Effect of Paclobutrazol on the Reproductive System of Semperula maculata

Among all the biological processes in the living organisms, reproduction is a important life process for survival and continuation of every race and species on the earth. Present study was designed to investigate the effect of Paclobutrazol on the reproductive system of terrestrial slug Semperula maculata. The animals were exposed for pre-determined median lethal concentration (3362.15 ppm) of Paclobutrazol upto 96 hours. Histological and biochemical estimation especially protein content from selected reproductive organs were carried out against effective dose of PBZ. Obtained results were interpreted for reproduction and potency.&nbsp

Comparative Antibacterial Study of Different Extracts of Nyctanthes Arbortristis

Nyctanthes arbortristis (N. Arbortristis) is one of the most useful traditional medicinal plant in India. The present review is to focus on the potential of phyto-chemicals and pharmacological activity of plant N. Arbortristis. Phyto-chemicals like flavanoid, glycoside, oleanic acid, essential oils, tannic acid, carotene, friedeline, lupeol, glucose, benzoic acid have been reported for significant hair tonic, hepatoprotective, anti-leishmaniasis, anti-viral, antifungal, anti-pyretic, anti-histaminic, anti-malerial, anti-bacterial, anti-inflammatory and anti-oxidant activities of night jasmine and emphasizes the need for further exploring available information. The aqueous extract was prepared using distilled water by decoction method. The dilutions of ethyl acetate, ethanolic, methanolic and chloroform extracts of Nyctanthes arbortristis was poured in the well with the help of sterile syringe needle in each, petri plate were placed in a refrigerator for 5 minutes to allow diffusion; later the petri plates were incubated in inverted position at 37° C for 24 hours in incubator, after 24 hours, the zone of inhibition was observed and diameter in mm was measured and recorded. This study represents that chloroform extract give higher zone of inhibition that is 15mm. Methanolic extract gives 14mm, ethanolic and ethyl acetate give 11 mm and 12mm respectively. Lowest zone of inhibition form by aqueous extract forms 10 mm. From this study, it can be concluded that chloroform extract gives better zone of inhibition comparing with ethyl acetate, ethanolic, methanolic and aqueous extract of Nyctanthes arbortristis

A Validated Stability-Indicating RP-HPLC Method for Quantification of Glycyrrhizic Acid and Piperine in Polyherbal Formulations: Quantification of Glycyrrhizic Acid and Piperine: A Stability-Indicating RP-HPLC Method

Glycyrrhizic acid and piperine are frequently used in conjunction with other therapies to treat a variety of disorders, although both medications have low water solubility and photosensitivity issues. The objective of this study is to develop a Reverse-phase High-Performance Liquid Chromatography (RP-HPLC) method, known for its selectivity, precision, sensitivity, and accuracy. This method is intended for the quantification of phytoconstituents in formulating polyherbal tablets as well as in certain Ayurvedic formulations. Glycyrrhizic acid and piperine were successfully separated by liquid chromatography using the phenomenex Luna C-18 column and an isocratic elution mode with a mobile phase made up of a combination of methanol and HPLC grade water. A photodiode array (PDA) detector was used to determine the retention times for glycyrrhizic acid and piperine, which were determined to be 2.06 minutes and 9.0 minutes and the method was found to be accurate (>95%) and precise (%RSD < 25) respectively. The method was established to be specific for the quantification of glycyrrhizic acid and piperine in in-house polyherbal tablets and some Ayurvedic formulations. Additionally, both phytoconstituents stress degradation studies were examined, and in the presence of degradation products, good drug peak separation was observed. Thus, glycyrrhizic acid and piperine may be regularly estimated in vitro and in vivo using this method

Case Study on Patient Profile of Renal Failure

Identification and selection of patient suffering from Renal Failure- To explore the patient treatment for renal failure, its catogries either acute or chronic, then to study about the haematological, renal or biochemical profile of the patient and the family history. The detailed study about the pathological test performed by the patient.  Then, the medications administered to the patient. The future treatment to be carried out either dialysis or kidney transplantation

Heat Transfer Characteristics of CuO-Water Nanofluids Jet Impingement on a Hot Surface

In present study, an experimental investigation has been carried out to analyze the heat transfer characteristics of CuO-water nanofluids jets on a hot surface. A rectangular stainless steel foil (AISI-304, 0.15 mm thick) is used as a test surface is electrically heated to obtain the required initial temperature. The distribution of heat flux on the target surface is evaluated from the recorded thermal images during transient cooling. The effect of nanoparticle concentration and Reynolds number of the nanofluids jet impingement heat transfer characteristics is studied. Tests were performed for an initial surface temperature of 500°C, Reynolds number (5000≤Re≤13000), CuO-water nanofluids concentration (Φ= 0.15%, 0.6%) and nozzle to plate distance was l/d= 4.</jats:p