Social choice theory, game theory, and positive political theory

We consider the relationships between the collective preference and non-cooperative game theory approaches to positive political theory. In particular, we show that an apparently decisive difference between the two approachesthat in sufficiently complex environments (e.g. high-dimensional choice spaces) direct preference aggregation models are incapable of generating any prediction at all, whereas non-cooperative game-theoretic models almost always generate predictionis indeed only an apparent difference. More generally, we argue that when modeling collective decisions there is a fundamental tension between insuring existence of well-defined predictions, a criterion of minimal democracy, and general applicability to complex environments; while any two of the three are compatible under either approach, neither collective preference nor non-cooperative game theory can support models that simultaneously satisfy all three desiderata

Wear observations applied to Lifeboat Slipway Launches

It is necessary to use an inclined slipway to launch a large lifeboat in locations where there is no natural harbour or where there is a large tidal range. Slipway stations consist of an initial section where the boat is held on rollers followed by an inclined keelway of nickel/chromium coated steel, the lifeboat is released from the top of the slipway and proceeds under its own weight into the water. The lifeboat is subsequently recovered to the top of the slipway using a winch line. With the introduction of the new, larger Tamar class lifeboat existing boathouses are being upgraded and existing low friction coated steel slipway lining materials replaced with a low-friction jute fibre/phenolic resin composite, which is designed to operate with unlubricated conditions. This has led to problems of high wear on slipway panels, particularly where the lifeboat mounts the slipway for recovery. This paper describes a method for assessing slipway lining materials and lubricants. The selection of an appropriate test machine, the TE92 rotary tribometer, and design of a modified ring on disc arrangement incorporating panel interfaces and attaching holes effects is described. An experimental methodology is developed using programmed running intervals to simulate dwell effects. Experimental data is thus presented to establish slipway panel wear rates for a range of lubricants and contact pressures. Experimental results are incorporated into real-world slipway surveys to develop the wear scenario. Results and implications of this research for future lifeboat slipway design are discussed

A plausible method for fatigue life prediction of boats in a data scarce environment

Within the marine world many boats are constructed from composite materials, that useclassification society rules to predict their strength. As these vessels age, fatigue and remaining lifetime are of considerable interest to owners and operators. This paper seeks to identify an appropriate S-N curve and produce an example lifetime calculation

Amyloid-β acts as a regulator of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2.

BACKGROUND: It is becoming increasingly evident that deficits in the cortex and hippocampus at early stages of dementia in Alzheimer's disease (AD) are associated with synaptic damage caused by oligomers of the toxic amyloid-β peptide (Aβ42). However, the underlying molecular and cellular mechanisms behind these deficits are not fully understood. Here we provide evidence of a mechanism by which Aβ42 affects synaptic transmission regulating neurotransmitter release. METHODOLOGY/FINDINGS: We first showed that application of 50 nM Aβ42 in cultured neurones is followed by its internalisation and translocation to synaptic contacts. Interestingly, our results demonstrate that with time, Aβ42 can be detected at the presynaptic terminals where it interacts with Synaptophysin. Furthermore, data from dissociated hippocampal neurons as well as biochemical data provide evidence that Aβ42 disrupts the complex formed between Synaptophysin and VAMP2 increasing the amount of primed vesicles and exocytosis. Finally, electrophysiology recordings in brain slices confirmed that Aβ42 affects baseline transmission. CONCLUSIONS/SIGNIFICANCE: Our observations provide a necessary and timely insight into cellular mechanisms that underlie the initial pathological events that lead to synaptic dysfunction in Alzheimer's disease. Our results demonstrate a new mechanism by which Aβ42 affects synaptic activity

The visual standards for the selection and retention of astronauts

Literature search with abstracts on visual performance standards for selection and retention of astronaut

Experimental Wear Modelling of Lifeboat Slipway Launches

It is necessary to use an inclined slipway to launch lifeboats in locations where there is no natural harbour. Slipway stations consist of an initial roller section followed by an inclined keelway, the lifeboat is released from the top of the slipway and proceeds under its own weight into the water. Contact is between the lifeboat keel and a lined, greased keelway and this that determines the friction along the slipway. This paper describes a bench test methodology to investigate this contact. The selection of a modified TE57 reciprocating tribometer and design of a modified pin on plate arrangement is discussed. A test schedule for both the original nickel/chromium coated steel lining and the new low-friction jute fibre/phenolic resin composite lining is developed to accurately reflect real world conditions including environmental contamination such as seawater or wind-blown sand. Environmentally conscious lubricants including water and bio-greases are investigated and compared for their effects in reducing slipway panel friction and wear. Experimental data is collected to establish wear mechanisms, wear volumes and friction characteristics for a range of lubricants and environmental contaminants for the two most common lifeboat keelway lining materials. Implications of this research for future lifeboat slipway design are discussed

Development of LCA calculator to support community infrastructure co-design

Purpose LCA tools are increasingly used to support decision making. However, the current generation of tools is mainly targeted at users with significant background in industrial and environmental processes. This paper presents a novel process of developing the LCA Calculator with inputs from community members embedded in a co-design process. It demonstrates how engineering tools can be developed by considering end-user perspectives and used to communicate systems thinking in infrastructure co-design. Methods The process of the LCA Calculator development was informed by the outcomes of community engagement through the co-design process. The method consists of four parts including horizon scanning of suitable technology options, LCA modelling, development of the LCA Calculator and pilot testing of the Calculator with residents from the selected case study community. The case study community are residents of a social housing estate in central London. The estate has a total of 123 flats arranged in three low-rise blocks with shared gardens and courtyards. Three technology options—wormery composting, rainwater harvesting and urban food growing—were used to illustrate the LCA methods and test the Calculator development. Results and discussion The Calculator developed in this project pushes the boundaries beyond expert users to develop a new generation of LCA tools for a wider range of decision makers. The LCA results were communicated using the LCA Calculator in a workshop as part of the co-design process. The communication process was supported by the visual language of the Calculator, information sheets of the technology options and community members’ involvement in the process of the Calculator development. The Calculator provided a solid base on which sustainable design discussions could happen. It provided to the participants valuable insights into the scale of material flow given different design choices—such as the amount of waste generated over a month or the irrigation requirements of a raised bed—and environmental impacts of these options. Conclusions A prototype version of an LCA Calculator software tool has been developed to enable rapid assessment of conceptual design of engineering systems. The LCA Calculator was successfully tested at a community workshop, enabling clear engagement between engineering design choices and resource and environmental impacts. The Calculator facilitated a two-way exchange between community members and infrastructure designers that embeds end-user perspectives in the design and implementation of the infrastructure they use, taking into account lifecycle impacts of technology and material options

Elections, Coalitions, and Legislative Outcomes

This paper develops a multi-stage game-theoretic model of three-party competition under proportional representation. The final policy outcome of the game is generated by a non-cooperative bargaining game between the parties in the elected legislature. This game is essentially defined by the vote shares each party receives in the general election, and the parties' electoral policy positions. At the electoral stage parties and voters are strategic in that they take account of the legislative implications of any electoral outcome. We solve for equilibrium electoral positions by the parties and final policy outcomes

Wear and Friction Modeling on Lifeboat Launch Systems

The RNLI provides search and rescue cover along the UK and RoI coast using a variety of lifeboats and launch techniques. In locations where there is no natural harbour it is necessary to use a slipway to launch the lifeboat into the sea. Lifeboat slipway stations consist of an initial section where the boat is held on rollers followed by an inclined keelway lined with low friction composite materials, the lifeboat is released from the top of the slipway and proceeds under its own weight into the water. The lifeboat is later recovered using a winch line. It is common to manually apply grease to the composite slipway lining before each launch and recovery in order to ensure sufficiently low friction for successful operation. With the introduction of the Tamar class lifeboat it is necessary to upgrade existing boathouses and standardise slipway operational procedures to ensure consistent operation. The higher contact pressures associated with the new lifeboat have led to issues of high friction and wear on the composite slipway linings and the manual application of grease to reduce friction is to be restricted due to environmental impact and cost factors. This paper presents a multidisciplinary approach to modelling slipway panel wear and friction using tribometer testing in conjunction with finite element analysis and slipway condition surveys to incorporate common real-world effects such as panel misalignments. Finally, it is shown that a freshwater lubrication system is effective, reducing cost and environmental impacts while maintaining good friction and wear performance