464 research outputs found
Radiation studies from meteorological satellites
Earth albedo variability and outgoing infrared radiation - data from TIROS satellite
Equilibrium Temperature Structure in the Mesosphere and Lower Thermosphere
Radiative equilibrium temperature structure in earth mesosphere and lower thermospher
Implementation of Fuzzy Controller for Capacitor Voltage Balance in MMC for PV based Induction Motor Drive
This paper discusses the capacitor voltage balance in MMC controlled by the space vector PWM technique. The proposed converter is included with four sub-modules each comprising a half-bridge converter with a DC link capacitor. An optimized control structure for capacitor voltage balance with the conventional PI controller is simulated compared to the updated visual system controller that changes the standard control. The converter function is analyzed with the comparison of settling times of the DC link capacitors voltages in each module. The performance of the induction motor is analyzed by connected to this converter generating speed and torque characteristic parameters. The architecture and analysis was performed using the MATLAB Simulink software, which uses the powergui function to create time-based graphs
Atomistic to continuum model for studying mechanical properties of RNA nanotubes
With rapid advancements in the emerging field of RNA nanotechnology, its current and potential applications, new important problems arise in our quest to better understand properties of RNA nanocomplexes. In this paper, our focus is on the modeling of RNA nanotubes which are important for many biological processes. These RNA complexes are also important for human beings, with their theurapeuti- cal and biomedical applications discussed vigorously in the literature over the recent years. Here, we develop a continuum model of RNA nanotubes, originally obtained from self assembly of RNA building blocks in the molecular dynamics simulation. Based on the finite element method, we calculate the elastic properties of these nanostructures and provide a relationship between stress and strain induced in the RNA nanotube. We also analyze the variations in the displacement vector along the assembly axis for RNA nanotubes of different sizes. In particular, we show that os- cillations in the amplitudes of strains and displacements significantly differ for such RNA nanotubes. These findings are discussed in the context of atomistic simulations and experimental results in this field
Control of Progressive Collapse of the Structure Using Shear Wall
The vulnerability of reinforced concrete (RC) building systems to progressive collapse has turned out to be a challenging trouble for professionalstructural engineers so as to prevent total failure on account of nearby damage. The goal of this paper is to enhance the knowledge of such buildings’behavior underneath several scenarios of misplaced columns at differentfloor stages, and their capacity for progressive collapse. The homes hadbeen analyzed following the guidelines for progressive collapse evaluation and design organized by means of the general services administrationguidelines (GSA). The progressive collapse of a ten story structure subjected to a simplest gravity load is taken into consideration and the columnhas been eliminated at one place and the spread damage is evaluated. Theprogressive collapse study has been carried out by way of removing thecolumn at a diagnosed crucial locations (at corner, middle and at interior) as in line with GSA guidelines. Static analysis is done using analysisprogram ETABS. For each case, the consequences were taken in terms ofdemand capacity ratio (DCR) at critical section, and as a result the structurehas been assessed for it’s susceptible to progressive collapse. The availability of shear wall is made on the component wherein collapse occurred andDCR values are mentioned. After imparting the shear wall to the structure,the progressive collapse of the structure because of accidental load maybe controlled in order that the GSA guidelines recommended DCR valuewould be within the range
Transition Metal Complexes of Quinolino[3,2-b]benzodiazepine and Quinolino[3,2-b]benzoxazepine: Synthesis, Characterization, and Antimicrobial Studies
The synthesis and characterization of title complexes of the ligand Quinolino[3,2-b]benzodiazepine (QBD) and Quinolino[3,2-b]benzoxazepine (QBO) are reported. The complexes have been characterized by elemental analysis, molar conductance, magnetic studies, IR, H1 NMR, and UV-visible studies. They have the stoichiometry [ML2C12], where M=Co(II)/Ni(II), L=QBD/QBO, and [MLC12], where M=Zn(II)/Cd(II), L=QBD/QBO. The antibacterial and antifungal activity of the metal complexes has been investigated. The complexes were found to have
higher antimicrobial activity than the parent ligand
Co(III) and Ni(II) Complexes Containing Bioactive Ligands: Synthesis, DNA Binding, and Photocleavage Studies
DNA binding and photocleavage characteristics of a series of
mixed ligand complexes of the type [M(bpy)2qbdp](PF6)n·xH2O (where M = Co(III) or Ni(II), bpy = 2.2′-bipryidine, qbdp = Quinolino[3,2-b]benzodiazepine, n = 3 or 2 and x = 5 or 2) have been investigated. The DNA binding property of the complexes with calf
thymus DNA has been investigated by using absorption spectra,
viscosity measurements, as well as thermal denaturation studies.
Intrinsic binding constant (Kb) has been estimated under similar set of experimental conditions. Absorption spectral studies
indicate that the Co(III) and Ni(II) complexes intercalate between
the base pairs of the CT-DNA tightly with intrinsic DNA binding
constant of 1.3 × 106 and 3.1 × 105
M−1 in Tris-HCl buffer containing 50 mM
NaCl, respectively. The proposed DNA binding mode supports
the large enhancement in the relative viscosity of DNA on binding
to quinolo[3,2-b]benzodiazepine. The oxidative as well as photo-induced cleavage reactions were monitered by gel electrophoresis for both complexes. The photocleavage experiments showed that the cobalt(III) complex can cleave pUC19 DNA effectively in the
absence of external additives as an effective inorganic nuclease
Prevalence of subclinical hypothyroidism in children and adolescents of northern Andhra Pradesh population and its association with hyperlipidemia
Background: The thyroid dysfunction particularly, subclinical hypothyroidism (SCH) is quite a common clinical condition in paediatric population but there is limited data available regarding its prevalence in children and adolescents in our population. The present study was aimed to know the prevalence of thyroid dysfunction particularly SCH in children and adolescents of northern Andhra Pradesh population and its association with hyperlipidemia.Methods: A retrospective study of 600 subjects (Children=272, Adolescents=328) between 6-19 years of age were included and the following parameters were examined: age, sex, total triiodothyronine (tT3), total tetraiodothyronine (tT4), thyroid stimulating hormone (TSH), total cholesterol, triglycerides (TGL), LDL and HDL cholesterol. The subjects were divided into group I and group II on the basis of age (in years), subjects between 6- ≤12 years age were grouped as group I and 12-≤19 years were as group II.Results: Out of 272 children and 328 adolescents studied, the prevalence of thyroid dysfunction was found to be 9.9% and 10.4 % respectively. The prevalence of subclinical hypothyroidism in children was 7.7% where as 4.9% in adolescents. In both the groups, females were predominantly affected with thyroid dysfunction as compared to males. Significantly elevated serum levels of total cholesterol, TSH and TGL were observed in SCH subjects when compared to euthyroid subjects (p<0.05). Statistically significant lower levels of HDL cholesterol were found in SCH as compared to euthyroids (p<0.05). However, no difference was noticed in the levels of total T3, total T4 and LDL cholesterol between SCH and euthyroids.Conclusions: The prevalence of thyroid dysfunction was found to be 10.2% in study population. SCH was observed in 7.7 % and 4.9% respectively in children and adolescent groups. Subclinical hypothyroidism (SCH) was the most predominant thyroid dysfunction found in our studied population with a prevalence of 6.2% (both children and adolescents). Correction of thyroid dysfunction particularly SCH in early childhood is highly essential to prevent the impairment of psychomotor and cognitive development
Prevalence of thyroid dysfunction and its association with controlled and uncontrolled type 2 diabetes mellitus in northern Andhra Pradesh population: a retrospective study
Background: The two important endocrinopathies, diabetes mellitus and thyroid dysfunction are interrelated to each other where the correlation is poorly understood. The thyroid dysfunction is more frequent in diabetics than general population. The present study was aimed to know the prevalence of thyroid dysfunction in type 2 diabetes mellitus (T2DM) and its association with controlled and uncontrolled T2DM.Methods: A retrospective study of 600 T2DM patients between 13-60 years of age with known thyroid status were included and the following parameters were examined: age, sex, body mass index (BMI), fasting blood sugar (FBS), HbA1C, free triiodothyronine (fT3), free tetraiodothyronine (fT4) and thyroid stimulating hormone (TSH).Results: The prevalence of thyroid dysfunction in T2DM patients was found to be 26.5% whereas 9% in healthy controls. Significantly elevated levels of FBS, HbA1C and TSH were observed whereas the levels of fT3, fT4 were found to be low in patients when compared to controls. Subclinical hypothyroidism (SCH) in diabetics (both controlled and uncontrolled) was more prevalent (15%) than it was found in healthy controls (5%). Similarly, overt hypothyroidism was also found to be high in diabetic patients (6%) as compared to healthy controls (2%). Significant difference (p <0.05) in the levels of TSH was found between group I (Controlled T2DM) and II (uncontrolled T2DM patients), also between groups II and III (Controls). Group II patients were found to have significant low levels of fT3 as compared to other two groups (Group I and III) (p<0.005).Conclusions: As SCH is more frequent in T2DM diabetes mellitus and untreated SCH patients have higher rate of complications, periodical screening is advised for thyroid dysfunction to prevent micro vascular and cardiovascular complications
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