Ivermectin in the treatment of Bancroftian filariasis infection in Orissa, India

Ivermectin treatment has evaluated for its efficacy and side reactions in sixty patients of Orissa with Bancroftian filarial infection and microfilaremia. Ivermectin was administered as a single oral dose at four dosage levels (20, 50. 100 and 200 μg/kg), and both microfilarial clearance and associated side reactions were monitored in a double blind fashion. Blood microfilariae were cleared in all patients at all dosages within 1 to 14 days. In most patients microfilariae reappeared by third month. The microfilaria appearance by third and sixth month averaged 12.2 to 44 percent of pretreatment values in the fourstudy groups. Side reactions were encountered in almost all patients, the commonest being fever. headache, weakness, myalgia and cough which occured most prominently 12 to 72 hours after treatment. Side reactions were more frequent and severe in patients with high microfilaria counts. Clinical reaction scores for each group were independent of the dose administered. The 200 μg dose group showed significantly more rapid microfilariae clearance and its delayed reappearance as compared with the other dosage groups and without inducing significantly greater clinical reaction scores

Efektivitas Penerapan Model Pembelajaran Student Fasilitator And Explaining Menggunakan Media Concept Map terhadap Peningkatan Pemahaman Konsep

Penelitian ini bertujuan (1) Untuk mengetahui gambaran peningkatan pemahaman konsep siswa kelasX SMA Negeri 1 Walenrang yang diajar menggunakan model pembelajaran Student Fasilitator andExplaining (2) Untuk mengetahui gambaran peningkatan pemahaman konsep siswa kelas X SMANegeri 1 Walenrang yang diajar tanpa menggunakan model student fasilitator and explaining (3)Untuk mengetahui model pembelajaran Student Fasilitator and Explaining efektif untukmeningkatkan pemahaman konsep fisika siswa dari pada siswa yang tidak diajar dengan modelpembelajaran Student Fasilitator and Explaining kelas X SMA Negeri 1 Walenrang. Penelitian inimerupakan jenis penelitian Quasi Experimental Design dengan menggunakan desain penelitian pretestposttestcontrol group design. Teknik analisis yang digunakan adalah analisis statistik deskriptif dananalisis statistik inferensial. Berdasarkan hasil analisis statistik inferensial diperoleh Dhitung = 0,56 , dapat disimpulkan bahwapenerapan Model pembelajaran Student Fasilitator and Explaining dengan Menggunakan MediaConcept Map efektif untuk meningkatkan pemahaman konsep fisika siswa daripada siswa yang tidakdiajar dengan model pembelajaran Student Fasilitator and Explaining dengan Menggunakan MediaConcept Siswa Kelas X SMAN 1 Walenran

Cognitive transfer of spatial awareness states from immersive virtual environments to reality.

An individual's prior experience will influence how new visual information in a scene is perceived and remembered. Accuracy of memory performance per se is an imperfect reflection of the cognitive activity (awareness states) that underlies performance in memory tasks. The aim of this research is to investigate the effect of varied visual fidelity of training environments on the transfer of training to the real-world after exposure to immersive simulations representing a real-world scene. A between groups experiment was carried out to explore the effect of rendering quality on measurements of location-based recognition memory for objects and associated states of awareness. The immersive simulation, consisted of one room that was either rendered flat-shaded or using radiosity rendering. The simulation was displayed on a stereo head-tracked Head Mounted Display. Post exposure to the synthetic simulation, participants completed a memory recognition task conducted in a real-world scene by physically arranging objects in their physical form in a real world room. Participants also reported one of four states of awareness following object recognition. They were given several options of awareness states that reflected the level of visual mental imagery involved during retrieval, the familiarity of the recollection and related guesses. The scene incorporated objects that 'fitted' into the specific context of the real-world scene, referred to as consistent objects, and objects which were not related to the specific context of the real-world scene, referred to as inconsistent objects. A follow-up study was conducted a week after the initial test. Interestingly, results revealed a higher proportion of correct object recognition associated with mental imagery when participants were exposed to low fidelity flat-shaded training scenes rather than the radiosity rendered ones. Memory psychology indicates that awareness states based on visual imagery require stronger attentional processing in the first instance than those based on familiarity. A tentative claim would therefore be that those immersive environments that are distinctive because of their variation from 'real', such as flat-shaded environments, recruit stronger attentional resources. This additional attentional processing may bring about a change in participants' subjective experiences of 'remembering' when they later transfer the training from that environment into a real-world situation

On the monotone stability approach to BSDEs with jumps: Extensions, concrete criteria and examples

We show a concise extension of the monotone stability approach to backward stochastic differential equations (BSDEs) that are jointly driven by a Brownian motion and a random measure for jumps, which could be of infinite activity with a non-deterministic and time inhomogeneous compensator. The BSDE generator function can be non convex and needs not to satisfy global Lipschitz conditions in the jump integrand. We contribute concrete criteria, that are easy to verify, for results on existence and uniqueness of bounded solutions to BSDEs with jumps, and on comparison and a-priori $L^{\infty}$-bounds. Several examples and counter examples are discussed to shed light on the scope and applicability of different assumptions, and we provide an overview of major applications in finance and optimal control.Comment: 28 pages. Added DOI https://link.springer.com/chapter/10.1007%2F978-3-030-22285-7_1 for final publication, corrected typo (missing gamma) in example 4.1

A Delayed Black and Scholes Formula I

In this article we develop an explicit formula for pricing European options when the underlying stock price follows a non-linear stochastic differential delay equation (sdde). We believe that the proposed model is sufficiently flexible to fit real market data, and is yet simple enough to allow for a closed-form representation of the option price. Furthermore, the model maintains the no-arbitrage property and the completeness of the market. The derivation of the option-pricing formula is based on an equivalent martingale measure

Nickel induced exposure analysis for toxic changes in growth and antioxidative enzymes in sesban eliciting biochemical sensitivity

Nickel (Ni) exposure in plants leads to severe toxicity problems, with effects varying depending on its exposure concentration. The present pot culture investigation assesses the phytotoxic effects of different Nickel (Ni) concentrations on various biochemical parameters of Sesbania. The study involves applying Nickel at 50, 100, 200, and 300 ppm along with a control group at 0 ppm for 30 days. Results revealed retarded growth, reduced pigment content, and enhanced antioxidative enzyme activity as nickel concentration increased. Exposure to Ni (100 ppm) and above severely affects seed germination, plant growth, and biomass production. Furthermore, relative phytotoxicity was evident from a 15% reduced germination rate and a fall in germination index from 10 to 8.5. The seedling vigour index was drastically reduced from 960 (control) to 93.5(300 ppm Ni). In addition to these, plant growth retardation was striking with root length stunted by 70% and shoot length by 50% in response to Ni (300 ppm). Chlorophyll and carotenoid contents decreased by nearly 50% with the 300-ppm nickel treatment. Although protein levels and antioxidant enzyme activity (catalase and peroxidase) showed a stimulatory response to 100 and 200 ppm Ni treatments, both suffered a sharp decline due to toxic stress at 300 ppm Ni. This study explicitly highlights the harmful effects of high doses of Ni, highlighting the sensitivity of various morphometric and biochemical parameters to Ni toxicity. These findings highlights the need to mitigate environmental contamination and adopt measures to protect plant health

Precise 3D track reconstruction algorithm for the ICARUS T600 liquid argon time projection chamber detector

Liquid Argon Time Projection Chamber (LAr TPC) detectors offer charged particle imaging capability with remarkable spatial resolution. Precise event reconstruction procedures are critical in order to fully exploit the potential of this technology. In this paper we present a new, general approach of three-dimensional reconstruction for the LAr TPC with a practical application to track reconstruction. The efficiency of the method is evaluated on a sample of simulated tracks. We present also the application of the method to the analysis of real data tracks collected during the ICARUS T600 detector operation with the CNGS neutrino beam.Comment: Submitted to Advances in High Energy Physic

Quadratic BSDEs driven by a continuous martingale and application to utility maximization problem

In this paper, we study a class of quadratic Backward Stochastic Differential Equations (BSDEs) which arises naturally when studying the problem of utility maximization with portfolio constraints. We first establish existence and uniqueness results for such BSDEs and then, we give an application to the utility maximization problem. Three cases of utility functions will be discussed: the exponential, power and logarithmic ones

Bivalent nickel exposure induced mitotic toxicity in onion root tips

Nickel (Ni) is utilized across multiple industries, resulting in significant environmental contamination and exhibiting various genotoxic effects on plants and animals due to its release into the external environment. This study evaluates the cytotoxic effects of different doses of nickel on onion (Allium cepa L.) root tips. To evaluate the sensitivity of Nickel, bulbs of onion were treated at 10, 25, 50 and 100 ppm along with a control (0 ppm) using NiCl2 salt as the source of Nickel. At elevated concentrations of nickel (100 ppm) in a hydroponic study, the onion roots exhibited browning and translucency, accompanied by a retardation of growth. Various chromosomal anomalies, including chromosomal breaks, laggards, vagrant chromosomes, bridges, distorted chromosomes, sticky chromosomes, c-mitosis etc. were observed following a 24 hr exposure to toxic doses of nickel. Both types of chromosomal abnormalities, namely spindle fibre abnormality (SFA) and chromosomal abnormality (CA), were observed under Ni treatment. The evaluation of cell death in the treated roots was done using the Evans blue dye test. Uptake of Evans blue by the root cells demonstrated the cell death parameter, which served as an indicator of cytotoxicity

Search for anomalies in the {\nu}e appearance from a {\nu}{\mu} beam

We report an updated result from the ICARUS experiment on the search for {\nu}{\mu} ->{\nu}e anomalies with the CNGS beam, produced at CERN with an average energy of 20 GeV and travelling 730 km to the Gran Sasso Laboratory. The present analysis is based on a total sample of 1995 events of CNGS neutrino interactions, which corresponds to an almost doubled sample with respect to the previously published result. Four clear {\nu}e events have been visually identified over the full sample, compared with an expectation of 6.4 +- 0.9 events from conventional sources. The result is compatible with the absence of additional anomalous contributions. At 90% and 99% confidence levels the limits to possible oscillated events are 3.7 and 8.3 respectively. The corresponding limit to oscillation probability becomes consequently 3.4 x 10-3 and 7.6 x 10-3 respectively. The present result confirms, with an improved sensitivity, the early result already published by the ICARUS collaboration