Dramatic Battles in Eighteenth-Century France: Philosophes, Anti-philosophes, and Polemical Theatre

Traditionally, the essay contest has occupied a relatively minor place in histories of the Enlightenment public sphere, discussion of its contribution to the intellectual and literary life of eighteenth-century France being largely limited to passing references in descriptions of the parent Academies. Jeremy Caradonna aims to rehabilitate the role of the essay contest, elucidating its distinctive contribution to Enlightenment practice and arguing that it provides an important new outlook on the contemporary public sphere

A critical analysis of the UV-continuum slopes of high-redshift galaxies; no evidence (yet) for extreme stellar populations at z > 6

It has recently been reported that the faintest galaxies at z~6-7 display extremely blue UV continuum slopes, with a UV power-law index beta ~ -3. Such slopes are bluer than previously reported for any other galaxy population, and imply extinction-free, young, very low-metallicity stellar populations with a high ionizing photon escape fraction. Here we undertake a critical study of the evidence for such extreme values of beta, combining three new WFC3/IR-selected samples of galaxies spanning ~2 decades in UV luminosity over the redshift range z~4.5-8. We explore the impact of inclusion/exclusion of less robust high-z candidates, and use the varying depths of the samples to explore the effects of noise and selection bias. Simple data-consistency arguments suggest that artificially blue average values of beta can result when the analysis is extended into the deepest ~ 0.5-mag bin of these WFC3/IR-selected samples, regardless of the actual luminosity or z range probed. By confining attention to robust, well-detected high-z galaxy candidates, we find that the average value of beta is consistent with -2.05 +/- 0.10 for z=5-7, and -22 < M_UV < -18. We create and analyse a set of simulations which demonstrate that a bias towards artifically low/blue average values of beta is indeed expected when the UV slope analysis is extended towards the source detection threshold, and conclude that there is as yet no clear evidence for UV slopes significantly bluer than beta ~ -2, the typical value displayed by the bluest star-forming galaxies at more modest z. A robust measurement of beta for the faintest galaxies at z~7-8 remains a key observational goal, as it provides a fundamental test for high escape fractions from a potentially abundant source of reionizing photons. This goal is achievable with HST, but requires still deeper WFC3/IR imaging in the HUDF.Comment: 12 pages, 10 figures, minor modifications made to make arXiv version match the accepted/published MNRAS versio

Probing Plasmodium falciparum sexual commitment at the single-cell level

Background: Malaria parasites go through major transitions during their complex life cycle, yet the underlying differentiation pathways remain obscure. Here we apply single cell transcriptomics to unravel the program inducing sexual differentiation in Plasmodium falciparum. Parasites have to make this essential life-cycle decision in preparation for human-to-mosquito transmission. Methods: By combining transcriptional profiling with quantitative imaging and genetics, we defined a transcriptional signature in sexually committed cells. Results: We found this transcriptional signature to be distinct from general changes in parasite metabolism that can be observed in response to commitment-inducing conditions. Conclusions: This proof-of-concept study provides a template to capture transcriptional diversity in parasite populations containing complex mixtures of different life-cycle stages and developmental programs, with important implications for our understanding of parasite biology and the ongoing malaria elimination campaign

Magnetic influence on the frequency of the soft-phonon mode in the incipient ferroelectric EuTiO3

The dielectric constant of the incipient ferroelectric EuTiO$_3$ exhibits a sharp decrease at about 5.5K, at which temperature antiferromagnetic ordering of the Eu spins simultaneously appears, indicating coupling between the magnetism and dielectric properties. This may be attributed to the modification of the soft-phonon mode, $T_{1\mu}$, which is the main contribution to the large dielectric constant, by the Eu spins(7$\mu_B$ per Eu). By adding the coupling term between the magnetic and electrical subsystems as $-g\sum\limits_l {\sum\limits_{< {i,j}} {q_l^2}} \overrightarrow {S_i} \cdot \overrightarrow {S_j}$ we show that the variation of the frequency of soft-phonon mode depends on the spin correlation between the nearest neighbors Eu spins and is substantially changed under a magnetic field.Comment: 13 pages, 4 figure

Radioelectric Field Features of Extensive Air Showers Observed with CODALEMA

Based on a new approach to the detection of radio transients associated with extensive air showers induced by ultra high energy cosmic rays, the experimental apparatus CODALEMA is in operation, measuring about 1 event per day corresponding to an energy threshold ~ 5. 10^16 eV. Its performance makes possible for the first time the study of radio-signal features on an event-by-event basis. The sampling of the magnitude of the electric field along a 600 meters axis is analyzed. It shows that the electric field lateral spread is around 250 m (FWHM). The possibility to determine with radio both arrival directions and shower core positions is discussed.Comment: Accepted for publication in Astroparticle Physic

Epidemiological surveys of camel trypanosomosis in Al-jouf, Saudi Arabia based on PCR and ELISA

Trypanosomosis due to Trypanosoma evansi (surra) is a major enzootic disease of the dromedary camel. The present study was conducted to determine the prevalence of camel trypanosomosis in the northern part of Saudi Arabia with different methods of diagnosis (ELISA, PCR) and to compare the results to whose obtained previously with Card Agglutination Test for Trypanosomiasis (CATT/T.evansi). A total of 195 blood samples and 118 serum samples were used for molecular and serological investigation respectively. After analyses, 25% (49/195) and 3% (4/118) samples were positive using PCR and ELISA respectively. The variability of trypanosomosis was highly significant to the factor moving, location, breed and clinical signs with PCR. The discrepancy between PCR, CATT test and ELISA is likely due to antibodies degradation on spotted papers maintained several weeks at ambient temperature. This is the first molecular diagnosis report which gives a picture of camel trypanosomosis in Al-jouf, Saudi Arabia

The VIMOS VLT Deep Survey :Evolution of the major merger rate since z~1 from spectroscopicaly confirmed galaxy pairs

From the VIMOS VLT Deep Survey we use a sample of 6447 galaxies with I_{AB} < 24 to identify 251 pairs of galaxies, each member with a secure spectroscopic redshift, which are close in both projected separation and in velocity. We find that at z ~ 0.9, 10.9 +/- 3.2 % of galaxies with M_B(z) < -18-Qz are in pairs with separations dr < 20 kpc/h, dv < 500 km/s, and with dM_B < 1.5, significantly larger than 3.76 +/- 1.71 % at z ~ 0.5; we find that the pair fraction evolves as (1+z)^m with m = 2.49 +/- 0.56. For brighter galaxies with M_B(z=0) < -18.77, the pair fraction is higher and its evolution with redshift is somewhat flatter with m=1.88 \pm 0.40, a property also observed for galaxies with increasing stellar masses. Early type, dry mergers, pairs increase their relative fraction from 3 % at z ~ 0.9 to 12 % at z ~ 0.5. We find that the merger rate evolves as N_{mg}=(9.05 +/- 3.76) * 10^{-4}) * (1+z)^{2.43 +/- 0.76}. We find that the merger rate of galaxies with M_B(z) < -18-Qz has significantly evolved since z ~ 1. The merger rate is increasing more rapidly with redshift for galaxies with decreasing luminosities, indicating that the flat evolution found for bright samples is not universal. The merger rate is also strongly dependent on the spectral type of galaxies involved, late type mergers being more frequent in the past, while early type mergers are more frequent today, contributing to the rise in the local density of early type galaxies. About 20 % of the stellar mass in present day galaxies with log(M/M_{sun}) > 9.5 has been accreted through major merging events since z ~ 1, indicating that major mergers have contributed significantly to the growth in stellar mass density of bright galaxies over the last half of the life of the Universe.Comment: 22 pages, 19 figures, accepted in A&