ESPACIOS, TRADICIONES Y CAMBIOS EN CONCHUCOS. Ecos desde la Escuela de etnografía del Proyecto “Antonio Raimondi”, Ancash Perú

Este volumen nace con dos finalidades precisas. La primera, dar a conocer los trabajos de investigación etnográfica que un grupo de nueve estudiantes de la Universidad de Bologna (Italia) y otro de la Pontificia Universidad Católica del Perú han desarrollado en la provincia de Huari, Ancash, Perú, durante seis años, entre 2003 y 2008 en el marco del Proyecto Arqueológico y Antropológico “Antonio Raimondi”. La segunda finalidad es realizar la difusión de las únicas miradas etnográficas que hasta hoy se han producido sobre la región Conchucos. Otro objetivo, más teórico y más implícito, es desplegar a lo largo del camino de la lectura de los casos etnográficos, una visión processual y dinamista de la escritura etnográfica y de la especulación antropológica, procedente de una manera precisa de hacer trabajo de campo. Los artículos aquí propuestos presentan, mediante varios estilos y diferentes acercamientos, una realidad sociocultural en movimiento, en constante cambio. Construyendo cuadros de varios aspectos sociales, políticos y culturales de la provincia de Huari, los autores delinean un escenario en proceso en el cual diferentes actores, ámbitos y dinámicas socioculturales se interrelacionan, participando de maneras diferents en la transformación

Experimental data and simulations of performance and thermal comfort in a patient room equipped with radiant ceiling panels

Hospitals require the highest energy demands in non-residential buildings. They provide healthcare 24/7/365 and, at the same time, they ensure indoor air quality, thermal comfort and sterility. However, several studies reveal that high indoor temperatures and low relative humidity (RH) are often perceived in patient rooms during the heating season, suggesting an important energy saving potential. Against this background, radiant ceiling panel (RCP) systems result to be one of the most appropriate solutions as they allow to achieve significant energy savings while providing the highest level of thermal and acoustic comfort, as well as of infection control. In the present study the microclimatic survey of a patient room at Maggiore Hospital in Bologna, Italy, equipped with an air conditioning system integrated with RCP, has reported occupant thermal discomfort. Experimental data were used to calibrate a building model and dynamic building energy simulations were carried out to analyse indoor air temperature, relative humidity, predicted mean vote (PMV) and predicted percentage of dissatisfied (PPD) indexes under different inlet air temperatures, to identify the best design conditions for energy efficiency and thermal comfort improvement. It was found that the highest advantages can be obtained when neutral air is supplied

A Simplified Thermal Plasto-Elastohydrodynamic Lubrication Model for Circular Contact With Real Surface Roughness

The current increase in power density, contact load, and speeds have imposed new challenges on elastohydrodynamic lubrication (EHL) contact models. To overcome possible EHL limitations under such conditions, the present work presents a unified thermal plasto-elastohydrodynamic lubrication (TPEHL) model for circular contact with real surface roughness capable to simulate the different lubrication regimes. Among the main characteristics of the proposed model, one should mention the minimal implementation changes in standard EHL models; there is no need for a preliminary assessment to verify whether thermal and plastic effects are negligible (or not) since these effects will naturally take place in the simulations, and good agreement between the predictions using the model and the experimental measurements

Guillain-Barré syndrome and adjuvanted pandemic influenza A (H1N1) 2009 vaccines: A multinational self-controlled case series in Europe

Background: The risk of Guillain-Barré syndrome (GBS) following the United States' 1976 swine flu vaccination campaign in the USA led to enhanced active surveillance during the pandemic influenza (A(H1N1)pdm09) immunization campaign. This study aimed to estimate the risk

Operando Optical Microscopy of Dead Lithium Growth in Anode-Less Configuration

There is an increasing demand to improve battery safety and performance as part of the global push to convert the small electronics and transportation sector to infrastructures based on electricity. This work follows the deposition of lithium metal in anode-less conditions by an operando optical microscope using a transparent indium tin oxide-polyethylene terephthalate (ITO-PET) window as the current collector in a readily-available electrochemical set-up. The mechanism of Li metal nucleation strongly depends on the selected current densities (C/40 and 2C). After the deposition of the solid electrolyte interface (SEI), Li nucleates from mossy to needle morphology. Moreover, layer-by-layer growth of dead Li in voids is monitored by following its accumulation upon cycling. Dead Li deposits in residual hollow structures, especially when high current densities are applied. These optical observations are coupled with computer vision analyses to evaluate the average size of the Li deposits: smaller Li nuclei plate when high C-rate is applied. The results here described provide insights into a new electrochemical cell concept that enables to elucidate the influence of spatial inhomogeneities of the lithophilic ITO-PET surface on the mechanism of Li nucleation and plating

Guillain-Barré syndrome and adjuvanted pandemic influenza A (H1N1) 2009 vaccine: multinational case-control study in Europe

Objective To assess the association between pandemic influenza A (H1N1) 2009 vaccine and Guillain-Barré syndrome

Optimizing Current Collector Interfaces for Efficient “Anode-Free” Lithium Metal Batteries

Current lithium (Li)-metal anodes are not sustainable for the mass production of future energy storage devices because they are inherently unsafe, expensive, and environmentally unfriendly. The anode-free concept, in which a current collector (CC) is directly used as the host to plate Li-metal, by using only the Li content coming from the positive electrode, could unlock the development of highly energy-dense and low-cost rechargeable batteries. Unfortunately, dead Li-metal forms during cycling, leading to a progressive and fast capacity loss. Therefore, the optimization of the CC/electrolyte interface and modifications of CC designs are key to producing highly efficient anode-free batteries with liquid and solid-state electrolytes. Lithiophilicity and electronic conductivity must be tuned to optimize the plating process of Li-metal. This review summarizes the recent progress and key findings in the CC design (e.g. 3D structures) and its interaction with electrolytes

Hexavalent Ions Insertion in Garnet Li7La3Zr2O12 Toward a Low Temperature Densification Reaction

Nowadays, solid electrolytes are considered the main alternative to conventional liquid electrolytes in lithium batteries. The fabrication of these materials is however limited by the strict synthesis conditions, requiring high temperatures which can negatively impact the final performances. Here, it is shown that a modification of garnet-based Li7La3Zr2O12 (LLZO) and the incorporation of tellurium can accelerate the synthesis process by lowering the formation temperature of cubic LLZO at temperatures below 700 °C. Optimized synthesis at 750 °C showed a decrease in particle size and cell parameter for samples with higher amounts of Te and the evaluation of electrochemical performances reported for LLZO Te0.25 a value of ionic conductivity of 5,15×10−5 S cm−1 after hot-pressing at 700 °C, two orders of magnitude higher than commercial Al-LLZO undergoing the same working conditions, and the highest value at this densification temperature. Partial segregation of Te-rich phases occurs for high-temperature densification. Our study shows the advantages of Te insertion on the sintering process of LLZO garnet and demonstrates the achievement of highly conductive LLZO with a low-temperature treatment

SNAI1-expressing fibroblasts and derived-extracellular matrix as mediators of drug resistance in colorectal cancer patients

of colorectal cancer (CRC) patients. Cancer-Associated Fibroblasts (CAFs) are the main producers and remodelers of the extracellular matrix (ECM), which is directly involved in drug resistance mechanisms. Primary Normal Fibroblasts (NFs) and CAFs and cell lines (fibroblasts and tumor cells), were used to generate ECM and to identify its role in the oxaliplatin and cetuximab chemoresistance processes of CRC cells mediated by SNAI1-expressing fibroblasts. Matrices generated by Snai1 KO MEFs (Knockout Mouse Embryonic Fibroblasts) confer less resistance on oxaliplatin and cetuximab than wild-type MEF-derived matrices. Similarly, matrices derived from CAFs cause greater survival of colorectal cancer cells than NF-derived matrices, in a similar way to Snai1 expression levels. In addition, Snail1 expression in fibroblasts regulates drug resistance and metabolism gene expression in tumor cells mediated by ECM. Finally, a series of 531 patients (TCGA) with CRC was used to assess the role of SNAI1 expression in patients' prognosis indicating an association between tumor SNAI1 expression and overall survival in colon cancer patients but not in rectal cancer patients. SNAI1 expression in CRC cancer patients, together with in vitro experimentation, suggests the possible use of SNAI1 expression in tumor-associated fibroblasts as a predictive biomarker of response to oxaliplatin and cetuximab treatments in patients with CRC