Interpretation at the controller's edge: designing graphical user interfaces for the digital publication of the excavations at Gabii (Italy)

This paper discusses the authors’ approach to designing an interface for the Gabii Project’s digital volumes that attempts to fuse elements of traditional synthetic publications and site reports with rich digital datasets. Archaeology, and classical archaeology in particular, has long engaged with questions of the formation and lived experience of towns and cities. Such studies might draw on evidence of local topography, the arrangement of the built environment, and the placement of architectural details, monuments and inscriptions (e.g. Johnson and Millett 2012). Fundamental to the continued development of these studies is the growing body of evidence emerging from new excavations. Digital techniques for recording evidence “on the ground,” notably SFM (structure from motion aka close range photogrammetry) for the creation of detailed 3D models and for scene-level modeling in 3D have advanced rapidly in recent years. These parallel developments have opened the door for approaches to the study of the creation and experience of urban space driven by a combination of scene-level reconstruction models (van Roode et al. 2012, Paliou et al. 2011, Paliou 2013) explicitly combined with detailed SFM or scanning based 3D models representing stratigraphic evidence. It is essential to understand the subtle but crucial impact of the design of the user interface on the interpretation of these models. In this paper we focus on the impact of design choices for the user interface, and make connections between design choices and the broader discourse in archaeological theory surrounding the practice of the creation and consumption of archaeological knowledge. As a case in point we take the prototype interface being developed within the Gabii Project for the publication of the Tincu House. In discussing our own evolving practices in engagement with the archaeological record created at Gabii, we highlight some of the challenges of undertaking theoretically-situated user interface design, and their implications for the publication and study of archaeological materials

Differences of interface and bulk transport properties in polymer field-effect devices

The influence of substrate treatment with self-assembled monolayers and thermal annealing was analysed by electrical and structural measurements on field-effect transistors (FETs) and metal-insulator-semiconductor (MIS) diodes using poly(3-hexylthiophene) (P3HT) as a semiconducting polymer and Si/SiO2 wafers as a substrate. It is found that surface treatment using silanising agents like hexamethyldisilazane (HMDS) and octadecyltrichlorosi-lane (OTS) can increase the field-effect mobility by up to a factor of 50, reaching values in saturation of more than 4E-2 cm^2/Vs at room temperature. While there is a clear correlation between the obtained field-effect mobility and the contact angle of water on the treated substrates, X-ray diffraction and capacitance measurements on MIS diodes show that structural and electrical properties in the bulk of the P3HT films are not influenced by the surface treatment. On the other hand, thermal annealing is found to cause an increase of grain size, bulk relaxation frequency and thereby of the mobility perpendicular to the SiO2/P3HT interface, but has very little influence on the field-effect mobility. Temperature dependent investigations on MIS diodes and FETs show that the transport perpendicular to the substrate plane is thermally activated and can be described by hopping in a Gaussian density of states, whereas the field-effect mobility in the substrate plane is almost temperature independent over a wide range. This investigations reveal significant differ-ences between interface and bulk transport properties in polymer field-effect devices.Comment: accepted at Organic electronic

The influence of distraction on speech processing: How selective is selective attention?

-* indicates shared first authorship - The present study investigated the effects of selective attention on the processing of morphosyntactic errors in unattended parts of speech. Two groups of German native (L1) speakers participated in the present study. Participants listened to sentences in which irregular verbs were manipulated in three different conditions (correct, incorrect but attested ablaut pattern, incorrect and crosslinguistically unattested ablaut pattern). In order to track fast dynamic neural reactions to the stimuli, electroencephalography was used. After each sentence, participants in Experiment 1 performed a semantic judgement task, which deliberately distracted the participants from the syntactic manipulations and directed their attention to the semantic content of the sentence. In Experiment 2, participants carried out a syntactic judgement task, which put their attention on the critical stimuli. The use of two different attentional tasks allowed for investigating the impact of selective attention on speech processing and whether morphosyntactic processing steps are performed automatically. In Experiment 2, the incorrect attested condition elicited a larger N400 component compared to the correct condition, whereas in Experiment 1 no differences between conditions were found. These results suggest that the processing of morphosyntactic violations in irregular verbs is not entirely automatic but seems to be strongly affected by selective attention

Nanofriction mechanisms derived from the dependence of friction on load and sliding velocity from air to UHV on hydrophilic silicon

This paper examines friction as a function of the sliding velocity and applied normal load from air to UHV in a scanning force microscope (SFM) experiment in which a sharp silicon tip slides against a flat Si(100) sample. Under ambient conditions, both surfaces are covered by a native oxide, which is hydrophilic. During pump-down in the vacuum chamber housing the SFM, the behavior of friction as a function of the applied normal load and the sliding velocity undergoes a change. By analyzing these changes it is possible to identify three distinct friction regimes with corresponding contact properties: (a) friction dominated by the additional normal forces induced by capillarity due to the presence of thick water films, (b) higher drag force from ordering effects present in thin water layers and (c) low friction due to direct solid-solid contact for the sample with the counterbody. Depending on environmental conditions and the applied normal load, all three mechanisms may be present at one time. Their individual contributions can be identified by investigating the dependence of friction on the applied normal load as well as on the sliding velocity in different pressure regimes, thus providing information about nanoscale friction mechanisms

High pCO 2 levels affect metabolic rate, but not feeding behavior and fitness, of farmed giant mussel Choromytilus chorus

Indexación: Scopus.Acknowledgements. We thank Luisa Saavedra and Araceli Rodriguez-Romero for their help in the field and during laboratory activities. We also acknowledge Laura Ramajo for help with AT estimations. Emily Giles Neill provided valuable comments that greatly improved the manuscript. Special thanks are due to the reviewers and the editor for very constructive comments on the manuscript. This study was supported by the Millennium Nucleus Center for the Study of Multiple drivers on Marine Socio-Ecological Systems (MUSELS) funded by MINECON NC120086, PIA CONICYT ACT-172037 and FONDECYT grant nos. 1140938 and 1140092 to N.A.L. and M.A.L.Mar Ecol Prog Ser 454: 65−74 Findlay HS, Wood HL, Kendall MA, Spicer JI, Twitchett RJ, Widdicombe S (2009) Calcification, a physiological pro-cess to be considered in the context of the whole organ-ism. Biogeosciences 6: 2267−2284 Fitzer SC, Zhu W, Tanner KE, Phoenix VR, Kamenos NA, Cusack M (2015) Ocean acidification alters the material properties of Mytilus edulis shells. J R Soc Interface 12: 214−227 Freitas R, De Marchi L, Bastos M, Moreira A and others (2017) Effects of seawater acidification and salinity alter-ations on metabolic, osmoregulation and oxidative stress markers in Mytilus galloprovincialis. Ecol Indic 79: 54−62 Gattuso JP, Magnan A, Billé R, Cheung WWL and others (2015) Contrasting futures for ocean and society from dif-ferent anthropogenic CO2 emissions scenarios. Science 349: aac4722 Gazeau F, Urbini L, Cox TE, Alliouane S, Gattuso JP (2015) Comparison of the alkalinity and calcium anomaly tech-niques to estimate rates of net calcification. Mar Ecol Prog Ser 527: 1−12 Gray MW, Langdon CJ, Waldbusser GG, Hales B, Kramer S (2017) Mechanistic understanding of ocean acidification impacts on larval feeding physiology and energy budg-ets of the mussel Mytilus californianus. Mar Ecol Prog Ser 563: 81−94 Griffiths CL, Griffiths RJ (1987) Animal energetics, Vol 2: Bivalvia through Reptilia. In: Pandian TJ, Vernberg FJ (eds) Bivalvia. Academic Press, New York, NY, p 1−88 Harvey BP, Dwynn-Jones D, Moore PJ (2013) Meta-analysis reveals complex marine biological responses to the inter-active effects of ocean acidification and warming. Ecol Evol 3: 1016−1030 Hiebenthal C, Philipp EER, Eisenhauer A, Wahl M (2013) Effects of seawater pCO2 and temperature on shell growth, shell stability, condition and cellular stress of western Baltic Sea Mytilus edulis (L.) and Arctica is - landica (L.). Mar Biol 160: 2073−2087 Ibarrola I, Arambalza U, Navarro JM, Urrutia MB, Navarro E (2012) Allometric relationships in feeding and diges-tion in the Chilean mytilids Mytilus chilensis (Hupé), Choromytilus chorus (Molina) and Aulacomya ater (Mo - lina): a comparative study. J Exp Mar Biol Ecol 426-427: 18−27 Lagos NA, Benítez S, Duarte C, Lardies MA and others (2016) Effects of temperature and ocean acidification on shell characteristics of Argopecten purpuratus: implica-tions for scallop aquaculture in an upwelling-influenced area. Aquacult Environ Interact 8: 357−370 Lardies MA, Arias MB, Poupin MJ, Manríquez PH and oth-ers (2014) Differential response to ocean acidification in physiological traits of Concholepas concholepas popula-tions. J Sea Res 90: 127−134 Lardies MA, Benítez S, Osores S, Vargas CA, Duarte C, Lohrmann KB, Lagos NA (2017) Physiological and histo - pathological impacts of increased carbon dioxide and temperature on the scallops Argopecten purpuratus cultured under upwelling influences in northern Chile. Aquaculture 479: 455−466 Lemasson AJ, Fletcher S, Hall-Spencer JM, Knights AM (2017) Linking the biological impacts of ocean acidifica-tion on oysters to changes in ecosystem services: a review. J Exp Mar Biol Ecol 492: 49−62 Mackenzie CL, Ormondroyd GA, Curling SF, Ball RJ, Whitely NM, Malham SK (2014) Ocean warming, more than acidification, reduces shell strength in a commercial shellfish species during food limitation. PLOS ONE 9: e86764 McElhany P (2017) CO2 sensitivity experiments are not suf-ficient to show an effect of ocean acidification. ICES J Mar Sci 74: 926−928 Mehrbach C, Culberson CH, Hawley JE, Pytkowicz RM (1973) Measurement of the apparent dissociation con-stants of carbonic acid in seawater at atmospheric pres-sure. Limnol Oceanogr 18: 897−907 Melzner F, Thomsen J, Koeve W, Oschlies A and others (2013) Future ocean acidification will be amplified by hypoxia in coastal habitats. Mar Biol 160: 1875−1888 Michaelidis B, Ouzounis C, Paleras A, Pörtner HO (2005) Effects of long-term moderate hypercapnia on acid−base balance and growth rate in marine mussels Mytilus gal-loprovincialis. Mar Ecol Prog Ser 293: 109−118 Miller AW, Reynolds AC, Sobrino C, Riedel GF (2009) Shell-fish face uncertain future in high CO2 world: influence of acidification on oyster larvae calcification and growth in estuaries. PLOS ONE 4: e5661 Navarro JM (1988) The effects of salinity on the physio - logical ecology of Choromytilus chorus (Molina, 1782) (Bivalvia: Mytilidae). J Exp Mar Biol Ecol 122: 19−33 Navarro JM, Torres R, Acuña K, Duarte C and others (2013) Impact of medium-term exposure to elevated pCO2 lev-els on the physiological energetics of the mussel Mytilus chilensis. Chemosphere 90: 1242−1248 Navarro JM, Duarte C, Manríquez PH, Lardies MA and oth-ers (2016) Ocean warming and elevated carbon dioxide: multiple stressor impacts on juvenile mussels from south-ern Chile. ICES J Mar Sci 73: 764−771 Nienhuis S, Palmer AR, Harley CD (2010) Elevated CO2 affects shell dissolution rate but not calcification rate in a marine snail. Proc R Soc B 277: 2553−2558 Orr JC, Fabry VJ, Aumont O, Bopp L and others (2005) Anthropogenic ocean acidification over the twenty-first century and its impact on calcifying organisms. Nature 437: 681−686 Osores SJ, Lagos NA, San Martin V, Manríquez PH and others (2017) Plasticity and inter-population variability in physiological and life-history traits of the mussel Mytilus chilensis: a reciprocal transplant experiment. J Exp Mar Biol Ecol 490: 1−12 Palmer AR (1982) Growth in marine gastropods: a non-destructive technique for independently measuring shell and body weight. Malacologia 23: 63−73 Parker LM, Ross PM, O’Connor WA, Borysko L, Raftos DA, Pörtner HO (2012) Adult exposure influences offspring response to ocean acidification in oysters. Glob Change Biol 18: 82−92 Pierrot D, Lewis E, Wallace DWR (2006) MS Excel program developed for CO2 system calculations. ORNL/CDIAC-105a. Carbon Dioxide Information Analysis Center, Oak Ridge National Laboratory, US Department of Energy, Oak Ridge, TN Ramajo L, Marba N, Prado L, Peron S and others (2016) Bio-mineralization changes with food supply confer juvenile scallops (Argopecten purpuratus) resistance to ocean acidification. Glob Change Biol 22: 2025−2037 Range P, Chícharo MA, Ben-Hamadou R, Piló D and others (2014) Impacts of CO2-induced seawater acidification on coastal Mediterranean bivalves and interactions with other climatic stressors. Reg Environ Change 14(Suppl 1): 19−30 Sabine C, Feely RA, Gruber N, Key RM and others (2004) The oceanic sink of anthropogenic CO2. Science 305: 367–371 SERNAPESCA (Servicio Nacional de Pesca y Acuicultura) (2014) Anuarios estadísticos del Servicio Nacional de Pesca y Acuicultura. www.sernapesca.cl Solórzano L (1969) Determination of ammonia in natural waters by the phenolhypochlorite method. Limnol Oce - anogr 14: 799−801 Thomsen J, Melzner F (2010) Moderate seawater acidifica-tion does not elicit long-term metabolic depression in the blue mussel Mytilus edulis. Mar Biol 157: 2667−2676 Thomsen J, Casties I, Pansch C, Körtzinger A, Melzner F (2013) Food availability outweighs ocean acidification effects in juvenile Mytilus edulis: laboratory and field experiments. Glob Change Biol 19: 1017−1027 Thomsen J, Stapp LS, Haynert K, Schade H, Danelli M, Lannig G, Melzner F (2017) Naturally acidified habitat selects for ocean acidification-tolerant mussels. Sci Adv 3: e1602411 Toro B, Navarro JM, Palma-Fleming H (2003) Relationship between bioenergetics responses and organic pollutants in the giant mussel, Choromytilus chorus (Mollusca: Mytilidae). Aquat Toxicol 63: 257−269 Torres R, Pantoja S, Harada N, González HE, Daneri G, Frangopulos M, Fukasawa M (2011) Air-sea CO2 fluxes along the coast of Chile: from CO2 outgassing in central northern upwelling waters to CO2 uptake in southern Patagonian fjords. J Geophys Res 116: C09006 Torres R, Manriquez PH, Duarte C, Navarro JM, Lagos NA, Vargas CA, Lardies MA (2013) Evaluation of a semi - automatic system for long-term seawater carbonate chemistry manipulation. Rev Chil Hist Nat 86: 443−451 Vargas CA, Aguilera V, Martín V, Manríquez P and others (2015) CO2-driven ocean acidification disrupts the filter feeding behavior in Chilean gastropod and bivalve spe-cies from different geographic localities. Estuaries Coasts 38: 1163−1177 Vargas CA, Lagos NA, Lardies MA, Duarte C and others (2017) Species-specific responses to ocean acidification should account for local adaptation and adaptive plasti-city. Nature Ecol Evol 1: 0084 Vargas CA, Cuevas LA, Silva N, Gonzalez HE, Pol-Holz D, Narvaez DA (2018) Influence of glacier melting and river discharges on the nutrient distribution and DIC recycling in the southern Chilean Patagonia. J Geophys Res Bio-geosci 123: 256−270 Velasco LA, Navarro JM (2003) Energetic balance of infau-nal (Mulinia edulis King, 1831) and epifaunal (Mytilus chilensis Hupé, 1854) bivalves in response to wide varia-tions in concentration and quality of seston. J Exp Mar Biol Ecol 296: 79−92 Vihtakari M, Hendriks IE, Holding J, Renaud PE, Duarte CM, Havenhand JN (2013) Effects of ocean acidification and warming on sperm activity and early life stages of the Mediterranean mussel (Mytilus galloprovincialis). Water 5: 1890−1915 Wang Y, Li L, Hu M, Lu W (2015) Physiological energetic of the thick shell mussel Mytilus coruscus exposed to sea-water acidification and thermal stress. Sci Total Environ 514: 261−272 White MM, McCorkle DC, Mullineaux LS, Cohen AL (2013)Benthic habitats such as intertidal areas, sandy or rocky shores, upwelling zones, and estuaries are characterized by variable environmental conditions. This high variability of environmental stressors such as temperature, salinity, and pH/pCO 2 levels have been shown to impose restrictions on organismal performance. The giant mussel Choromytilus chorus forms intertidal and subtidal mussel beds in estuarine zones associated with fjords occurring in southern Chile and is an important aquacultural resource in Patagonia. In this study, we estimated the sensitivity of physiological traits and energy balance of C. chorus juveniles exposed to 3 pCO 2 treatments (500, 750, and 1200 μatm) for 30 d. Results showed that in acidified, high pCO 2 conditions, C. chorus juveniles had increased metabolic rates; however, other physiological traits (clearance and ingestion rates, ammonia excretion, absorption efficiency, growth rate, biomass production, net calcification, and dissolution rates) were not affected. These results suggest that when subjected to acidification, the adaptive response of C. chorus triggers tradeoffs among physiological traits that favor sustained feeding and growth in order to combat increased metabolic stress. As has been reported for other marine organisms, chronic exposure to variable pH/pCO 2 in their native habitats, such as estuarine zones, could explain the differential acclimatization capacity of giant mussels to cope with the increase in pCO 2 . Additionally, the fact that the mussels did not suffer from mortality indicates that increased pCO 2 levels may have chronic, but not lethal, effects on this species under these experimental conditions. © The authors 2017.https://www.int-res.com/abstracts/aei/v10/p267-278

Using airborne LiDAR Survey to explore historic-era archaeological landscapes of Montserrat in the eastern Caribbean

This article describes what appears to be the first archaeological application of airborne LiDAR survey to historic-era landscapes in the Caribbean archipelago, on the island of Montserrat. LiDAR is proving invaluable in extending the reach of traditional pedestrian survey into less favorable areas, such as those covered by dense neotropical forest and by ashfall from the past two decades of active eruptions by the Soufrière Hills volcano, and to sites in localities that are inaccessible on account of volcanic dangers. Emphasis is placed on two aspects of the research: first, the importance of ongoing, real-time interaction between the LiDAR analyst and the archaeological team in the field; and second, the advantages of exploiting the full potential of the three-dimensional LiDAR point cloud data for purposes of the visualization of archaeological sites and features

Transport properties of copper phthalocyanine based organic electronic devices

Ambipolar charge carrier transport in Copper phthalocyanine (CuPc) is studied experimentally in field-effect transistors and metal-insulator-semiconductor diodes at various temperatures. The electronic structure and the transport properties of CuPc attached to leads are calculated using density functional theory and scattering theory at the non-equilibrium Green's function level. We discuss, in particular, the electronic structure of CuPc molecules attached to gold chains in different geometries to mimic the different experimental setups. The combined experimental and theoretical analysis explains the dependence of the mobilityand the transmission coefficient on the charge carrier type (electrons or holes) and on the contact geometry. We demonstrate the correspondence between our experimental results on thick films and our theoretical studies of single molecule contacts. Preliminary results for fluorinated CuPc are discussed.Comment: 18 pages, 16 figures; to be published in Eur. Phys. J. Special Topic

Prognostic significance of epithelial-mesenchymal transition in malignant pleural mesothelioma

Background: Epithelial-to-mesenchymal transition (EMT) is a morphologic transdifferentiation of carcinomas, conferring increased tumour invasiveness, but may also be applied to the epithelioid versus sarcomatoid histotype of malignant pleural mesothelioma (MPM). Herein, we correlated proteins of a putative MPM-EMT axis, including periostin, epidermal growth factor receptor (EGFR), integrin beta1, phosphatase and tensin homologue (PTEN), integrin-linked kinase (ILK), p21 and p27, with clinico-pathologic parameters, in particular overall survival (OS). Patients and Methods: A retrospective cohort of 352 mostly untreated patients with MPM was investigated by immunohistochemistry of a tissue microarray. Protein expression intensities were semi-quantitatively scored from 0 to 3 in their respective compartments, including peritumoural stroma as well as tumour cell plasma membrane, cytoplasm or nucleus. Data were correlated with histotype and survival outcome. Results: A total of 32% of the tumours were diagnosed as epithelioid, 13% as sarcomatoid and 55% as biphasic histotype. High expression of membranous EGFR and integrin beta1 as well as nuclear p27 correlated with the epithelioid and high expression of cytoplasmic tumoural and stromal periostin with the sarcomatoid histotype. The median survival time of the 128 patients with complete follow-up data was 11.7 months. Univariate survival analysis revealed age, epithelioid histotype and any therapy as prognosticators for better OS. High expression of cytoplasmic PTEN or ILK as well as high expression of nuclear p21 or p27 correlated with increased, whereas high expression of cytoplasmic periostin with decreased OS (all p values <0.05). Multivariate Cox regression revealed any treatment, low cytoplasmic periostin and high cytoplasmic PTEN as independent prognosticators for better OS. Conclusion: Activation of periostin-triggered EMT is associated with the sarcomatoid histotype and has an impact on shorter survival of MPM patients. Finally, only the high expression of PTEN and the low expression of cytosolic periostin could be shown to be independent prognostic factors for longer O

From bi-layer to tri-layer Fe nanoislands on Cu3Au(001)

Self assembly on suitably chosen substrates is a well exploited root to control the structure and morphology, hence magnetization, of metal films. In particular, the Cu3Au(001) surface has been recently singled out as a good template to grow high spin Fe phases, due to the close matching between the Cu3Au lattice constant (3.75 Angstrom) and the equilibrium lattice constant for fcc ferromagnetic Fe (3.65 Angstrom). Growth proceeds almost layer by layer at room temperature, with a small amount of Au segregation in the early stage of deposition. Islands of 1-2 nm lateral size and double layer height are formed when 1 monolayer of Fe is deposited on Cu3Au(001) at low temperature. We used the PhotoElectron Diffraction technique to investigate the atomic structure and chemical composition of these nanoislands just after the deposition at 140 K and after annealing at 400 K. We show that only bi-layer islands are formed at low temperature, without any surface segregation. After annealing, the Fe atoms are re-aggregated to form mainly tri-layer islands. Surface segregation is shown to be inhibited also after the annealing process. The implications for the film magnetic properties and the growth model are discussed.Comment: Revtex, 5 pages with 4 eps figure