10,028 research outputs found
Solving Tree Problems with Category Theory
Artificial Intelligence (AI) has long pursued models, theories, and
techniques to imbue machines with human-like general intelligence. Yet even the
currently predominant data-driven approaches in AI seem to be lacking humans'
unique ability to solve wide ranges of problems. This situation begs the
question of the existence of principles that underlie general problem-solving
capabilities. We approach this question through the mathematical formulation of
analogies across different problems and solutions. We focus in particular on
problems that could be represented as tree-like structures. Most importantly,
we adopt a category-theoretic approach in formalising tree problems as
categories, and in proving the existence of equivalences across apparently
unrelated problem domains. We prove the existence of a functor between the
category of tree problems and the category of solutions. We also provide a
weaker version of the functor by quantifying equivalences of problem categories
using a metric on tree problems.Comment: 10 pages, 4 figures, International Conference on Artificial General
Intelligence (AGI) 201
Fantasies of subjugation: a discourse theoretical account of British policy on the European Union
The decision by the UK government to hold a referendum on Britain’s membership of the European Union (EU) marks an important development in policy towards the EU. Policy changes of this kind must be understood in the historical and political context in which they occur. This includes the framing of the policy issues within public discourse. In the UK, policies are formed in a discursive environment which is overwhelmingly hostile towards the EU. Debates are structured by a predominantly Euroskeptic discourse which emphasizes the UK’s separation and heterogeneity from the rest of the EU. Drawing on the logics of critical explanation, this article examines the structure and affective power of Euroskeptic discourses which dictate the terms of the EU debate. It presents a case study of the recent EU treaty revision process, culminating in the Treaty of Lisbon. In so doing, it enables a deeper understanding of recent policy developments
The Gattini cameras for optical sky brightness measurements at Dome C, Antarctica
The Gattini cameras are two site testing instruments for
the measurement of optical sky brightness, large area cloud cover and auroral detection of the night sky above the high altitude Dome C site in Antarctica. The cameras have been operating since installation in January 2006 and are currently at the end of the first Antarctic winter season. The cameras are transit in nature and are virtually identical both adopting Apogee Alta CCD detectors. By taking frequent images of the night sky we obtain long term cloud cover statistics, measure the sky background intensity as a function of solar and lunar altitude and
phase and directly measure the spatial extent of bright aurora if present and when they occur. The full data set will return in December 2006 however a limited amount of data has been transferred via the Iridium network enabling preliminary data reduction and system evaluation.
An update of the project is presented together with preliminary results from data taken since commencement of the winter season
Reconciling Semiclassical and Bohmian Mechanics: III. Scattering states for continuous potentials
In a previous paper [J. Chem. Phys. 121 4501 (2004)] a unique bipolar
decomposition, Psi = Psi1 + Psi2 was presented for stationary bound states Psi
of the one-dimensional Schroedinger equation, such that the components Psi1 and
Psi2 approach their semiclassical WKB analogs in the large action limit. The
corresponding bipolar quantum trajectories, as defined in the usual Bohmian
mechanical formulation, are classical-like and well-behaved, even when Psi has
many nodes, or is wildly oscillatory. A modification for discontinuous
potential stationary stattering states was presented in a second paper [J.
Chem. Phys. 124 034115 (2006)], whose generalization for continuous potentials
is given here. The result is an exact quantum scattering methodology using
classical trajectories. For additional convenience in handling the tunneling
case, a constant velocity trajectory version is also developed.Comment: 16 pages and 14 figure
Tenofovir disoproxil fumarate for prevention of HIV infection in women: a phase 2, double-blind, randomized, placebo-controlled trial.
ObjectivesThe objective of this trial was to investigate the safety and preliminary effectiveness of a daily dose of 300 mg of tenofovir disoproxil fumarate (TDF) versus placebo in preventing HIV infection in women.DesignThis was a phase 2, randomized, double-blind, placebo-controlled trial.SettingThe study was conducted between June 2004 and March 2006 in Tema, Ghana; Douala, Cameroon; and Ibadan, Nigeria.ParticipantsWe enrolled 936 HIV-negative women at high risk of HIV infection into this study.InterventionParticipants were randomized 1:1 to once daily use of 300 mg of TDF or placebo.Outcome measuresThe primary safety endpoints were grade 2 or higher serum creatinine elevations (>2.0 mg/dl) for renal function, grade 3 or 4 aspartate aminotransferase or alanine aminotransferase elevations (>170 U/l) for hepatic function, and grade 3 or 4 phosphorus abnormalities (<1.5 mg/dl). The effectiveness endpoint was infection with HIV-1 or HIV-2.ResultsStudy participants contributed 428 person-years of laboratory testing to the primary safety analysis. No significant differences emerged between treatment groups in clinical or laboratory safety outcomes. Study participants contributed 476 person-years of HIV testing to the primary effectiveness analysis, during which time eight seroconversions occurred. Two were diagnosed in participants randomized to TDF (0.86 per 100 person-years) and six in participants receiving placebo (2.48 per 100 person-years), yielding a rate ratio of 0.35 (95% confidence interval = 0.03-1.93), which did not achieve statistical significance. Owing to premature closures of the Cameroon and Nigeria study sites, the planned person-years of follow-up and study power could not be achieved.ConclusionDaily oral use of TDF in HIV-uninfected women was not associated with increased clinical or laboratory adverse events. Effectiveness could not be conclusively evaluated because of the small number of HIV infections observed during the study
Effect of Using the Same vs Different Order for Second Readings of Screening Mammograms on Rates of Breast Cancer Detection A Randomized Clinical Trial
Importance Interpreting screening mammograms is a difficult repetitive task that can result in missed cancers and false-positive recalls. In the United Kingdom, 2 film readers independently evaluate each mammogram to search for signs of cancer and examine digital mammograms in batches. However, a vigilance decrement (reduced detection rate with time on task) has been observed in similar settings.
Objective To determine the effect of changing the order for the second film reader of batches of screening mammograms on rates of breast cancer detection.
Design, Setting, and Participants A multicenter, double-blind, cluster randomized clinical trial conducted at 46 specialized breast screening centers from the National Health Service Breast Screening Program in England for 1 year (all between December 20, 2012, and November 3, 2014). Three hundred sixty readers participated (mean, 7.8 readers per center)—186 radiologists, 143 radiography advanced practitioners, and 31 breast clinicians, all fully qualified to report mammograms in the NHS breast screening program.
Interventions The 2 readers examined each batch of digital mammograms in the same order in the control group and in the opposite order to one another in the intervention group.
Main Outcomes and Measures The primary outcome was cancer detection rate; secondary outcomes were rates of recall and disagreements between readers.
Results Among 1 194 147 women (mean age, 59.3; SD, 7.49) who had screening mammograms (596 642 in the intervention group; 597 505 in the control group), the images were interpreted in 37 688 batches (median batch size, 35; interquartile range [IQR]; 16-46), with each reader interpreting a median of 176 batches (IQR, 96-278). After completion of all subsequent diagnostic tests, a total of 10 484 cases (0.88%) of breast cancer were detected. There was no significant difference in cancer detection rate with 5272 cancers (0.88%) detected in the intervention group vs 5212 cancers (0.87%) detected in the control group (difference, 0.01% points; 95% CI, −0.02% to 0.04% points; recall rate, 24 681 [4.14%] vs 24 894 [4.17%]; difference, −0.03% points; 95% CI, −0.10% to 0.04% points; or rate of reader disagreements, 20 471 [3.43%] vs 20 793 [3.48%]; difference, −0.05% points; 95% CI, −0.11% to 0.02% points).
Conclusions and Relevance Interpretation of batches of mammograms by qualified screening mammography readers using a different order vs the same order for the second reading resulted in no significant difference in rates of detection of breast cancer.
Trial Registration isrctn.org Identifier: ISRCTN4660337
Plasma Turbulence in the Local Bubble
Turbulence in the Local Bubble could play an important role in the
thermodynamics of the gas that is there. The best astronomical technique for
measuring turbulence in astrophysical plasmas is radio scintillation.
Measurements of the level of scattering to the nearby pulsar B0950+08 by
Philips and Clegg in 1992 showed a markedly lower value for the line-of-sight
averaged turbulent intensity parameter is smaller than normal for two of them, but is completely nominal for
the third. This inconclusive status of affairs could be improved by
measurements and analysis of ``arcs'' in ``secondary spectra'' of pulsars.Comment: Submitted to Space Science Reviews as contribution to Proceedings of
ISSI (International Space Science Institute) workshop "From the Heliosphere
to the Local Bubble". Refereed version accepted for publicatio
Kinematic Age Estimates for 4 Compact Symmetric Objects from the Pearson-Readhead Survey
Based on multi-epoch observations at 15 and 43 GHz with the Very Long
Baseline Array (VLBA) we detect significant angular expansions between the two
hot spots of 4 Compact Symmetric Objects (CSOs). From these relative motions we
derive kinematic ages of between 300 and 1200 years for the radio emission.
These ages lend support to the idea that CSOs are produced in a recent phase of
activity. These observations also allow us to study the evolution of the hot
spots dynamically in individual sources. In all 4 sources the hot spots are
separating along the source axis, but in 1031+567 the tip of one hot spot
appears to be moving almost orthogonally to the source axis. Jet components,
seen in 3 of the 4 sources observed, are found to be moving relativistically
outward from the central engines towards the more slowly moving hot spots.Comment: in press at ApJ for v. 541 Oct. 1, 2000, 23 page LaTeX document
includes 6 postscript figure
Absence of the Rashba effect in undoped asymmetric quantum wells
To an electron moving in free space an electric field appears as a magnetic
field which interacts with and can reorient the electron spin. In semiconductor
quantum wells this spin-orbit interaction seems to offer the possibility of
gate-voltage control in spintronic devices but, as the electrons are subject to
both ion-core and macroscopic structural potentials, this over-simple picture
has lead to intense debate. For example, an externally applied field acting on
the envelope of the electron wavefunction determined by the macroscopic
potential, underestimates the experimentally observed spin-orbit field by many
orders of magnitude while the Ehrenfest theorem suggests that it should
actually be zero. Here we challenge, both experimentally and theoretically, the
widely held belief that any inversion asymmetry of the macroscopic potential,
not only electric field, will produce a significant spin-orbit field for
electrons. This conclusion has far-reaching consequences for the design of
spintronic devices while illuminating important fundamental physics.Comment: 7 pages, 5 fig
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