409 research outputs found
Dynamic capabilities to match multiple product generations and market rhythm
Purpose : The purpose of this paper is to provide greater insights to managers seeking to time properly the launches of innovative new products (NPs) across multiple generations. This paper aims to address the rhythm matching problem by developing a typology and a conceptual framework of the interaction between a firm’s technological readiness to launch NPs and a market’s receptivity in influencing a firm’s long-term performance. Design/methodology/approach –:Based on the new product development (NPD) and diffusion of innovation literatures, the paper develops a model explicitly to address the rhythm matching problem by highlighting the interaction between a firm’s technological readiness to launch new products and a market’s receptivity in influencing a firm’s long-term performance. The logic of this model may be described as follows: long-term performance is a function of matching: products to customer needs, marketingmix dynamics to customer segments and buying behavior dynamics, and logistics, supply chain management, and inventory to market dynamics and financial efficiency; uncertainty in: knowledge of needs, market segments and their dynamics, and market dynamics is all a function of time, as is financial efficiency. Therefore, a firm’s long-term performance is a function of these matches over time. Findings : Deriving from the proposed model and typology, it was found that in independent rhythm windows, the management focus is on a single generation and each successive generation can be planned independently. In market- imposed windows, firms aim at adapting their own NP readiness rhythm to the market receptivity rhythm. In firm-imposed windows, firms have the initiative to drive the market receptivity rhythm. In dynamically resultant windows, everything is more complicated because firms’ NP readiness rhythm and market receptivity rhythm influence each other. Originality/value : The model and typology developed in this paper are a breakthrough result of synthesizing various traditions of NPD and diffusion of innovation research. It is believed that the paper provides a rich conceptual framework drawing together extant research on the development and introduction of new products. The framework is intended both to explicitly inform managers of the importance of rhythm matching as well as to the factors that influence such matching. It is also intended to provide a lens with which further research can be directed to increase the efficiency and effectiveness of resource utilization in NPD and the long- term success of the firms
A framework for innovative service design
Drawing on research from design science, marketing and service science, our paper provides an integrated framework for evaluating and directing innovative service design. The main goal of our review is to highlight the strengths of existing frameworks and to suggest how they can be enhanced in combination with design science principles. Based on our review, we propose a new framework for the design of innovative services that integrates several key paradigmatic approaches and identifies fundamental open research questions. Our approach is unique as it combines three service disciplines, namely services marketing, service science, and design science, and provides a new framework that describes step by step the procedure that needs to be taken and the conditions that need to be met for developing innovative services. We believe that providing such a framework is a valuable addition to the literature
Effect of stage of harvest on the quality of cardamom (Elettaria cardamomum Maton)
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Effect of stage of harvest on the quality of cardamom (Elettaria cardamomum Maton)
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Role Of Self Help Groups In Promoting Rural Entrepreneurship For Strengthening Aatma Nirbhar Bharat
The corona-19 pandemic has pervaded into every nook & corner of the world. Since the entire globe has announced lockdown for uncertain period, the commercial activity has pushed the indicators of economic health in a state of depression. A multi-centered approach is the need of the hour to take the economy out of this crisis. In India on May 12th, the Prime Minister, Mr. Narendra Modi, announced a special economic package of Rs 20 lakh crore with the aim of making the country independent against the tough competition in the global supply chain and to help in empowering the people who have been adversely affected by COVID. In order to achieve this vision, India needs to focus on holistic and sustainable development. The formation of SHGs is a holistic program with an objective to bring the rural entrepreneurs in a platform and encourage them to initiate innovation. This research paper makes an attempt to study the potentialities of Self Help Group ( SHGs) in strengthening economy of India to support Atma Nirbhar Bharat Abhiyan
CUSTOMER SATISFACTION TOWARDS HOSPITALS A STUDY ON SELECTED HOSPITALS AT SHIVAMOGGA CITY
CUSTOMER SATISFACTION TOWARDS HOSPITALS A STUDY ON SELECTED HOSPITALS AT SHIVAMOGGA CITY The opening of Indian economy since 1991 has given a new dimension to the economic structure of the country. The service sector is contributing more than 50% to the GDP. In service sector the contribution of healthcare sector towards GDP is significant. India will spend a huge         Rs 200,000 crore on healthcare in the next five years as the country witnessing changes in its demographic profile accompanied with lifestyle diseases and increasing medical expenses. Nearly 80 per cent of the required investment is coming from the private sector. The government spending on healthcare is around 0.9 per cent of the total GDP, which limits the extent and effectiveness of the coverage it can provide. Private healthcare will continue to be the largest component in 2012 and is likely to double to   Rs 156,000 crore. Therefore the study focuses on services provided by private hospitals.  Â
EVALUATION OF BIOACTIVITY OF JAGGERY PREPARED USING PLANT MUCILAGE AS CLARIFICANT
Objective: The aim of the study was to prepare the jaggery using plant mucilage as clarificants and to evaluate the bioactivity of jaggery by determining total phenols, total flavonoids, reducing power, antibacterial activity, and antihelmintic activity.Methods: Jaggery was prepared from sugarcane variety Co-80632 using five plant mucilage as clarificants, namely Aloe vera, flax seeds, fenugreek, purslane, and malabar spinach at three different concentrations, i.e., 0.1%, 0.2%, and 0.4% of raw sugarcane juice. The characteristic bioactivities such as total phenol content by Folin–Ciocalteu method, flavonoids content by spectrophotometer method, reducing power assay by measuring the absorbance at 700 nm, antibacterial activity by well-diffusion method, and antihelmintic activity by in vitro were determined.Results: The highest total phenolic content was observed in jaggery prepared using plant mucilage clarificant of A. vera (JAV4 [3.68±0.02]) and Fenugreek seeds (JFG4 [3.61±0.02]) at 0.4% followed by them at 0.2% and 0.1% concentration, respectively. Similarly, a significant amount of total flavonoids content was elevated only in 0.4% plant mucilage clarificants of Aloe vera-treated experimental group jaggery (0.73±0.01) compared to control (0.61±0.02). Further, the antioxidant activity of jaggery was evaluated by reducing power. The increased absorbance at 700 nm indicated the presence of reducing power. At 10 mg/ml concentration, an absorbance unit of 1.93 and 1.80 was observed for jaggery prepared using 0.4% concentration of A. vera and fenugreek seed mucilage clarificants. Antihelmintic activity of jaggery showed dosage depended on the pattern where with the increase in the concentration of mucilage, the antihelmintic activity enhanced. A. vera mucilage showed maximum antihelmintic activity at 0.4% concentration with paralytic time (28.6 min) and death time (39.6 min).Conclusion: Jaggery prepared using plants mucilaginous clarificants is the richest source of polyphenols such as phenolic acids and flavonoids, thereby contributed to the enhancement of bioactivity such as antioxidant, antibacterial, and antihelmintic activity. Thus, jaggery prepared using plant mucilage as clarificants is a novel nutraceutical product which can supplement the nutrients along with various medicinal properties through antioxidant, antibacterial, and antihelmintic activity
Evaluation and in Vivo Anti-Cancer Property of Methanol Extract of Acrostichum Aureum L and Insilco Toxicity Prediction
This study is to evaluate the in vivo anti-cancer property of methanol extract of Acrostichum aureum L. against Dalton’s Lymphoma Ascites (DLA) murine models. Is done by Preparation of methanol extract of Acrostichum aureum L. leaves using cold extraction method and it is Determined by in vivo anti-tumour activity of methanol extract of Acrostichum aureum (MEAA) by administering MEAA in DLA-induced ascites-bearing animals, to know the progression of the tumour the Evaluation of tumour progression in MEAA treated ascites tumour-bearing animals is carried out and haematological parameters of MEAA treated ascites tumour-bearing animals shows maximum effectiveness , Finally evaluation is done by MEAA treated tumour bearing animals. Analgesic and antioxidant activity of extracts from this species. Ethanolic extracts of A. aureum showed anti-fertility activity in rats as per the report of Dhar et al., in 1992. The cytotoxic effect of water and methanol extracts from a Bangladeshi specimen of A.aureum on gastric, colon and breast cancer cells were studied by Uddin et al., 2010. The anti-inflammatory activity of ethanolic (95%) crude extract of the roots of A. aureum was reported in varied carrageenan-induced inflammation rat models by Hossain et al., in 2011. Ethanol extract of A. aureum possesses analgesic activity and in vitro antioxidant activity which was found to be significantly effective in scavenging DPPH (EC50 =41.95μg/ml)
No evidence for association between SLC11A1 and visceral leishmaniasis in India.
BACKGROUND: SLC11A1 has pleiotropic effects on macrophage function and remains a strong candidate for infectious disease susceptibility. 5' and/or 3' polymorphisms have been associated with tuberculosis, leprosy, and visceral leishmaniasis (VL). Most studies undertaken to date were under-powered, and none has been replicated within a population. Association with tuberculosis has replicated variably across populations. Here we investigate SLC11A1 and VL in India. METHODS: Nine polymorphisms (rs34448891, rs7573065, rs2276631, rs3731865, rs17221959, rs2279015, rs17235409, rs17235416, rs17229009) that tag linkage disequilibrium blocks across SLC11A1 were genotyped in primary family-based (313 cases; 176 families) and replication (941 cases; 992 controls) samples. Family- and population-based analyses were performed to look for association between SLC11A1 variants and VL. Quantitative RT/PCR was used to compare SLC11A1 expression in mRNA from paired splenic aspirates taken before and after treatment from 24 VL patients carrying different genotypes at the functional promoter GTn polymorphism (rs34448891). RESULTS: No associations were observed between VL and polymorphisms at SLC11A1 that were either robust to correction for multiple testing or replicated across primary and replication samples. No differences in expression of SLC11A1 were observed when comparing pre- and post-treatment samples, or between individuals carrying different genotypes at the GTn repeat. CONCLUSIONS: This is the first well-powered study of SLC11A1 as a candidate for VL, which we conclude does not have a major role in regulating VL susceptibility in India.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are
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