Regulation of the renal sympathetic nerves in heart failure

Heart failure (HF) is a serious debilitating condition with poor survival rates and an increasing level of prevalence. Heart failure is associated with an increase in renal norepinephrine spillover, which is an independent predictor of mortality in HF patients. The excessive sympatho-excitation that is a hallmark of heart failure has long-term effects that contribute to disease progression. An increase in directly recorded renal sympathetic nerve activity has also been recorded in animal models of heart failure. This review will focus on the mechanisms controlling sympathetic nerve activity to the kidney during normal conditions and alterations in these mechanisms during heart failure. In particular the roles of afferent reflexes and central mechanisms will be discussed

Transmission system regularization with 5-level cascaded IPFC

In recent years, there is an immensely huge demand to power due to industrialization and modernization, butcorrespondingly the amplification of generation and transmission has not been done due to constrained resources and environmental limitations. The huge growth in demand leads to various problems in power systems. Heavy growth in semiconductor technology made power electronics plays a key role in solving these problems. Flexible AC transmission system (FACTS) devices are used for fixing various problems in power system. They are used for enhancing the existing transmission capabilities and improving the system dynamic performance so that to make transmission system flexible and efficient in operation. Inter line power flow controller (IPFC) is a latest generation series connected FACTS device, having capability of controlling power flow among multi line in a transmission network. In this paper cascaded 5 level inverter is used as the inverter module for IPFC. Control techniques play a vital role in power flow control in the system, with the main objective of minimization of harmonics and obtaining a variable output with maximum fundamental component. This paper discusses various comparative case studies on IPFC with cascaded 5 level inverter using SPWM and SVM control techniques

Deterministic Chaos in Blood Pressure Signals During Different Physiological Conditions

Several coupled and nonlinear controlling mechanisms are involved in the regulation of blood pressure. The possible presence of chaos in physiological signals has been the subject of some research. In this study, blood pressure signals were analysed using a range of nonlinear time series analysis techniques. Individual effectors of blood pressure were either experimentally removed or enhanced, so that the controlling mechanisms that are responsible for the chaotic nature of the signals may be identified by chaotic analysis of the signals. The level of chaos varied across the different experimental conditions, showing a distinct decrease from control conditions to all other experimental conditions

Deterministic Chaos in Blood Pressure Signals During Different Physiological Conditions

Several coupled and nonlinear controlling mechanisms are involved in the regulation of blood pressure. The possible presence of chaos in physiological signals has been the subject of some research. In this study, blood pressure signals were analysed using a range of nonlinear time series analysis techniques. Individual effectors of blood pressure were either experimentally removed or enhanced, so that the controlling mechanisms that are responsible for the chaotic nature of the signals may be identified by chaotic analysis of the signals. The level of chaos varied across the different experimental conditions, showing a distinct decrease from control conditions to all other experimental conditions

The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis

Background: The development of digital technologies and the evolution of open innovation approaches have enabled the creation of diverse virtual organizations and enterprises coordinating their activities primarily online. The open innovation platform titled "International Natural Product Sciences Taskforce" (INPST) was established in 2018, to bring together in collaborative environment individuals and organizations interested in natural product scientific research, and to empower their interactions by using digital communication tools. Methods: In this work, we present a general overview of INPST activities and showcase the specific use of Twitter as a powerful networking tool that was used to host a one-week "2021 INPST Twitter Networking Event" (spanning from 31st May 2021 to 6th June 2021) based on the application of the Twitter hashtag #INPST. Results and Conclusion: The use of this hashtag during the networking event period was analyzed with Symplur Signals (https://www.symplur.com/), revealing a total of 6,036 tweets, shared by 686 users, which generated a total of 65,004,773 impressions (views of the respective tweets). This networking event's achieved high visibility and participation rate showcases a convincing example of how this social media platform can be used as a highly effective tool to host virtual Twitter-based international biomedical research events

Anisotropic properties and behaviours of carbon sequestrated 3D printed concrete

The construction industry is under increasing pressure to reduce its carbon footprint while maintaining structural integrity and performance. This project investigates an innovative approach to 3D printed concrete (3DCP) by integrating CO₂-Steam technology with Polyethylene Glycol (PEG) reinforcement. The primary objectives are to enhance the mechanical performance of 3DCP and to assess its potential for carbon sequestration and decarbonization. The study employs a comprehensive experimental and numerical framework. The concrete mixes are modified by incorporating different concentrations of PEG (0%, 1%, 2%, and 3%), and half of the samples are subjected to CO₂ treatment (CO₂-Steam Integration into the printing Process.) Testing protocols include flexural, compressive, and interlayer bonding assessments at curing durations of 7 and 28 days. These tests are designed to capture the inherent anisotropic behaviour of 3DCP, particularly the directional dependencies associated with the layered manufacturing process. Notably, while PEG significantly enhances in-layer properties through improved internal curing and moisture retention, its ability to reinforce the weak interlayer interfaces is limited due to fibre confinement within individual layers. Numerical simulations are conducted using ABAQUS, where the Concrete Damaged Plasticity (CDP) model is augmented with cohesive zone modelling (CZM) to accurately replicate the nonlinear behaviour of the composite material. This integrated approach provides a robust framework for evaluating the performance of 3DCP under varied loading conditions and offers insights into the interplay between material composition, curing conditions, and structural anisotropy. Overall, this research advances our understanding of sustainable 3D printed concrete and contributes valuable insights into the integration of carbon sequestration technologies within the construction industry, paving the way for more environmentally friendly and structurally efficient building practices.Master's degre