18 research outputs found

    Derivation of a statistical model for classical systems obeying fractional exclusion principle

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    The violation of the Pauli principle has been surmised in several models of the Fractional Exclusion Statistics and successfully applied to several quantum systems. In this letter, a classical alternative of the exclusion statistics is studied using the maximum entropy principle. Using an additional restriction in the Maxwell-Boltzmann statistics related to the degree of indistinguishability, it is found that the resulting probability distribution function follows the fractional exclusion principle in dilute conditions. Properties of various variables of this novel statistical model are studied and possible application to classical thermodynamics is discussed.Comment: 6 pages, 1 figur

    Application of Haldane's statistical correlation theory in classical systems

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    This letter investigates the application of Haldane's statistical correlation theory in classical systems. A modified statistical correlation theory has been proposed by including non-linearity in the form of an exponent into the original theory of Haldane. The dependence of the statistical correlation on indistinguishability is highlighted. Using this modified theory, a quasi-classical derivation of intermediate statistics is shown where indistinguishability can be introduced into distinguishable systems in the form of a statistical correlation. The final result is equivalent to the classical fractional exclusion statistics (CFES), which was derived earlier using a purely classical route. An extended non-linear correlation model based on power series expansion is also proposed, which can produce various intermediate statistical models

    Influence of the coordination defects on the dynamics and the potential energy landscape of two-dimensional silica

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    The main cause of the fragile-to-strong crossover of 3D silica was previously attributed to the presence of a low energy cutoff in the potential energy landscape. The important question emerges about the microscopic origin of this crossover and the generalizibility to other glass-formers. In this work, the fragile-to-strong crossover of a model 2D glassy system is analyzed via molecular dynamics simulation, which represents 2D-silica. By separating the sampled defect and defect-free inherent structures, we are able to identify their respective density of state distributions with respect to energy. A low energy cutoff is found in both distributions. It is shown that the fragile-to-strong crossover can be quantitatively related to the parameters of the energy landscape, involving in particular the low-energy cutoff of the energy distribution. It is also shown that the low-energy cutoff of the defect-states is determined by the formation energy of a specific defect configuration, involving two silicon and no oxygen defect. The low-temperature behavior of 2D silica is quantitatively compared with that of 3D silica, showing surprisingly similar behavior.Comment: 11 pages, 7 figure

    Role of Immunological Method of Fecal Occult Blood Test for Screening Colorectal Diseases

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    Background: Colorectal diseases specially colorectal carcinoma is one of the major health problems throughout the world. Therefore, early diagnosis of these diseases is mandatory. There are various screening methods are used for early diagnosis of colorectal diseases. Among them fecal occult blood test is the most widely used screening test. Objectives: The objectives of the present study were to find out the role of immunological method of fecal occult blood test for screening colorectal diseases. Methods: This was a prospective study consisted of 110 patients suspected to have colorectal diseases of both sexes attending in Gastroenterology and Clinical Pathology department of Bangabandhu Sheikh Mujib Medical University. Stool samples of all the patients were examined by immunological method of fecal occult blood test and then advised for colonoscopy and histopathology for confirmatory diagnosis. The results of immunological method of fecal occult blood test and the colonoscopic findings were compared. Results. Of 110 patients, 87 (79%) cases were positive and 23 (20.9%)cases were negative by immunological method of fecal occult blood test. According to colonoscopy and histopathology, 65(32.5%) cases were found to have colorectal diseases and 45(22.5%) cases had no pathology. Diseases detected by colonoscopy in occult blood test positive patients, 18(16.4%) colorectal polyp, 24(21.8%) colonic ulcer, 8(7.3%) colorectal cancer, 5(3.5%) inflammatory bowel disease, 7(6.4%) haemorrhoids and fissure, 2(1.8%) colonic diverticulum and 1(0.9%) proctitis. Among the 65(32.5%) lesions detected by colonoscopy,62(95.3%) cases were positive by immunological method of fecal occult blood test where as only three(3) lesions were found in occult blood test negative cases. The sensitivity, specificity, PPV and NPV of immunological method of fecal occult blood test (IFOBT) for detection of occult bleeding were 95.4%, 44.4%, 71.3% and 87.0% respectively. Conclusion: It can apparently be concluded from this study that the role of immunological method of fecal occult blood test for colorectal diseases is promising in Bangladesh. Key words: Colorectal diseases; Fecal occult blood test; Immunological method DOI: http://dx.doi.org/10.3329/bsmmuj.v4i2.8634 BSMMU J 2011; 4(2):76-8

    Role of Immunological Method of Fecal Occult Blood Test for Screening Colorectal Diseases

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    Background: Colorectal diseases specially colorectal carcinoma is one of the major health problems throughout the world. Therefore, early diagnosis of these diseases is mandatory. There are various screening methods are used for early diagnosis of colorectal diseases. Among them fecal occult blood test is the most widely used screening test. Objectives: The objectives of the present study were to find out the role of immunological method of fecal occult blood test for screening colorectal diseases. Methods: This was a prospective study consisted of 110 patients suspected to have colorectal diseases of both sexes attending in Gastroenterology and Clinical Pathology department of Bangabandhu Sheikh Mujib Medical University. Stool samples of all the patients were examined by immunological method of fecal occult blood test and then advised for colonoscopy and histopathology for confirmatory diagnosis. The results of immunological method of fecal occult blood test and the colonoscopic findings were compared. Results. Of 110 patients, 87 (79%) cases were positive and 23 (20.9%)cases were negative by immunological method of fecal occult blood test. According to colonoscopy and histopathology, 65(32.5%) cases were found to have colorectal diseases and 45(22.5%) cases had no pathology. Diseases detected by colonoscopy in occult blood test positive patients, 18(16.4%) colorectal polyp, 24(21.8%) colonic ulcer, 8(7.3%) colorectal cancer, 5(3.5%) inflammatory bowel disease, 7(6.4%) haemorrhoids and fissure, 2(1.8%) colonic diverticulum and 1(0.9%) proctitis. Among the 65(32.5%) lesions detected by colonoscopy,62(95.3%) cases were positive by immunological method of fecal occult blood test where as only three(3) lesions were found in occult blood test negative cases. The sensitivity, specificity, PPV and NPV of immunological method of fecal occult blood test (IFOBT) for detection of occult bleeding were 95.4%, 44.4%, 71.3% and 87.0% respectively. Conclusion: It can apparently be concluded from this study that the role of immunological method of fecal occult blood test for colorectal diseases is promising in Bangladesh. Key words: Colorectal diseases; Fecal occult blood test; Immunological method DOI: http://dx.doi.org/10.3329/bsmmuj.v4i2.8634 BSMMU J 2011; 4(2):76-8

    Clinical presentation of ulcerative colitis among Bangladeshi population twenty years experience from a tertiary care hospital in Bangladesh

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    Background: The prevalence of Ulcerative colitis has been increasingly reported from Western countries as well as other Asian countries. Our personal experience shows that Ulcerative colitis is not uncommon in our country and is being diagnosed more commonly. So, there is need to study the disease pattern in our country. Objective: To find out the clinical presentation, among Bangladeshi population. Methods: A hospital (Department of Gastroenterology, Bang­abandhu Sheikh Mujib Medical University) based study registering previously diagnosed and newly diagnosed cases of Ulcerative colitis, was carried out from January 1990 to June 2010. Data that were obtained are: age and sex of the patients, clinical presentations like bloody diarrhoea, per rectal bleeding, diarrhoea without per rectal bleeding, urgency, tenesmus, abdominal pain, fever, anorexia, weakness, weight loss. Data regarding physical findings and extra intestinal manifestations were also recorded. Results: Out of 164 patients 65.24% (107) were male and 34.76% (57) were female. The male- female ratio was 1.88 : 1. Mean age of male patients was 36.14(±11.66) years and mean age for female patients was 33.15(±11.12) years. Maximum number of male patients were in 21-40 years age group (65.42%, 70). Maximum number of female patients were in 21-30 years age group (42.10%, 24). Maximum number of both male and female patients were in 21-30 years age group (35.97%, 59). Clinical features of 164 patients showed that 87.28% (143) had bloody diarrhoea, 20.12% (33) had per-rectal bleeding, 4.26% (7) had diarrhoea without per rectal bleeding, 1.21% (2) had urgency, 5.48% (9) had tenesmus, 33.53% (55) had abdominal pain, 17.66% (29) had fever, 18.29% (30) had anorexia, weakness and 17.68% (29) had weight loss at their initial presentation. Physical examination of 164 patients revealed that 81(49.39%) patients had normal findings, 7 (4.27%) patients had oedema and 83 (50.61%) patients had anaemia. Extra intestinal features were absent in 143 (87.20%) patients out of 164 patients. The rest 21 (12.80%) patients had joint involvement and 2 ( 1.21 % ) patients had ocular involvement. There was no patient with skin involvement. Conclusion: The clinical presentation of Ulcerative colitis in our country is mostly similar compared to other Asian' and Western countries except higher male-female ratio, presence of oedema and wide variability of extra intestinal involve­ment. These differences are probably due to social and cultural reasons, poor nutritional status, incomplete workup or records and influence of various enviornmental factors. To validate these results further prospective studies are needed

    Role of Immunological Method of Fecal Occult Blood Test for Screening Colorectal Diseases

    Get PDF
    Background: Colorectal diseases specially colorectal carcinoma is one of the major health problems throughout the world. Therefore, early diagnosis of these diseases is mandatory. There are various screening methods are used for early diagnosis of colorectal diseases. Among them fecal occult blood test is the most widely used screening test. Objectives: The objectives of the present study were to find out the role of immunological method of fecal occult blood test for screening colorectal diseases. Methods: This was a prospective study consisted of 110 patients suspected to have colorectal diseases of both sexes attending in Gastroenterology and Clinical Pathology department of Bangabandhu Sheikh Mujib Medical University. Stool samples of all the patients were examined by immunological method of fecal occult blood test and then advised for colonoscopy and histopathology for confirmatory diagnosis. The results of immunological method of fecal occult blood test and the colonoscopic findings were compared. Results. Of 110 patients, 87 (79%) cases were positive and 23 (20.9%)cases were negative by immunological method of fecal occult blood test. According to colonoscopy and histopathology, 65(32.5%) cases were found to have colorectal diseases and 45(22.5%) cases had no pathology. Diseases detected by colonoscopy in occult blood test positive patients, 18(16.4%) colorectal polyp, 24(21.8%) colonic ulcer, 8(7.3%) colorectal cancer, 5(3.5%) inflammatory bowel disease, 7(6.4%) haemorrhoids and fissure, 2(1.8%) colonic diverticulum and 1(0.9%) proctitis. Among the 65(32.5%) lesions detected by colonoscopy,62(95.3%) cases were positive by immunological method of fecal occult blood test where as only three(3) lesions were found in occult blood test negative cases. The sensitivity, specificity, PPV and NPV of immunological method of fecal occult blood test (IFOBT) for detection of occult bleeding were 95.4%, 44.4%, 71.3% and 87.0% respectively. Conclusion: It can apparently be concluded from this study that the role of immunological method of fecal occult blood test for colorectal diseases is promising in Bangladesh. Key words: Colorectal diseases; Fecal occult blood test; Immunological method DOI: http://dx.doi.org/10.3329/bsmmuj.v4i2.8634 BSMMU J 2011; 4(2):76-8

    Application of Haldane's statistical correlation theory in classical systems

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    This letter investigates the application of Haldane's statistical correlation theory in classical systems. A modified statistical correlation theory has been proposed by including non-linearity in the form of an exponent into the original theory of Haldane. The dependence of the statistical correlation on indistinguishability is highlighted. Using this modified theory, a quasi-classical derivation of intermediate statistics is shown where indistinguishability can be introduced into distinguishable systems in the form of a statistical correlation. The final result is equivalent to the classical fractional exclusion statistics (CFES), which was derived earlier using a purely classical route. An extended non-linear correlation model based on power series expansion is also proposed, which can produce various intermediate statistical models
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