'Working our way to health': Final Evaluation Report

This summary presents the findings of an independent evaluation of the ‘Working our Way to Health’ programme. This programme was delivered by Sefton PCT, funded through the Neighbourhood Renewal Fund, and was aimed at improving the health of men in three of the most deprived wards in its locality. It aimed to encourage men to be health aware and increase access to health and leisure services in order to improve key lifestyle behaviours and advance gender equity. The programme included: • Community agency and health staff training • Peer mentoring programme • Healthy lifestyle programme It aimed to promote community partnerships to assist the expansion of health advice and services into a new community arena and engage a previously unattainable section of the male population in healthier lifestyle interventions

"Talk" about male suicide? Learning from community programmes

Purpose – The purpose of this paper is to examine the contribution of public awareness campaigning in developing community capacity toward preventing male suicide and explores emerging considerations for suicide prevention programme development. Design/methodology/approach – The paper draws on campaign evaluation data, specifically qualitative discussion groups with the general public, to report results concerning campaign processes, and “interim” effectiveness in changing public awareness and attitudes, and then discusses how progress is to be lasting and transformational. Findings – The campaign raised the awareness of a substantial proportion of those targeted, and affected attitudes and behaviour of those who were highly aware. The community settings approach was effective in reaching younger men, but there were challenges targeting the public more selectively, and engaging communities in a sustained way. Practical implications – The paper discusses emerging considerations for suicide prevention, focusing on gender and approaches and materials for engaging with the public as “influencers”. There are challenges to target audiences more specifically, provide a clear call to action, and engage the public in a sustained way. Social implications – The paper discusses emerging considerations for suicide prevention, focusing on gender and approaches and materials for engaging with the public as “influencers”. There are challenges to target audiences more specifically, provide a clear call to action, and engage the public in a sustained way. Originality/value – The paper adds fresh evidence of gendered communication processes, including their effects on public awareness, attitudes and engagement. Application of a theory of change model leads to systems level findings for sustaining programme gains

Research study on materials processing in space experiment M512

A study program was conducted to clarify the role of gravity in the fluid mechanics of certain molten metal processes of potential significance to manufacturing in space. In particular, analyses were conducted of the M551 Metals Melting Experiment and the M553 Sphere Forming Experiment to be conducted in the M512 Facility onboard Skylab. The M551 experiment consisted of a study of electron beam welding of various metals, and the M553 experiment studied the formation of molten metal spheres by free-floating in a near zero-gravity environment. The analyses of these experiments and a comparison with ground-based and KC135 experimental results are presented

Evaluation of the Choose Life North Lanarkshire Awareness Programme: Final Report

The Centre for Men’s Health at Leeds Metropolitan University, with consultants from MRC Social and Public Health Sciences Unit, Glasgow, and Men’s Health Forum, Scotland (MHFS), were appointed to conduct the Choose Life (North Lanarkshire) evaluation, beginning in March 2011. The key evaluation questions are: 1. How has the social marketing approach to increase awareness of crisis service numbers and de-stigmatise understandings and attitudes about suicide worked? 2. Has the programme as implemented been effective? Which aspects of the programme have been particularly effective? 3. Has this programme been of benefit to the community, in particular young men aged 16-35? 4. What contribution has the community made to the effectiveness of the programme

Influencing public awareness to prevent male suicide

Purpose – The purpose of this paper is to report findings from a formative evaluation of a suicide prevention public awareness campaign – Choose Life, North Lanarkshire. The focus is on preventing male suicide. The paper explores how the public campaign supports a co-ordinated and community-based direction for suicide prevention work, and examines how good practice can be identified, spread, and sustained. Design/methodology/approach – The paper draws on data collected from March to November 2011, using mixed primary research methods, including a quota survey, discussion groups with the general public, and stakeholder interviews. Findings – The campaign effectively raised the suicide awareness of a substantial proportion of those targeted, but with regional variations. It also affected the attitudes and behaviour of those who were highly aware. However, men and women engaged somewhat differently with the campaign. The sports and leisure settings approach was effective in reaching younger men. Practical implications – The paper discusses emerging considerations for suicide prevention, focusing on gender and approaches and materials for engaging with the public as “influencers”. There are challenges to target audiences more specifically, provide a clear call to action, and engage the public in a sustained way. Originality/value – This paper reflects on insights from a complex programme, exceptional in its focus on targeted sections of the public, especially young males. The paper indicates the importance for research and practice of intersecting dimensions of male identity, stigma and mental health, and other risk and protective factors which can inform campaigns highlighting talk about suicide among men

Research summary

The final report for progress during the period from 15 Nov. 1988 to 14 Nov. 1991 is presented. Research on methods for analysis of sound propagation through the atmosphere and on results obtained from application of our methods are summarized. Ten written documents of NASA research are listed, and these include publications, manuscripts accepted, submitted, or in preparation for publication, and reports. Twelve presentations of results, either at scientific conferences or at research or technical organizations, since the start of the grant period are indicated. Names of organizations to which software produced under the grant was distributed are provided, and the current arrangement whereby the software is being distributed to the scientific community is also described. Finally, the names of seven graduate students who worked on NASA research and received Rensselaer degrees during the grant period, along with their current employers are given

Adaptive HIV-1 evolutionary trajectories are constrained by protein stability

Despite the use of combination antiretroviral drugs for the treatment of HIV-1 infection, the emergence of drug resistance remains a problem. Resistance may be conferred either by a single mutation or a concerted set of mutations. The involvement of multiple mutations can arise due to interactions between sites in the amino acid sequence as a consequence of the need to maintain protein structure. To better understand the nature of such epistatic interactions, we reconstructed the ancestral sequences of HIV-1's Pol protein, and traced the evolutionary trajectories leading to mutations associated with drug resistance. Using contemporary and ancestral sequences we modelled the effects of mutations (i.e. amino acid replacements) on protein structure to understand the functional effects of residue changes. Although the majority of resistance-associated sequences tend to destabilise the protein structure, we find there is a general tendency for protein stability to decrease across HIV-1's evolutionary history. That a similar pattern is observed in the non-drug resistance lineages indicates that non-resistant mutations, for example, associated with escape from the immune response, also impacts on protein stability. Maintenance of optimal protein structure therefore represents a major constraining factor to the evolution of HIV-1

Probing Velocity Dependent Self-Interacting Dark Matter with Neutrino Telescopes

Self-interacting dark matter models constitute an attractive solution to problems in structure formation on small scales. A simple realization of these models considers the dark force mediated by a light particle which can couple to the Standard Model through mixings with the photon or the $Z$ boson. Within this scenario we investigate the sensitivity of the IceCube-DeepCore and PINGU neutrino telescopes to the associated muon neutrino flux produced by dark matter annihilations in the Sun. Despite the model's simplicity, several effects naturally appear: momentum suppressed capture by nuclei, velocity dependent dark matter self-capture, Sommerfeld enhanced annihilation, as well as the enhancement on the neutrino flux due to mediator late decays. Taking all these effects into account, we find that most of the model relevant parameter space can be tested by the three years of data already collected by the IceCube-DeepCore. We show that indirect detection through neutrinos can compete with the strong existing limits from direct detection experiments, specially in the case of isospin violation.Comment: 7 figures, Published versio