Tharu community's perception on climate changes and their adaptive initiations to withstand its impacts in Western Terai of Nepal

This paper brings out perceptions and observations of Tharu communities (Rana and Chaudhary), inhabitants of Shakarpur VDC of Kanchanpur and Gadariya VDCs of Kailali on climate change and its impacts on their livelihood strategies over the years. In addition, the paper explores some initiatives taken by the local communities to minimize its effects and impacts. Focus Group Discussions (FGD) were organized to collect and analyze vulnerability contexts on climate change and its impact on various sectors like, agriculture, forest, livestock, biodiversity, infrastructure, human casualties and water sources. Similarly, information on available service providers and their contribution was garnered through secondary sources. Local communities are facing these changes over the time and adapting strategies as per their own traditional knowledge, skills and information. Most of these strategies are biodiversity friendly, economically viable and socially acceptable. However, these innovative steps should be shared for larger scale dissemination after validating with scientific review and justifications

Influence of Postharvest Treatment of Oxalic Acid on Shelf Life and Quality of Litchi Fruit cv. Muzaffarpur

A lab experiment was conducted in central laboratory of AFU, Rampur, Chitwan, Nepal, in first week of June in 2015 to assess the influence of acid on the pericarp browning and other keeping quality of litchi fruits after harvest. The experiment was carried out in Completely Randomized Design comprising five treatments; control, distilled water dipping for 5 minutes, oxalic acid @ 1%, oxalic acid @ 3% and oxalic acid @ 5% with four replications. The fruits treated with oxalic acid @ 5% retained more acceptable colour than those on other treatments. The cumulative physiological loss in weight (PLW) was minimum (9.15 %) with oxalic acid @ 5% treated fruits. Also, minimum spoilage loss of 13.9 % was found in the treatment oxalic acid @ 5% as compare to control. Thus, oxalic acid @ 5% was observed promising to improve the shelf life of litchi fruits after harvest so that fruits could be kept in better condition for about 10 days

Experts warn Nepal Government not to reduce local Public Health spending

The health system in Nepal is currently undergoing some very interesting radical reforms. The new Constitution in 2015 brought a complete restructuring of the country’s political system, creating a Federal Republic with seven Provinces. This change involves a significant devolution of power and resources from central to local level in many sectors including the health sector. This editorial warns of the risk of moving away the political focus from Public Health in a centralised political syste

Injury and Mortality in Young Nepalese Migrant Workers: A Call for Public Health Action

Approximately 3.5 million Nepalese are working as migrant workers in the Gulf countries, Malaysia, and India. Every year there are more than 1000 deaths and many hundreds cases of injuries among Nepalese workers in these countries excluding India. A postmortem examination of migrant workers is not carried out in most of these countries, and those with work-related injuries are often sent back to home. Uninsured migrant workers also do not have easy access to health care services in host countries due to the high medical and hospital fees. Greater efforts are needed to protect the health and well-being, labor rights, and human rights of migrant workers from Nepal and other South- Asian nations. There is a need to enforce universal labor laws in these countries and to develop accurate records of mortality and morbidity and their causes

Nkx2-5 and Sarcospan genetically interact in the development of the muscular ventricular septum of the heart

The muscular ventricular septum separates the flow of oxygenated and de-oxygenated blood in air-breathing vertebrates. Defects within it, termed muscular ventricular septal defects (VSDs), are common, yet less is known about how they arise than rarer heart defects. Mutations of the cardiac transcription factor NKX2-5 cause cardiac malformations, including muscular VSDs. We describe here a genetic interaction between Nkx2-5 and Sarcospan (Sspn) that affects the risk of muscular VSD in mice. Sspn encodes a protein in the dystrophin-glycoprotein complex. Sspn knockout (Sspn(KO)) mice do not have heart defects, but Nkx2-5(+/−)/Sspn(KO) mutants have a higher incidence of muscular VSD than Nkx2-5(+/−) mice. Myofibers in the ventricular septum follow a stereotypical pattern that is disrupted around a muscular VSD. Subendocardial myofibers normally run in parallel along the left ventricular outflow tract, but in the Nkx2-5(+/−)/Sspn(KO) mutant they commonly deviate into the septum even in the absence of a muscular VSD. Thus, Nkx2-5 and Sspn act in a pathway that affects the alignment of myofibers during the development of the ventricular septum. The malalignment may be a consequence of a defect in the coalescence of trabeculae into the developing ventricular septum, which has been hypothesized to be the mechanistic basis of muscular VSDs

Why do women not use antenatal services in low and middle income countries? A metasynthesis of qualitative studies

Background: Almost 50% of women in low & middle income countries (LMIC’s) don’t receive adequate antenatal care. Women’s views can offer important insights into this problem. Qualitative studies exploring inadequate use of antenatal services have been undertaken in a range of countries, but the findings are not easily transferable. We aimed to inform the development of future antenatal care programmes through a synthesis of findings in all relevant qualitative studies. Methods and Findings: Using a pre-determined search strategy, we identified robust qualitative studies reporting on the views and experiences of women in LMIC’s who received inadequate antenatal care. We used meta-ethnographic techniques to generate themes and a line of argument synthesis. We derived policy relevant hypotheses from the findings. We included 21 papers representing the views of more than 1230 women from 15 countries. Three key themes were identified: ‘Pregnancy as socially risky and physiologically healthy’; ‘Resource use and survival in conditions of extreme poverty’and ‘Not getting it right first time’. The line of argument synthesis describes a dissonance between programme design and cultural contexts that may restrict access and discourage return visits. We hypothesize that centralized, risk-focused antenatal care programmes may be at odds with the resources, beliefs and experiences of pregnant women who underuse antenatal services. Conclusions: Our findings suggest that there may be a mis-alignment between current antenatal provision and the social and cultural context of some women in LMIC’s. Antenatal care provision that is theoretically and contextually at odds with local contextual beliefs and experiences are likely to be underused, especially when attendance generates increased personal risks of lost family resource or physical danger during travel; when the promised care is not delivered due to resource constraints; and when women experience covert or overt abuse in care settings