Efficacy of pegylated interferon plus ribavirin in combination with corticosteroid for two cases of combined hepatitis C and autoimmune hepatitis

The treatment strategy for cases of combined autoimmune hepatitis (AIH) and chronic hepatitis C (CHC) has not yet been established. A 47-year-old woman and a 53-year-old-woman were hospitalized for treatment of CHC. Ultrasonography and histological findings revealed that their liver was not cirrhotic but did have chronic damage. The histological findings of both patients were suggestive of AIH. The patients were systematically treated with pegylated interferon-alpha 2b plus ribavirin which was preceded by and combined with corticosteroid (CS), and showed sustained virological responses and normal liver function. Although these two patients with combined AIH and CHC were successfully treated with this regimen, careful attention to exacerbation of hepatic inflammation is needed because hepatitis C viral load was increased due to immunosuppression during CS treatment

Production Of Bioethanol From Different Leaves Waste And Performance And Emission Characteristics Of Single Cylinder CI Engine

Abstract Background: The need of bioethanol is being increased nowadays; hence the production of bioethanol must be increased using cheaper and eco-friendly raw materials. Based on these criteria, different leaves wastes are considered as cheaper and eco-friendly. In the present study selected tree leaves wastes such as Rain tree, Jackfruit tree, Mango tree and Singapore cherry tree leaves waste were used as raw materials to produce bioethanol by using Saccharomyces cerevisiae (yeast). The operating conditions are pH 6.5, temperature 27±2°C, speed 80rpm, fermentation period 10 days. Also an attempt has been made to find out the suitability of extracted bioethanol as a fuel in CI engine. Results: Experimental work on performance and emission characteristics of ethanol blended diesel fuel was conducted on single cylinder four stroke CI engines at operating pressure 210 bar. The results obtained from this work shows that the higher rate of ethanol can be produced through fermentation of wet Jackfruit tree leaves, which gives good percentage of ethanol as compared to other tree leaves wastes. Conclusions: The conversion of waste into fuel, which forms an attractive solution towards both waste management and Biofuels generation.This study concludes that the Jackfruit tree leaves contain rich fermentable sugar can be converted into useful products like bioethanol that can serve as an alternative energy source.</jats:p