ERTS-1 Views the Great Lakes Area

ERTS-1 study of mesoscale atmospheric phenomena associated with Great Lake

Contraceptive confidence and timing of first birth in Moldova: an event history analysis of retrospective data

Objectives: To test the contraceptive confidence hypothesis in a modern context. The hypothesis is that women using effective or modern contraceptive methods have increased contraceptive confidence and hence a shorter interval between marriage and first birth than users of ineffective or traditional methods. We extend the hypothesis to incorporate the role of abortion, arguing that it acts as a substitute for contraception in the study context.Setting: Moldova, a country in South-East Europe. Moldova exhibits high use of traditional contraceptive methods and abortion compared with other European countries.Participants: Data are from a secondary analysis of the 2005 Moldovan Demographic and Health Survey, a nationally representative sample survey. 5377 unmarried women were selected.Primary and secondary outcome measures: The outcome measure was the interval between marriage and first birth. This was modelled using a piecewise-constant hazard regression, with abortion and contraceptive method types as primary variables along with relevant sociodemographic controls.Results: Women with high contraceptive confidence (modern method users) have a higher cumulative hazard of first birth 36?months following marriage (0.88 (0.87 to 0.89)) compared with women with low contraceptive confidence (traditional method users, cumulative hazard: 0.85 (0.84 to 0.85)). This is consistent with the contraceptive confidence hypothesis. There is a higher cumulative hazard of first birth among women with low (0.80 (0.79 to 0.80)) and moderate abortion propensities (0.76 (0.75 to 0.77)) than women with no abortion propensity (0.73 (0.72 to 0.74)) 24?months after marriage.Conclusions: Effective contraceptive use tends to increase contraceptive confidence and is associated with a shorter interval between marriage and first birth. Increased use of abortion also tends to increase contraceptive confidence and shorten birth duration, although this effect is non-linear—women with a very high use of abortion tend to have lengthy intervals between marriage and first birth

Fatal injuries to car occupants: analysis of health and population data

Although this report was commissioned by the Department for Transport (DfT), the findings and recommendations are those of the authors and do not necessarily represent the views of the DfT. While the DfT has made every effort to ensure the information in this document is accurate, DfT does not guarantee the accuracy, completeness or usefulness of that information; and it cannot accept liability for any loss or damages of any kind resulting from reliance on the information or guidance this document contains

Using Taint Analysis and Reinforcement Learning (TARL) to Repair Autonomous Robot Software

It is important to be able to establish formal performance bounds for autonomous systems. However, formal verification techniques require a model of the environment in which the system operates; a challenge for autonomous systems, especially those expected to operate over longer timescales. This paper describes work in progress to automate the monitor and repair of ROS-based autonomous robot software written for an a-priori partially known and possibly incorrect environment model. A taint analysis method is used to automatically extract the data-flow sequence from input topic to publish topic, and instrument that code. A unique reinforcement learning approximation of MDP utility is calculated, an empirical and non-invasive characterization of the inherent objectives of the software designers. By comparing off-line (a-priori) utility with on-line (deployed system) utility, we show, using a small but real ROS example, that it's possible to monitor a performance criterion and relate violations of the criterion to parts of the software. The software is then patched using automated software repair techniques and evaluated against the original off-line utility.Comment: IEEE Workshop on Assured IEEE Workshop on Assured Autonomous Systems, May, 202

DEveloping a Complex Intervention for DEteriorating Patients using Theoretical Modelling (DECIDE study): study protocol

AIM: To develop a theory-based complex intervention (targeting nursing staff), to enhance enablers and overcome barriers to enacting expected behaviour when monitoring patients and responding to abnormal vital signs that signal deterioration. DESIGN: A mixed method design including structured observations on hospital wards, field notes, brief, un-recorded interviews and semi-structured interviews to inform the development of an intervention to enhance practice. METHODS: Semi-structured interviews will be conducted with nursing staff using a topic guide informed by the Theoretical Domains Framework. Semi-structured interviews will be transcribed verbatim and coded deductively into the 14 Theoretical Domains Framework domains and then inductively into 'belief statements'. Priority domains will be identified and mapped to appropriate behaviour change techniques. Intervention content and mode of delivery (how behaviour change techniques are operationalised) will be developed using nominal groups, during which participants (clinicians) will rank behaviour change techniques /mode of delivery combinations according to acceptability and feasibility. Findings will be synthesised to develop an intervention manual. DISCUSSION: Despite being a priority for clinicians, researchers and policymakers for two decades, 'sub-optimal care' of the deteriorating ward patient persists. Existing interventions have been largely educational (i.e., targeting assumed knowledge deficits) with limited evidence that they change staff behaviour. Staff behaviour when monitoring and responding to abnormal vital signs is likely influenced by a range of mediators that includes barriers and enablers. IMPACT: Systematically applying theory and evidence-based methods, will result in the specification of an intervention which is more likely to result in behaviour change and can be tested empirically in future research. This article is protected by copyright. All rights reserved

Aspects of bovine caesarean section associated with calf mortality, dam survival and subsequent fertility.

Bovine caesarean section is a common surgery performed by cattle practitioners yet evidence for justifying many aspects of the surgical procedure is lacking. Between 2001 and 2007, questionnaires were used to gather information on 103 cases of caesarean section performed in one, predominantly dairy, veterinary practice. The results showed that the 14-day cow survival rate was 80.6%, and of those surviving beyond this period, 55.4% carried another calf to term, 27.7% were culled due to infertility and 16.9% were culled due to other reasons. Variables associated with reduced 14-day dam mortality included exteriorising the uterus during surgery (odds ratio [OR] 0.018, 95% confidence interval [CI] 0.0019-0.17, P<0.001), dystocia where fetomaternal disproportion was present (OR 0.090, 95% CI 0.097-0.83, P=0.033), a female calf (OR 0.036, 95% CI 0.0019-0.69, P=0.027), no retained fetal membranes at the first post-operative revisit (OR 0.095, 95% CI 0.013-0.69, P=0.020) and removing abdominal blood clots during surgery (OR 0.10, 95% CI 0.011-0.93, P=0.043). Using a Utrecht suture pattern on the uterus was associated with reduced culling due to infertility (OR 0.12, 95% CI 0.020-0.67, P=0.016). Incision infection was noted in 25.9% of cases where incision status was recorded but this was not associated with the type of local anaesthesia used. Overall calf survival up to the first post-operative visit (24-48 h) was 59.4%, and was associated with shorter duration of surgery, and dystocia due to fetomaternal disproportion. These results offer some evidence-based guidelines to optimise outcomes for this common surgery performed under field conditions

Characterization of an Inherited Neurologic Syndrome in Toyger Cats with Forebrain Commissural Malformations, Ventriculomegaly and Interhemispheric Cysts.

BackgroundIn children, frequent congenital malformations with concomitant agenesis of the corpus callosum are diagnosed by neuroimaging in association with other cerebral malformations, including interhemispheric cysts and ventriculomegaly. Similar studies providing full characterization of brain defects by in vivo magnetic resonance imaging (MRI), and correlations with the pertinent anatomic pathologic examinations are absent in veterinary medicine.Hypothesis/objectivesCongenital brain defects underlie the neurologic signs observed in Toyger cats selectively bred for a short ear phenotype.AnimalsUsing proper pedigree analysis and genetic evaluations, 20 related Oriental-derived crossbred Toyger cats were evaluated. Seven clinically healthy (carrier) cats and 13 clinically affected cats that had neurologic signs, short ear phenotype and concomitant complex brain anomalies were studied.MethodsComplete physical and neurologic examinations and MRI were performed in all clinically healthy and affected cats. Postmortem and histopathologic examinations were performed in 8 affected cats and 5 healthy cats.ResultsNeurologic and MRI investigations confirmed 13 clinically affected cats with structural brain abnormalities. Ventriculomegaly with frequent concomitant supratentorial interhemispheric, communicating ventricular type-1b cysts and multiple midline and callosal malformations were detected in all cats displaying neurologic signs. Genetic analysis confirmed autosomal recessive mode of inheritance with no chromosomal abnormalities.Conclusions and clinical importanceNeuroanatomic dissections and histopathology were helpful for evaluation of abnormalities in midline brain structures, and for the full characterization of cysts. However, MRI was more sensitive for detection of small cysts. In this feline model, MRI diagnosis had extremely good correlation with pathologic abnormalities noted in the subset of animals that were examined by both modalities

Guidelines for the management of the foot health problems associated with rheumatoid arthritis

Background. Rheumatoid arthritis (RA) as a chronic systemic disease, commonly affects the feet, impacting negatively on patients' quality of life. Specialist podiatrists have a prime role to play in the assessment and management of foot and ankle problems within this patient group. However, it has been identified that in many areas there is no specialist podiatry service, with many patients being managed by non‐specialist podiatrists. Therefore, the North West Clinical Effectiveness Group for the Foot in Rheumatic Diseases (NWCEG) identified the need to develop ‘practitioner facing’ guidelines for the management of specific foot health problems associated with RA. Methods. Members of a guideline development group from the NWCEG each reviewed the evidence for specific aspects of the assessment and management of foot problems. Where evidence was lacking, ‘expert opinion’ was obtained from the members of the NWCEG and added as a consensus on current and best practice. An iterative approach was employed, with the results being reviewed and revised by all members of the group and external reviewers before the final guideline document was produced. Results. The management of specific foot problems (callus, nail pathology, ulceration) and the use of specific interventions (foot orthoses, footwear, patient education, steroid injection therapy) are detailed and standards in relation to each are provided. A diagrammatic screening pathway is presented, with the aim of guiding nonspecialist podiatrists through the complexity of assessing and managing those patients with problems requiring input from a specialist podiatrist and other members of the rheumatology multidisciplinary team. Conclusion. This pragmatic approach ensured that the guidelines were relevant and applicable to current practice as ‘best practice’, based on the available evidence from the literature and consensus expert opinion. These guidelines provide both specialist and non‐specialist podiatrists with the essential and ‘gold standard’ aspects of managing people with RA‐related foot problems

Volunteer tourism as alternative tourism: Journeys beyond otherness

Seismic changes in leisure time, disposable income, mobility and communication technologies have created a context in which tourism has thrived, grown and diversified to encompass a wide array of leisure travel behaviours that were not imagined even as recently as a couple of decades ago. Leading the way in this process of diversification is alternative tourism, which describes a form of tourism that rebukes mass tourism and the consumptive mindset it engenders and instead offers alternative, more discriminating, socially and environmentally sustaining tourist experiences (Wearing, 2001). The demand for alternative tourism has led to a diverse array of niche products and services, each the subject of critical scholarly analysis including educational tourism, farm tourism, cultural exchange tourism, scientific tourism and volunteer tourism, which is the subject and focus of this book. Definitions of volunteer tourism have begun to emerge in the academic and popular literature and are cited in a number of the case studies presented in this volume. Some of these definitions are relatively narrow in their focus. For example, Wearing (2002) defines volunteer tourists as those who 'volunteer in an organized way to undertake holidays that may involve the aiding or alleviating the material poverty of some groups in society, the restoration of certain environments, or research into aspects of society or environment' (p. 240). This definition uses criteria that limit volunteer tourism to those experiences located within the context of holidays or vacations. Others take a more macro-approach and consider the more inclusive notion of volunteering in tourism as an expression of what is recognized in tourism literature as the "other" dimension of postmodern tourism, which emphasizes the growing appeal of concepts such as "alternative", "real", "ecological", and "responsible" forms of tourism'. While specific definitions are used in some of the contributions to this book to frame individual case studies, we have resisted the temptation to offer an overarching definition of volunteer tourism for this volume. Instead we recognize volunteer tourism as a form of contested alternative tourism

Is the New Resonance Spin 0 or 2? Taking a Step Forward in the Higgs Boson Discovery

The observation of a new boson of mass \sim 125\gev at the CERN LHC may finally have revealed the existence of a Higgs boson. Now we have the opportunity to scrutinize its properties, determining its quantum numbers and couplings to the standard model particles, in order to confirm or not its discovery. We show that by the end of the 8 TeV run, combining the entire data sets of ATLAS and CMS, it will be possible to discriminate between the following discovery alternatives: a scalar $J^P=0^+$ or a tensor $J^P=2^+$ particle with minimal couplings to photons, at a $5\sigma$ statistical confidence level at least, using only diphotons events. Our results are based on the calculation of a center-edge asymmetry measure of the reconstructed {\it sPlot} scattering polar angle of the diphotons. The results based on asymmetries are shown to be rather robust against systematic uncertainties with comparable discrimination power to a log likelihood ratio statistic.Comment: 11 pages, 6 figures, 1 table. References added, minor typos correcte