57,620 research outputs found

    Entanglement Swapping: Entangling Atoms That Never Interacted

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    In this paper we discuss four different proposals of entangling atomic states of particles which have never interacted. The experimental realization proposed makes use of the interaction of Rydberg atoms with a micromaser cavity prepared in either a coherent state or in a superposition of the zero and one field Fock states. We consider atoms in either a three-level cascade or lambda configurationComment: 17 pages and 2 figure

    Adaptive primal-dual genetic algorithms in dynamic environments

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    This article is placed here with permission of IEEE - Copyright @ 2010 IEEERecently, there has been an increasing interest in applying genetic algorithms (GAs) in dynamic environments. Inspired by the complementary and dominance mechanisms in nature, a primal-dual GA (PDGA) has been proposed for dynamic optimization problems (DOPs). In this paper, an important operator in PDGA, i.e., the primal-dual mapping (PDM) scheme, is further investigated to improve the robustness and adaptability of PDGA in dynamic environments. In the improved scheme, two different probability-based PDM operators, where the mapping probability of each allele in the chromosome string is calculated through the statistical information of the distribution of alleles in the corresponding gene locus over the population, are effectively combined according to an adaptive Lamarckian learning mechanism. In addition, an adaptive dominant replacement scheme, which can probabilistically accept inferior chromosomes, is also introduced into the proposed algorithm to enhance the diversity level of the population. Experimental results on a series of dynamic problems generated from several stationary benchmark problems show that the proposed algorithm is a good optimizer for DOPs.This work was supported in part by the National Nature Science Foundation of China (NSFC) under Grant 70431003 and Grant 70671020, by the National Innovation Research Community Science Foundation of China under Grant 60521003, by the National Support Plan of China under Grant 2006BAH02A09, by the Engineering and Physical Sciences Research Council (EPSRC) of U.K. under Grant EP/E060722/1, and by the Hong Kong Polytechnic University Research Grants under Grant G-YH60

    Sub-Planck spots of Schroedinger cats and quantum decoherence

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    Heisenberg's principle1^1 states that the product of uncertainties of position and momentum should be no less than Planck's constant \hbar. This is usually taken to imply that phase space structures associated with sub-Planck (\ll \hbar) scales do not exist, or, at the very least, that they do not matter. I show that this deeply ingrained prejudice is false: Non-local "Schr\"odinger cat" states of quantum systems confined to phase space volume characterized by `the classical action' AA \gg \hbar develop spotty structure on scales corresponding to sub-Planck a=2/Aa = \hbar^2 / A \ll \hbar. Such structures arise especially quickly in quantum versions of classically chaotic systems (such as gases, modelled by chaotic scattering of molecules), that are driven into nonlocal Schr\"odinger cat -- like superpositions by the quantum manifestations of the exponential sensitivity to perturbations2^2. Most importantly, these sub-Planck scales are physically significant: aa determines sensitivity of a quantum system (or of a quantum environment) to perturbations. Therefore sub-Planck aa controls the effectiveness of decoherence and einselection caused by the environment38^{3-8}. It may also be relevant in setting limits on sensitivity of Schr\"odinger cats used as detectors.Comment: Published in Nature 412, 712-717 (2001

    Inverted polymer fullerene solar cells exceeding 10% efficiency with poly(2-ethyl-2-oxazoline) nanodots on electron-collecting buffer layers

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    Polymer solar cells have been spotlighted due to their potential for low-cost manufacturing but their efficiency is still less than required for commercial application as lightweight/flexible modules. Forming a dipole layer at the electron-collecting interface has been suggested as one of the more attractive approaches for efficiency enhancement. However, only a few dipole layer material types have been reported so far, including only one non-ionic (charge neutral) polymer. Here we show that a further neutral polymer, namely poly(2-ethyl-2-oxazoline) (PEOz) can be successfully used as a dipole layer. Inclusion of a PEOz layer, in particular with a nanodot morphology, increases the effective work function at the electron-collecting interface within inverted solar cells and thermal annealing of PEOz layer leads to a state-of-the-art 10.74% efficiency for single-stack bulk heterojunction blend structures comprising poly[4,8-bis(5-(2-ethylhexyl)thiophen-2-yl)benzo[1,2-b:4,5-b′]dithiophene-alt-3-fluorothieno[3,4-b]thiophene-2-carboxylate] as donor and [6,6]-phenyl-C71-butyric acid methyl ester as acceptor

    Endocervical glandular neoplasia associated with lobular endocervical glandular hyperplasia is HPV-independent and correlates with carbonic anhydrase-IX expression: a Gynaecological Oncology Group Study.

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    BackgroundLobular endocervical glandular hyperplasia (LEGH) is a rare lesion of the uterine cervix. It has been proposed that LEGH may represent a precursor lesion to a group of mucinous adenocarcinoma with gastric phenotype (GA) that is independent of high-risk human papillomavirus (H-HPV) infection. Carbonic anhydrase-IX (CA-IX) is highly expressed in conventional glandular lesions (CGLs). However, expression of CA-IX in LEGH or GA has not been studied.MethodsIn all, 12 CGLs, 7 LEGHs, 6 LEGHs with coexisting adenocarcinoma in situ (AIS, 3) and GA (3) were identified from Japanese women with a cytological diagnosis of atypical glandular cells of undetermined significance. Immunostaining was used to detect CA-IX and p16(INK)4(a) (hereafter termed p16) protein expression in the tissues and CA-IX protein expression in the Papanicolaou smears (PSs). Polymerase chain reaction was used to detect H-HPV DNA in liquid-based cytology.ResultsOut of 12 (83%) CGLs, 10 were positive with H-HPV and high levels of CA-IX expression were seen in all (100%) cases. P16 protein expression was observed in 11 out of 12 (92%) cases. None of the LEGHs, LEGHs with AIS or GA were positive for H-HPV and only 8 out of 13 (62%) showed focal weak (1+) p16 expression. In contrast, all cases (100%) exhibited strong CA-IX protein expression.ConclusionOur study suggests that there are different molecular mechanisms of carcinogenesis resulting in CGLs vs LEGHs associated with AIS or GA. There is also a possible link between LEGHs and GAs. Furthermore, CA-IX expression may serve as a useful biomarker for the detection of GAs in the absence of H-HPV infection

    Kinetic Analysis of Discrete Path Sampling Stationary Point Databases

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    Analysing stationary point databases to extract phenomenological rate constants can become time-consuming for systems with large potential energy barriers. In the present contribution we analyse several different approaches to this problem. First, we show how the original rate constant prescription within the discrete path sampling approach can be rewritten in terms of committor probabilities. Two alternative formulations are then derived in which the steady-state assumption for intervening minima is removed, providing both a more accurate kinetic analysis, and a measure of whether a two-state description is appropriate. The first approach involves running additional short kinetic Monte Carlo (KMC) trajectories, which are used to calculate waiting times. Here we introduce `leapfrog' moves to second-neighbour minima, which prevent the KMC trajectory oscillating between structures separated by low barriers. In the second approach we successively remove minima from the intervening set, renormalising the branching probabilities and waiting times to preserve the mean first-passage times of interest. Regrouping the local minima appropriately is also shown to speed up the kinetic analysis dramatically at low temperatures. Applications are described where rates are extracted for databases containing tens of thousands of stationary points, with effective barriers that are several hundred times kT.Comment: 28 pages, 1 figure, 4 table

    Damage function for historic paper. Part I: Fitness for use

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    Background In heritage science literature and in preventive conservation practice, damage functions are used to model material behaviour and specifically damage (unacceptable change), as a result of the presence of a stressor over time. For such functions to be of use in the context of collection management, it is important to define a range of parameters, such as who the stakeholders are (e.g. the public, curators, researchers), the mode of use (e.g. display, storage, manual handling), the long-term planning horizon (i.e. when in the future it is deemed acceptable for an item to become damaged or unfit for use), and what the threshold of damage is, i.e. extent of physical change assessed as damage. Results In this paper, we explore the threshold of fitness for use for archival and library paper documents used for display or reading in the context of access in reading rooms by the general public. Change is considered in the context of discolouration and mechanical deterioration such as tears and missing pieces: forms of physical deterioration that accumulate with time in libraries and archives. We also explore whether the threshold fitness for use is defined differently for objects perceived to be of different value, and for different modes of use. The data were collected in a series of fitness-for-use workshops carried out with readers/visitors in heritage institutions using principles of Design of Experiments. Conclusions The results show that when no particular value is pre-assigned to an archival or library document, missing pieces influenced readers/visitors’ subjective judgements of fitness-for-use to a greater extent than did discolouration and tears (which had little or no influence). This finding was most apparent in the display context in comparison to the reading room context. The finding also best applied when readers/visitors were not given a value scenario (in comparison to when they were asked to think about the document having personal or historic value). It can be estimated that, in general, items become unfit when text is evidently missing. However, if the visitor/reader is prompted to think of a document in terms of its historic value, then change in a document has little impact on fitness for use

    A Game Theoretic Optimization Framework for Home Demand Management Incorporating Local Energy Resources

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    Facilitated by advanced ICT infrastructure and optimization techniques, smart grid has the potential to bring significant benefits to the energy consumption management. This paper presents a game theoretic consumption scheduling framework based on the use of mixed integer programming to schedule consumption plan for residential consumers. In particular, the optimization framework incorporates integration of locally generated renewable energy in order to minimise dependency on conventional energy and the consumption cost. The game theoretic model is designed to coordinatively manage the scheduling of appliances of consumers. The Nash equilibrium of the game exists and the scheduling optimization converges to an equilibrium where all consumers can benefit from participating in. Simulation results are presented to demonstrate the proposed approach and the benefits of home demand management
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