Perancangan Interior Elderly Day Care Center Sebagai Pusat Aktivitas Manula Di Surabaya

Modern human life in metropolitan cities of Surabaya Indonesia claimed to have high job mobility. Elderly man as one of the families who already do not have the ability to work will be home more often and be more neglected. The nursing home as a place of social services intended specifically for treating human age is not able to accommodate all the displaced seniors. This has resulted in the emergence of the idea of making an Elderly Day Care Center devoted to accomodate seniors with activities with attention to standard-satndar ekletik design and concept that is mixing between the modern and pop style to the homey ambience, fresh, and comfortable in order to support the activity of seniors in it

Karakteristik pada Balita Diare dengan Infeksi Enteropathogenic Escherichia Coli (Epec) di Puskesmas Rawat Inap Kota Pekanbaru

Diarrheal diseases remain one of the leading cause of childhood morbidity and mortality in most developing countries, with Enteropathogenic Escherichia coli (EPEC) being one of the most important aetiologic agents of children under-five years diarrhea in many of these countries. In Indonesia especially Pekanbaru, the epidemiology of these EPEC have not been well studied. During the period from April 2014 to September 2014, 47 stool sample were collected from children under-five years with acute diarrhea in the hospitality primary health care in Pekanbaru and the examination has been done in Microbiology Laboratory of Medical Faculty Riau University. The Escherichia coli were isolated and diagnosed by standard microbiological methods. The isolates confirmed to be Esherichia coli were subjected to a slide agglutination test with Escherichia coli polyvalent antisera. This study was a descriptive study using a consecutive sampling method to describe the characterization of Enteropathogenic Escherichia coli (EPEC) infection on children under-five years at the hospitality primary health care in Pekanbaru. Based on gender and age from all specimens that were collected, the diarrhea mostly found in male (59.5%), and in 12-59 months patients (93.6%). Out of the 47 stool samples, 1 isolate (2.2%) were positive for EPEC. The isolate was recovered from the 19 months female

Sustaining Educational Reforms in Introductory Physics

While it is well known which curricular practices can improve student performance on measures of conceptual understanding, the sustaining of these practices and the role of faculty members in implementing these practices are less well understood. We present a study of the hand-off of Tutorials in Introductory Physics from initial adopters to other instructors at the University of Colorado, including traditional faculty not involved in physics education research. The study examines the impact of implementation of Tutorials on student conceptual learning across eight first-semester, and seven second-semester courses, for fifteen faculty over twelve semesters, and includes roughly 4000 students. It is possible to demonstrate consistently high, and statistically indistinguishable, student learning gains for different faculty members; however, such results are not the norm, and appear to rely on a variety of factors. Student performance varies by faculty background - faculty involved in, or informed by physics education research, consistently post higher student learning gains than less-informed faculty. Student performance in these courses also varies by curricula used - all semesters in which the research-based Tutorials and Learning Assistants are used have higher student learning gains than those semesters that rely on non-research based materials and do not employ Learning Assistants.Comment: 21 pages, 4 figures, and other essential inf

“The Ganers” Kapal Pembersih Sampah dengan Sistem Lambung Tiga sebagai Solusi Pembersih Sampah di Teluk Jakarta

Jakarta bay is a bay in Laut Jawa located in north of DKI Jakarta province. Jakarta bay is one of dirtiest place in the world. To overcome that problem, this study designed “The Ganers (The Garbage Cleaner Ship)”. There is innovation technology of water garbage cleaner which is effective, innovative, and applicative in effort to increase marine potency in Jakarta bay. The Ganers take principle of Trimaran ship (three sides ship) that equipped by many specification of machine. Tools which is will be paired to that ship used to facilitate to run process cleaning the water garbage

Abundance of Ordo Lepidoptera in The Land Conversion of Ciwidey Pine Forest

The study entitled "Abundance of Ordo Lepidoptera in The Land Conversion of Ciwidey Pine Forest" aims to obtain the information about the abundance of insects of the ordo Lepidoptera and the influence of climatic factors on the abundance. The research method used is descriptive method, the research design is belt transect, and the sampling techniques used are pitfall trap, hand sorting, beating tray, and insect net. There are 6 stations with 5 quadrants in each. The results of this study obtained 37 individuals from 10 species, 10 genus, and 6 families. Abundance at station one is worth of 2 individuals/m2, abundance at station two is worth of 4 individuals/m2, abundance at station three is worth of 6 individuals/m2, abundance at station four is worth of 6 individuals/m2, abundance at station five is worth of 2 individuals/m2, abundance at station six worth of 10 individuals/m2

Sub-Lethal Concentrations of Graphene Oxide Trigger Acute-Phase Response and Impairment of Phase-I Xenobiotic Metabolism in Upcyte® Hepatocytes

The impact of graphene oxide on hepatic functional cells represents a crucial evaluation step for its potential application in nanomedicine. Primary human hepatocytes are the gold standard for studying drug toxicity and metabolism; however, current technical limitations may slow down the large-scale diffusion of this cellular tool for in vitro investigations. To assess the potential hepatotoxicity of graphene oxide, we propose an alternative cell model, the second-generation upcyte® hepatocytes, which show metabolic and functional profiles akin to primary human hepatocytes. Cells were acutely exposed to sub-lethal concentrations of graphene oxide (≤80 μg/ml) for 24 h and stress-related cell responses (such as apoptosis, oxidative stress, and inflammatory response) were evaluated, along with a broad investigation of graphene oxide impact on specialized hepatic functions. Results show a mild activation of early apoptosis but not oxidative stress or inflammatory response in our cell model. Notably, while graphene oxide clearly impacted phase-I drug-metabolism enzymes (e.g., CYP3A4, CYP2C9) through the inhibition of gene expression and metabolic activity, conversely, no effect was observed for phase-II enzyme GST and phase-III efflux transporter ABCG2. The GO-induced impairment of CYP3A4 occurs concomitantly with the activation of an early acute-phase response, characterized by altered levels of gene expression and protein production of relevant acute-phase proteins (i.e., CRP, Albumin, TFR, TTR). These data suggest that graphene oxide induces an acute phase response, which is in line with recent in vivo findings. In conclusion, upcyte® hepatocytes appear a reliable in vitro model for assessing nanomaterial-induced hepatotoxicity, specifically showing that sub-lethal doses of graphene oxide have a negative impact on the specialized hepatic functions of these cells. The impairment of the cytochrome P450 system, along with the activation of an acute-phase response, may suggest potential detrimental consequences for human health, as altered detoxification from xenobiotics and drugs

Physical assessment of toxicology at nanoscale: nano dose-metrics and toxicity factor

In this work, we propose a systematic and reproducible evaluation of nanoparticles (NPs) toxicology in living systems, based on a physical assessment and quantification of the toxic effects of NPs by the experimental determination of the key parameter affecting the toxicity outcome (i.e., the number of NPs) and of the NPs "toxicity factor". Such a strategy was applied to a well determined scenario, i.e., the ingestion of citrate-capped gold NPs (AuNPs) of different sizes by the model system Drosophila melanogaster. Using these AuNPs as a reference toxicity standard, we were able to define different regions in the multiparametric space of toxicity, enabling the classification of the toxic levels of other nanomaterials, such as quantum dots and pegylated AuNPs. This approach may pave the way to a systematic classification of nanomaterials, leading to important developments in risk assessment and regulatory approval, as well as in a wide range of nanomedicine applications

Malikhaing Kamay: The Effects of Social Media Marketing on Sales Performance of Micro, Small, and Medium Enterprises (MSME) within the Creatives Industry of Metro Manila

The study primarily tackled the effects of Social Media marketing on the sales performance of MSMEs in the Creatives Industry, specifically in Customer Feedback, Communication, Content Sharing, and Customer\u27s Relationship, through their individual and overall effects as factors under SMM. The study utilized qualitative methods to examine data from a survey of Creatives Industry MSME owners employed or residing in Metro Manila. After gathering adequate data for analysis, it was discovered that the Social Media Marketing factors Customer Feedback, Communication, Content Sharing, and Customer’s Relationships altogether affect the Sales Performance of Micro, Small, and Medium Enterprises within the Creatives Industry. But as individual variables, only Communication, Content Sharing, and Customers Relationships positively affect the Sales Performance of the MSMEs within the Creatives Industry. In contrast, Customer Feedback is not found to affect the Sales Performance of the MSMEs within the Creatives Industry. The researchers recommend that more businesses utilize social media to amass customers locally or worldwide. Through this, the country may continue to perceive the creative industry in a positive light while contributing to the country\u27s growing economy. For future researchers who seek to expound on the topic, the researchers suggest diving into the customer\u27s perspective and behavior rather than business owners. Future researchers may also expand on demographic effects or explore the topic in up-and-coming industries

Malikhaing Kamay: The Effects of Social Media Marketing on Sales Performance of Micro, Small, and Medium Enterprises (MSME) within the Creatives Industry of Metro Manila

The study primarily tackled the effects of Social Media marketing on the sales performance of MSMEs in the Creatives Industry, specifically in Customer Feedback, Communication, Content Sharing, and Customer\u27s Relationship, through their individual and overall effects as factors under SMM. The study utilized qualitative methods to examine data from a survey of Creatives Industry MSME owners employed or residing in Metro Manila. After gathering adequate data for analysis, it was discovered that the Social Media Marketing factors Customer Feedback, Communication, Content Sharing, and Customer’s Relationships altogether affect the Sales Performance of Micro, Small, and Medium Enterprises within the Creatives Industry. But as individual variables, only Communication, Content Sharing, and Customers Relationships positively affect the Sales Performance of the MSMEs within the Creatives Industry. In contrast, Customer Feedback is not found to affect the Sales Performance of the MSMEs within the Creatives Industry. The researchers recommend that more businesses utilize social media to amass customers locally or worldwide. Through this, the country may continue to perceive the creative industry in a positive light while contributing to the country\u27s growing economy. For future researchers who seek to expound on the topic, the researchers suggest diving into the customer\u27s perspective and behavior rather than business owners. Future researchers may also expand on demographic effects or explore the topic in up-and-coming industries

The Significance of Xylem Structure and Its Chemical Components in Certain Olive Tree Genotypes with Tolerance to Xylella fastidiosa Infection

Olive quick decline syndrome (OQDS) is a devastating plant disease caused by the bacterium Xylella fastidiosa (Xf). Exploratory missions in the Salento area led to the identification of putatively Xf-resistant olive trees (putatively resistant plants, PRPs) which were pauci-symptomatic or asymptomatic infected plants belonging to different genetic clusters in orchards severely affected by OQDS. To investigate the defense strategies employed by these PRPs to contrast Xf infection, the PRPs were analyzed for the anatomy and histology of xylem vessels, patterns of Xf distribution in host tissues (by the fluorescent in situ hybridization technique—FISH) and the presence of secondary metabolites in stems. The xylem vessels of the PRPs have an average diameter significantly lower than that of susceptible plants for each annual tree ring studied. The histochemical staining of xylem vessels highlighted an increase in the lignin in the parenchyma cells of the medullary rays of the wood. The 3D images obtained from FISH-LSM (laser scanning microscope) revealed that, in the PRPs, Xf cells mostly appeared as individual cells or as small aggregates; in addition, these bacterial cells looked to be incorporated in the autofluorescence signal of gels and phenolic compounds regardless of hosts’ genotypes. In fact, the metabolomic data from asymptomatic PRP stems showed a significant increase in compounds like salicylic acid, known as a signal molecule which mediates host responses upon pathogen infection, and luteolin, a naturally derived flavonoid compound with antibacterial properties and with well-known anti-biofilm effects. Findings indicate that the xylem vessel geometry together with structural and chemical defenses are among the mechanisms operating to control Xf infection and may represent a common resistance trait among different olive genotypes