Screening polyoxometalates as aquaporin inhibitors for cancer therapeutics

Aquaporins (AQPs) are transmembrane protein channels that facilitate the diffusion of water and glycerol across cell membranes, crucial for water and energy homeostasis. These proteins were found overexpressed in different cancer cells and tissues, being involved in cell proliferation and migration, tumor formation, and angiogenesis, suggesting their great potential as novel drug targets for cancer treatment. Identification of potent and selective aquaporin inhibitors to be used in cancer therapeutics is of utmost importance. Polyoxometalates (POMs) are transition metal complexes that exhibit a broad diversity of structures and properties.info:eu-repo/semantics/publishedVersio

AIDS im Südlichen Afrika : die sozialen Folgen einer Epidemie

Seit fast 20 Jahren gibt es am Institut für Soziologie einen Afrika-Schwerpunkt. Seit April letzten Jahres fördert die Deutsche Forschungsgemeinschaft ein Projekt dieses Schwerpunkts, das sich mit den sozialen Folgen von AIDS im Südlichen Afrika befasst. In verschiedenen Regionen der Länder Botswana und Namibia werden in dem Projekt mit Methoden der qualitativen Sozialforschung die gesellschaftlichen Auswirkungen der \u27modernen Krankheit\u27 nachgezeichnet

The biological applications of metals and metal complexes

Over the course of biological evolution, approximately 25 to 30 elements have been recognized as essential for the proper functioning of biological systems since the emergence of life [...]LA/P/0101/2020info:eu-repo/semantics/publishedVersio

Duitschland en Engeland

leyds-60-7301.pdf created from original pamphlet in the WJ Leyds Collection held in the Africana Section of the Stellenbosch University Library and Information Service.Dutch pamphlet describing the attitude of Germany and England towards the Z.A.R

Techniques for computing with low-independence randomness

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1990.Includes bibliographical references (p. 105-110).by John Taylor Rompel.Ph.D

Waarom nie beter musiek in ons bioskope nie?

Criticizes the poor quality of music heard in the cinemas before performances and during intervals, be it live music or recordings.Digitized version of an article that appeared in Die Brandwag of 8 Oct. 1937.Inset: short article on Gary Cooper with portrait.pm201