Impalement Thoracoabdominal Trauma Secondary to Falling on Metallic (Iron) Bars: An Extremely Rare and Unique Case

Introduction: Penetrating thoracoabdominal injuries are potentially life threatening due to the associated hemorrhagic shock and visceral injury. Through and through penetrating injury with polytrauma is rarely encountered. Case Presentation: Here we report on a 25-year-old male with penetrating thoracoabdominal injury caused by a metallic (iron) bar projecting from a pillar of a construction site after he fell down from a height. Conclusions: Anesthetic and surgical management was difficult due to the inability to position in supine and rapidly progressing hemorrhagic shock. Surgical management for extraction of this iron bar and intensive monitoring and resuscitation resulted in an uneventful successful outcome

Generalized qudit Choi maps

Following the linear programming prescription of Ref. \cite{PRA72}, the $d\otimes d$ Bell diagonal entanglement witnesses are provided. By using Jamiolkowski isomorphism, it is shown that the corresponding positive maps are the generalized qudit Choi maps. Also by manipulating particular $d\otimes d$ Bell diagonal separable states and constructing corresponding bound entangled states, it is shown that thus obtained $d\otimes d$ BDEW's (consequently qudit Choi maps) are non-decomposable in certain range of their parameters.Comment: 22 page

Application of INAA to determine major elements concentrations in head hair of street children of Isfahan city, Iran

The street children phenomena and the number of street children is an increasing social problem in Isfahan and other big and growing towns. Because of the number of street children and the way that they affect society in childhood and when they become old, it is important to study their health and have baseline data on theire health problems. Hair element analysis is an important tool in the nutritional and environmental pollutions and measuring pollutions and measuring elemental concentrations in recently-grown hair provides a good way of studing their health. This study aimed to assess major element concentrations in the hair of street children in Isfahan using instrumental neutron activation analysis method. Six major elements (Ca, Cl, K, Mg, Na and S) of 17 Iranian street children (Isfahan) were determined. Data analysis found different profiles of the concentrations of Ca, K, Mg and S in samples. These results were discussed with reference to show of nutritional and environmental effects

A biodistribution study of Hemiscorpius lepturus scorpion venom and available polyclonal antivenom in rats

The purpose of the present study was to investigate the biodistribution profile of the venom of Hemiscorpius lepturus, the most dangerous scorpion in Iran. Blood and tissue samples were taken at various predetermined intervals during a 400-minute period for the venom and a 360-minute period for the antivenom in rats. The radio-iodination was carried out using the chloramine-T method. The results showed that the descending order of venom uptake was skin, kidneys and intestine, respectively. The descending order of polyclonal antivenom uptake was kidneys, intestine, heart and lungs. The calculated pharmacokinetic parameters of the venom were Telimination half-life = 521.5 ± 12.6 minutes; Vd/F (apparent volume of distribution) = 14.9 ± 3.3 mL; clearance (CL/F, apparent total clearance of the drug from plasma) 0.02 ± 0.005 mL/minute and for the antivenom Telimination half-life = 113.7 ± 7.4 minutes; Vd/F = 13 ± 1.2 mL and CL/F 0.08 ± 0.01 mL/minute. The pharmacokinetics profile comparison of the venom with that of the antivenom shows that serotherapy may be more effective if administered within 2-4 hours following envenomation by H. lepturus

Titanium dioxide nanoparticles catalyzed synthesis of Hantzsch esters and polyhydroquinoline derivatives

1,4-Dihydropyridine and polyhydroquinoline derivatives have been prepared efficiently in a one-pot synthesis via Hantzsch condensation using nanosized titanium dioxide as a heterogeneous catalyst. The present methodology offers several advantages such as excellent yields, short reaction times (30-120 min), environmentally benign, and mild reaction conditions. The catalyst can be readily separated from the reaction products and recovered in excellent purity for direct reuse

Thermoluminescence behavior of KClXBr1−X: in mixed crystals exposed to gamma radiation

In-doped KClXBr1−X (X=1, 0.75, 0.5, 0.25 and 0) mixed crystal has been grown by the Czochralski method. The segregation coefficient of In was studied by the inductively coupled plasma atomic emission spectrometry (ICP-OES). The crystal structure has been determined using X-ray diffraction (XRD) analysis. The thermoluminescence (TL) characterization of KClXBr1−X mixed crystals, exposed to gamma radiation has been performed. The results show the introduction of the dopants ions induced changes in the TL glow curve structure. The TL results suggest that doped KClXBr1−X mixed crystal has good potential active dosimeter applications for gamma ray irradiation

Prediction of early weight gain during psychotropic treatment using a combinatorial model with clinical and genetic markers.

Psychotropic drugs can induce significant (>5%) weight gain (WG) already after 1 month of treatment, which is a good predictor for major WG at 3 and 12 months. The large interindividual variability of drug-induced WG can be explained in part by genetic and clinical factors. The aim of this study was to determine whether extensive analysis of genes, in addition to clinical factors, can improve prediction of patients at risk for more than 5% WG at 1 month of treatment. Data were obtained from a 1-year naturalistic longitudinal study, with weight monitoring during weight-inducing psychotropic treatment. A total of 248 Caucasian psychiatric patients, with at least baseline and 1-month weight measures, and with compliance ascertained were included. Results were tested for replication in a second cohort including 32 patients. Age and baseline BMI were associated significantly with strong WG. The area under the curve (AUC) of the final model including genetic (18 genes) and clinical variables was significantly greater than that of the model including clinical variables only (AUCfinal: 0.92, AUCclinical: 0.75, P<0.0001). Predicted accuracy increased by 17% with genetic markers (Accuracyfinal: 87%), indicating that six patients must be genotyped to avoid one misclassified patient. The validity of the final model was confirmed in a replication cohort. Patients predicted before treatment as having more than 5% WG after 1 month of treatment had 4.4% more WG over 1 year than patients predicted to have up to 5% WG (P≤0.0001). These results may help to implement genetic testing before starting psychotropic drug treatment to identify patients at risk of important WG