256 research outputs found
Zuwanderung, Demografie und Arbeitsmarkt: Fakten statt Vorbehalte
Die öffentliche Debatte um Zuwanderung und Integration wird auch heute, ein halbes Jahrhundert nach dem Beginn der neueren Immigrationsgeschichte der Bundesrepublik, noch oft unsachlich geführt. Über die durchweg positiven Erfahrungen mit den ökonomischen Zusammenhängen von Migration, Arbeitsmarkt und Sozialstaat ist zu wenig allgemein bekannt, ebenso über die Vorteilhaftigkeit einer bedarfsorientierten Steuerung der Zuwanderung. Stattdessen finden populistische Thesen rund um eine vermeintlich zum Scheitern verurteilte Zuwandererintegration Widerhall, während zugleich eine ökonomische Kurskorrektur der Zuwanderungspolitik vielfach Skepsis hervorruft. Dieser Beitrag greift verbreitete Vorbehalte gegen Zuwanderung auf und widerlegt sie im Licht internationaler wissenschaftlicher Erkenntnisse. Eine gezielte Öffentlichkeitsarbeit „pro“ Zuwanderung kann und muss Vorbehalten durch klare Fakten begegnen. Dabei sollte dreierlei verdeutlicht werden: (1) Zuwanderung qualifizierter Arbeitskräfte bringt generell klare ökonomische Vorteile. (2) Obwohl in Deutschland bislang eher passiv hingenommen denn aktiv gestaltet, fällt auch die Bilanz für die jüngere deutsche Zuwanderungsgeschichte per Saldo günstig aus. (3) Mit den Mitteln einer aktiven und dabei steuernden Zuwanderungspolitik kann dafür gesorgt werden, dass künftig die Arbeitsmarktbelange bei der Entscheidung über Einwanderungsgenehmigungen stärker Beachtung finden. Dies wird die Wohlfahrtsvorteile durch Zuwanderung weiter vergrößern und ist ein wichtiges Fundament für eine noch größere Akzeptanz der Migranten in unserer Gesellschaft.Demografischer Wandel, Punktesystem, Auswahlverfahren für Zuwanderer, Ungleichheit, Integration, Arbeitsmigration, Zuwanderungspolitik
Placebo-controlled manipulations of testosterone levels and dominance
Mazur & Booth present an intriguing model of the relationship between circulating testosterone levels and dominance behaviour in man, but their review of studies on testosterone–behaviour relationships in man is selective. Much of the evidence they cite is correlational in nature. Placebo-controlled manipulations of testosterone levels are required to test their hypothesis that dominance levels are testosterone-dependent in man. The changes in testosterone level that follow behavioural experience may be a consequence of stress. Testosterone levels in man are determined by a wide variety of factors, and a multivariate approach is required
Neuropsychological Aspects of Liver Disease and its Treatment
Liver disease can lead to serious impairment in cognitive functioning, through the development of a condition known as hepatic encephalopathy (HE). While gross impairment is clinically obvious, milder variants of the condition may escape detection at bedside examination and yet may have a significant impact on day-to-day activities. In this brief review article, the neuropsychology of liver disease is examined, focusing on nature, aetiology and significance. The possible contributory role of endogenous benzodiazepines in HE is described, as is the evidence regarding the effect of benzodiazepine antagonism on cognitive functioning in HE. The functional localisation of HE is briefly reviewed, as is the use of neuropsychological measures to evaluate treatment efficacy, e.g. following shunt procedures or liver transplantation. Finally, living donor liver transplantation is described, and the case is made for rigorous longitudinal neuropsychological evaluation of potential donors and recipients
The impact of personalised risk information compared to a positive/negative result on informed choice and intention to undergo colonoscopy following colorectal Cancer screening in Scotland (PERICCS) - a randomised controlled trial:study protocol
Background In Scotland a new, easier to complete bowel screening test, the Faecal Immunochemical Test (FIT), has been introduced. This test gives more accurate information about an individual’s risk of having colorectal cancer (CRC), based on their age and gender, and could lead to fewer missed cancers compared to the current screening test. However, there is no evidence of the effect on colonoscopy uptake of providing individuals with personalised risk information following a positive FIT test. The objectives of the study are: 1) To develop novel methods of presenting personalised risk information in an easy-to-understand format using infographics with involvement of members of the public 2) To assess the impact of different presentations of risk information on informed choice and intention to take up an offer of colonoscopy after FIT 3) To assess participants’ responses to receiving personal risk information (knowledge, attitudes to screening/risk, emotional responses including anxiety). Methods Adults (age range 50–74) registered on the Scottish Bowel Screening database will be invited by letter to take part. Consenting participants will be randomised to one of three groups to receive hypothetical information about their risk of cancer, based on age, gender and faecal haemoglobin concentration: 1) personalised risk information in numeric form (e.g. 1 in 100) with use of infographics, 2) personalised information described as ‘highest’, ‘moderate’ or ‘lowest’ risk with use of infographics, and 3) as a ‘positive’ test result, as is current practice. Groups will be compared on informed choice, intention to have a colonoscopy, and satisfaction with their decision. Follow-up semi-structured qualitative interviews will be conducted, by telephone, with a small number of consenting participants (n = 10 per group) to explore the acceptability/readability and any potential negative impact of the risk information, participants’ understanding of risk factors, attitudes to the different scenarios, and reasons for reported intentions. Discussion Proving personalised risk information and allowing patient choice could lead to improved detection of CRC and increase patient satisfaction by facilitating informed choice over when/whether to undergo further invasive screening. However, we need to determine whether/how informed choice can be achieved and assess the potential impact on the colonoscopy service
Behavioural effects of androgens in men
A series of studies are presented which attempt to answer specific
questions concerning the androgen-behaviour relationship in the adult
human male.
A critical review of the literature revealed that the
androgen-behaviour relationship in the human male has been poorly
researched. In particular, unsatisfactory experimental methodology and
inexact operational definitions of behaviour have been employed. In
the studies presented in this thesis an attempt was made to
specifically define dysfunctional states and to carefully monitor the
resultant behavioural effects of androgen administration.
In the hypogonadal man, a dose-dependent relationship was
demonstrated for specific aspects of sexual functioning, in particular
self-rated interest in sex and frequency of morning erections appeared
to vary with androgen replacement dose.
In the eugonadal man, intramuscular depot injections of
testosterone were shown to be the best method of overcoming the
homeostatic mechanisms and increasing circulating androgen levels in
the blood. High dosage testosterone administration acted to increase the
level of sexual interest of a group of men whose presenting complaint
was loss of libido. This treatment, however, did not result in an
increased frequency of sexual activity. High dosage testosterone
administration had no behavioural effect, compared with placebo, in a
group of eugonadal men presenting with erectile dysfunction.
Androgen administration appeared to have a stimulatory effect on
the nocturnal erections of a group of hypogonadal men, although androgen withdrawal resulted in differing rates of diminution of
nocturnal erectile response. In contrast, androgen administration had
no effect on the nocturnal erections of a group of eugonadal men
presenting with erectile dysfunction.
Androgen administration to hypogonadal and eugonadal men had a
general lack of effect on a series of psychometric test scores, which
measure various aspects of cognitive functioning and personality.
(Previous investigators had proposed that these test scores were
correlated with circulating androgen levels).
A case study is presented, reporting the lack of behavioural
effect of oral testosterone undecanoate administration in an
institutionalised hypogonadal man who had previously responded very
aggressively to testosterone injections.
The implications of these experimental findings are discussed in
relation to the results of previous studies
Medication adherence across the lifespan: Theory, methods, interventions and six grand challenges
First paragraph: Taking medication as agreed with a health care provider ‘i.e. adherence’, is a critically important health behaviour throughout life for both the prevention and treatment of illness and the maintenance of health (Osterberg & Blaschke, 2005). From childhood use of antibiotics (Baguley, Lim, Bevan, Pallet, & Faust, 2012), to early adulthood use 15 of oral contraceptives (Molloy, Graham, & McGuinness, 2012) to older adulthood use of cardiovascular risk reduction medications (O’Carroll, Chambers, Dennis, Sudlow, & Johnston, 2014), evidence-based treatments such as these can have profound impact on health across the lifespan. Variability in the initiation, execution and persistence of med- ication taking behaviour plays a significant role in explaining the difference between 20 the trial-based efficacy and ‘real-world’ effectiveness for many medications (Blaschke, Osterberg, Vrijens, & Urquhart, 2012). Medication adherence has therefore been the focus of systematic investigation for several decades by both behavioural and clinical scientists (DiMatteo, 2004).Output Type: Editoria
Neuropsychological functioning, illness perception, mood and quality of life in chronic fatigue syndrome, autoimmune thyroid disease and healthy participants
Background This study attempted to longitudinally investigate neuropsychological function, illness representations, self-esteem, mood and quality of life (QoL) in individuals with chronic fatigue syndrome (CFS) and compared them with both healthy participants and a clinical comparison group of individuals with autoimmune thyroid disease (AITD). Method Neuropsychological evaluation was administered at two time points, five weeks apart. Twenty-one individuals with CFS, 20 individuals with AITD and 21 healthy participants were matched for age, pre-morbid intelligence, education level and socio-economic status (SES). All groups also completed measures of illness perceptions, mood, self-esteem and QoL at both time points. Results The CFS group showed significantly greater impairment on measures of immediate and delayed memory, attention and visuo-constructional ability, and reported significantly higher levels of anxiety and depression. After controlling for the effects of mood, the CFS group still demonstrated significant impairment in attention. The CFS group also reported significantly lower self-reported QoL than the AITD and healthy participants. In terms of illness perceptions, the AITD group believed that their condition would last longer, that they had more treatment control over their condition, and reported less concern than the CFS group. Conclusions These results suggest that the primary cognitive impairment in CFS is attention and that this is not secondary to affective status. The lower treatment control perceptions and greater illness concerns that CFS patients report may be causally related to their affective status
'What if I'm not dead?' - Myth-busting and organ donation
Objectives. In the UK, three people die every day awaiting an organ transplant. To address this, Scotland and England plan to follow Wales and introduce opt-out donor consent. However, emotional barriers, myths and misconceptions may deter potential registrants. Our objectives were to estimate the number of people who plan to opt-out of the donor register and to test if emotional barriers (e.g., medical mistrust) differentiated participants within this group. Finally, in an experimental manipulation, we tested whether intention to donate decreased by making emotional barriers more salient and increased following a widely used myth-busting intervention. Design. Mixed between-within design. Methods. UK residents (n = 1202) were asked whether they would choose; opt-in, deemed consent, or opt-out/not sure if legislation changes to opt-out. Participants also completed measures of donor intentions at baseline, following a 12-item emotional barriers questionnaire and again, following a 9-item myth-busting intervention. Results. Findings indicate that 66.1% of participants selected to opt-in to the donor register, 24.3% selected deemed consent and 9.4% selected opt-out/not sure. Emotional barriers, notably, fears surrounding bodily integrity were significantly elevated in participants who selected opt-out/not sure. Increasing the salience of emotional barriers reduced donor intentions in the opt-out/not sure group. However, dispelling organ donation myths did not increase intention within this group. Conclusions. If opt-out legislation is introduced in Scotland and England, approximately 10% of participants plan to opt-out or are not sure. Dispelling organ donation myths with facts may not be the best method of overcoming emotional barriers and increasing donor intentions for those planning to opt-out
The relative importance of avoidance and restoration-oriented stressors for grief and depression in bereaved parents
Previous research has identified a number of individual risk factors for parental bereavement including the sex of the parent, the sex of the child, avoidance-focussed coping style and time since death. These factors emerged from research where variables were tested univariately and their relative importance is currently unknown. The current research, therefore, aims to investigate which risk factors are important, multivariately, for the outcomes of grief and depression in parents following the death of their child. Psychosocial measures were completed by 106 bereaved parents four years post-loss, recruited from death records in Scotland. The cause of the child's death included long-term illness and stillbirths as well as sudden and violent deaths. In multivariate regression analyses, depression was predicted by higher avoidance- focussed coping and higher number of restoration-oriented stressors such as relationship difficulties, problems at work and financial issues. Grief was predicted by higher avoidance, restoration stressors and level of continuing bonds. The present study adds to the knowledge about the phenomenon of parental bereavement with participants recruited directly from death records rather than through support, clinical or obituary sources. Factors previously found to be associated with outcomes when tested univariately such as sudden, violent death or sex of the parent were not significant when tested multivariately. This study highlights that different vulnerability factors exist for grief and depression in bereaved parents
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