Fractional graph Laplacian for image reconstruction

Image reconstruction problems, like image deblurring and computer tomography, are usually ill-posed and require regularization. A popular approach to regularization is to substitute the original problem with an optimization problem that minimizes the sum of two terms, an term and an term with . The first penalizes the distance between the measured data and the reconstructed one, the latter imposes sparsity on some features of the computed solution. In this work, we propose to use the fractional Laplacian of a properly constructed graph in the term to compute extremely accurate reconstructions of the desired images. A simple model with a fully automatic method, i.e., that does not require the tuning of any parameter, is used to construct the graph and enhanced diffusion on the graph is achieved with the use of a fractional exponent in the Laplacian operator. Since the fractional Laplacian is a global operator, i.e., its matrix representation is completely full, it cannot be formed and stored. We propose to replace it with an approximation in an appropriate Krylov subspace. We show that the algorithm is a regularization method under some reasonable assumptions. Some selected numerical examples in image deblurring and computer tomography show the performance of our proposal

Cluster randomized trial assessing the effects of rapid ethical assessment on informed consent comprehension in a low-resource setting

Background Maximizing comprehension is a major challenge for informed consent processes in low-literacy and resource-limited settings. Application of rapid qualitative assessments to improve the informed consent process is increasingly considered useful. This study assessed the effects of Rapid Ethical Assessment (REA) on comprehension, retention and quality of the informed consent process. Methods A cluster randomized trial was conducted among participants of HPV sero-prevalence study in two districts of Northern Ethiopia, in 2013. A total of 300 study participants, 150 in the intervention and 150 in the control group, were included in the study. For the intervention group, the informed consent process was designed with further revisions based on REA findings. Informed consent comprehension levels and quality of the consent process were measured using the Modular Informed Consent Comprehension Assessment (MICCA) and Quality of Informed Consent (QuIC) process assessment tools, respectively. Result Study recruitment rates were 88.7 % and 80.7 % (p = 0.05), while study retention rates were 85.7 % and 70.3 % (p < 0.005) for the intervention and control groups respectively. Overall, the mean informed consent comprehension scores for the intervention and control groups were 73.1 % and 45.2 %, respectively, with a mean difference in comprehension score of 27.9 % (95 % CI 24.0 % - 33.4 %; p < 0.001,). Mean scores for quality of informed consent for the intervention and control groups were 89.1 % and 78.5 %, respectively, with a mean difference of 10.5 % (95 % CI 6.8 -14.2 %; p < 0.001). Conclusion Levels of informed consent comprehension, quality of the consent process, study recruitment and retention rates were significantly improved in the intervention group. We recommend REA as a potential modality to improve informed consent comprehension and quality of informed consent process in low resource settings

Costos de la licencia de maternidad para apoyar la lactancia materna en Brasil, Ghana y México

Objective To develop a method to assess the cost of extending the duration of maternity leave for formally-employed women at the national level and apply it in Brazil, Ghana and Mexico. Methods We adapted a World Bank costing method into a five-step method to estimate the costs of extending the length of maternity leave mandates. Our method used the unit cost of maternity leave based on working women’s weekly wages; the number of additional weeks of maternity leave to be analysed for a given year; and the weighted population of women of reproductive and legal working age in a given country in that year. We weighted the population by the probability of having a baby that year among women in formal employment, according to individual characteristics. We applied nationally representative cross-sectional data from fertility, employment and population surveys to estimate the costs of maternity leave for mothers employed in the formal sector in Brazil, Ghana and Mexico for periods from 12 weeks up to 26 weeks, the WHO target for exclusive breastfeeding. Findings We estimated that 640 742 women in Brazil, 33 869 in Ghana and 288 655 in Mexico would require formal maternity leave annually. The median weekly cost of extending maternity leave for formally working women was purchasing power parity international dollars (PPP$) 195.07 per woman in Brazil, PPP$ 109.68 in Ghana and PPP$ 168.83 in Mexico. Conclusion Our costing method could facilitate evidence-based policy decisions across countries to improve maternity protection benefits and support breastfeeding

Costing a Maternity Leave Cash Transfer to Support Breastfeeding Among Informally Employed Mexican Women

Background: Investing in maternity protection for working women is an important social equity mechanism. Addressing the maternity leave needs of women employed in the informal sector economy should be a priority as more than half of women in Latin America, South Asia, and sub-Saharan Africa are employed in this sector. Objective: To develop a costing methodology framework to assess the financial feasibility, at the national level, of implementing a maternity cash transfer for informally employed women. Methods: A World Bank costing methodology was adapted for estimating the financial need to establish a maternity cash transfer benefit. The methodology estimates the cash transfer’s unitary cost, the incremental coverage of the policy in terms of time, the weighted population to be covered, and the administrative costs. The 6-step methodology uses employment and sociodemographic data that are available in many countries through employment and demographic surveys and the population census. The methodology was tested with data for Mexico assuming different cash transfer unitary costs and the benefit’s time coverage. Results: The methodological framework estimated that the annual financial needs of setting up a maternity cash transfer for informally working women in Mexico ranges between US$87 million and US$280 million. Conclusions: A pragmatic methodology for assessing the costs of maternity cash transfer for informally employed women was developed. In the case of Mexico, the maternity cash transfer for women in the informal sector is financially feasible

Hypoglycemic effect of dietary Acrocomia aculeata kernel oil on type 2 diabetic rats.

Macauba (Acrocomia ssp), is a palm tree native to tropical America found mostly in the wetlands (Pantanal) and Savannah like area (Cerrados) of Brazil. Its fruit yields pulp and kernel oils, whose fatty acid compositions are very distinguishable. The pulp oil is rich in oleic acid, the macauba provides also kernel oil rich in medium chain fatty acids (MCFAs) accounts for approximately 50% of the total composition, and lauric acid is the most abundant. In our research group, we have been looking at alternative sources other than carbohydrates to supply energy as a strategy to mitigate the deleterious effects of type 2 diabetes. Th

Factors associated with pacifier use among children of working women with childcare in the workplace

ABSTRACTPurpose: to identify the prevalence of pacifier use as well as the reasons for introducing a pacifier and to analyze factors associated with this practice among children of working women with childcare in the workplace.Methods: a cross-sectional study was conducted with 46 women working at a higher education institution that offered childcare in the workplace; the children were in the age range 2.6 years. Data collection was carried out using a self-report questionnaire filled at home. Reasons for introducing a pacifier were analyzed descriptively; Poisson regression was used in the multiple analysis.Results: the prevalence of pacifier use was 63%. Most women offered the pacifier after the infant's 16th day of life, in order to calm the baby. In the multiple analysis, higher maternal education was associated with pacifier use.Conclusion: a high prevalence of pacifier use was observed, as well as early pacifier introduction, among children of working women with childcare in the workplace. With regard to the factors associated with pacifier use in this population, lower maternal education acted as a protective factor against pacifier use.RESUMOObjetivo: identificar a prevalência de uso da chupeta e os motivos para sua introdução além de analisar os fatores associados a essa prática entre filhos de mulheres com creche no local de trabalho.Métodos: estudo transversal realizado com 46 mulheres trabalhadoras de uma Instituição de Ensino Superior com creche no local de trabalho, mães de crianças com idade média de 2,6 anos. Para coleta de dados, utilizou-se questionário enviado para casa. Procedeu-se análise descritiva dos motivos da introdução da chupeta e para a análise múltipla utilizou-se regressão de Poisson.Resultados: a prevalência do uso de chupeta foi de 63%. A maioria ofereceu a chupeta após o 16º dia, com o intuito de acalmá-la. Na análise múltipla, a maior escolaridade materna associou-se ao uso de chupeta.Conclusão: constatou-se a alta prevalência de uso e introdução precoce de chupeta entre filhos de mulheres trabalhadoras com creche no local de trabalho. Com relação aos fatores associados ao uso de chupeta nesta população verificou-se a menor escolaridade das mães como fator de proteção ao uso de chupeta