1,806 research outputs found

    A Self-Consistent Method to Assess Air Quality Co-Benefits from US Climate Policies

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    Air quality co-benefits can potentially reduce the costs of greenhouse gas mitigation. However, while many studies of the cost of greenhouse gas mitigation model the full macroeconomic welfare impacts, most studies of air quality co-benefits do not. We employ a US computable general equilibrium economic model previously linked to an air quality modeling system, and enhance it to represent the economy-wide welfare impacts of fine particulate matter. We present a first application of this method to explore the efficiency and the distributional implications of a clean energy standard (CES) and a cap–and–trade (CAT) program that both reduce CO2 emission by 10% in 2030 relative to 2006. We find that co-benefits from fine particulate matter reduction completely offset policy costs by 110% (40% to 190%), transforming the net welfare impact of the CAT into a gain of 1(1 (-5 to 7)billion2005US7) billion 2005 US. For the CES, the corresponding co-benefit (median 8;8; 3 to $14)/tCO2 is a smaller fraction (median 5%; 2% to 9%) of its higher policy cost. The eastern US garners 78% and 71% of co-benefits for the CES and CAT, respectively. By representing the effects of pollution-related morbidities and mortalities as an impact to labor and the demand for health services, we find that the welfare impact per unit of reduced pollution varies by region. These interregional differences can enhance the preference of some regions, like Texas, for a CAT over a CES, or switch the calculation of which policy yields higher co-benefits, compared to an approach that uses one valuation for all regions. This framework could be applied to quantify consistent air quality impacts of other pricing instruments, subnational trading programs, or green tax swaps.The authors gratefully acknowledge the financial support for this work provided by the MIT Joint Program on the Science and Policy of Global Change through a consortium of industrial sponsors and Federal grants. Additionally, the authors acknowledge support from: the US EPA under the Science to Achieve Results (STAR) program (#R834279); MIT's Leading Technology and Policy Initiative; US Department of Energy Office of Science grant DE-FG02-94ER61937; the MIT Energy Initiative Total Energy Fellowship (Saari); and a MIT Martin Family Society Fellowship (Saari)

    Voting and the Cardinal Aggregation of Judgments

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    The paper elaborates the idea that voting is an instance of the aggregation of judgments, this being a more general concept than the aggregation of preferences. To aggregate judgments one must first measure them. I show that such aggregation has been unproblematic whenever it has been based on an independent and unrestricted scale. The scales analyzed in voting theory are either context dependent or subject to unreasonable restrictions. This is the real source of the diverse 'paradoxes of voting' that would better be termed 'voting pathologies'. The theory leads me to advocate what I term evaluative voting. It can also be called utilitarian voting as it is based on having voters express their cardinal preferences. The alternative that maximizes the sum wins. This proposal operationalizes, in an election context, the abstract cardinal theories of collective choice due to Fleming and Harsanyi. On pragmatic grounds, I argue for a three valued scale for general elections

    Symmetry, bifurcation and stacking of the central configurations of the planar 1+4 body problem

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    In this work we are interested in the central configurations of the planar 1+4 body problem where the satellites have different infinitesimal masses and two of them are diametrically opposite in a circle. We can think this problem as a stacked central configuration too. We show that the configuration are necessarily symmetric and the other sattelites has the same mass. Moreover we proved that the number of central configuration in this case is in general one, two or three and in the special case where the satellites diametrically opposite have the same mass we proved that the number of central configuration is one or two saying the exact value of the ratio of the masses that provides this bifurcation.Comment: 9 pages, 2 figures. arXiv admin note: text overlap with arXiv:1103.627

    Expression of Ciona intestinalis AOX causes male reproductive defects in Drosophila melanogaster

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    Background: Mitochondrial alternative respiratory-chain enzymes are phylogenetically widespread, and buffer stresses affecting oxidative phosphorylation in species that possess them. However, they have been lost in the evolutionary lineages leading to vertebrates and arthropods, raising the question as to what survival or reproductive disadvantages they confer. Recent interest in using them in therapy lends a biomedical dimension to this question. Methods: Here, we examined the impact of the expression of Ciona intestinalis alternative oxidase, AOX, on the reproductive success of Drosophila melanogaster males. Sperm-competition assays were performed between flies carrying three copies of a ubiquitously expressed AOX construct, driven by the a-tubulin promoter, and wild-type males of the same genetic background. Results: In sperm-competition assays, AOX conferred a substantial disadvantage, associated with decreased production of mature sperm. Sperm differentiation appeared to proceed until the last stages, but was spatially deranged, with spermatozoids retained in the testis instead of being released to the seminal vesicle. High AOX expression was detected in the outermost cell-layer of the testis sheath, which we hypothesize may disrupt a signal required for sperm maturation. Conclusions: AOX expression in Drosophila thus has effects that are deleterious to male reproductive function. Our results imply that AOX therapy must be developed with caution.Peer reviewe

    Immobilisation of cocoa aspartic endoprotease

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    Expression of Ciona intestinalis AOX causes male reproductive defects in Drosophila melanogaster

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    Background: Mitochondrial alternative respiratory-chain enzymes are phylogenetically widespread, and buffer stresses affecting oxidative phosphorylation in species that possess them. However, they have been lost in the evolutionary lineages leading to vertebrates and arthropods, raising the question as to what survival or reproductive disadvantages they confer. Recent interest in using them in therapy lends a biomedical dimension to this question. Methods: Here, we examined the impact of the expression of Ciona intestinalis alternative oxidase, AOX, on the reproductive success of Drosophila melanogaster males. Sperm-competition assays were performed between flies carrying three copies of a ubiquitously expressed AOX construct, driven by the a-tubulin promoter, and wild-type males of the same genetic background. Results: In sperm-competition assays, AOX conferred a substantial disadvantage, associated with decreased production of mature sperm. Sperm differentiation appeared to proceed until the last stages, but was spatially deranged, with spermatozoids retained in the testis instead of being released to the seminal vesicle. High AOX expression was detected in the outermost cell-layer of the testis sheath, which we hypothesize may disrupt a signal required for sperm maturation. Conclusions: AOX expression in Drosophila thus has effects that are deleterious to male reproductive function. Our results imply that AOX therapy must be developed with caution.Peer reviewe

    Chaos in the one-dimensional gravitational three-body problem

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    We have investigated the appearance of chaos in the 1-dimensional Newtonian gravitational three-body system (three masses on a line with 1/r-1/r pairwise potential). We have concentrated in particular on how the behavior changes when the relative masses of the three bodies change (with negative total energy). For two mass choices we have calculated 18000 full orbits (with initial states on a 100×180100\times 180 lattice on the Poincar\'e section) and obtained dwell time distributions. For 105 mass choices we have calculated Poincar\'e maps for 10×1810\times 18 starting points. Our results show that the Poincar\'e section (and hence the phase space) divides into three well defined regions with orbits of different characteristics: 1) There is a region of fast scattering, with a minimum of pairwise collisions and smooth dependence on initial values. 2) In the chaotic scattering region the interaction times are longer, and both the interaction time and the final state depend sensitively on the starting point on the Poincar\'e section. For both 1) and 2) the initial and final states consists of a binary + single particle. 3) The third region consists of quasiperiodic orbits where the three masses are bound together forever. At the center of the quasiperiodic region there is the periodic Schubart orbit, whose stability turns out to correlate strongly with the global behavior.Comment: 24 pages of text (REVTEX 3.0) + 21 pages of figures. Figures are only available in paper form, ask for a preprint from the author

    Dynamic pathway of the photoinduced phase transition of TbMnO3_3

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    We investigate the demagnetization dynamics of the cycloidal and sinusoidal phases of multiferroic TbMnO3_3 by means of time-resolved resonant soft x-ray diffraction following excitation by an optical pump. Using orthogonal linear x-ray polarizations, we suceeded in disentangling the response of the multiferroic cycloidal spin order from the sinusoidal antiferromagnetic order in the time domain. This enables us to identify the transient magnetic phase created by intense photoexcitation of the electrons and subsequent heating of the spin system on a picosecond timescale. The transient phase is shown to be a spin density wave, as in the adiabatic case, which nevertheless retains the wave vector of the cycloidal long range order. Two different pump photon energies, 1.55 eV and 3.1 eV, lead to population of the conduction band predominantly via intersite dd-dd transitions or intrasite pp-dd transitions, respectively. We find that the nature of the optical excitation does not play an important role in determining the dynamics of magnetic order melting. Further, we observe that the orbital reconstruction, which is induced by the spin ordering, disappears on a timescale comparable to that of the cycloidal order, attesting to a direct coupling between magnetic and orbital orders. Our observations are discussed in the context of recent theoretical models of demagnetization dynamics in strongly correlated systems, revealing the potential of this type of measurement as a benchmark for such complex theoretical studies

    Algebraic Comparison of Partial Lists in Bioinformatics

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    The outcome of a functional genomics pipeline is usually a partial list of genomic features, ranked by their relevance in modelling biological phenotype in terms of a classification or regression model. Due to resampling protocols or just within a meta-analysis comparison, instead of one list it is often the case that sets of alternative feature lists (possibly of different lengths) are obtained. Here we introduce a method, based on the algebraic theory of symmetric groups, for studying the variability between lists ("list stability") in the case of lists of unequal length. We provide algorithms evaluating stability for lists embedded in the full feature set or just limited to the features occurring in the partial lists. The method is demonstrated first on synthetic data in a gene filtering task and then for finding gene profiles on a recent prostate cancer dataset
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