Poplar Forests of the Charysh, Biya and Katun Rivers, Altai Territory, Russia

На основе классификации растительности методом Браун-Бланке охарактеризованы тополевые (Populus laurifolia, Populus nigra) леса Чарыша, Бии и Катуни, распространенные в местах выхода этих рек с Алтайских гор на Предалтайскую равнину. Топольники среднего Чарыша, известные как ассоциация Populetum laurifolio-nigrae Taran (1997)2015, обследованы у сел Трусово (51°42'30'' с. ш., 82°29'10'' в. д.) и Озерки (51°48'07'' с. ш., 82°24'18'' в. д.), топольники нижней Бии (асс. Viburno opuli-Populetum laurifoliae Taran 1997) – у с. Стан-Бехтемир (52°36'40'' с. ш., 85°39'00'' в. д.), топольники нижней Катуни (субассоциация Equiseto hyemalis-Populetum nigrae violetosum irinae Taran 1997) – у с. Талица (52°23'36'' с. ш., 85°40'30'' в. д.). Детально охарактеризованы видовой состав, фитоценотическая структура и условия произрастания этих лесов. Дан обзор литературы по лесам c доминированием Populus laurifolia. Тополевые (Populus laurifolia, P. nigra) леса горных притоков Оби образуют союз Populion laurifolio-nigrae Taran 2015 (Salicetalia purpureae Moor 1958, Salicetea purpureae Moor 1958). Ареал союза – горные и предгорные отрезки речных пойм, пересекающих северный и западный макросклоны Алтайских гор, а также верхнее течение р. ТомиOn a base of Braun-Blanquet vegetation classification, natural poplar (Populus laurifolia, Populus nigra) forests of the Charysh, Biya and Katun Rivers are defined. The forests are located in areas where the rivers exit from the Altai Mountains to Prealtai plain. The middle Charysh poplar forests known as association Populetum laurifolio-nigrae Taran (1997)2015 were studied near Trusovo (51°42'30'' N, 82°29'10'' E) and Ozerki (51°48'07'' N, 82°24'18'' E) villages, the lower Biya ones (ass. Viburno opuli-Populetum laurifoliae Taran 1997) were studied near Stan-Bekhtemir village (52°36'40'' N, 85°39'00'' E), the lower Katun ones (subass. Equiseto hyemalis-Populetum nigrae violetosum irinae Taran 1997) were studied near Talitsa village (52°23'36'' N, 85°40'30'' E). The forests species composition, phytocenotic structure, and habitat conditions are detailed defined. The review of the literature about forests dominated by Populus laurifolia is given. Poplar (Populus laurifolia, P. nigra) forests of the Ob River mountain tributaries form alliance Populion laurifolio-nigrae Taran 2015 (Salicetalia purpureae Moor 1958, Salicetea purpureae Moor 1958). The alliance areal envelopes mountain and piedmont reaches of river floodplains located on the north and west macroslopes of the Altai Mountains and also the Tom River upper cours

Anti-corrosion ceramic coatings on the surface of Nd-Fe-B repelling magnets

The results of vacuum-arc deposition of thin ZrO₂coatings to protect the surface of Nd-Fe-B permanent magnets used as repelling devices in orthodontics are presented. The structure, phase composition and mechanical properties of zirconium dioxide films have been investigated by means of SEM, XRD, EDX, XRF and nanoindentation method. It was revealed the formation of polycrystalline ZrO₂ films of monoclinic modification with average grain size 25 nm. The influence of the ZrO₂ coating in terms of its barrier properties for corrosion in quasi-physiological 0.9 NaCl solution has been studied. Electrochemical measurements indicated good barrier properties of the coating on specimens in the physiological solution environment

Synthesis and characterisation of nanocrystalline ZrN PVD coatings on AISI 430 stainless steel

The nanocrystalline films of zirconium nitride have been synthesized using ion-plasma vacuum-arc deposition technique in combination with high-frequency discharge (RF) on AISI 430 stainless steel at 150oC. Structure examinations X-ray fluorescent analysis (XRF), X-ray diffraction analysis (XRD), scanning electron microscopy (SEM) with microanalysis (EDS), and transmission electron microscopy (TEM), nanoidentation method – were performed to study phase and chemical composition, surface morphology, microstructure and nanohardness of coatings. The developed technology provided low-temperature coatings synthesis, minimized discharge breakdown decreasing formation of macroparticles (MPs) and allowed to deposit ZrN coatings with hardness variation 26.6…31.5 GPa. It was revealed that ZrN single-phase coatings of cubic modification with finecrystalline grains of 20 nm in size were formed

Simultaneous Determination of Nitrite and Nitrate in Milk Samples by Ion Chromatography Method and Estimation of Dietary Intake

The presence of nitrate and nitrite in foods may be considered hazardous after ingestion in the gastrointestinal tract due to their reaction with naturally occurred secondary amines to form potentially carcinogenic nitrosamines. Due to this fact, a new method was developed in this study for the simultaneous determination of nitrite and nitrate in milk samples using by ion chromatography. Proposed mobile phase composed of sodium hydrogen carbonate and sodium carbonate (1.0 and 3.2 mmol/L) with a flow rate of 0.7 ml/min. The average recoveries for nitrate and nitrite were higher than 86 and 88, respectively. The limit of detection for nitrate and nitrite were 0.24 and 0.09 mg/L, respectively. The results of 102 real milk samples showed nitrate was found in all of the samples (100) with a mean of 34 ± 11 mg/L, while nitrite was found in none of the samples. The mean intake of nitrate in all age groups was lower than World Health Organization guideline. The present assessment concludes that the maximum contaminant level was equal to 82.8 mg/L nitrate. This method was fast, sensitive and accurate and is capable of being an alternative method in food control laboratories for investigation of nitrite and nitrate content. This is the first study of the determination and survey of nitrite and nitrate and exposure assessment of the Iranian population to nitrite and nitrate level in milk, which was widely used in infants and adolescents as one of the basic food components. Copyright © Taylor & Francis Group, LLC

Incidence and time course of everolimus-related adverse events in postmenopausal women with hormone receptor-positive advanced breast cancer: insights from BOLERO-2.

BackgroundIn the BOLERO-2 trial, everolimus (EVE), an inhibitor of mammalian target of rapamycin, demonstrated significant clinical benefit with an acceptable safety profile when administered with exemestane (EXE) in postmenopausal women with hormone receptor-positive (HR(+)) advanced breast cancer. We report on the incidence, time course, severity, and resolution of treatment-emergent adverse events (AEs) as well as incidence of dose modifications during the extended follow-up of this study.Patients and methodsPatients were randomized (2:1) to receive EVE 10 mg/day or placebo (PBO), with open-label EXE 25 mg/day (n = 724). The primary end point was progression-free survival. Secondary end points included overall survival, objective response rate, and safety. Safety evaluations included recording of AEs, laboratory values, dose interruptions/adjustments, and study drug discontinuations.ResultsThe safety population comprised 720 patients (EVE + EXE, 482; PBO + EXE, 238). The median follow-up was 18 months. Class-effect toxicities, including stomatitis, pneumonitis, and hyperglycemia, were generally of mild or moderate severity and occurred relatively early after treatment initiation (except pneumonitis); incidence tapered off thereafter. EVE dose reduction and interruption (360 and 705 events, respectively) required for AE management were independent of patient age. The median duration of dose interruption was 7 days. Discontinuation of both study drugs because of AEs was higher with EVE + EXE (9%) versus PBO + EXE (3%).ConclusionsMost EVE-associated AEs occur soon after initiation of therapy, are typically of mild or moderate severity, and are generally manageable with dose reduction and interruption. Discontinuation due to toxicity was uncommon. Understanding the time course of class-effect AEs will help inform preventive and monitoring strategies as well as patient education.Trial registration numberNCT00863655

Розроблення конструкцій буферних гумових футеровок барабанних і трубних млинів та результати випробування моделей

Розкриті переваги й недоліки буферних гумових футеровок, наведені результати випробування футерувальних плит традиційної конструкції та моделей футерівки буферної конструкці