EP-1711: Effect of Noise Floor Suppression on Diffusion Kurtosis for Prostate Brachytherapy

WOS: 000467786304224

Photometry and the Metallicity Distribution of the Outer Halo of M31

We have conducted a wide-field CCD-mosaic study of the resolved red-giant branch (RGB) stars of M31, in a field located 20 kpc from the nucleus along the SE minor axis. In our (I, V-I) color-magnitude diagram, RGB stars in the top three magnitudes of the M31 halo are strongly present. Photometry of a more distant control field to subtract field contamination is used to derive the `cleaned' luminosity function and metallicity distribution function (MDF) of the M31 halo field. From the color distribution of the foreground Milky Way halo stars, we find a reddening E(V-I)= 0.10 +/- 0.02 for this field, and from the luminosity of the RGB tip, we determine a distance modulus (m-M)_o = 24.47 +/- 0.12 (= 783 +/- 43 kpc). The MDF is derived from interpolation within an extensive new grid of RGB models (Vandenberg et al. 2000). The MDF is dominated by a moderately high-metallicity population ([m/H]~ -0.5) found previously in more interior M31 halo/bulge fields, and is much more metal-rich than the [m/H]~ -1.5 level in the Milky Way halo. A significant (~30% - 40%, depending on AGB star contribution) metal-poor population is also present. To first order, the shape of the MDF resembles that predicted by a simple, single-component model of chemical evolution starting from primordial gas with an effective yield y=0.0055. It strongly resembles the MDF recently found for the outer halo of the giant elliptical NGC 5128 (Harris et al. 2000), though NGC 5128 has an even lower fraction of low-metallicity stars. Intriguingly, in both NGC 5128 and M31, the metallicity distribution of the globular clusters in M31 does not match the halo stars; the clusters are far more heavily weighted to metal-poor objects. We suggest similarities in the formation and early evolution of massive, spheroidal stellar systems.Comment: to appear in the Astronomical Journal; 43 pages, including 15 figure

Mutational analysis of Sse1 (Hsp110) suggests an integral role for this chaperone in yeast prion propagation in vivo.

The yeast Hsp110 chaperone Sse1 is a conserved protein that is a noncanonical member of the Hsp70 protein superfamily. Sse1 influences the cellular response to heat stress and has also been implicated in playing a role in the propagation of prions in yeast. Sse1 can seemingly exert its effects in vivo through direct or indirect actions by influencing the nucleotide exchange activity of canonical cytosolic Hsp70s. Using a genetic screen based on the inability to propagate the yeast [PSI(+)] prion, we have identified 13 new Sse1 mutants that are predicted to alter chaperone function through a variety of different mechanisms. Not only are these new Sse1 mutants altered in the ability to propagate and cure yeast prions but also to varying degrees in the ability to grow at elevated temperatures. The expression levels of chaperone proteins known to influence yeast prion propagation are unaltered in the Sse1 mutants, suggesting that the observed phenotypic effects are caused by direct functional alterations in these mutants. Mapping the location of the mutants onto the Sse1 crystal structure suggests that more than one functional alteration in Sse1 may result in changes in prion propagation and ability to function at elevated temperatures. All Sse1 mutants isolated provide essential functions in the cell under normal growth conditions, further demonstrating that essential chaperone functions in vivo can to some degree at least be detached from those related to propagation of prions. Our results suggest that Sse1 can influence prion propagation through a variety of different mechanisms

Cross-cultural effects of color, but not morphological masculinity, on perceived attractiveness of men's faces

This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2012 ElsevierMuch attractiveness research has focused on face shape. The role of masculinity (which for adults is thought to be a relatively stable shape cue to developmental testosterone levels) in male facial attractiveness has been examined, with mixed results. Recent work on the perception of skin color (a more variable cue to current health status) indicates that increased skin redness, yellowness, and lightness enhance apparent health. It has been suggested that stable cues such as masculinity may be less important to attractiveness judgments than short-term, more variable health cues. We examined associations between male facial attractiveness, masculinity, and skin color in African and Caucasian populations. Masculinity was not found to be associated with attractiveness in either ethnic group. However, skin color was found to be an important predictor of attractiveness judgments, particularly for own-ethnicity faces. Our results suggest that more plastic health cues, such as skin color, are more important than developmental cues such as masculinity. Further, unfamiliarity with natural skin color variation in other ethnic groups may limit observers' ability to utilize these color cues

The Kinematics and Metallicity of the M31 Globular Cluster System

With the ultimate aim of distinguishing between various models describing the formation of galaxy halos (e.g. radial or multi-phase collapse, random mergers), we have completed a spectroscopic study of the globular cluster system of M31. We present the results of deep, intermediate-resolution, fibre-optic spectroscopy of several hundred of the M31 globular clusters using the Wide Field Fibre Optic Spectrograph (WYFFOS) at the William Herschel Telescope in La Palma, Canary Islands. These observations have yielded precise radial velocities (+/-12 km/s) and metallicities (+/-0.26 dex) for over 200 members of the M31 globular cluster population out to a radius of 1.5 degrees from the galaxy center. Many of these clusters have no previous published radial velocity or [Fe/H] estimates, and the remainder typically represent significant improvements over earlier determinations. We present analyses of the spatial, kinematic and metal abundance properties of the M31 globular clusters. We find that the abundance distribution of the cluster system is consistent with a bimodal distribution with peaks at [Fe/H] = -1.4 and -0.5. The metal-rich clusters demonstrate a centrally concentrated spatial distribution with a high rotation amplitude, although this population does not appear significantly flattened and is consistent with a bulge population. The metal-poor clusters tend to be less spatially concentrated and are also found to have a strong rotation signature.Comment: 33 pages, 20 figure

Spectroscopy of globular clusters in the low-luminosity spiral galaxy NGC 45

CONTEXT: Extragalactic globular clusters have been studied in elliptical galaxies and in a few luminous spiral galaxies, but little is known about globular clusters in low-luminosity spirals. AIMS: Past observations with the ACS have shown that NGC 45 hosts a large population of globular clusters (19), as well as several young star clusters. In this work we aim to confirm the bona fide globular cluster status for 8 of 19 globular cluster candidates and to derive metallicities, ages, and velocities. METHODS: VLT/FORS2 multislit spectroscopy in combination with the Lick/IDS system was used to derive velocities and to constrain metallicities and [alpha/Fe] element ratio of the globular clusters. RESULTS: We confirm the 8 globular clusters as bona fide globular clusters. Their velocities indicate halo or bulge-like kinematics, with little or no overall rotation. From absorption indices such as H_beta, H_gamma, and H_delta and the combined [MgFe]' index, we found that the globular clusters are metal-poor [Z/H]<=-0.33 dex and [alpha/Fe]<=0.0 element ratio. These results argue in favor of a population of globular clusters formed during the assembling of the galaxy.Comment: Accepted for publication in Astronomy and Astrophysics. 10 pages, 6 figures. Table 6 and Fig. 6 will only be published in the electronic edition of the A&A journa

HST/ACS colour-magnitude diagrams of M31 globular clusters

With the aim of increasing the sample of M31 clusters for which a colour magnitude diagram is available, we searched the HST archive for ACS images containing objects included in the Revised Bologna Catalogue of M31 globular clusters. Sixty-three such objects were found. We used the ACS images to confirm or revise their classification and we obtained useful CMDs for 11 old globular clusters and 6 luminous young clusters. We obtained simultaneous estimates of the distance, reddening, and metallicity of old clusters by comparing their observed field-decontaminated CMDs with a grid of template clusters of the Milky Way. We estimated the age of the young clusters by fitting with theoretical isochrones. For the old clusters, we found metallicities in the range -0.4<=[Fe/H]<=-1.9, that generally agree with existing spectroscopic extimates. At least four of them display a clear blue HB, indicating ages >10 Gyr. All six candidate young clusters are found to have ages <1Gyr. With the present work the total number of M31 GCs with reliable optical CMD increases from 35 to 44 for the old clusters, and from 7 to 11 for the young ones. The old clusters show similar characteristics to those of the MW. We discuss the case of the cluster B407, with a metallicity [Fe/H] ~-0.6 and located at a large projected distance from the centre of M31 and from the galaxy major axis. Metal-rich globulars at large galactocentric distances are rare both in M31 and in the MW. B407, in addition, has a velocity in stark contrast with the rotation pattern shared by the bulk of M31 clusters of similar metallicity. This, along with other empirical evidence, supports the hypothesis that the cluster is physically associated with a substructure in the M31 halo that has been interpreted as the relic of a merging event.Comment: 19 pages, 14 figures, 6 tables. Accepted for publication on Astronomy and Astrophysic

2MASS NIR photometry for 693 candidate globular clusters in M31 and the Revised Bologna Catalogue

We have identified in the 2MASS database 693 known and candidate globular clusters in M31. The 2MASS J,H,K magnitudes of these objects have been transformed to the same homogeneous photometric system of existing near infrared photometry of M31 globulars, finally yielding J,H,K integrated photometry for 279 confirmed M31 clusters, 406 unconfirmed candidates and 8 objects with controversial classification. Of these objects 529 lacked any previous estimate of their near infrared magnitudes. The newly assembled near infrared dataset has been implemented into a revised version of the Bologna Catalogue of M31 globulars, with updated optical (UBVRI) photometry taken, when possible, from the most recent sources of CCD photometry available in the literature and transformed to a common photometric system. The final Revised Bologna Catalogue (available in electronic form) is the most comprehensive list presently available of confirmed and candidate M31 globular clusters, with a total of 1164 entries. In particular, it includes 337 confirmed GCs, 688 GC candidates, 10 objects with controversial classification, 70 confirmed galaxies, 55 confirmed stars, and 4 HII regions lying within ~3 deg. from the center of the M31 galaxy. Using the newly assembled database we show that the V-K color provides a powerful tool to discriminate between M31 clusters and background galaxies, and we identify a sample of 83 globular cluster candidates, which is not likely to be contaminated by misclassified galaxies.Comment: 9 pages,5 figures,accepted for publication in Astronomy & Astrophysics ASCII (commented) version of the tables 2,3,4 are available at http://www.bo.astro.it/M3

Adolescents’ preferences for sexual dimorphism are influenced by relative exposure to male and female faces

Exposure to a particular population of faces can increase ratings of the normality and attractiveness of similar-looking faces. Such exposure can also refine the perceived boundaries of that face population, such that other faces are more readily perceived as dissimilar. We predicted that relatively less exposure to opposite-sex faces, as experienced by children at single-sex compared with mixed-sex schools, would decrease ratings of the attractiveness of sexual dimorphism in opposite-sex faces (that is, boys at single-sex schools would show a decreased preference for feminised faces, and girls at single-sex schools would show a decreased preference for masculinised faces). Consistent with this prediction, girls at single-sex compared with mixed-sex schools demonstrated significantly stronger preferences for facial femininity in both male and female faces. Boys at single-sex compared with mixed-sex schools demonstrated marginally stronger preferences for facial masculinity in male faces, but did not differ in their ratings of female faces. These effects were attenuated among some single-sex school pupils by the presence of adolescent opposite-sex siblings. These data add to the evidence that long-term exposure to a particular face population can influence judgements of other faces, and contribute to our understanding of the factors leading to individual differences in face preferences

The Rise Time of Type Ia Supernovae from the Supernova Legacy Survey

We compare the rise times of nearby and distant Type Ia supernovae (SNe Ia) as a test for evolution using 73 high-redshift spectroscopically-confirmed SNe Ia from the first two years of the five year Supernova Legacy Survey (SNLS) and published observations of nearby SN. Because of the ``rolling'' search nature of the SNLS, our measurement is approximately 6 times more precise than previous studies, allowing for a more sensitive test of evolution between nearby and distant supernovae. Adopting a simple $t^2$ early-time model (as in previous studies), we find that the rest-frame $B$ rise times for a fiducial SN Ia at high and low redshift are consistent, with values $19.10^{+0.18}_{-0.17}({stat}) \pm 0.2 ({syst})$ and $19.58^{+0.22}_{-0.19}$ days, respectively; the statistical significance of this difference is only 1.4 \sg . The errors represent the uncertainty in the mean rather than any variation between individual SN. We also compare subsets of our high-redshift data set based on decline rate, host galaxy star formation rate, and redshift, finding no substantive evidence for any subsample dependence.Comment: Accepted for publication in AJ; minor changes (spelling and grammatical) to conform with published versio