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Dominant hemisphere functional networks compensate for structural connectivity loss to preserve phonological retrieval with aging
Introduction
Loss of hemispheric asymmetry during cognitive tasks has been previously demonstrated in the literature. In the context of language, increased right hemisphere activation is observed with aging. Whether this relates to compensation to preserve cognitive function or dedifferentiation implying loss of hemispheric specificity without functional consequence, remains unclear.
Methods
With a multifaceted approach, integrating structural and functional imaging data during a word retrieval task, in a group of younger and older adults with equivalent cognitive performance, we aimed to establish whether interactions between hemispheres or reorganization of dominant hemisphere networks preserve function. We examined functional and structural connectivity on data from our previously published functional activation study. Functional connectivity was measured using psychophysiological interactions analysis from the left inferior frontal gyrus (LIFG) and the left insula (LINS), based on published literature, and the right inferior frontal gyrus (RIFG) based on our previous study.
Results
Although RIFG showed increased activation, its connectivity decreased with age. Meanwhile, LIFG and LINS connected more bilaterally in the older adults. White matter integrity, measured by fractional anisotropy (FA) from diffusion tensor imaging, decreased significantly in the older group. Importantly, LINS functional connectivity to LIFG correlated inversely with FA.
Conclusions
We demonstrate that left hemispheric language areas show higher functional connectivity in older adults with intact behavioral performance, and thus, may have a role in preserving function. The inverse correlation of functional and structural connectivity with age is in keeping with emerging literature and merits further investigation with tractography studies and in other cognitive domains
Massive Three-Dimensional Supergravity From R+R^2 Action in Six Dimensions
We obtain a three-parameter family of massive N=1 supergravities in three
dimensions from the 3-sphere reduction of an off-shell N=(1,0) six-dimensional
Poincare supergravity that includes a curvature squared invariant. The
three-dimensional theory contains an off-shell supergravity multiplet and an
on-shell scalar matter multiplet. We then generalise this in three dimensions
to an eight-parameter family of supergravities. We also find a duality
relationship between the six-dimensional theory and the N=(1,0) six-dimensional
theory obtained through a T^4 reduction of the heterotic string effective
action that includes the higher-order terms associated with the
supersymmetrisation of the anomaly-cancelling \tr(R\wedge R) term.Comment: Latex, 32 Pages, an equation is corrected, a few new equations and a
number of clarifying remarks are adde
Sentiment Recognition in Egocentric Photostreams
Lifelogging is a process of collecting rich source of information about daily
life of people. In this paper, we introduce the problem of sentiment analysis
in egocentric events focusing on the moments that compose the images recalling
positive, neutral or negative feelings to the observer. We propose a method for
the classification of the sentiments in egocentric pictures based on global and
semantic image features extracted by Convolutional Neural Networks. We carried
out experiments on an egocentric dataset, which we organized in 3 classes on
the basis of the sentiment that is recalled to the user (positive, negative or
neutral)
Critical and Non-Critical Einstein-Weyl Supergravity
We construct N=1 supersymmetrisations of some recently-proposed theories of
critical gravity, conformal gravity, and extensions of critical gravity in four
dimensions. The total action consists of the sum of three separately off-shell
supersymmetric actions containing Einstein gravity, a cosmological term and the
square of the Weyl tensor. For generic choices of the coefficients for these
terms, the excitations of the resulting theory around an AdS_4 background
describe massive spin-2 and massless spin-2 modes coming from the metric;
massive spin-1 modes coming from a vector field in the theory; and massless and
massive spin-3/2 modes (with two unequal masses) coming from the gravitino.
These assemble into a massless and a massive N=1 spin-2 multiplet. In critical
supergravity, the coefficients are tuned so that the spin-2 mode in the massive
multiplet becomes massless. In the supersymmetrised extensions of critical
gravity, the coefficients are chosen so that the massive modes lie in a
"window" of lowest energies E_0 such that these ghostlike fields can be
truncated by imposing appropriate boundary conditions at infinity, thus leaving
just positive-norm massless supergravity modes.Comment: 29 page
Nonlinear Realization of Spontaneously Broken N=1 Supersymmetry Revisited
This paper revisits the nonlinear realization of spontaneously broken N=1
supersymmetry. It is shown that the constrained superfield formalism can be
reinterpreted in the language of standard realization of nonlinear
supersymmetry via a new and simpler route. Explicit formulas of actions are
presented for general renormalizable theories with or without gauge
interactions. The nonlinear Wess-Zumino gauge is discussed and relations are
pointed out for different definitions of gauge fields. In addition, a general
procedure is provided to deal with theories of arbitrary Kahler potentials.Comment: 1+18 pages, LaTe
T-duality and Actions for Non-BPS D-branes
We employ T-duality to restrict the tachyon dependence of effective actions
for non-BPS D-branes. For the Born-Infeld part the criteria of T-duality and
supersymmetry are satisfied by a simple extension of the D-brane Born-Infeld
action.Comment: Latex, 11 page
Tensor hierarchies, Borcherds algebras and E11
Gauge deformations of maximal supergravity in D=11-n dimensions generically
give rise to a tensor hierarchy of p-form fields that transform in specific
representations of the global symmetry group E(n). We derive the formulas
defining the hierarchy from a Borcherds superalgebra corresponding to E(n).
This explains why the E(n) representations in the tensor hierarchies also
appear in the level decomposition of the Borcherds superalgebra. We show that
the indefinite Kac-Moody algebra E(11) can be used equivalently to determine
these representations, up to p=D, and for arbitrarily large p if E(11) is
replaced by E(r) with sufficiently large rank r.Comment: 22 pages. v2: Published version (except for a few minor typos
detected after the proofreading, which are now corrected
Deep Chronnectome Learning via Full Bidirectional Long Short-Term Memory Networks for MCI Diagnosis
Brain functional connectivity (FC) extracted from resting-state fMRI
(RS-fMRI) has become a popular approach for disease diagnosis, where
discriminating subjects with mild cognitive impairment (MCI) from normal
controls (NC) is still one of the most challenging problems. Dynamic functional
connectivity (dFC), consisting of time-varying spatiotemporal dynamics, may
characterize "chronnectome" diagnostic information for improving MCI
classification. However, most of the current dFC studies are based on detecting
discrete major brain status via spatial clustering, which ignores rich
spatiotemporal dynamics contained in such chronnectome. We propose Deep
Chronnectome Learning for exhaustively mining the comprehensive information,
especially the hidden higher-level features, i.e., the dFC time series that may
add critical diagnostic power for MCI classification. To this end, we devise a
new Fully-connected Bidirectional Long Short-Term Memory Network (Full-BiLSTM)
to effectively learn the periodic brain status changes using both past and
future information for each brief time segment and then fuse them to form the
final output. We have applied our method to a rigorously built large-scale
multi-site database (i.e., with 164 data from NCs and 330 from MCIs, which can
be further augmented by 25 folds). Our method outperforms other
state-of-the-art approaches with an accuracy of 73.6% under solid
cross-validations. We also made extensive comparisons among multiple variants
of LSTM models. The results suggest high feasibility of our method with
promising value also for other brain disorder diagnoses.Comment: The paper has been accepted by MICCAI201
Domain walls and instantons in N=1, d=4 supergravity
We study the supersymmetric sources of (multi-) domain-wall and (multi-)
instanton solutions of generic N=1, d=4 supergravities, that is: the
worldvolume effective actions for said supersymmetric topological defects. The
domain-wall solutions naturally couple to the two 3-forms recently found as
part of the N=1, d=4 tensor hierarchy (i.e. they have two charges in general)
and their tension is the absolute value of the superpotential section L. The
introduction of sources (we study sources with finite and vanishing thickness)
is equivalent to the introduction of local coupling constants and results in
dramatic changes of the solutions. Our results call for a democratic
reformulation of N=1,d=4 supergravity in which coupling constants are,
off-shell, scalar fields. The effective actions for the instantons are always
proportional to the coordinate orthogonal to the twist-free embedding of the
null-geodesic (in the Wick-rotated scalar manifold) describing the instanton.
We show their supersymmetry and find the associated supersymmetric (multi-)
instanton solutions.Comment: 34 pages, 4 figures, references adde
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