919 research outputs found
Super-lattice, rhombus, square, and hexagonal standing waves in magnetically driven ferrofluid surface
Standing wave patterns that arise on the surface of ferrofluids by (single
frequency) parametric forcing with an ac magnetic field are investigated
experimentally. Depending on the frequency and amplitude of the forcing, the
system exhibits various patterns including a superlattice and subharmonic
rhombuses as well as conventional harmonic hexagons and subharmonic squares.
The superlattice arises in a bicritical situation where harmonic and
subharmonic modes collide. The rhombic pattern arises due to the non-monotonic
dispersion relation of a ferrofluid
Logics of Finite Hankel Rank
We discuss the Feferman-Vaught Theorem in the setting of abstract model
theory for finite structures. We look at sum-like and product-like binary
operations on finite structures and their Hankel matrices. We show the
connection between Hankel matrices and the Feferman-Vaught Theorem. The largest
logic known to satisfy a Feferman-Vaught Theorem for product-like operations is
CFOL, first order logic with modular counting quantifiers. For sum-like
operations it is CMSOL, the corresponding monadic second order logic. We
discuss whether there are maximal logics satisfying Feferman-Vaught Theorems
for finite structures.Comment: Appeared in YuriFest 2015, held in honor of Yuri Gurevich's 75th
birthday. The final publication is available at Springer via
http://dx.doi.org/10.1007/978-3-319-23534-9_1
Wave Number of Maximal Growth in Viscous Magnetic Fluids of Arbitrary Depth
An analytical method within the frame of linear stability theory is presented
for the normal field instability in magnetic fluids. It allows to calculate the
maximal growth rate and the corresponding wave number for any combination of
thickness and viscosity of the fluid. Applying this method to magnetic fluids
of finite depth, these results are quantitatively compared to the wave number
of the transient pattern observed experimentally after a jump--like increase of
the field. The wave number grows linearly with increasing induction where the
theoretical and the experimental data agree well. Thereby a long-standing
controversy about the behaviour of the wave number above the critical magnetic
field is tackled.Comment: 19 pages, 15 figures, RevTex; revised version with a new figure and
references added. submitted to Phys Rev
Critical exponents of directed percolation measured in spatiotemporal intermittency
A new experimental system showing a transition to spatiotemporal
intermittency is presented. It consists of a ring of hundred oscillating
ferrofluidic spikes. Four of five of the measured critical exponents of the
system agree with those obtained from a theoretical model of directed
percolation.Comment: 7 pages, 12 figures, submitted to PR
Take their word for it: The symbolic role of linguistic style matches in user communities
User communities are increasingly becoming an essential element of companies' business processes. However, reaping the benefits of such social systems does not always prove effective, often because companies fail to stimulate members' collaboration continuously or neglect their social integration. Following communication accommodation theory, the authors posit that members' communication style alignment symbolically reflects their community identification and affects subsequent participation behavior. This research uses text mining to extract the linguistic style properties of 74,246 members' posts across 37 user communities. Two mixed multilevel Poisson regression models show that when members' linguistic style matches with the conventional community style, it signals their community identification and affects their participation quantity and quality. Drawing on an expanded view of organizational identification, the authors consider dynamics in members' social identification by examining trends and reversals in linguistic style match developments. Whereas a stronger trend of alignment leads to greater participation quantity and quality, frequent reversals suggest lower participation quantity. At a community level, greater synchronicity in the linguistic style across all community members fosters individual members' participation behavior
Retrograde semaphorin-plexin signalling drives homeostatic synaptic plasticity.
Homeostatic signalling systems ensure stable but flexible neural activity and animal behaviour. Presynaptic homeostatic plasticity is a conserved form of neuronal homeostatic signalling that is observed in organisms ranging from Drosophila to human. Defining the underlying molecular mechanisms of neuronal homeostatic signalling will be essential in order to establish clear connections to the causes and progression of neurological disease. During neural development, semaphorin-plexin signalling instructs axon guidance and neuronal morphogenesis. However, semaphorins and plexins are also expressed in the adult brain. Here we show that semaphorin 2b (Sema2b) is a target-derived signal that acts upon presynaptic plexin B (PlexB) receptors to mediate the retrograde, homeostatic control of presynaptic neurotransmitter release at the neuromuscular junction in Drosophila. Further, we show that Sema2b-PlexB signalling regulates presynaptic homeostatic plasticity through the cytoplasmic protein Mical and the oxoreductase-dependent control of presynaptic actin. We propose that semaphorin-plexin signalling is an essential platform for the stabilization of synaptic transmission throughout the developing and mature nervous system. These findings may be relevant to the aetiology and treatment of diverse neurological and psychiatric diseases that are characterized by altered or inappropriate neural function and behaviour
Social Interactions vs Revisions, What is important for Promotion in Wikipedia?
In epistemic community, people are said to be selected on their knowledge
contribution to the project (articles, codes, etc.) However, the socialization
process is an important factor for inclusion, sustainability as a contributor,
and promotion. Finally, what does matter to be promoted? being a good
contributor? being a good animator? knowing the boss? We explore this question
looking at the process of election for administrator in the English Wikipedia
community. We modeled the candidates according to their revisions and/or social
attributes. These attributes are used to construct a predictive model of
promotion success, based on the candidates's past behavior, computed thanks to
a random forest algorithm.
Our model combining knowledge contribution variables and social networking
variables successfully explain 78% of the results which is better than the
former models. It also helps to refine the criterion for election. If the
number of knowledge contributions is the most important element, social
interactions come close second to explain the election. But being connected
with the future peers (the admins) can make the difference between success and
failure, making this epistemic community a very social community too
Characterisation of a 3-hydroxypropionic acid-inducible system from Pseudomonas putida for orthogonal gene expression control in Escherichia coli and Cupriavidus necator
3-hydroxypropionic acid (3-HP) is an important platform chemical used as a precursor for production of added-value compounds such as acrylic acid. Metabolically engineered yeast, Escherichia coli, cyanobacteria and other microorganisms have been developed for the biosynthesis of 3-HP. Attempts to overproduce this compound in recombinant Pseudomonas denitrificans revealed that 3-HP is consumed by this microorganism using the catabolic enzymes encoded by genes hpdH, hbdH and mmsA. 3-HP-inducible systems controlling the expression of these genes have been predicted in proteobacteria and actinobacteria. In this study, we identify and characterise 3-HP-inducible promoters and their corresponding LysR-type transcriptional regulators from Pseudomonas putida KT2440. A newly-developed modular reporter system proved possible to demonstrate that PpMmsR/PmmsA and PpHpdR/PhpdH are orthogonal and highly inducible by 3-HP in E. coli (12.3- and 23.3-fold, respectively) and Cupriavidus necator (51.5- and 516.6-fold, respectively). Bioinformatics and mutagenesis analyses revealed a conserved 40-nucleotide sequence in the hpdH promoter, which plays a key role in HpdR-mediated transcription activation. We investigate the kinetics and dynamics of the PpHpdR/PhpdH switchable system in response to 3-HP and show that it is also induced by both enantiomers of 3-hydroxybutyrate. These findings pave the way for use of the 3-HP-inducible system in synthetic biology and biotechnology applications
Probing structure and dynamics in poly[2,2 '-(m-phenylene)-5,5 '-bibenzimidazole] fuel cells with magic-angle spinning NMR
Live attenuated influenza viruses produced in a suspension process with avian AGE1.CR.pIX cells
Background: Current influenza vaccines are trivalent or quadrivalent inactivated split or subunit vaccines administered intramuscularly, or live attenuated influenza vaccines (LAIV) adapted to replicate at temperatures below body temperature and administered intranasally. Both vaccines are considered safe and efficient, but due to differences in specific properties may complement each other to ensure reliable vaccine coverage. By now, licensed LAIV are produced in embryonated chicken eggs. In the near future influenza vaccines for human use will also be available from adherent MDCK or Vero cell cultures, but a scalable suspension process may facilitate production and supply with vaccines. Results: We evaluated the production of cold-adapted human influenza virus strains in the duck suspension cell line AGE1.CR.pIX using a chemically-defined medium. One cold-adapted A (H1N1) and one cold-adapted B virus strain was tested, as well as the reference strain A/PR/8/34 (H1N1). It is shown that a medium exchange is not required for infection and that maximum virus titers are obtained for 1x10-6 trypsin units per cell. 1 L bioreactor cultivations showed that 4x106 cells/mL can be infected without a cell density effect achieving titers of 1x108 virions/mL after 24 h. Conclusions: Overall, this study demonstrates that AGE1.CR.pIX cells support replication of LAIV strains in a chemically-defined medium using a simple process without medium exchanges. Moreover, the process is fast with peak titers obtained 24 h post infection and easily scalable to industrial volumes as neither microcarriers nor medium replacements are required. © 2012 Lohr et al.; licensee BioMed Central Ltd. [accessed 2013 November 18th
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