459 research outputs found
Association of health literacy with obesity and overweight among arabic secondary school students in Kuala Lumpur and Putrajaya, Malaysia
Background: Overweight and obesity among adolescents is considered an epidemic in both developed and developing countries. There is still limited study on the health literacy as a determinant of overweight and obesity in adolescents.The aims of this study was to determine the association of health literacy with overweight and obesity.
Methods: This was a cross-sectional study among Arabic secondary school students in Kuala Lumpur and Putrajaya. Health literacy was measured using the Newest Vital Sign (NVS) questionnaire. Limited health literacy was defined as the NVS score of 0 to 3. Body weight and height were measured twice by standard methods and the mean of these two measurements was used in the calculation of body mass index. Overweight and obesity classification were based on the World Health Organization criteria. Chi-square test and multivariate binary logistic regression were performed using IBM-SPSS version 21.0.
Results: A total of 202 out of 250 students involved in this study giving the response rate as 81.0%. The percentage of overweight and obesity among the respondents was 21.3% and 6.9% respectively. Respondents with limited health literacy was 51.5%. Those with limited health literacy was almost 2 times higher (AOR = 1.963, 95%CI: 1.010, 3.816) to have overweight and obesity as compared to adequate health literacy.
Conclusion: The prevalence of overweight and obesity was high among the study population. Limited health literacy is a predictor of overweight and obesity. Improving health literacy should be considered in obesity and overweight intervention
Liquid chromatography - tandem mass spectroscopic method for the determination Of zerumbone in human plasma and its application to Pharmacokinetics
A rapid, sensitive, specific and selective LC-MS/MS method for the determination of zerumbone (ZER) in human plasma using 2,4-diamino-6-(4-methoxyphenyl)-1,3,5-triazine (DMTZ) as an internal standard (IS) has been developed and validated. ZER was chromatographed on C8 column using a mobile phase of acetonitrile/water (80:20, v/v) at a flow rate of 0.25 ml min(-1) . Quantitation was achieved using ESI+ interface, employing multiple reaction monitoring (MRM) mode at m/z 219 > 81 and 218 > 134 for ZER and IS, respectively. The calibration standards were linear over a range of 5-3000 ng ml(-1) (r(2)=0.9994) with an LLOQ of 5 ng ml(-1) (RSD %; 11.4% and bias%; 9.5%). Intra- and inter-day precision of ZER assay ranged from 0.18 to 3.56% with accuracy (bias) that varied between -5.09 and 4.3%, demonstrating good precision and accuracy. Recoveries of ZER and the IS from human plasma were above 85%. The developed method was validated for the determination of ZER in rat plasma. Linearity, stability of ZER and the ME on rat plasma were discussed. The applicability of the developed method was demonstrated by measuring ZER in rat plasma samples following intravenous and intraperitoneal administration of ZER prepared in hydroxypropyl-β-cyclodextrin (HPβCD) and sodium carboxymethyl cellulose (CMC), respectively, in 20 mg kg(-1) and this study indicated a clear significant difference (p<0.05) in pharmacokinetic parameters of ZER in ZER/HPβCD complex compared with ZER in CMC preparation
Effect of Graded Substitution Levels of Pigeon Pea (Cajanus Cajan) Leaf Meal for Berseem Leaf Meal on Broiler Performance
The main object of this study was to assess the productive and physiological responses of broiler chickens to dietary Pigeon Pea (Cajanus cajan) Leaf Meal (PPLM) as an ingredient. 200 day-old, unsexed Ross (303) broiler chicks were used as experimental birds; they were distributed to (5x10x4) following the completely randomized design (CRD). Experimental diets were formulated to (0.0%, 2.5%, 5.0%, 7.5% and 10.0% PPLM), at the expense of alfalfa meal which was included at 10.0% in the control diet. Feed and water were provided ad labium. Experimental period lasted for 7 weeks. Results revealed that there was a significant difference (P<0.05) in feed intake between level (2.5% - 5.0%), PPLM and control. There was no significant difference in total body weight gain. Feed conversion ratio (FCR) results showed that all birds fed PPLM were lagging after control, no significant difference detected between control and 5.0% PPLM. In conclusion the study showed that Pigeon pea (Cajanus cajan) leaf meal could be included in broiler diets at level 2.5-5.0% without any adverse effects on broiler performance
Characterization of the inclusion complex of zerumbone with hydroxypropyl--cyclodextrin
In this paper we investigated the inclusion complexation between zerumbone (ZER) and hydroxylpropyl-
-cyclodextrin (HPCD) at four different temperatures: 293–318 ◦K. The thermodynamic parameters
(H, S and G) for the formation of the complex were obtained from the van’t Hoff equation. The
complex with HPCD was characterized by differential scanning calorimetry (DSC), X-ray diffractometry
(XRD), Fourier transform infrared spectroscopy (FT-IR), and molecular modeling using PM6. The solubility
of ZER was enhanced >30 fold after complexation. Calculations show that ZER penetrates completely into
the cavity of HPCD. The complex retained its cytotoxic activity as shown by in vitro cell survival assay on
human cervical cancer (Hela), breast cancer (MCF7 and MDA-MB 231) and human leukemic (CEMss) cell
lines. HPCD is, therefore, a suitable encapsular capable of forming thermodynamically stable complex
with ZER for save delivery of the compound as an anticancer drug in the future
Modeling irregular time series with continuous recurrent units
Recurrent neural networks (RNNs) are a popular choice for modeling sequential data. Modern RNN architectures assume constant time-intervals between observations. However, in many datasets (e.g. medical records) observation times are irregular and can carry important information. To address this challenge, we propose continuous recurrent units (CRUs) {–} a neural architecture that can naturally handle irregular intervals between observations. The CRU assumes a hidden state, which evolves according to a linear stochastic differential equation and is integrated into an encoder-decoder framework. The recursive computations of the CRU can be derived using the continuous-discrete Kalman filter and are in closed form. The resulting recurrent architecture has temporal continuity between hidden states and a gating mechanism that can optimally integrate noisy observations. We derive an efficient parameterization scheme for the CRU that leads to a fast implementation f-CRU. We empirically study the CRU on a number of challenging datasets and find that it can interpolate irregular time series better than methods based on neural ordinary differential equations
Electrosprayed core-shell nanoparticles of PVP and shellac for furnishing biphasic controlled release of ferulic acid
Coaxial electrospraying was explored to organize polymer excipients in a core-shell manner for providing biphasic controlled release of active ingredient. With ferulic acid (FA) as a model drug, and shellac and polyvinylpyrrolidone (PVP) as the core and shell polymeric matrices, core-shell nanoparticles were successfully fabricated. A series of tests were carried out to characterize the prepared core-shell nanoparticles and also the nanoparticles prepared using a single fluid electrospraying of the shell or core fluids alone. The core-shell nanoparticles had an average diameter of 530 ± 80 nm with clear core-shell structure. The contained FA was converted to an amorphous state both in the core and the shell parts due to the favorable hydrogen bonding between the components. In vitro dissolution tests demonstrated that the core-shell nanoparticles were able to provide the desired biphasic drug-controlled release profiles. Coaxial electrospraying is a useful tool for the development of novel nanodrug delivery systems from polymers
Effects of mixed cropping with cowpea and nitrogen source on growth and yield of sunflower (Helianthus annuus L.)
Field experiments were conducted during winter (2011/12) and summer (2012/13) seasons. The objective of the study was to examine the effects of mixed cropping with cowpea, nitrogen and chicken manure on growth and yield of sunflower. Randomized complete block design with four replicates was used. The experiment comprised 8 treatments; two sunflower cultivars namely, Hysun33 and Damazin-1, and three nitrogen sources viz: mixed cropping with cowpea, urea (43kgN/ha), chicken manure (5t/ha) plus control. Results showed that the two cultivars were significantly different in plant height, days to 50% flowering, 1000-seed weight and empty seed percentage in both seasons. Hysun33 had taller plants, late to flower, heavier seeds and lower empty seeds percentage than Damazin-1. They were also significantly different in LAI, head diameter, number of filled seeds/ head and total yield in the summer season only. Fertilizers significantly influenced plant height and stem diameter in both seasons. In the winter season, however, fertilizers had significantly affected LAI, days to 50% flowering, head diameter, number of filled seeds/head and total yield. Chicken manure resulted in the tallest plants and largest stem diameter in both seasons. Chicken manure expressed the largest LAI, biggest head diameter, highest number of filled seeds/head and highest total yield. The three-way interaction(seasonx fertilizerx cultivar) showed significant effects on percentage of empty seeds and total yield. The highest total yield was obtained by Hysun33 in the summer season when chicken manure was applied. The mean total yield of the summer season was higher than that of the winter season. To obtain high total yield of sunflower, it is recommended that sowing should be commenced during the summer season and chicken manure should be applied at the rate of 5 t/ha for both Hysun33 and Damazin-
A Phase Feedback Based Extended Space-Time Block Code for Enhancement of Diversity
This is a conference paper [© IEEE]. It is also available at: http://ieeexplore.ieee.org/ Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.In this paper we propose a generalization of extended orthogonal space-time block codes (EO-STBCs) for MIMO (multi-input/multi-output) channels using four transmit antennas for quasi-static flat fading channels. Since full rate and complex orthogonal space-time block codes (STBCs) do not exist for more than two transmit antennas, we propose a feedback based STBC scheme. In this scheme, phases of certain symbols are rotated according to the feedback from the receiver which is equivalent to rotating the phases of the corresponding channel coefficients. Simulation results show that this rotation phase feedback method achieves a satisfactory performance and outperforms the previous closed-loop space-time block codes, even when the feedback is quantized
Sudanese Medical Students and Scientific Research
Background: Most of developing countries face problems in assessment of their public health practices. Gain of this knowledge is orchestrated by research. Medical students can play an essential role in improving public database.Objective: to explore knowledge, attitude and skills of medical students in the Faculty of Medicine and Health Sciences (FMHS), Omdurman Islamic University (OIU) towards research.Materials and Methods: This is a descriptive, analytical, cross-sectional, institution-based study. A total of 442 students, equally from each batch participated in the study. Equal numbers of male andfemale were considered to eliminate gender and seniority bias. Structured pretested questionnaire was used for data collection. Data collected were fed to Statistical Package for Social Sciences(SPSS) version 15. Means, standard deviation and correlations were done where appropriate. Statistical significance was taken at P =0.05.Results: The mean knowledge score was 37% and attitude was positive in 77.1% of the students. Only 18.3% had attended research methodology workshop. The rate of internet navigation is directly proportional to the social class. Only 14.7% knew the engines used for finding medical literature.Conclusion: The low knowledge score is due to lack of application of research in the academic curriculum; however, the students have a fairly positive attitude. The knowledge is expected to improve with the intended policy to include practical research in the curriculum.Key Words: Public health, academic curriculum, Suda
- …
