While under active conditions, either bubbles or parylene breakdowns are observed depending on the thickness of parylene packaging. These results contribute to a better understanding of the failure mechanisms of parylene packaging in body fluids

A Practical Model for Teaching Supervision Through Vertically Integrated Teams

Teaching supervision is a relatively new practice and training area (Schindler and Talen, 1996). This paper describes a method of teaching clinical supervision to graduate students in clinical psychology. The method involves an intensive seminar, assigned readings, and a year long supervised practicum in providing supervision. Students in the first through fourth years of a doctoral program are assigned to a team with a faculty leader. The faculty member oversees the professional development of all students on the team. Additionally, the fourth year students oversee the first and second year students under the supervision of the faculty member. This method facilitates the initial development of supervisory skills in students prior to their internship. Training in supervision is thought to be important because many psychologists function as supervisors and the demand for supervision by clinical psychologists may be rising with current changes in the health care delivery system

Antimicrobial activity of an iron triple helicate

The prevalence of antibiotic resistance has resulted in the need for new approaches to be developed to combat previously easily treatable infections. Here we investigated the potential of the synthetic metallomolecules [Fe2L3]4+ and [Cu2(L’)2]2+ as antibacterial agents. Both molecules have been shown to bind DNA; [Fe2L3]4+ binds in the major groove and causes DNA coiling, whilst [Cu2(L’)2]2+ can act as an artificial nuclease. The work described here shows that only [Fe2L3]4+ is bactericidal for Bacillus subtilis and Escherichia coli. We demonstrate that [Fe2L3]4+ binds bacterial DNA in vivo and, strikingly, that it kills B. subtilis cells very rapidly