1,236 research outputs found
Decoherence in a fermion environment: Non-Markovianity and Orthogonality Catastrophe
We analyze the non-Markovian character of the dynamics of an open two-level
atom interacting with a gas of ultra-cold fermions. In particular, we discuss
the connection between the phenomena of orthogonality catastrophe and Fermi
edge singularity occurring in such a kind of environment and the memory-keeping
effects which are displayed in the time evolution of the open system
Vortex entanglement in Bose-Einstein condensates coupled to Laguerre-Gauss beams
We study the establishment of vortex entanglement in remote and weakly
interacting Bose Einstein condensates. We consider a two-mode photonic resource
entangled in its orbital angular momentum (OAM) degree of freedom and, by
exploiting the process of light-to-BEC OAM transfer, demonstrate that such
entanglement can be efficiently passed to the matter-like systems. Our proposal
thus represents a building block for novel low-dissipation and long-memory
communication channels based on OAM. We discuss issues of practical
realizability, stressing the feasibility of our scheme and present an operative
technique for the indirect inference of the set vortex entanglement.Comment: 10 pages, 7 figures, RevTex
An association of boswellia, betaine and myo-inositol (Eumastós) in the treatment of mammographic breast density. A randomized, double-blind study
Mammographic breast density is a recognized risk factor for breast cancer. The causes that lead to the proliferation of the glandular breast tissue and, therefore, to an increase of breast density are still unclear. However, a treatment strategy to reduce the mammary density may bring about very relevant clinical outcomes in breast cancer prevention. Myo-inositol is a six-fold alcohol of cyclohexane, has already been proved to modulate different pathways: inflammatory, metabolic, oxidative and endocrine processes, in a wide array of human diseases, including cancer and the genesis of mammary gland and breast diseases, like fibrosis, as well as metabolic and endocrine cues. Similarly, boswellic acid and betaine (three-methyl glycine) both inhibit inflammation and exert protective effects on breast physiology. Based on this scientific background, we hypothesized that a combination including, boswellic acid, betaine and myo-inositol would be able to reduce breast density working on different pathways.OBJECTIVE: Mammographic
breast density is a recognized risk factor for
breast cancer. The causes that lead to the proliferation
of the glandular breast tissue and,
therefore, to an increase of breast density are
still unclear. However, a treatment strategy to
reduce the mammary density may bring about
very relevant clinical outcomes in breast cancer
prevention.
Myo-inositol is a six-fold alcohol of cyclohexane,
has already been proved to modulate different
pathways: inflammatory, metabolic, oxidative
and endocrine processes, in a wide array of human
diseases, including cancer and the genesis
of mammary gland and breast diseases, like fibrosis,
as well as metabolic and endocrine cues.
Similarly, boswellic acid and betaine (threemethyl
glycine) both inhibit inflammation and exert
protective effects on breast physiology.
Based on this scientific background, we hypothesized
that a combinat ion including,
boswellic acid, betaine and myo-inositol would
be able to reduce breast density working on
different pathways.
PATIENTS AND METHODS: In this study,
seventy-six premenopausal women were randomly
assigned to the placebo and the experimental
drug arms (Eumastós®) for six months.
RESULTS: After 6 months of treatment, statistically
significant difference between the two
groups was recorded on the breast density reduction
(60% vs. 9%), using mammographic as
well as ultrasound examination.
CONCLUSIONS: Preliminary data collected
here with support the starting assumptions,that the association comprising boswellic acid,
betaine and myo-inositol significantly reduces
mammary density, providing the first evidence
for a new and safe approach for the management
of mammographic density treatment
Critical assessment of two-qubit post-Markovian master equations
A post-Markovian master equation has been recently proposed as a tool to
describe the evolution of a system coupled to a memory-keeping environment [A.
Shabani and D. A. Lidar, Phys. Rev. A 71, 020101 (R) (2005)]. For a single
qubit affected by appropriately chosen environmental conditions, the
corresponding dynamics is always legitimate and physical. Here we extend such
situation to the case of two qubits, only one of which experiences the
environmental effects. We show how, despite the innocence of such an extension,
the introduction of the second qubit should be done cum grano salis to avoid
consequences such as the breaking of the positivity of the associated dynamical
map. This hints at the necessity of using care when adopting phenomenologically
derived models for evolutions occurring outside the Markovian framework.Comment: 7 pages, 1 figure, RevTeX4. Close to published versio
Orthogonality catastrophe and decoherence in a trapped-fermion environment
The Fermi-edge singularity and the Anderson orthogonality catastrophe describe the universal physics which occurs when a Fermi sea is locally quenched by the sudden switching of a scattering potential, leading to a brutal disturbance of its ground state. We demonstrate that the effect can be seen in the controllable domain of ultracold trapped gases by providing an analytic description of the out-of-equilibrium response to an atomic impurity, both at zero and at finite temperature. Furthermore, we link the transient behavior of the gas to the decoherence of the impurity, and to the degree of the non-Markovian nature of its dynamics
Avaliação do efeito do fipronil sobre a germinação, número de perfilhos e produção de massa seca de Paspalum regnellii.
A pesquisa foi desenvolvida na EMBRAPA Pecuária Sudeste, São Carlos, SP, com o objetivo de avaliar os efeitos do tratamento de sementes de Paspalum Regnellii com o inseticida Fipronil 250g/L (Standak), sobre a germinação, número de perfilhos e massa seca. As dosagens aplicadas foram 0, 10, 20, 40, 80 mL p.c./ha. O delineamento utilizado foi de blocos completos ao acaso, com quatro repetições. As sementes foram semeadas em canteiros de 1,5m x 1,5 m, com espaçamento de 15 cm entre linhas. A germinação foi afetada positivamente por todas as doses de fipronil. O número de perfilhos foi afetado pelas doses, sendo as doses de 10 e 20 mL, as que apresentaram melhores resultados. As doses não afetaram a produção de massa seca. A dosagem de 10 mL apresentou melhores resultados que as doses recomendadas pelo fabricante
Percutaneous Tibial Nerve Stimulation for Treatment of Idiopathic Faecal Incontinence: Mid-term Results from a Single Center
Abstract
Objective: Percutaneous tibial nerve stimulation is a recent and minimally invasive treatment for faecal
incontinence (FI). The aim of this study is to evaluate the mid-term results in patients with idiopathic faecal
incontinence (IFI).
Methods: Fifty one patients (42 female and 9 male) were prospectively recruited. Patients were treated twice a
week for 6 weeks as per study protocol. We have assessed the degree of fecal incontinence using the Cleveland
Clinic faecal incontinence (CCF-FI) score at baseline, at 6 weeks, at 6 months and at 1 year. Also the anorectal
manometric data (mean resting pressure (MRP), squeeze pressure (SP) and, rectal sensation) at baseline, at 6
weeks and at 6 months have been evaluated.
Results: The median CCF-FI score was significantly decreased from an initial baseline value from 12 to 7 at 6
weeks, 3 at 6 months and, 3 at 1 year (respectively: 1st interquartile 4.5, 1, 0 vs 10; 3rd interquartile 9, 5, 5 vs 14.5,
p = 0.0001). Anorectal manometry showed an improvement of the internal (resting pressure, MRP) and the external
sphincters (squeeze pressure, SP) at 6 months compared to the baseline and 6 weeks by PTNS, while, RP and SP
at 6 months was greater than at baseline and 6 weeks (p = 0.004 and p = 0.002 respectively).
Conclusions: This study demonstrates that stimulation of the posterior tibial nerve could be an excellent
procedure for the treatment of IFI. The stimulation of the posterior tibial nerve can improve the fecal continence
(CCF-FI score) in the short term and this improvement is maintained after 1 year of follow-up without treatmen
Acetic Acid Bacteria: Physiology and Carbon Sources Oxidation
Acetic acid bacteria (AAB) are obligately aerobic bacteria within the family Acetobacteraceae, widespread in sugary, acidic and alcoholic niches. They are known for their ability to partially oxidise a variety of carbohydrates and to release the corresponding metabolites (aldehydes, ketones and organic acids) into the media. Since a long time they are used to perform specific oxidation reactions through processes called “oxidative fermentations”, especially in vinegar production. In the last decades physiology of AAB have been widely studied because of their role in food production, where they act as beneficial or spoiling organisms, and in biotechnological industry, where their oxidation machinery is exploited to produce a number of compounds such as l-ascorbic acid, dihydroxyacetone, gluconic acid and cellulose. The present review aims to provide an overview of AAB physiology focusing carbon sources oxidation and main products of their metabolism
TP53 and p16INK4A, but not H-KI-Ras, are involved in tumorigenesis and progression of pleomorphic adenomas.
The putative role of TP53 and p16INK4A tumor suppressor genes and Ras oncogenes in the development and progression of salivary
gland neoplasias was studied in 28 cases of pleomorphic adenomas (PA), 4 cases of cystic adenocarcinomas, and 1 case of
carcinoma ex-PA. Genetic and epigenetic alterations in the above genes were analyzed by Polymerase Chain Reaction/Single
Strand Conformational Polymorphism (PCR/SSCP) and sequencing and by Methylation Specific-PCR (MS-PCR). Mutations in TP53
were found in 14% (4/28) of PAs and in 60% (3/5) of carcinomas. Mutations in H-Ras and K-Ras were identified in4%(1/28) and7%
(2/28) of PAs, respectively. Only 20% (1/5) of carcinomas screened displayed mutations in K-Ras. p16INK4A promoter
hypermethylation was found in 14% (4/28) of PAs and 100% (5/5) carcinomas. All genetic and epigenetic alterations were detected
exclusively in the epithelial and transitional tumor components, and were absent in the mesenchymal parts. Our analysis suggests
that TP53 mutations and p16INK4A promoter methylation, but not alterations in the H-Ras and K-Ras genes, might be involved in the
malignant progression of PA into carcinoma. J. Cell. Physiol. 207: 654–659, 2006. 2006 Wiley-Liss, Inc
How carbon sources drive cellulose synthesis in two Komagataeibacter xylinus strains
Bacterial cellulose synthesis from defined media and waste products has attracted increasing interest in the circular economy context for sustainable productions. In this study, a glucose dehydrogenase-deficient Δgdh K2G30 strain of Komagataeibacter xylinus was obtained from the parental wild type through homologous recombination. Both strains were grown in defined substrates and cheese whey as an agri-food waste to assess the effect of gene silencing on bacterial cellulose synthesis and carbon source metabolism. Wild type K2G30 boasted higher bacterial cellulose yields when grown in ethanol-based medium and cheese whey, although showing an overall higher d-gluconic acid synthesis. Conversely, the mutant Δgdh strain preferred d-fructose, d-mannitol, and glycerol to boost bacterial cellulose production, while displaying higher substrate consumption rates and a lower d-gluconic acid synthesis. This study provides an in-depth investigation of two K. xylinus strains, unravelling their suitability for scale-up BC production
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