How Well Does AdS/QCD Describe QCD?

AdS/QCD is an extra-dimensional approach to modeling hadronic physics, motivated by the AdS/CFT correspondence in string theory. AdS/QCD models are often more accurate than would have been expected at energies below a few GeV. We address the question of why these models are so successful, and respond to some of the criticisms that have been waged against these models.Comment: To appear in proceedings of Crossing the Boundaries: Gauge Dynamics at Strong Coupling (Shifmania), Minnesota, May 14-17, 2009. 12 pages, 2 eps figure

Supernovae as a probe of particle physics and cosmology

It has very recently been demonstrated by Csaki, Kaloper and Terning (CKT) that the faintness of supernovae at high redshift can be accommodated by mixing of a light axion with the photon in the presence of an intergalactic magnetic field, as opposed to the usual explanation of an accelerating universe by a dark energy component. In this paper we analyze further aspects of the CKT mechanism and its generalizations. The CKT mechanism also passes various cosmological constraints from the fluctuations of the CMB and the formation of structure at large scales, without requiring an accelerating phase in the expansion of the Universe. We investigate the statistical significance of current supernova data for pinning down the different components of the cosmological energy-momentum tensor and for probing physics beyond the standard models.Comment: 17 pages, LaTeX, 4 figures; v2: typos corrected, minor changes, references added; v3: updated figures, details regarding fits include

Conformal Symmetry and the Three Point Function for the Gravitational Axial Anomaly

This work presents a first study of a radiative calculation for the gravitational axial anomaly in the massless Abelian Higgs model. The two loop contribution to the anomalous correlation function of one axial current and two energy-momentum tensors, , is computed at an order that involves only internal matter fields. Conformal properties of massless field theories are used in order to perform the Feynman diagram calculations in the coordinate space representation. The two loop contribution is found not to vanish, due to the presence of two independent tensor structures in the anomalous correlator.Comment: 34 pages, 5 figures, RevTex, Minor changes, Final version for Phys. Rev.

Clustering and Alignment of Polymorphic Sequences for HLA-DRB1 Genotyping

Located on Chromosome 6p21, classical human leukocyte antigen genes are highly polymorphic. HLA alleles associate with a variety of phenotypes, such as narcolepsy, autoimmunity, as well as immunologic response to infectious disease. Moreover, high resolution genotyping of these loci is critical to achieving long-term survival of allogeneic transplants. Development of methods to obtain high resolution analysis of HLA genotypes will lead to improved understanding of how select alleles contribute to human health and disease risk. Genomic DNAs were obtained from a cohort of n = 383 subjects recruited as part of an Ulcerative Colitis study and analyzed for HLA-DRB1. HLA genotypes were determined using sequence specific oligonucleotide probes and by next-generation sequencing using the Roche/454 GSFLX instrument. The Clustering and Alignment of Polymorphic Sequences (CAPSeq) software application was developed to analyze next-generation sequencing data. The application generates HLA sequence specific 6-digit genotype information from next-generation sequencing data using MUMmer to align sequences and the R package diffusionMap to classify sequences into their respective allelic groups. The incorporation of Bootstrap Aggregating, Bagging to aid in sorting of sequences into allele classes resulted in improved genotyping accuracy. Using Bagging iterations equal to 60, the genotyping results obtained using CAPSeq when compared with sequence specific oligonucleotide probe characterized 4-digit genotypes exhibited high rates of concordance, matching at 759 out of 766 (99.1%) alleles. © 2013 Ringquist et al

Black Diamonds at Brane Junctions

We discuss the properties of black holes in brane-world scenarios where our universe is viewed as a four-dimensional sub-manifold of some higher-dimensional spacetime. We consider in detail such a model where four-dimensional spacetime lies at the junction of several domain walls in a higher dimensional anti-de Sitter spacetime. In this model there may be any number p of infinitely large extra dimensions transverse to the brane-world. We present an exact solution describing a black p-brane which will induce on the brane-world the Schwarzschild solution. This exact solution is unstable to the Gregory-Laflamme instability, whereby long-wavelength perturbations cause the extended horizon to fragment. We therefore argue that at late times a non-rotating uncharged black hole in the brane-world is described by a deformed event horizon in p+4 dimensions which will induce, to good approximation, the Schwarzschild solution in the four-dimensional brane world. When p=2, this deformed horizon resembles a black diamond and more generally for p>2, a polyhedron.Comment: 13 pages, 1 figure, latex, JHEP.cl

Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity

Macrophages resident in different organs express distinct genes, but understanding how this diversity fits into tissue-specific features is limited. Here, we show that selective expression of coagulation factor V (FV) by resident peritoneal macrophages in mice promotes bacterial clearance in the peritoneal cavity and serves to facilitate the well-known but poorly understood macrophage disappearance reaction. Intravital imaging revealed that resident macrophages were nonadherent in peritoneal fluid during homeostasis. Bacterial entry into the peritoneum acutely induced macrophage adherence and associated bacterial phagocytosis. However, optimal control of bacterial expansion in the peritoneum also required expression of FV by the macrophages to form local clots that effectively brought macrophages and bacteria in proximity and out of the fluid phase. Thus, acute cellular adhesion and resident macrophage-induced coagulation operate independently and cooperatively to meet the challenges of a unique, open tissue environment. These events collectively account for the macrophage disappearance reaction in the peritoneal cavity

Assessment of recent outbreaks of Dickeya sp (syn. Erwinia chrysanthemi) slow wilt in potato crops in Israel

Suspected Dickeya sp. strains were obtained from potato plants and tubers collected from commercial plots. The disease was observed on crops of various cultivars grown from seed tubers imported from the Netherlands during the spring seasons of 2004-2006, with disease incidence of 2-30% ( 10% in average). In addition to typical wilting symptoms on the foliage, in cases of severe infection, progeny tubers were rotten in the soil. Six strains were characterised by biochemical, serological and PCR amplification. All tests verified the strains as Dickeya sp. The repPCR and the biochemical assays showed that the strains isolated from blackleg diseased plants in Israel were very similar, if not identical to strains isolated from Dutch seed potatoes, suggesting that the infection in Israel originated from the Dutch seed. The strains were distantly related to D. dianthicola strains, typically found in potatoes in Western Europe, and were similar to biovar 3 D. dadanti or D. zeae. This is the first time that the presence of biovar 3 strains in potato in the Netherlands is described. One of the strains was used for pathogenicity assays on potato cvs Nicola and Mondial. Symptoms appeared 2 to 3 days after stem inoculation, and 7 to 10 days after soil inoculation. The control plants treated with water, or plants inoculated with Pectobacterium carotovorum, did not develop any symptoms with either method of inoculation. The identity of Dickeya sp. and P. carotovorum re- isolated from inoculated plants was confirmed by PCR and ELISA

On the Evaluation of Gluon Condensate Effects in the Holographic Approach to QCD

In holographic QCD the effects of gluonic condensate can be encoded in a suitable deformation of the 5D metric. We develop two different methods for the evaluation of first order perturbative corrections to masses and decay constants of vector resonances in 5D Hard-Wall models of QCD due to small deformations of the metric. They are extracted either from a novel compact form for the first order correction to the vector two-point function, or from perturbation theory for vector bound-state eigenfunctions: the equivalence of the two methods is shown. Our procedures are then applied to flat and to AdS 5D Hard-Wall models; we complement results of existing literature evaluating the corrections to vector decay constant and to two-pion-one-vector couplings: this is particularly relevant to satisfy the sum rules. We concentrate our attention on the effects for the Gasser-Leutwyler coefficients; we show that, as in the Chiral Quark model, the addition of the gluonic condensate improves the consistency, the understanding and the agreement with phenomenology of the holographic model.Comment: 23 pages, three figures, sign error in pion wave function fixed, numerical analysis extended, general conclusions unchange

Little Technicolor

Inspired by the AdS/CFT correspondence, we show that any G/H symmetry breaking pattern can be described by a simple two-site moose diagram. This construction trivially reproduces the CCWZ prescription in the context of Hidden Local Symmetry. We interpret this moose in a novel way to show that many little Higgs theories can emerge from ordinary chiral symmetry breaking in scaled-up QCD. We apply this reasoning to the simple group little Higgs to see that the same low energy degrees of freedom can arise from a variety of UV complete theories. We also show how models of holographic composite Higgs bosons can turn into brane-localized little technicolor theories by "integrating in" the IR brane.Comment: 26 pages, 2 figures; v2: references added; v3: added section on vacuum alignment to match JHEP versio