Relating the Chondrocyte Gene Network to Growth Plate Morphology: From Genes to Phenotype

During endochondral ossification, chondrocyte growth and differentiation is controlled by many local signalling pathways. Due to crosstalks and feedback mechanisms, these interwoven pathways display a network like structure. In this study, a large-scale literature based logical model of the growth plate network was developed. The network is able to capture the different states (resting, proliferating and hypertrophic) that chondrocytes go through as they progress within the growth plate. In a first corroboration step, the effect of mutations in various signalling pathways of the growth plate network was investigated

Analisis Tingkat Inflasi Terhadap Pertumbuhan Ekonomi di Indonesia

Stabilisasi harga menjadi salah satu acuan terjadinya pergeseran struktur perekonomia di Indonesia. Penelitian ini bertujuan untuk menganalisis tingkat inflasi yang diukur dengan indeks harga konsumen terhadap pertumbuhan ekonomi yang di ukur dengan nilai PDB di Indonesia. Selain ini variabel tingkat suku bunga dan pengeluaran pemerintah menjadi variabel eksogen untuk menganlisis hubungan inflasi dan PDB. Penelitian ini menggunakan data kuantitatif dengan time series selama 20 tahun yaitu tahun 2003 sampai 2022. Hasil penelitian menunjukan hubungan positif signifikan antar variabel eksogen dan endogen baik secara langsung atau melalui variabel antara. Hubungan antar variabel ini akan selalu berubah tergantung pada kondisi pasar dan kebijakan ekonomi yang berlaku pada waktu tertentu

Cultural Capital in the Economic Field : A Study of Relationships in an Art Market

In this study of an economic field and its relationships to a cultural field, we apply Pierre Bourdieu’s central concepts of economic capital, cultural capital, symbolic capital and field, and thus follow in a tradition that at the outset was considered to be post-structuralism, but which by Bourdieu later has been brought into the realm of realism. We have mapped relationships between the actors and thus the field structures that these relationships entail. The fields in which a segment of an art world is operating is represented in multi-dimensional figures which illustrate relationships and bonds between the different categories of organizations. Some of the business actors we have studied are engaging in cultural activities with a great deal of autonomy, others are connected to the cultural field in less active ways. In participating in the cultural field they are in different ways and to different extents accumulating symbolic capital including prestige and honor. The method we have applied is multiple correspondence analysis which was frequently used by Bourdieu

Periosteum Derived Cells in Skeletal Tissue Regeneration

status: Published onlin