Analytical method for parameterizing the random profile components of nanosurfaces imaged by atomic force microscopy

The functional properties of many technological surfaces in biotechnology, electronics, and mechanical engineering depend to a large degree on the individual features of their nanoscale surface texture, which in turn are a function of the surface manufacturing process. Among these features, the surface irregularities and self-similarity structures at different spatial scales, especially in the range of 1 to 100 nm, are of high importance because they greatly affect the surface interaction forces acting at a nanoscale distance. An analytical method for parameterizing the surface irregularities and their correlations in nanosurfaces imaged by atomic force microscopy (AFM) is proposed. In this method, flicker noise spectroscopy - a statistical physics approach - is used to develop six nanometrological parameters characterizing the high-frequency contributions of jump- and spike-like irregularities into the surface texture. These contributions reflect the stochastic processes of anomalous diffusion and inertial effects, respectively, in the process of surface manufacturing. The AFM images of the texture of corrosion-resistant magnetite coatings formed on low-carbon steel in hot nitrate solutions with coating growth promoters at different temperatures are analyzed. It is shown that the parameters characterizing surface spikiness are able to quantify the effect of process temperature on the corrosion resistance of the coatings. It is suggested that these parameters can be used for predicting and characterizing the corrosion-resistant properties of magnetite coatings.Comment: 7 pages, 3 figures, 2 tables; to be published in Analys

BLiSS: Bootstrapped Linear Shape Space

Morphable models are fundamental to numerous human-centered processes as they offer a simple yet expressive shape space. Creating such morphable models, however, is both tedious and expensive. The main challenge is establishing dense correspondences across raw scans that capture sufficient shape variation. This is often addressed using a mix of significant manual intervention and nonrigid registration. We observe that creating a shape space and solving for dense correspondence are tightly coupled - while dense correspondence is needed to build shape spaces, an expressive shape space provides a reduced dimensional space to regularize the search. We introduce BLiSS, a method to solve both progressively. Starting from a small set of manually registered scans to bootstrap the process, we enrich the shape space and then use that to get new unregistered scans into correspondence automatically. The critical component of BLiSS is a non-linear deformation model that captures details missed by the low-dimensional shape space, thus allowing progressive enrichment of the space

Gesture's body orientation modulates the N400 for visual sentences primed by gestures

Body orientation of gesture entails social‐communicative intention, and may thus influence how gestures are perceived and comprehended together with auditory speech during face‐to‐face communication. To date, despite the emergence of neuroscientific literature on the role of body orientation on hand action perception, limited studies have directly investigated the role of body orientation in the interaction between gesture and language. To address this research question, we carried out an electroencephalography (EEG) experiment presenting to participants (n = 21) videos of frontal and lateral communicative hand gestures of 5 s (e.g., raising a hand), followed by visually presented sentences that are either congruent or incongruent with the gesture (e.g., “the mountain is high/low…”). Participants underwent a semantic probe task, judging whether a target word is related or unrelated to the gesture‐sentence event. EEG results suggest that, during the perception phase of handgestures, while both frontal and lateral gestures elicited a power decrease in both the alpha (8–12 Hz) and the beta (16–24 Hz) bands, lateral versus frontal gestures elicited reduced power decrease in the beta band, source‐located to the medial prefrontal cortex. For sentence comprehension, at the critical word whose meaning is congruent/incongruent with the gesture prime, frontal gestures elicited an N400 effect for gesture‐sentence incongruency. More importantly, this incongruency effect was significantly reduced for lateral gestures. These findings suggest that body orientation plays an important role in gesture perception, and that its inferred social‐communicative intention may influence gesture‐language interaction at semantic level

GLASS: Geometric Latent Augmentation for Shape Spaces

We investigate the problem of training generative models on very sparse collections of 3D models. Particularly, instead of using difficult-to-obtain large sets of 3D models, we demonstrate that geometrically-motivated energy functions can be used to effectively augment and boost only a sparse collection of example (training) models. Technically, we analyze the Hessian of the as-rigid-as-possible (ARAP) energy to adaptively sample from and project to the underlying (local) shape space, and use the augmented dataset to train a variational autoencoder (VAE). We iterate the process, of building latent spaces of VAE and augmenting the associated dataset, to progressively reveal a richer and more expressive generative space for creating geometrically and semantically valid samples. We evaluate our method against a set of strong baselines, provide ablation studies, and demonstrate application towards establishing shape correspondences. Glassproduces multiple interesting and meaningful shape variations even when starting from as few as 3-10 training shapes. Our code is available at https://sanjeevmk.github.io/glass_webpage/

Attitude of Solo Librarians in Promoting Sustainability in India: Challenges and Opportunities        

This study explores solo librarians' perceptions of their role in sustainability and assesses their opinions, familiarity, and interest concerning the topic. It also examines their attitudes toward promoting the Sustainable Development Goals (SDGs) and evaluates professional perspectives on the level of management support for such initiatives, identifying factors that influence engagement and collaboration. Data was gathered from 180 solo librarians across Kerala, Tamil Nadu, and Karnataka. The findings show librarians recognize their crucial function in advancing sustainability through inclusivity, lifelong learning, and open access. Those with higher qualifications and experience were significantly more active. While most solo librarians do promote sustainability activities, the research highlights a pressing need: varied management support and reliance on non-professional staff undercut their efforts. However, varied support from management and frequent reliance on non-professional staff highlight the need for greater institutional support and formal recognition to encourage librarians to undertake sustainability-related initiatives. &nbsp

Grain boundary migration in polycrystalline α\alpha-Fe

High energy x-ray diffraction microscopy was used to image the microstructure of $\alpha$-Fe before and after a 600 $^\circ$C anneal. These data were used to determine the areas, curvatures, energies, and velocities of approximately 40,000 grain boundaries. The measured grain boundary properties depend on the five macroscopic grain boundary parameters. The velocities are not correlated with the product of the mean boundary curvature and grain boundary energy, usually assumed to be the driving force. Boundary migration is made up of area changes (lateral motion) and translation (normal motion) and both contribute to the total migration. Through the lateral motion component of the migration, low energy boundaries tend to expand in area while high energy boundaries shrink, reducing the average energy through grain boundary replacement. The driving force for this process is not related to curvature and might disrupt the expected curvature-velocity relationship.Comment: 33 pages, double spaced, accepted for publication in Acta Materiali

Withania somnifera Root Extract Enhances Chemotherapy through ‘Priming’

Withania somnifera extracts are known for their anti-cancerous, anti-inflammatory and antioxidative properties. One of their mechanisms of actions is to modulate mitochondrial function through increasing oxidative stress. Recently ‘priming’ has been suggested as a potential mechanism for enhancing cancer cell death. In this study we demonstrate that ‘priming’, in HT-29 colon cells, with W. somnifera root extract increased the potency of the chemotherapeutic agent cisplatin. We have also showed the W. somnifera root extract enhanced mitochondrial dysfunction and that the underlying mechanism of ‘priming’ was selectively through increased ROS. Moreover, we showed that this effect was not seen in non-cancerous cells

Variation in the provision and practice of implant-based breast reconstruction in the UK: Results from the iBRA national practice questionnaire

Introduction: The introduction of biological and synthetic meshes has revolutionised the practice of implant-based breast reconstruction (IBBR) but evidence for effectiveness is lacking. The iBRA (implant Breast Reconstruction evAluation) study is a national trainee-led project that aims to explore the practice and outcomes of IBBR to inform the design of a future trial. We report the results of the iBRA National Practice Questionnaire (NPQ) which aimed to comprehensively describe the provision and practice of IBBR across the UK. Methods: A questionnaire investigating local practice and service provision of IBBR developed by the iBRA Steering Group was completed by trainee and consultant leads at breast and plastic surgical units across the UK. Summary data for each survey item were calculated and variation between centres and overall provision of care examined. Results: 81 units within 79 NHS-hospitals completed the questionnaire. Units offered a range of reconstructive techniques, with IBBR accounting for 70% (IQR:50–80%) of participating units' immediate procedures. Units on average were staffed by 2.5 breast surgeons (IQR:2.0–3.0) and 2.0 plastic surgeons (IQR:1.0–3.0) performing 35 IBBR cases per year (IQR:20-50). Variation was demonstrated in the provision of novel different techniques for IBBR especially the use of biological (n = 62) and synthetic (n = 25) meshes and in patient selection for these procedures. Conclusions: The iBRA-NPQ has demonstrated marked variation in the provision and practice of IBBR in the UK. The prospective audit phase of the iBRA study will determine the safety and effectiveness of different approaches to IBBR and allow evidence-based best practice to be explored