816 research outputs found

    Molecular Dynamics Simulation of the ENTH Domain on Lipid Bilayer

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    This research study compares the effect of polypropylene and wool fibers on the mechanical properties of natural polymer based stabilized soils. Biocomposites are becoming increasingly prevalent and this growth is expected to continue within a number of sectors including building materials. The aim of this study was to investigate the influence of different fiber reinforced natural polymer stabilized soils with regards to mechanical properties and fiber adhesion characteristics. The polymer includes alginate, which is used in a wide range of applications but has not been commonly used within engineering and construction applications. In recent years, natural fibers have started to be used as an ecological friendly alternative for soil reinforcement within a variety of construction applications. Test results in this study have compared the effects of adding natural and synthetic fibers to clay soils and discussed the importance of an optimum soil specification. A correlation between the micro structural analysis using scanning electron microscope (SEM), fiber typology, fiber–matrix bonds and the mechanical properties of the stabilized soils is also discussed

    Stationary and Transient Work-Fluctuation Theorems for a Dragged Brownian Particle

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    Recently Wang et al. carried out a laboratory experiment, where a Brownian particle was dragged through a fluid by a harmonic force with constant velocity of its center. This experiment confirmed a theoretically predicted work related integrated (I) Transient Fluctuation Theorem (ITFT), which gives an expression for the ratio for the probability to find positive or negative values for the fluctuations of the total work done on the system in a given time in a transient state. The corresponding integrated stationary state fluctuation theorem (ISSFT) was not observed. Using an overdamped Langevin equation and an arbitrary motion for the center of the harmonic force, all quantities of interest for these theorems and the corresponding non-integrated ones (TFT and SSFT, resp.) are theoretically explicitly obtained in this paper. While the (I)TFT is satisfied for all times, the (I)SSFT only holds asymptotically in time. Suggestions for further experiments with arbitrary velocity of the harmonic force and in which also the ISSFT could be observed, are given. In addition, a non-trivial long-time relation between the ITFT and the ISSFT was discovered, which could be observed experimentally, especially in the case of a resonant circular motion of the center of the harmonic force.Comment: 20 pages, 3 figure

    Hot Streaks in Artistic, Cultural, and Scientific Careers

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    The hot streak, loosely defined as winning begets more winnings, highlights a specific period during which an individual's performance is substantially higher than her typical performance. While widely debated in sports, gambling, and financial markets over the past several decades, little is known if hot streaks apply to individual careers. Here, building on rich literature on lifecycle of creativity, we collected large-scale career histories of individual artists, movie directors and scientists, tracing the artworks, movies, and scientific publications they produced. We find that, across all three domains, hit works within a career show a high degree of temporal regularity, each career being characterized by bursts of high-impact works occurring in sequence. We demonstrate that these observations can be explained by a simple hot-streak model we developed, allowing us to probe quantitatively the hot streak phenomenon governing individual careers, which we find to be remarkably universal across diverse domains we analyzed: The hot streaks are ubiquitous yet unique across different careers. While the vast majority of individuals have at least one hot streak, hot streaks are most likely to occur only once. The hot streak emerges randomly within an individual's sequence of works, is temporally localized, and is unassociated with any detectable change in productivity. We show that, since works produced during hot streaks garner significantly more impact, the uncovered hot streaks fundamentally drives the collective impact of an individual, ignoring which leads us to systematically over- or under-estimate the future impact of a career. These results not only deepen our quantitative understanding of patterns governing individual ingenuity and success, they may also have implications for decisions and policies involving predicting and nurturing individuals with lasting impact

    Orientational Ordering in Spatially Disordered Dipolar Systems

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    This letter addresses basic questions concerning ferroelectric order in positionally disordered dipolar materials. Three models distinguished by dipole vectors which have one, two or three components are studied by computer simulation. Randomly frozen and dynamically disordered media are considered. It is shown that ferroelectric order is possible in spatially random systems, but that its existence is very sensitive to the dipole vector dimensionality and the motion of the medium. A physical analysis of our results provides significant insight into the nature of ferroelectric transitions.Comment: 4 pages twocolumn LATEX style. 4 POSTSCRIPT figures available from [email protected]

    A multibaker map for shear flow and viscous heating

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    A consistent description of shear flow and the accompanied viscous heating as well the associated entropy balance is given in the framework of a deterministic dynamical system. A laminar shear flow is modeled by a Hamiltonian multibaker map which drives velocity and temperature fields. In an appropriate macroscopic limit one recovers the Navier-Stokes and heat conduction equations along with the associated entropy balance. This indicates that results of nonequilibrium thermodynamics can be described by means of an abstract, sufficiently chaotic and mixing dynamics. A thermostating algorithm can also be incorporated into this framework.Comment: 11 pages; RevTex with multicol+graphicx packages; eps-figure

    Curvature-coupling dependence of membrane protein diffusion coefficients

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    We consider the lateral diffusion of a protein interacting with the curvature of the membrane. The interaction energy is minimized if the particle is at a membrane position with a certain curvature that agrees with the spontaneous curvature of the particle. We employ stochastic simulations that take into account both the thermal fluctuations of the membrane and the diffusive behavior of the particle. In this study we neglect the influence of the particle on the membrane dynamics, thus the membrane dynamics agrees with that of a freely fluctuating membrane. Overall, we find that this curvature-coupling substantially enhances the diffusion coefficient. We compare the ratio of the projected or measured diffusion coefficient and the free intramembrane diffusion coefficient, which is a parameter of the simulations, with analytical results that rely on several approximations. We find that the simulations always lead to a somewhat smaller diffusion coefficient than our analytical approach. A detailed study of the correlations of the forces acting on the particle indicates that the diffusing inclusion tries to follow favorable positions on the membrane, such that forces along the trajectory are on average smaller than they would be for random particle positions.Comment: 16 pages, 8 figure

    Out-of-core solution of eigenproblems for macromolecular simulations

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    We consider the solution of large-scale eigenvalue problems that appear in the motion simulation of complex macromolecules on desktop platforms. To tackle the dimension of the matrices that are involved in these problems, we formulate out-of-core (OOC) variants of the two selected eigensolvers, that basically decouple the performance of the solver from the storage capacity. Furthermore, we contend with the high computational complexity of the solvers by off-loading the arithmetically-intensive parts of the algorithms to a hardware graphics accelerator
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