6,045 research outputs found
Starfruit classification based on linear hue computation
In this paper, a classification process to group starfruit into six maturity indices is proposed based on 1- dimensional color feature called hue, which is extracted from the starfruit image. As the original hue is quantified from the nonlinear transformation of the 3-dimensional Red, Green and Blue color, this paper proposes a linear hue transformation computation based on the 2 colors of Red and Green. The proposed hue computation leads to a reduced computational burden, less computational complexity and better class discriminant capability. The hue is then applied as the input for the maturity classification process. The classification process is based on the hypothesis that for each of the maturity index, certain area of the starfruit surface is supposed to have distinctive value of the hue. In this work, the said starfruit surface area is set as 70% of the total area and based on 600 samples, the proposed technique results in 93% classification accuracy
Low-cost multimode waveguide couplers for multimode fiber-based local area networks
Novel, ultra-compact multimode fiber-matched integrated optical 1×2, 1×3 and 2×2 couplers with low excess losses and large tolerances have been designed and simulated using a fully three-dimensional beam propagation metho
Fabrication of Polymeric Multimode Waveguides and Devices in SU-8 Photoresist Using Selective Polymerization.
Large cross section multimode waveguides have been realized in SU-8 using selective polymerization. SU-8 is a negative photoresist, which has shown good optical properties and it is mechanically and chemically stable. The fabricated waveguides have very smooth sidewalls and exhibit low optical losses. The fabrication method is simple and potentially very cost effective. N x N and 1 x N multimode power splitters have been realized using this fabrication technology
Fabrication of Polymeric Multimode Waveguides for Application in the Local Area Network and Optical Interconnects.
We report the fabrication of multimode polymeric waveguides using spin coating, photolithography, and reactive ion etching. Different layer structures have been used, e.g., a UV curable resin is used as a core layer and PMMA as a lower and upper cladding. The layer systems can be spun with good uniformity with thicknesses matching multimode fiber dimensions, and smooth waveguide side-walls have been obtained after etching. The measured performance of these waveguides demonstrates that low-loss waveguides can be fabricated cheaply. The waveguides are used in the realization of novel compact multimode power splitters and star couplers
Design and fabrication of 1xN and NxN planar waveguide couplers for multimode fiber-based local area networks.
We report on the design and fabrication of compact and potentially low-cost multimode fiber matched 1 x N and N x N couplers for LAN’s. The design utilizes the self-imaging effect and tapering of the Multi-Mode Interference (MMI) section. An extended mode propagation analysis and 3-D beam propagation method (BPM) were used to analyze and design these structures. The simulations show that the couplers exhibit low excess losses, low power imbalance, and relaxed fabrication tolerances at very short device length. The devices were fabricated in polymer waveguide technology using spin coating, photolithography, and reactive ion etching. Preliminary experimental results show promising characteristics
Treatment patterns and clinical outcomes in elderly patients with HER2-positive metastatic breast cancer from the registHER observational study.
Limited data exist regarding treatment patterns and outcomes in elderly patients with HER2-positive metastatic breast cancer (MBC). registHER is an observational study of patients (N = 1,001) with HER2-positive MBC diagnosed within 6 months of enrollment and followed until death, disenrollment, or June 2009 (median follow-up 27 months). Outcomes were analyzed by age at MBC diagnosis: younger (<65 years), older (65-74 years), elderly (≥75 years). For progression-free survival (PFS) and overall survival (OS) analyses of first-line trastuzumab versus nontrastuzumab, older and elderly patients were combined. Cox regression analyses were adjusted for baseline characteristics and treatments. Estrogen receptor/progesterone receptor status was similar across age groups. Underlying cardiovascular disease was most common in elderly patients. In patients receiving trastuzumab-based first-line treatment, elderly patients were less likely to receive chemotherapy. In trastuzumab-treated patients, incidence of left ventricular dysfunction (LVD) and congestive heart failure (CHF) (grades ≥ 3) were highest in elderly patients (LVD: elderly 4.8 %, younger 2.8 %, older 1.5 %; CHF: elderly 3.2 %, younger 1.9 %, older 1.5 %). Unadjusted median PFS (months) was significantly higher in patients treated with first-line trastuzumab than those who were not (<65 years: 11.0 vs. 3.4, respectively; ≥65 years: 11.7 vs. 4.8, respectively). In patients <65 years, unadjusted median OS (months) was significantly higher in trastuzumab-treated patients; in patients ≥65 years, median OS was similar (<65 years: 40.4 vs. 25.9; ≥65 years: 31.2 vs. 28.5). In multivariate analyses, first-line trastuzumab use was associated with significant improvement in PFS across age. For OS, significant improvement was observed for patients <65 years and nonsignificant improvement for patients ≥65 years. Elderly patients with HER2-positive MBC had higher rates of underlying cardiovascular disease than their younger counterparts and received less aggressive treatment, including less first-line trastuzumab. These real-world data suggest improved PFS across all age groups and similar trends for OS
Racial disparities in treatment patterns and clinical outcomes in patients with HER2-positive metastatic breast cancer.
Data characterizing demographics, treatment patterns, and clinical outcomes in black patients with human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (MBC) are limited. registHER is a large, observational cohort study of patients (n = 1,001) with HER2-positive MBC diagnosed ≤6 months of enrollment and followed until death, disenrollment, or June 2009 (median follow-up of 27 months). Demographics, treatment patterns, and clinical outcomes were described for black (n = 126) and white patients (n = 793). Progression-free survival (PFS) following first-line therapy and overall survival (OS) were examined. Multivariate analyses adjusted for baseline and treatment factors. Black patients were more likely than white patients to be obese (body mass index ≥30), to have diabetes, and to have a history of cardiovascular disease; they were also less likely to have estrogen receptor or progesterone receptor positive disease. In patients treated with trastuzumab, the incidence of cardiac safety events (grade ≥3) was higher in black patients (10.9 %) than in white patients (7.9 %). Unadjusted median OS and PFS (months) were significantly lower in black patients than in white patients (OS: black: 27.1, 95 % confidence interval [CI] 21.3-32.1; white: 37.3, 95 % CI 34.6-41.1; PFS: black: 7.0, 95 % CI 5.7-8.2; white: 10.2, 95 % CI 9.3-11.2). The adjusted OS hazard ratio (HR) for black patients compared with white patients was 1.29 (95 % CI 1.00-1.65); adjusted PFS HR was 1.29 (95 % CI 1.05-1.59). This real-world evaluation of a large cohort of patients with HER2-positive MBC shows poorer prognostic factors and independently worse clinical outcomes in black versus white patients. Further research is needed to identify potential biologic differences that could have predictive impact for black patients or that could explain these differences
Ergo-effects of designed school furniture and sitting positions on students behaviour and Musculo-Skeletal Disorder in Nigerian tertiary institutions
Improper design of school furniture is one of the contributing factors to back pain among students as indicated in some studies. In the case of designing school furniture where sitting constitutes a considerable time in the school, seat becomes important for comfort. This study is carried out in three selected institutions in Nigeria to determine level of musculoskeletal disorder in students’ and the furniture that they use. 720 questionnaires with 240 students (120 boys and 120 girls) drawn from each participating institutions were administered and 675 responses were received. The results show that the number of students having MSD, accounted for 93.75%. However, the distributions of pain in the body parts in each school were different. The musculoskeletal pain, mostly concentrated on neck, right shoulders right elbow right wrist right hand, upper back and lower back. The result also reveals that most of the students are sitting on chairs with seat that are too high and too deep or too shallow and of tables that are too high. However, it is recommended that further study on effect of designed school furniture and sitting position in larger sample of students’ representative in Nigeria tertiary institutions should be carried out in order to reduce the effect of body pains
User friendly system for the visually impaired in learning Al-Quran
This study presents a method to enable the visually impaired Muslim to learn and read the Al-Quran using Braille Display with software help. The system reads the database which contains all verses of Al-Quran and user will need to select the verse and ayah to read. Besides that, this system can be used in a class to teach visually impaired students to learn Al-Quran. Every word or character typed by the instructor in the main Braille Panel will be transmitted to the sub Braille Panel that is connected to the main Braille Panel. The selected verse of Al-Quran and ayah will also generate an index before being transmitted to the Braille Panel. The index will be transmitted to the Braille Display for people to touch and read the display. A user friendly Graphical User Interface (GUI) will be used to fulfill the ergonomics for the visually impaired user's physical capabilities. Several approaches are used to design and implement the interface for the visually impaired like speech or sound output and Braille display. The Braille codes can be displayed using the Braille panel. The design interface and structure of the system for the visually impaired users in learning Al-Quran is presented
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