Organizational Activities in Nursing Research Transfer from Viewpoint of Nurse Educators in Iranian Universities of Medical Sciences

Background: Transferring research-based knowledge into practice would help to maximize the quality of health care. However, the role of knowledge producers and the organizational roles related to knowledge transfer have been largely ignored. Objectives: This study was accomplished with the aim of describing the organizational activities needed to transfer the findings of nursing research from the viewpoint of nurse educators in Iranian Universities of Medical Sciences. Patients and Methods: This descriptive study was carried out with participating 279 nurse educators of medical sciences universities. Data were collected using Knowledge Translation Self-Assessment Tool for Research Institutes (SATORI). Results: Nursing faculty members evaluated the organizational activities of transferring the knowledge of nursing research at the “medium” level and for the domains of “the question of research” and “promoting the use of evidence” at a “weak” level and in the domains of “knowledge production” and “knowledge transfer” at a “medium” level. Conclusions: Organizational activities related to the knowledge transfer of nursing research are demonstrably low (medium at best). It is recommended that in each faculty and with the participation of all faculty members, the research transferring procedure should be assessed and all necessary changes needed to improve the research transferring procedure should be implemented

A Multi-agent Reinforcement Learning Study of Emergence of Social Classes out of Arbitrary Governance: The Role of Environment

There are several theories in economics regarding the roots or causes of prosperity in a society. One of these theories or hypotheses -- named geography hypothesis -- mentions that the reason why some countries are prosperous and some others are poor is the geographical location of the countries in the world as makes their climate and environment favorable or unfavorable regarding natural resources. Another competing hypothesis states that man-made institutions particularly inclusive political institutions are the reasons why some countries are prosperous and some others are poor. On the other hand, there is a specific political theory developed for the long-term social development in Iran -- named Arbitrary Rule and Aridisolatic Society which particularly emphasizes on the role of aridity to shape arbitrary political and economical institutions in Iran, without any functional social classes in the society. In this paper, by extending the AI-Economist -- a recently developed two-level multi-agent reinforcement learning environment -- I show that when the central planner is ruling the environment by arbitrary rules, the society evolves through different paths in different environments. In the environment having band-like vertical isolated patches of natural resources, all mobile agents are equally exploited by the central planner and the central planner is also not gaining any income, while in the society having more uniformly distributed natural resources, the productivity and Maximin are higher and the society generates a heterogeneous stratified social structure. All these findings provide a partial answer to the above debate and reconcile the role of geography and political institutions on the long-term development in a region

The battle of the sexes starts in the oviduct: modulation of oviductal transcriptome by X and Y-bearing spermatozoa

BACKGROUND:Sex allocation of offspring in mammals is usually considered as a matter of chance, being dependent on whether an X- or a Y-chromosome-bearing spermatozoon reaches the oocyte first. Here we investigated the alternative possibility, namely that the oviducts can recognise X- and Y- spermatozoa, and may thus be able to bias the offspring sex ratio. RESULTS:By introducing X- or Y-sperm populations into the two separate oviducts of single female pigs using bilateral laparoscopic insemination we found that the spermatozoa did indeed elicit sex-specific transcriptomic responses. Microarray analysis revealed that 501 were consistently altered (P-value <0.05) in the oviduct in the presence of Y-chromosome-bearing spermatozoa compared to the presence of X-chromosome-bearing spermatozoa. From these 501 transcripts, 271 transcripts (54.1%) were down-regulated and 230 transcripts (45.9%) were up-regulated when the Y- chromosome-bearing spermatozoa was present in the oviduct. Our data showed that local immune responses specific to each sperm type were elicited within the oviduct. In addition, either type of spermatozoa elicits sex-specific signal transduction signalling by oviductal cells. CONCLUSIONS:Our data suggest that the oviduct functions as a biological sensor that screens the spermatozoon, and then responds by modifying the oviductal environment. We hypothesize that there might exist a gender biasing mechanism controlled by the female

An accelerated stochastic vortex structure method for particle collision and agglomeration in homogeneous turbulence

Modeling the response of interacting particles, droplets, or bubbles to subgrid-scale fluctuations in turbulent flows is a long-standing challenge in multiphase flow simulations using the Reynolds-Averaged Navier-Stokes approach. The problem also arises for large-eddy simulation for sufficiently small values of the Kolmogorov-scale particle Stokes number. This paper expands on a recently proposed stochastic vortex structure (SVS) method for modeling of turbulence fluctuations for colliding or otherwise interacting particles. An accelerated version of the SVS method was developed using the fast multipole expansion and local Taylor expansion approach, which reduces computation speed by two orders of magnitude compared to the original SVS method. Detailed comparisons are presented showing close agreement of the energy spectrum and probability density functions of various fields between the SVS computational model, direct numerical simulation (DNS) results, and various theoretical and experimental results found in the literature. Results of the SVS method for particle collision rate and related measures of particle interaction exhibit excellent agreement with DNS predictions for homogeneous turbulent flows. The SVS method was also used with adhesive particles to simulate formation of particle agglomerates with different values of the particle Stokes and adhesion numbers, and various measures of the agglomerate structure are compared to the DNS results

On the fracture prediction of 304L stainless steel sheets utilizing different hardening models

Fracture prediction is one of the challenging problems in sheet metals. Forming limit curves at fracture (FLCF), as a tool to determine fracture in sheet metal processes, are obtained through the use of numerical analyses. As one of the approaches, the ductile fracture criteria (DFCs) represent the fracture initiation of the sheets formed by different loading histories. In this study, the effects of three different hardening models on different DFCs to predict the fracture for stainless steel 304L have been investigated. The results show that most of DFCs work better in the region. epsilon(2) 0 where the stretching conditions are dominant, none of them could precisely estimate the fracture initiation

A stochastic vortex structure method for interacting particles in turbulent shear flows

In a recent study, we have proposed a new synthetic turbulence method based on stochastic vortex structures (SVSs), and we have demonstrated that this method can accurately predict particle transport, collision, and agglomeration in homogeneous, isotropic turbulence in comparison to direct numerical simulation results. The current paper extends the SVS method to non-homogeneous, anisotropic turbulence. The key element of this extension is a new inversion procedure, by which the vortex initial orientation can be set so as to generate a prescribed Reynolds stress field. After validating this inversion procedure for simple problems, we apply the SVS method to the problem of interacting particle transport by a turbulent planar jet. Measures of the turbulent flow and of particle dispersion, clustering, and collision obtained by the new SVS simulations are shown to compare well with direct numerical simulation results. The influence of different numerical parameters, such as number of vortices and vortex lifetime, on the accuracy of the SVS predictions is also examined

The epidemiology of skin cancer and its trend in Iran

Background: One of the most common cancers is skin cancer worldwide. Since incidence and cost of treatment of the cancer are increasing, it is necessary to further investigate to prevent and control this disease. This study aimed to determine skin cancer trend and epidemiology in Iran. Methods: This study was done based on existing data. Data used in this study were obtained from a national registry of cancer cases and the Disease Management Center of Ministry of Health in Iran. All cases registered in the country were included during 2004�2008. Incidence rates were reported based on the direct method and standard population of World Health Organization. Results: Based on the results of this study, the incidence of skin cancer is rising in Iran and the sex ratio was more in men than women in all provinces. The age-standardized incidence rate (ASR) of skin cancer was highest in males in Semnan, Isfahan, and Hamedan provinces (34.9, 30.80, and 28.84, respectively). The highest ASRs were seen in females in Semnan, Yazd, and Isfahan provinces (26.7, 24.14, and 18.97, respectively). The lowest ASR in male was observed in Sistan and Baluchestan, and in female in Hormozgan provinces. Conclusions: The incidence of skin cancer is increasing in the country. Therefore, the plan for the control and prevention of this cancer must be a high priority for health policy makers. © 2015 Razi S

Effect of green cardamom on lipoproteins, glycemic control and anthropometric parameters: A meta-analysis of randomized clinical trials

Introduction: The aim of this systematic review and meta-analysis was to summarize all the existing randomized controlled trials (RCTs) evidence and to evaluate the effects of green cardamom on lipoproteins, glycemic control and anthropometric parameters in healthy and/or with disease types compared with the control. Method: Two independent authors systematically searched online databases including EMBASE, Scopus, PubMed, Cochrane Library, and Web of Science from inception until 30th July 2019. RCTs complying with the following criteria were included in this meta-analysis: human trials with either cross-over design or parallel design, trials with data on the effects of green cardamom on serum lipoproteins and glycemic control and anthropometric parameters with standard deviation and related 95 confidence interval for the both intervention and placebo groups. The heterogeneity among the included studies was assessed using Cochrane's Q test and I-square (I2) statistic. Data were pooled using a random-effects model and weighted mean difference (WMD) was considered as the overall effect size. Result: Seven trials were included in this meta-analysis. Triglycerides were significantly reduced after cardamom supplementation when compared with the control group. Cardamom intake from 3 small studies resulted in a significant increase in BMI when compared with the control group. However, cardamom supplementation did not have any significant effect on total cholesterol, LDL-cholesterol, HDL-cholesterol, fasting plasma glucose and body weight when compared with the control group. Conclusion: This meta-analysis demonstrated that green cardamom intake significantly reduced triglycerides levels which may have played an indirect role in improved clinical symptoms in diseases with metabolic disorders. © 2020 European Society for Clinical Nutrition and Metabolis

Diverging results of areal and volumetric bone mineral density in Down syndrome

Population with Down syndrome (DS) has lower areal BMD, in association with their smaller skeletal size. However, volumetric BMD and other indices of bone microarchitecture, such as trabecular bone score (TBS) and calcaneal ultrasound (QUS), were normal. INTRODUCTION: Patients with DS have a number of risk factors that could predispose them to osteoporosis. Several studies reported that people with DS also have lower areal bone mineral density, but differences in the skeletal size could bias the analysis. METHODS: Seventy-five patients with DS and 76 controls without intellectual disability were recruited. Controls were matched for age and sex. Bone mineral density (BMD) was measure by Dual-energy X-ray Absorptiometry (DXA), and volumetric bone mineral density (vBMD) was calculated by published formulas. Body composition was also measured by DXA. Microarchitecture was measured by TBS and QUS. Serum 25-hidroxyvitamin D (25OHD), parathyroid hormone (PTH), aminoterminal propeptide of type collagen (P1NP), and C-terminal telopeptide of type I collagen (CTX) were also determined. Physical activity was assessed by the International Physical Activity Questionnaires (IPAQ-short form). To evaluate nutritional intake, we recorded three consecutive days of food. RESULTS: DS individuals had lower height (151 ± 11 vs. 169 ± 9 cm). BMD was higher in the controls (lumbar spine (LS) 0.903 ± 0.124 g/cm2 in patients and 0.997 ± 0.115 g/cm2 in the controls; femoral neck (FN) 0.761 ± .126 g/cm2 and 0.838 ± 0.115 g/cm2, respectively). vBMD was similar in the DS group (LS 0.244 ± 0.124 g/cm3; FN 0.325 ± .0.073 g/cm3) and the controls (LS 0.255 ± 0.033 g/cm3; FN 0.309 ± 0.043 g/cm3). Microarchitecture measured by QUS was slightly better in DS, and TBS measures were similar in both groups. 25OHD, PTH, and CTX were similar in both groups. P1NP was higher in the DS group. Time spent on exercise was similar in both groups, but intensity was higher in the control group. Population with DS has correct nutrition. CONCLUSIONS: Areal BMD is reduced in DS, but it seems to be related to the smaller body and skeletal size. In fact, the estimated volumetric BMD is similar in patients with DS and in control individuals. Furthermore, people with DS have normal bone microarchitecture